From 3D printing to 3D bioprinting: the material properties of polymeric material and its derived bioink for achieving tissue specific architectures

2022 ◽  
Author(s):  
Nihal Engin Vrana ◽  
Sharda Gupta ◽  
Kunal Mitra ◽  
Albert A. Rizvanov ◽  
Valeriya V. Solovyeva ◽  
...  
Keyword(s):  
3D Printing ◽  
Polymeric Material ◽  
Material Properties ◽  
3D Bioprinting ◽  
Tissue Specific

scholarly journals 3D Printed Chromophoric Sensors

Chemosensors ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 317
Author(s):  
Zachary Brounstein ◽  
Jarrod Ronquillo ◽  
Andrea Labouriau
Keyword(s):  
Thermal Stability ◽  
3D Printing ◽  
Material Properties ◽  
Chemical Structure ◽  
Elevated Temperatures ◽  
Advanced Manufacturing ◽  
Color Changes ◽  
Printed Sensors ◽  
3D Printed ◽  
Manufacturing Techniques

Eight chromophoric indicators are incorporated into Sylgard 184 to develop sensors that are fabricated either by traditional methods such as casting or by more advanced manufacturing techniques such as 3D printing. The sensors exhibit specific color changes when exposed to acidic species, basic species, or elevated temperatures. Additionally, material properties are investigated to assess the chemical structure, Shore A Hardness, and thermal stability. Comparisons between the casted and 3D printed sensors show that the sensing devices fabricated with the advanced manufacturing technique are more efficient because the color changes are more easily detected.

scholarly journals Microstructural Control of Polymers Achieved Using Controlled Phase Separation During 3D Printing with Oligomer Libraries: Dictating Drug Release for Personalized Subdermal Implants

2020 ◽  
Author(s):  
Laura Ruiz-Cantu ◽  
Gustavo Trindade ◽  
Vincenzo Taresco ◽  
Zuoxin Zhou ◽  
Laurence Burroughs ◽  
...  
Keyword(s):  
Phase Separation ◽  
3D Printing ◽  
Drug Release ◽  
Material Properties ◽  
High Throughput Screening ◽  
Ink Jet ◽  
Versatile Tool ◽  
3D Printed ◽  
Subdermal Implants ◽  
Level Of Understanding

<p>Controlling the microstructure of materials by means of phase separation is a versatile tool for optimizing material properties. In this study, we show that ink jet 3D printing of polymer blends gives rise to controllable phase separation that can be used to tailor the release of drugs. We predicted phase separation using high throughput screening combined with a model based on the Flory-Huggins interaction parameter, and were able to show that drug release from 3D printed structures can be predicted from observations based on single drops of mixtures. This new understanding gives us hierarchical compositional control, from droplet to device, allowing release to be ‘dialed up’ without any manipulation of geometry. This is an important advance for implants that need to be delivered by cannula, where the shape is highly constrained and thus the usual geometrical freedoms associated with 3D printing cannot be exploited, bringing a hitherto unseen level of understanding to emergent material properties of 3D printing.</p>

scholarly journals Discovering new 3D bioprinting applications: Analyzing the case of optical tissue phantoms

2018 ◽  
Vol 5 (1) ◽  
Author(s):  
Marisela Rodriguez-Salvador
Keyword(s):  
Optical Properties ◽  
3D Printing ◽  
Clinical Training ◽  
Three Dimensional ◽  
Biological Tissues ◽  
3D Bioprinting ◽  
Technology Intelligence ◽  
Biomedical Device ◽  
Tissue Phantoms ◽  
Scientific Papers

Optical tissue phantoms enable to mimic the optical properties of biological tissues for biomedical device calibration, new equipment validation, and clinical training for the detection, and treatment of diseases. Unfortunately, current methods for their development present some problems, such as a lack of repeatability in their optical properties. Where the use of three-dimensional (3D) printing or 3D bioprinting could address these issues. This paper aims to evaluate the use of this technology in the development of optical tissue phantoms. A competitive technology intelligence methodology was applied by analyzing Scopus, Web of Science, and patents from January 1, 2000, to July 31, 2018. The main trends regarding methods, materials, and uses, as well as predominant countries, institutions, and journals, were determined. The results revealed that, while 3D printing is already employed (in total, 108 scientific papers and 18 patent families were identified), 3D bioprinting is not yet applied for optical tissue phantoms. Nevertheless, it is expected to have significant growth. This research gives biomedical scientists a new window of opportunity for exploring the use of 3D bioprinting in a new area that may support testing of new equipment and development of techniques for the diagnosis and treatment of diseases.

scholarly journals Fabrication of 3D Printing Scaffold with Porcine Skin Decellularized Bio-Ink for Soft Tissue Engineering

Materials ◽  
2020 ◽  
Vol 13 (16) ◽  
pp. 3522
Author(s):  
Su Jeong Lee ◽  
Jun Hee Lee ◽  
Jisun Park ◽  
Wan Doo Kim ◽  
Su A Park
Keyword(s):  
Tissue Engineering ◽  
Extracellular Matrix ◽  
3D Printing ◽  
Three Dimensional ◽  
3D Bioprinting ◽  
Research Groups ◽  
Porcine Skin ◽  
Alginate Hydrogel ◽  
Chemical Treatments ◽  
Soft Tissue Engineering

Recently, many research groups have investigated three-dimensional (3D) bioprinting techniques for tissue engineering and regenerative medicine. The bio-ink used in 3D bioprinting is typically a combination of synthetic and natural materials. In this study, we prepared bio-ink containing porcine skin powder (PSP) to determine rheological properties, biocompatibility, and extracellular matrix (ECM) formation in cells in PSP-ink after 3D printing. PSP was extracted without cells by mechanical, enzymatic, and chemical treatments of porcine dermis tissue. Our developed PSP-containing bio-ink showed enhanced printability and biocompatibility. To identify whether the bio-ink was printable, the viscosity of bio-ink and alginate hydrogel was analyzed with different concentration of PSP. As the PSP concentration increased, viscosity also increased. To assess the biocompatibility of the PSP-containing bio-ink, cells mixed with bio-ink printed structures were measured using a live/dead assay and WST-1 assay. Nearly no dead cells were observed in the structure containing 10 mg/mL PSP-ink, indicating that the amounts of PSP-ink used were nontoxic. In conclusion, the proposed skin dermis decellularized bio-ink is a candidate for 3D bioprinting.

scholarly journals Individual cell-only bioink and photocurable supporting medium for 3D printing and generation of engineered tissues with complex geometries

2019 ◽  
Vol 6 (8) ◽  
pp. 1625-1631 ◽  
Author(s):  
Oju Jeon ◽  
Yu Bin Lee ◽  
Hyoen Jeong ◽  
Sang Jin Lee ◽  
Derrick Wells ◽  
...  
Keyword(s):  
3D Printing ◽  
Structural Control ◽  
Individual Cell ◽  
Complex Geometries ◽  
3D Bioprinting ◽  
Long Term Culture ◽  
Engineered Tissues ◽  
Cellular Condensation

Functional tissues with complex geometries can be engineered by 3D bioprinting individual cell-only bioinks into a photocrosslinkable microgel support bath, which permits structural control over cellular condensation formation and long-term culture.

scholarly journals Chemical insights into bioinks for 3D printing

2019 ◽  
Vol 48 (15) ◽  
pp. 4049-4086 ◽  
Author(s):  
Laurine Valot ◽  
Jean Martinez ◽  
Ahmad Mehdi ◽  
Gilles Subra
Keyword(s):  
3D Printing ◽  
Cell Survival ◽  
3D Bioprinting ◽  
Chemical Strategies

Dedicated chemical strategies are required to form hydrogel networks from bioink components, allowing cell survival during 3D bioprinting processes.

scholarly journals The multiaxial behavior of filled polypropylene parts by drop-weight impact test

2018 ◽  
Vol 210 ◽  
pp. 05013 ◽  
Author(s):  
Ales Mizera ◽  
Martin Mizera ◽  
Milan Navratil ◽  
Stepan Sanda ◽  
Michal Opocensky
Keyword(s):  
Polymeric Material ◽  
Glass Fibre ◽  
Impact Loading ◽  
Material Properties ◽  
Impact Test ◽  
Impact Behavior ◽  
Suitable Choice ◽  
Penetration Test ◽  
Weight Impact ◽  
The Impact

This study deals with the multiaxial behaviour of reinforced polypropylene with 30 % of glass fibre (PP30GF) and virgin polypropylene (PP). The impact behavior of these two materials is very needed to know for the possible modification of these two materials to obtain the better material properties. The injection moulded PP, and PP30GF samples were subjected to the penetration test at different set potential energies, and the results were subsequently evaluated and discussed. It was found out that PP has better behaviour at the multiaxial stress than PP30GF. It is possible to claim that for the application more demanding to the impact loading, pure PP is more suitable choice of the polymeric material.

Exploring the Multi-Stage Effects of Material Preparation and Printing on 3D Printing Product Quality

2019 ◽  
Author(s):  
Sahand Hajifar ◽  
Ramanarayanan Purnanandam ◽  
Hongyue Sun ◽  
Chi Zhou
Keyword(s):  
3D Printing ◽  
Material Properties ◽  
Good Property ◽  
Metal Powders ◽  
Promising Technique ◽  
Printing Process ◽  
Multi Stage ◽  
Flexible Parts ◽  
Printing Processes ◽  
Material Preparation

Abstract 3D printing is a promising technique to fabricate flexible parts and reduce the supply chain. Various materials, such as metal powders, plastics, ultraviolet (UV) sensitive resins, can be fabricated from 3D printing and form the final printed part. Currently, most researchers either focus on exploring printable materials with good property or focus on the process quality control given a certain type of material. However, for many 3D printing processes, the printing process and product properties are dependent on both the material properties and process settings. To the best of the authors’ knowledge, the quantitative analysis of the interactions of material properties and printing process settings are rarely studied. In this paper, we treat the material preparation and 3D printing as different manufacturing stages, and we explore the multi-stage effects in 3D printing. In particular, we add carbon fiber to the CLEAR resin to alter the material properties for a stereolithography (SLA) 3D printing process. It is observed that the part properties are jointly affected by material properties and printing process settings. Therefore, the material property and process settings should be jointly considered for optimizing 3D printing processes.

scholarly journals Particle size influence on material properties of BaTiO3 ceramics fabricated using freeze-form extrusion 3D printing

2019 ◽  
Vol 6 (11) ◽  
pp. 115211 ◽  
Author(s):  
Anabel Renteria ◽  
Jorge A Diaz ◽  
Baitong He ◽  
Ivan A Renteria-Marquez ◽  
Luis A Chavez ◽  
...  
Keyword(s):  
Particle Size ◽  
3D Printing ◽  
Material Properties

scholarly journals Material Extrusion Additive Manufacturing of Wood and Lignocellulosic Filled Composites

Polymers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2115
Author(s):  
Meghan E. Lamm ◽  
Lu Wang ◽  
Vidya Kishore ◽  
Halil Tekinalp ◽  
Vlastimil Kunc ◽  
...  
Keyword(s):  
Additive Manufacturing ◽  
3D Printing ◽  
Present State ◽  
Material Properties ◽  
Large Scale ◽  
State Of The Art ◽  
Material Extrusion ◽  
Functional Additives ◽  
Natural Filler ◽  
Natural Fillers

Wood and lignocellulosic-based material components are explored in this review as functional additives and reinforcements in composites for extrusion-based additive manufacturing (AM) or 3D printing. The motivation for using these sustainable alternatives in 3D printing includes enhancing material properties of the resulting printed parts, while providing a green alternative to carbon or glass filled polymer matrices, all at reduced material costs. Previous review articles on this topic have focused only on introducing the use of natural fillers with material extrusion AM and discussion of their subsequent material properties. This review not only discusses the present state of materials extrusion AM using natural filler-based composites but will also fill in the knowledge gap regarding state-of-the-art applications of these materials. Emphasis will also be placed on addressing the challenges associated with 3D printing using these materials, including use with large-scale manufacturing, while providing insight to overcome these issues in the future.

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