General and theoretical aspects of the peroxide group

2010 ◽  
pp. 1-84 ◽  
Author(s):  
Dieter Cremer
Keyword(s):  
2020 ◽  
Vol 17 (2) ◽  
pp. 172
Author(s):  
HARMAN AGUSAPUTRA ◽  
MARIA SUGENG ◽  
AYLY SOEKAMTO ◽  
ATIK WULANDARI

<p><strong>Abstract</strong></p><p><strong>Background:</strong> Hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) as antiseptic has been used frequently to clean woundsin in hospitals and clinics. Hydrogen peroxide has the effectof strong oxidative that can kill pathogens. It can clean up debris and necrotic tissuesin wounds. Hydrogen peroxidealso has hemostatic effect that can help to stop bleeding. Besides antiseptic effects, hydrogen peroxide i s suspected of having negative effect in wound healing. Hydrogen peroxide presumably could cause delayed wound healing by exudate formation and delayed epithelial growth.</p><p><strong>Method</strong>: This study was conducted in the laboratory using 48 white mice that were divided into 2 groups. All the mice were purposely wounded. Afterwards in one group the wounds were clean up using hydrogen peroxide, while in the other group without hydrogen peroxide as control. The wounds of both groups were observed on day 1, day 3 and day 7. On day 1 and day 3, both groups did not show significant difference.</p><p><strong>R</strong><strong>esult</strong> : on day 7 showed that the wound healing in hydrogen peroxide group were delayed. Fifty percent of them had the formation of exudate and 62.5% of them showed delayed epithelial growth.</p><p><strong>Conclusion </strong>: This study could show hydrogen peroxide as wound antiseptic has delayed wound healing effect.</p><p><strong>Keyword</strong>: hydrogen peroxide, wound healing</p>


Materials ◽  
2020 ◽  
Vol 13 (12) ◽  
pp. 2710 ◽  
Author(s):  
Maroun Ghaleb ◽  
Giovanna Orsini ◽  
Angelo Putignano ◽  
Sarah Dabbagh ◽  
Georges Haber ◽  
...  

This in vitro study aims to evaluate whether a solution of 10% sodium ascorbate (SA) may exert a beneficial effect on the bonding of composite to enamel after using different bleaching agents and protocols. Microtensile bond strength (µTBS) was evaluated on 72 freshly extracted human central incisors, divided into eight experimental groups and one control group (total n = 9): Group 1 serves as control (nonbleached). Group 2 was bleached with 5% carbamide peroxide. Group 3 was bleached with 5% carbamide peroxide and then treated with 10% SA. Group 4 was bleached with 10% carbamide peroxide. Group 5 was bleached with 10% carbamide peroxide, then treated with 10% SA. Group 6 was bleached with 16% carbamide peroxide. Group 7 was bleached with 16% carbamide peroxide, then treated with 10% SA. Group 8 was bleached with 6% hydrogen peroxide. Group 9 was bleached with 6% hydrogen peroxide, then treated with 10% SA. All groups were restored immediately after the different treatments using a resin composite. The µTBS values were measured using a universal testing machine and statistical analysis was performed by means of normality and variance analyses, SIDAK test for univariate test and multiple comparisons, and Student test to compare µTBS values of each group with the control. The mean µTBS values in groups 2, 4, 6, 8 were significantly lower than controls. For groups 3, 5, 7, 9, subjected to antioxidant (10% SA) application, all µTBS values increased significantly. However, only for Groups 3 and 5 there was no significant difference with the control. Applying 10% SA for 10 min may improve the bond strength composite/bleached enamel just when whitening is performed with 5% and 10% carbamide peroxide.


Marine Drugs ◽  
2018 ◽  
Vol 16 (8) ◽  
pp. 276 ◽  
Author(s):  
Chia-Chi Peng ◽  
Chiung-Yao Huang ◽  
Atallah Ahmed ◽  
Tsong-Long Hwang ◽  
Chang-Feng Dai ◽  
...  

Six new cembranoids, cherbonolides A−E (1–5) and bischerbolide peroxide (6), along with one known cembranoid, isosarcophine (7), were isolated from the Formosan soft coral Sarcophyton cherbonnieri. The structures of these compounds were elucidated by detailed spectroscopic analysis and chemical methods. Compound 6 was discovered to be the first example of a molecular skeleton formed from two cembranoids connected by a peroxide group. Compounds 1–7 were shown to have the ability of inhibiting the production of superoxide anions and elastase release in N-formyl-methionyl-leucyl-phenyl-alanine/cytochalasin B (fMLF/CB)-induced human neutrophils.


2015 ◽  
Vol 2 (1) ◽  
pp. 29
Author(s):  
Laily Maghfira Noor Ridarsyah ◽  
Djoko Priyanto ◽  
Grahita Aditya

Background: Infection control is essential in dentristry. Many studies suggested an increase of bacteria in dental unit due to back flow from ultrasonic scaler. Previous study states that hydrogen peroxidein 3% concentration may reduce the number of bacteria's colony of ultrasonic scaler water in RSIGM Sultan Agung Semarang significantly. Purpose: The aim of this study was to determine the effectiveness of hydrogen peroxide to kill bacteria of ultrasonic scaler water on dental unit in RSIGM Sultan Agung Semarang. Method: The type of research used in the study is quasy experimental with pretest-posttest design. The sample used in this study is 15 dental units which were divided into 3 groups group I 2% hydrogen peroxide, group II 4.5% hydrogen peroxide, and group III 6 % hydrogen peroxide and than flow it on ultrasonic scaler water and check the bakteria before and after experiment. Result: Based on the results of Wilcoxon test the comparison before and after at the three groups obtained the results of significance is less than 0.05. It can be concluded thathydrogen peroxide effectively kills bacteria of ultrasonic scaler water on dental unit in RSIGM Sultan Agung Semarang. Conclusion: From the results it can be concluded that the percentage of hydrogen peroxide which can cause all organisms die without disturbing the patient's health is at 4.5% and 6% concentration.


2016 ◽  
Vol 2 (3) ◽  
pp. 128
Author(s):  
Apriko Merza ◽  
Billy Sujatmiko ◽  
Rinda Yulianti

Comparing microhardness of dentine crown after application of various intracoronal bleaching agents. The aim of this study is to compare microhardness of dentine crown after treatment with intracoronal bleaching agents. The method of this study was an experimental laboratory. Thirty two extracted human mandibular first premolars without caries, sectioned at 2 mm below Cemento-Enamel Junction were divided into four groups and bleaching agents were sealed into the pulp chambers as follows: group A – 45% carbamide peroxide, group B – 35% hydrogen peroxide, group C – sodium perborate mixed aquadest and group D – aquadest. Access cavities were sealed and then stored in aquadest at 37 °C. Bleaching procedures were performed on days 0, 7, 14 and 21. After 28 days, the teeth were sectioned longitudinally, and planted on acrylyc. Microhardness of dentine crown was measured by vickers microhardness tester. One Way ANOVA and LSD were used to evaluate the effect of intracoronal bleaching agents on microhardness of dentine crown. The results showed that average values of microhardness of dentine crown on group A was 45,04 VHN, group B was 45,42 VHN, group C was 55,22 VHN and group D was 55,63 VHN. In clonclusion, there was si gnificantly different microhardness of dentine crown between group 45% carbamide peroxide and 35% hidrogen peroxide with sodium perborate mixed aquadest, but between group 45% carbamide peroxide with 35% hidrogen peroxide there was no significant difference.ABSTRAKTujuan penelitian ini untuk mengetahui perbandingan kekerasan mikro dentin mahkota setelah aplikasi berbagai bahan bleaching intrakoronal. Jenis penelitian ini merupakan penelitian eksperimental laboratoris. Sebanyak 32 gigi premolar pertama mandibula tanpa karies, telah diekstraksi, dipotong 2 mm di bawah cemento-enamel junction dibagi dalam 4 kelompok dan bahan bleaching dimasukkan ke dalam kamar pulpa, yaitu kelompok A – 45% karbamid peroksida, kelompok B -35% hidrogen peroksida, kelompok C - sodium perborat dikombinasikan dengan aquadest, dan kelompok D – aquadest. Akses kavitas ditutup kemudian disimpan di dalam aquadest dengan suhu 37 °C. Prosedur bleaching dilakukan pada hari ke-0, 7, 14 dan 21. Setelah 28 hari, mahkota gigi dipotong secara longitudinal dan salah satu bagian ditanam di akrilik. Nilai kekerasan mikro dentin mahkota diuji menggunakan Vickers microhardnes tester. One way ANOVA dan uji LSD digunakan untuk mengevaluasi pengaruh berbagai bahan bleaching intrakoronal terhadap kekerasan mikro dentin. Hasil penelitian menunjukkan nilai kekerasan mikro dentin mahkota pada kelompok A sebesar 45,04 VHN, kelompok B sebesar 45,42 VHN, kelompok C sebesar 55,22 VHN dan kelompok D sebesar 55,63 VHN. Kesimpulan dari penelitian ini terdapat perbedaan kekerasan mikro dentin mahkota yang signifikan antara kelompok 45% karbamid peroksida dan 35% hidrogen peroksida dengan sodium perborat dikombinasikan dengan aquadest, sedangkan antara kelompok 45% karbamid peroksida dengan 35% hidrogen peroksida tidak terdapat perbedaan yang signifikan.


1985 ◽  
Vol 63 (2) ◽  
pp. 275-277 ◽  
Author(s):  
Donald C. Wigfield ◽  
Sherry L. Perkins

The recent development of techniques in this and other laboratories has allowed the exploration of elemental mercury oxidations by compounds bearing the —O—O—H moiety. The peracid group appears to be a far more effective oxidant of mercury than the peroxide group, and both peracetic acid and m-chloroperbenzoic acid oxidize mercury at the trace level to both mercurous and mercuric forms.


Author(s):  
Ravi R. Patel ◽  
Bharti N. Karelia

Background: Acne vulgaris is a dermatological disorder characterised by formation of comedones and inflammatory lesions. Acne is one of the most common reason for visiting a dermatologist in early adulthood. The current line of management for mild to moderate acne is topical medications with antimicrobials and retinoids. The present study assessed the effectiveness and safety of topical combination therapy for mild to moderate acne vulgaris.Methods: An observational, prospective and comparative study conducted on newly diagnosed acne vulgaris patients who were treated with topical combination therapy. Changes in the total, inflammatory and non-inflammatory lesion counts, investigator global assessment (IGA) and dermatology life quality index (DLQI) scales were recorded to check effectiveness. Treatment emergent adverse events were recorded in suspected ADR reporting form for safety assessment.Results: Participants (n=97) were treated with three topical combination treatments either clindamycin-benzoyl peroxide (group-A), clindamycin-adapalene (group-B) or benzoyl peroxide-adapalene (group C). Majority of participants (42.3%) were treated with clindamycin-benzoyl peroxide group. Reduction from baseline of total, inflammatory and non-inflammatory lesion counts were highly significant within group comparison (p<0.001), but between group differences were not significant. Significant improvement in DLQI and IGA scores were noted in all three groups, but between group comparison showed no significant differences. All three groups were safe and well tolerated and equally improve participant’s quality of life.Conclusions: all three topical combination drugs for mild acne vulgaris had similar effectiveness in terms of reduction in acne lesions with similar safety profile.


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