The Relationship Between Inflammatory Marker Levels and Pulmonary Tuberculosis Severity

Inflammation ◽  
2014 ◽  
Vol 38 (2) ◽  
pp. 691-696 ◽  
Author(s):  
Ozlem Abakay ◽  
Abdurrahman Abakay ◽  
Hadice Selimoglu Sen ◽  
Abdullah C. Tanrikulu
2018 ◽  
Vol 6 (2) ◽  
pp. 30-35
Author(s):  
Ade Ella Nur Rizky Oktaviyanti

One of the factors that influence compliance is individual motivation. There are still many pulmonary tuberculosis patients who do not wear masks, this can have an impact on disease transmission. Poor individual motivation can affect someone's compliance. The purpose of this research is to determine the relationship of patient motivation regarding prevention of transmission with adherence to the use of masks in patients with pulmonary tuberculosis in Rambipuji Health Center, Jember Regency. This research uses descriptive correlative type of research. In this study using a cross-sectional approach. The sample of this study was taken using simple random sampling, namely pulmonary tuberculosis patients at the Rambipuji Health Center in Jember Regency, totaling 105 patients but only 50 patients were used as samples. This research was conducted by giving a questionnaire to pulmonary tuberculosis patients to find out the patient's motivation about preventing transmission by adhering to the use of masks. The results of the study were analyzed using the Lambda Correlation Test, the results of the analysis found that the motivation of patients was good motivation (22%), patient motivation was sufficient (56%), and patient motivation was less motivation (22%). Whereas adherence to the use of masks in pulmonary tuberculosis patients is compliant (36%), and non-compliant (64%). The Lambda Correlation Test results obtained from the variable compliance with ρ = 0.389 positive direction with a value of ρ count of 0.027 <0.05 which means there is a relationship between patient motivation about prevention of transmission with compliance with the use of masks in patients with pulmonary tuberculosis in Rambipuji Health Center, Jember District. It is recommended that further studies be able to conduct more in-depth research related to the relationship of patient motivation regarding the prevention of transmission with adherence to the use of masks in pulmonary tuberculosis patients


2017 ◽  
Vol 1 (2) ◽  
pp. 70 ◽  
Author(s):  
Rambu Beppy Hamuaty ◽  
Indriyanti Rafi Sukmawati ◽  
Ferry Sandra

Background: Interaction between advanced glycation end product (AGE) and receptor for AGE (RAGE) triggers the escalation of inflammatory cytokine expressions. High-sensitivity C-reactive protein (hsCRP), an important inflammatory marker, has been reported to be modulated by soluble RAGE (sRAGE). However, the relationship between hsCRP and sRAGE in diabetes was not clearly described. Therefore present study was conducted to determine the relationship between sRAGE with hsCRP in men with central obese diabetic and non-diabetic. Materials and Methods: Adult men aged 25-60 years with central obese diabetes and non-diabetes, were recruited. Patient’s profiles were collected before the physical and blood examination. Physical examinations were conducted by measuring waist/abdomen, blood pressure, height, and weight. The routine blood test was performed to obtain concentrations of fasting blood glucose, HbA1c, hsCRP and sRAGE level.Results: Fifty-seven subjects with central obese and waist size ≥90 cm were selected. It was found that hsCRP values were significantly different (p=0.000) in HbA1c <6.5% dan HbA1c ≥6.5% groups. There was an inverse relationship between hsCRP and sRAGE levels for both in HbA1c <6.5% (r=-0.073) and HbA1c≥6.5% (r=-0.022) groups. In HbA1c ≥6.5% group, sRAGE showed strong positive correlation with 1 mg/dL ≤ hsCRP <3 mg/dL group (r>0.5).Conclusions: In the early stages of diabetes with hsCRP <1 mg/dL, the protective function was demonstrated with greater sRAGE levels. However, in further phase with 3 ≤ hsCRP < 10 mg/dL, the level of sRAGE was low, which is assumed to be associated with complications. Hence, sRAGE could be suggested as a complementary marker for hsCRP to evaluate diabetic men with central obesity.Keywords: sRAGE, hsCRP, diabetes, HbA1c, central obesity


1991 ◽  
Vol 20 (2) ◽  
pp. 435-440 ◽  
Author(s):  
J H SCHOEMAN ◽  
MARGARET S WESTAWAY ◽  
ARIANE NEETHLING

2021 ◽  
Vol 1 (2) ◽  
pp. 538-547
Author(s):  
Fitri Zulfa Hayati ◽  
Nurhapipa Nurhapipa ◽  
Nila Puspita Sari

Tuberkulosis Paru merupakan penyakit menular yang disebabkan oleh bakteri Mycobacterium tuberculosis. Kejadian penyakit Tuberkulosis Paru di Puskesmas Rejosari Kota Pekanbaru merupakan kasus tertinggi di kota pekanbaru sebanyak 798 kasus. Tujuan penelitian ini secara umum untuk mengetahui hubungan kondisi fisik rumah dan status gizi dengan insiden penyakit tuberkulosis paru. Penelitian ini adalah analitik kuantitatif dengan pendekatan Case Control. Populasi kasus dalam penelitian ini yaitu seluruh penderita Tuberkulosis Paru. Sampel penelitian yaitu 18 responden kelompok kasus dan 72 responden kelompok kontrol dengan menggunakan teknik Simple random sampling. Lokasi penelitian dilakukan di Wilayah Kerja Puskesmas Rejosari Kota Pekanbaru pada bulan Juli – Agustus 2020. Alat ukur yang digunakan yaitu kuesioner, roll meter, lux meter, dan timbangan berat badan. Analisis data dilakukan secara univariat dan bivariat menggunakan uji Chi Square. Hasil uji statistik hubungan dari setiap variabel semuanya berhubungan dengan insiden penyakit tuberkulosis paru, yaitu variabel luas ventilasi (p = 0,002, OR = 7,857), kepadatan hunian (p = 0,003, OR = 5,500), pencahayaan (p = < 0,05, OR = 8,500), dan status gizi (p = 0,001, OR = 10,818). Diharapkan kepada tim pencegah dan pengendalian penyakit tuberkulosis paru Puskesmas Rejosari meningkatkan penyuluhan atau pemahaman langsung kepada masyarakat penderita TB paru serta membentuk dan melatih kader – kader untuk penanggulangan Tuberkulosis Paru. Diharapkan masyarakat selalu membuka jendela agar udara dan cahaya dapat masuk ke dalam rumah serta menjaga pola makan yang seimbang dan sehat. Pulmonary Tuberculosis is an infectious disease caused by the bacteria Mycobacterium tuberculosis. The incidence of pulmonary tuberculosis in Rejosari Primary Health Center Pekanbaru City is the highest case in Pekanbaru city with 798 cases. The purpose of this study in general was to determine the relationship between the physical condition of the house and nutritional status with the incidence of pulmonary tuberculosis. This research is a quantitative analytic with a Case Control approach. The populations of cases were all patients with pulmonary tuberculosis. The research sample was 18 respondents in the case group and 72 respondents in the control group using the simple random sampling technique. The research location was carried out in the Rejosari Public Health Center, Pekanbaru City in July - August 2020. The measuring instruments used were questionnaires, roll meters, lux meters, and weight scales. Data analysis was performed univariate and bivariate using the Chi Square test. The statistical test results of the relationship between each variable were all related to the incidence of pulmonary tuberculosis, namely the variable area of ventilation (p = 0.002, OR = 7.857), occupancy density (p = 0.003, OR = 5,500), lighting (p =0.05, OR 8.5)and nutritional status (p = 0.001, OR = 10.818). It is hoped that the team for preventing and controlling pulmonary tuberculosis at the Rejosari Community Health Center will increase direct education or understanding to people with pulmonary tuberculosis and form and train cadres to control pulmonary tuberculosis. It is hoped that people will always open windows so that air and light can enter the house and maintain a balanced and healthy diet.


2021 ◽  
Vol 2 (1) ◽  
pp. 97-104
Author(s):  
Andre Christian Ginting ◽  
Andrico Napolin Lumbantobing

A B S T R A C TIntroduction Tuberculosis is an infectious disease caused by bacteria in the form ofrods (bacilli) known as Mycobacterium tuberculosis. This disease is included as achronic infectious disease. The causes of the increase in TB cases each year are stillvarious. One of them is smoking behavior. A person who smokes will have twice therisk of contracting TB. This study aims to determine the relationship between smokingbehavior and the incidence of pulmonary tuberculosis in the work area of the MedanSunggal Puskesmas in 2019. Methods This study is an analytical study with a crosssectional design. The population of this study were patients with pulmonary TB in thework area of the Medan Sunggal Public Health Center in 2019. The sample size usedwas 104 people who had met the inclusion and exclusion criteria. In the second study,the data collection tool was through the Puskesmas medical records. Data analysis wasperformed using the statistical test is chi square. Results the result showed that therewas a relationship between smoking behavior and the incidence of pulmonarytuberculosis in Medan Sunggal Public Health Center with an OR (95% CI) value of105,125 (13,280-832,161), which means that respondents who smoke will have105,125 times the risk of suffering from pulmonary tuberculosis compared to non-smoking respondents. From the results of 95% CI, it can be seen that the lower limitand upper limit values (CI values) not include 1.00, so the results of the study arestatistically significant at the value of α = 0.001. Conclusion. Smoking behavior hasan insignificant relationship with the incidence of pulmonary tuberculosis at MedanSunggal Puskesmas in 2019. It is recommended that the primary care should providesupport and sources of information about smoking habits, especially for patients whohave been diagnosed with pulmonary TB.


2021 ◽  
Vol 2 (3) ◽  
pp. 16-22
Author(s):  
Mamura Saidova ◽  
◽  
Svetlana Khodjaeva

The article is devoted to current issues of psychological rehabilitation of patients with pulmonary tuberculosis. The article focuses on the specifics of psychological assistance. Itsubstantiates the need to organize special psychocorrectional programs aimed at overcoming premorbid elements of the relationship system, which are considered as psychological risk factors for the occurrence of the tuberculous process and its relapses.Keywords:pulmonary tuberculosis, psychological rehabilitation, premorbid personality characteristics, relationship system, therapeutic targets


2016 ◽  
Vol 14 (2) ◽  
pp. 45
Author(s):  
Mudiyono Mudiyono ◽  
Nur Endah Wahyuningsih ◽  
M. Sakundarno Adi

Background: Children’s Tuberculosis (TB) in Indonesia at 2013 was fourth ranks in the world. The cases of children’s pulmonary tuberculosis in Pekalongan at 2013 be amounted 88 (32%) of the total cases of TB (271), greater than 8% of national cases. Children’s pulmonary tuberculosis is a disease that can be cured and are not duly claimed the lives of children. The purpose of this study is analyze the relationship between the mother's behavior and physical environment house of children with the incidence of children’s pulmonary tuberculosis in Pekalongan City.Methods: The study was observational with case control design. The cases are pulmonary tuberculosis patients and control are child is not a child’s pulmonary tuberculosis. The subjects were 50 cases and 50 controls. Results: The results of the bivariate analysis are associated with incidence population density with children’s pulmonary tuberculosis (p = <0.001), ventilation (p = 0.004), temperature of room (p = 0.036), density occupancy (p = <0.001) and natural lighting (p = 0.016). The results of multivariate analysis are risk factor for the incidence of children’s pulmonary tuberculosis with mother’s knowledge (p = 0.049; OR = 2.918; 95% CI = 1.005 to 8.472), density occupancy (p = 0.020; OR = 3.379; 95% CI = 1.212 to 9.417), humidity (p = 0.025; OR = 3.236; 95% CI = 1.156 to 9.058) and ventilation (p = 0.022; OR = 3.224; 95% CI = 1.182 to 8.797).Conclusion: The density occupancy, humidity, ventilation, mother’s knowledge are a risk factor pulmonary TB incidence of children in Pekalongan City.  Keywords: Behavior Mother, the physical environment house, children’s pulmonary tuberculosis, Pekalongan City.


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