The Impact Frailty, Co-morbidity and Ageing of the Respiratory System on the Unfavourable Prognosis of COVID-19

2020 ◽  
pp. 109-115
Author(s):  
Marilena De Guglielmo ◽  
Andrea Fabbo
Keyword(s):  
Respiratory System ◽  
Co Morbidity ◽  
Unfavourable Prognosis ◽  
The Impact

Zinc Depletion Increases Readmission in Older Patients: An Example of Interactions Between Nutrition and Disease

2017 ◽  
Vol 87 (1-2) ◽  
pp. 10-16 ◽  
Author(s):  
Salah Gariballa ◽  
Awad Alessa
Keyword(s):  
Nutritional Status ◽  
Inductively Coupled Plasma ◽  
Older Patients ◽  
Controlled Trial ◽  
Prognostic Indicators ◽  
Hospitalised Patients ◽  
Increased Risk ◽  
Co Morbidity ◽  
The Impact ◽  
Poor Nutrition

Abstract. Background: ill health may lead to poor nutrition and poor nutrition to ill health, so identifying priorities for management still remains a challenge. The aim of this report is to present data on the impact of plasma zinc (Zn) depletion on important health outcomes after adjusting for other poor prognostic indicators in hospitalised patients. Methods: Hospitalised acutely ill older patients who were part of a large randomised controlled trial had their nutritional status assessed using anthropometric, hematological and biochemical data. Plasma Zn concentrations were measured at baseline, 6 weeks and at 6 months using inductively- coupled plasma spectroscopy method. Other clinical outcome measures of health were also measured. Results: A total of 345 patients assessed at baseline, 133 at 6 weeks and 163 at 6 months. At baseline 254 (74%) patients had a plasma Zn concentration below 10.71 μmol/L indicating biochemical depletion. The figures at 6 weeks and 6 months were 86 (65%) and 114 (70%) patients respectively. After adjusting for age, co-morbidity, nutritional status and tissue inflammation measured using CRP, only muscle mass and serum albumin showed significant and independent effects on plasma Zn concentrations. The risk of non-elective readmission in the 6-months follow up period was significantly lower in patients with normal Zn concentrations compared with those diagnosed with Zn depletion (adjusted hazard ratio 0.62 (95% CI: 0.38 to 0.99), p = 0.047. Conclusions: Zn depletion is common and associated with increased risk of readmission in acutely-ill older patients, however, the influence of underlying comorbidity on these results can not excluded.

scholarly journals Age- and Sex-Specific In-Hospital Mortality after Myocardial Infarction in Routine Clinical Practice

2010 ◽  
Vol 2010 ◽  
pp. 1-11 ◽  
Author(s):  
Chizobam Ani ◽  
Deyu Pan ◽  
David Martins ◽  
Bruce Ovbiagele
Keyword(s):  
Myocardial Infarction ◽  
Proportional Hazards ◽  
Length Of Hospital Stay ◽  
Mortality Rates ◽  
Cox Proportional Hazards ◽  
Mortality Trends ◽  
Male Mortality ◽  
Co Morbidity ◽  
The Impact ◽  
Age And Sex

Background. Literature regarding the influence of age/sex on mortality trends for acute myocardial infarction (AMI) hospitalizations is limited to hospitals participating in voluntary AMI registries.Objective. Evaluate the impact of age and sex on in-hospital AMI mortality using a nationally representative hospital sample.Methods. Secondary data analysis using AMI hospitalizations identified from the Nationwide-Inpatient-Sample (NIS). Descriptive and Cox proportional hazards analysis explored mortality trends by age and sex from 1997–2006 while adjusting for the influence of, demographics, co-morbidity, length of hospital stay and hospital characteristics.Results. From 1997–2006, in-hospital AMI mortality rates decreased across time in all subgroups (), except for males aged <55 years. The greatest decline was observed in females aged <55 years, compared to similarly aged males, mortality outcomes were poorer in 1997-1998 (RR 1.47, 95% CI  =  1.30–1.66), when compared with 2005-2006 (RR 1.03, 95% CI  =  0.90–1.18), adjusted value for trend demonstrated a statistically significant decline in the relative AMI mortality risk for females when compared with males (<0.001).Conclusion. Over the last decade, in-hospital AMI mortality rates declined for every age/sex group except males <55 years. While AMI female-male mortality disparity has narrowed, some room for improvement remains.

scholarly journals COPD, Depression and COVID-19 Pandemic: A Harrowing, Demoralizing and Deleterious Triad

2021 ◽  
Vol 3 (8) ◽  
pp. 01-06
Author(s):  
Iqbal Akhtar Khan ◽  
Hamza Iltaf Malik
Keyword(s):  
Hospital Admissions ◽  
Hospital Readmissions ◽  
Public Health Problem ◽  
Well Being ◽  
Care Utilization ◽  
Global Public Health ◽  
Increased Risk ◽  
Co Morbidity ◽  
Pulmonary Manifestations ◽  
The Impact

COPD is a highly incapacitating global public health problem, with pulmonary and extra-pulmonary manifestations and usually associated with significant concomitant chronic diseases. With enhanced understanding, it has extensively been reported as a complex, heterogeneous and dynamic disease affecting patients’ health beyond pulmones. Depression, with prevalence of 322 million people, is a major contributor to the overall global burden of disease. In various epidemiological and clinical studies, its prevalence among patients with COPD varies from 18% to 80%. This deadly duo leads to excessive health care utilization rates and costs including increased rates of exacerbation, sub-optimal adherence to prescribed medications, increased hospital admissions, longer hospital stays and increased hospital readmissions. Moreover, there is increased risk of suicidal ideation, suicidal attempts, and suicidal drug overdose. It is a pity that, in significant cases, the co-morbidity remains under-recognized and under-treated. The impact of prevailing COVID 19 pandemic, on the dual burden of COPD and depression, and possible remedial measures including “The 6 ways to boost one’s well-being-by Mental Heath UK, “The Living with the Times” toolkit--by WHO” and innovative add-ons like Dance Movement Therapy and Musical Engagement Therapy have been discussed.

scholarly journals Cause-and-effect relationships between air pollution and health conditions in population

2020 ◽  
Vol 5 (4) ◽  
pp. 230-234
Author(s):  
I. I. Berezin ◽  
Yu. Yu. Eliseev ◽  
A. K. Sergeev
Keyword(s):  
Air Pollution ◽  
Allergic Rhinitis ◽  
Bronchial Asthma ◽  
Respiratory System ◽  
Air Pollutants ◽  
Preventive Measures ◽  
Industrial City ◽  
Cause And Effect ◽  
The Impact

Objectives to reveal cause-and-effect relationships in the system "air pollution morbidity of the population" in a large industrial city. Material and methods.The dynamics of the pollutants concentration, such as formaldehyde and benzopyrene, through the period of 20152017 was analyzed in relation to the indicators of the morbidity of the respiratory system in the population of Samara. In particular, the study focused on the ratio of allergic rhinitis and asthma cases and the concentration of the formaldehyde and benzopyrene. Results.The incidence of respiratory diseases and the general morbidity increased both among children (by 46.7%) and adults (by 11.4%). There was the causal correlation between the effect of benzopyrene on the development of allergic rhinitis and bronchial asthma in children(r = 0.57 and r = 0.76) and in adults (r = 0.45 and r = 0.51) in Samara. The significant differences between the level of the pollutants and the frequency of the respiratory system diseases were registered in children and adults in different areas of Samara. Discussion.As a result of the increase of the maximum allowable concentration (MAC) of formaldehyde in atmospheric air, this pollutant has now ceased to be a priority. The revealed negative correlations point to the absence of an adverse effect of formaldehyde on the development of allergic rhinitis and bronchial asthma in both children and adults in Samara. Conclusion.According to the results of the study, the preventive measures aimed at reducing the impact of main air pollutants on the health of children and adults in Samara were suggested. Their implementation is possible by the immediate informing of the executive authorities to ensure they can make timely management decisions to improve the quality of the environment.

scholarly journals TP10.2.11The consequences of COVID-19 on the colorectal red-flag cancer pathway- A 3 month review 2019 to 2020

2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
R Sarah Small ◽  
Rachael Coulson ◽  
Ian Mcallister
Keyword(s):  
Colorectal Cancer ◽  
Definitive Treatment ◽  
Data Sets ◽  
Patient Demographics ◽  
Cancer Services ◽  
Information Time ◽  
Co Morbidity ◽  
Red Flag ◽  
Time To First Treatment ◽  
The Impact

Abstract Aim The COVID-19 pandemic is an evolving healthcare challenge introducing greater burden on existing resources. With 1,100 people in Northern Ireland diagnosed with colorectal cancer (CRC) per annum, concerns over disruption of cancer services and secondary consequences have been highlighted. We aim to evaluate the impact of COVID-19 on the CRC red flag pathway in comparison to the pre-COVID era. Methods Two comparative data sets were compiled through retrospective analysis of red-flag colorectal referrals over a 3-month period for both April to June 2019 and 2020. A comprehensive review of each patient’s electronic care record and medical notes was completed. Patient demographics, co-morbidity, referral information, time to hospital appointment and investigation modality were documented. For patients identified with CRC the stage and time to first definitive treatment was documented. Results A total of 47 CRCs were identified from both red-flag referral groups; 25 CRCs 2019 compared to 22 in 2020. Median age at time of referral was 79 years in 2019 compared to 71 years in 2020. Time to outpatient review was significantly less during 2020 compared to 2019; 16 days and 31 days respectively (p &lt; 0.05). Time to first treatment was 103 days 2019 compared to 75 days 2020 (p &lt; 0.05). Advanced diagnostic stage or increased number of emergency hospital presentations in the COVID-19 period was not demonstrated. Conclusion Despite disruption of established colorectal cancer services during the COVID-19 pandemic, we demonstrated patients waited less time to outpatient review and intervention. With comparative cases of CRC to the pre-COVID era diagnosed.

scholarly journals FEATURES FOR THE RESPIRATORY SYSTEM DISEASES MORBIDITY IN THE CHILD POPULATION LIVING IN THE IMPACT AREA OF EMISSION COMPONENTS OF LARGE-SCALE ALUMINA PRODUCTION

2019 ◽  
pp. 28-33
Keyword(s):  
Comparative Analysis ◽  
Respiratory System ◽  
Large Scale ◽  
Poor Quality ◽  
Morbidity Rate ◽  
Alumina Production ◽  
Atmospheric Air ◽  
Child Population ◽  
Actual Attendance ◽  
The Impact

We made hygienic assessment of the atmospheric air quality of the observation territory and comparison according to monitoring and field observations, carried out a comparative analysis of the respiratory system diseases morbidity of the child population according to the form of federal statistical observation and actual attendance for medical care for 2014–2017, evaluated the relationship of respiratory system diseases morbidity with the effects of the studied chemical factors. Atmospheric air poor quality for a number of substances has been established in the residential development of the observation territory. An increased morbidity rate of respiratory system diseases and certain nosological forms (chronic diseases of the tonsils and adenoids and bronchial asthma) in areas with stable atmospheric air pollution by emission components of large-scale alumina production has been established as a result of a comparative analysis of morbidity rates. We proved the dependence of the occurrence probability of additional cases of respiratory system diseases on the content in the atmospheric air of suspended solids, fine PM10, PM2.5 fractions, nitrogen dioxide, aluminum, manganese, solid and gaseous fluorides, chromium.

The impact of competition effort on the vital capacity of football players according to the playing positions.

2021 ◽  
Vol 20 (1) ◽  
pp. 0027
Author(s):  
فراس عبدالحميد خالد
Keyword(s):  
Respiratory System ◽  
Vital Capacity ◽  
Research Problem ◽  
Football Players ◽  
Youth Football ◽  
Post Test ◽  
Descriptive Approach ◽  
The Impact

The study focused on identifying the effect of competition effort on the level of vital capacity of young football players according to their playing centers. The researchers selected their sample from the (82) Fallujah clubs, the Golan club and the youth football stamina club, which numbered (82). The research problem focused on the lack of clarity of vision in identifying  The level of respiratory competence represented by the vital capacity of young football players according to their playing centers. The study aimed to know the immediate effect of competition effort on the level of vital capacity of young football players and to identify the level of that variable according to the centers of playing football.  For young football players and the existence of differences in the results of the post-test in the level of vital capacity of young players according to the centers of playing football. The researchers used the descriptive approach (case study) and conducted their pre and post tests according to the scientific foundations. The researchers concluded that the match effort has an effect on the level of vital capacity for all  Players are in different playing lines and that effect on the level of vital capacity was varied according to  The lines of play and the lines most affected was the midfield, followed by the defense line, then the offensive line and finally the goalkeepers. The researchers recommended that additional studies be conducted to know the effect of the match effort on other variables of the respiratory system and other functional devices and to conduct other studies to find out the effect of competition effort on other groups such as juniors and   advanced.

scholarly journals Impact of Comorbidities on Quality Of Life in Breast Cancer Patients

2016 ◽  
Vol 01 (04) ◽  
pp. 025-028
Author(s):  
Monica Irukulla ◽  
Rama Vaghmare ◽  
Deepa Joseph ◽  
Syed Ahmed ◽  
Jyothi Jonnadula ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Cancer Patients ◽  
Physical Functioning ◽  
Bodily Pain ◽  
Evidence Base ◽  
Breast Cancer Patients ◽  
Co Morbidity ◽  
The Impact

AbstractIntroduction: Comorbidities are common among cancer patients and with an aging population are becoming more prevalent. These can potentially affect the stage at diagnosis, treatment and outcomes of people with cancer. Despite the intimate relationship between comorbidity and cancer, there is limited consensus on how to record, interpret or manage comorbidities in the context of cancer. Addressing the impact of comorbid conditions in cancer patients warrants improvement in the evidence base from which to make treatment decisions for those with comorbidities.Methods: In this prospective study, 64 patients with breast cancer, underwent QOL assessment using FACT –B questionnaire at three time points- pre-radiation and three and six months post radiation.Results: 29(46%) patients had comorbidities of which 23 (35%) had cardiovascular comorbidities and 6 had other comorbidities. The co-morbidities were negatively associated with multiple domains of quality of life, including physical functioning, general health, bodily pain. Patients with diabetes and hypertension had significantly lower scores in physical functioning in comparison to patients without diabetes and hypertension, but improved after treatment. In majority of patients the overall scores were less in patients with co-morbidities compared to patients without any co-morbidity.Conclusion: Comorbidities can significantly affect the quality of life in patients with comorbidities. Hence greater research into the QOL issues for better patient care and symptom management especially during the transitioning phase from active care to follow up will help clinicians improve the quality of care and interdisciplinary co-ordination.

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