High Prevalence of Low Birth Weight Babies Born to Pregnant Women Referred to a District Hospital in Rural Zambia

Author(s):  
Julie M. Buser ◽  
Carol J. Boyd ◽  
Cheryl A. Moyer ◽  
Davy Zulu ◽  
Alice Ngoma-Hazemba ◽  
...  
2020 ◽  
Vol 1 (1) ◽  
pp. 16
Author(s):  
Hatijar Hatijar

Low birth weight babies are babies born with a weight less than 2500 grams. LBW (low birth weight) affects the high mortality rate in infants and is at risk of experiencing obstacles in growth and development. LBW is generally caused due to lack of nutrition and nutritional needs from mother to fetus while pregnant women aged less than 20 years and more than 35 years have the risk of giving birth to LBW. The purpose of this study is to determine the risk factors that cause LBW based on maternal age and nutritional status. The research method used was observational with a cross sectional study approach. The sampling technique was random sampling at the Regional Haji Makassar General Hospital in the January to July 2015 period with a total sample of 65 people. Analysis using the Chi Square Test. The results showed that there was a relationship between maternal age, nutritional status of LBW with a value (p value = 0.00 <α = 0.05). Maternal age and nutritional status are factors that influence low birth weight where the results of the study indicate that there is a relationship between maternal age and nutritional status on the incidence of low birth weight. To reduce the incidence of low birth weight, it is necessary to increase counseling about the causes of low birth weight babies by health workers, especially midwives to pregnant women to prevent the risk of low birth weight birth.


2018 ◽  
Vol 6 (1) ◽  
Author(s):  
Sri Aminingsih ◽  
Nadiya Istiqomah

Background: Smoking affects blood circulation and makes mothers and babies exposedto hazardous chemicals. Every time a mother smokes, her baby gets less oxygen.Nicotine in cigarettes decreases blood flow to the placenta. At the same time carbonmonoxide (CO) lowers the amount of oxygen carried by blood. In addition, there are toxicchemicals that usually interfere the development of infants (Rahmalia, 2009). Apreliminary study conducted by the author at the Maternity House of Sri Panuntun, PedanKlaten District, there were 30 babies born in August to September 2017, revealed thatthere were 6 babies suffered from low birth weight, while 24 babies have normal birthweight.The purpose: Describing the relationship of pregnant women passive smokers with theincidence of Low Birth Weight was the aim of this study.The subjects : The population in this study was all mothers who gave birth at MaternityMother Sri Panuntun Klaten in January-March 2018 accounted for 55 respondents.The results: The result of this research by using Pearson Chi-Square correlation testobtained p = 0.000.The conclusion: There was a positive correlation between pregnant women who arepassive smokers with the incidence of low birth weight babies.Keywords: Pregnant women, Passive smokers, Low birth weight babies.


Author(s):  
Bhanwar Singh Meena ◽  
Harendra Kumar Netra ◽  
Amit Kumar Joshi ◽  
Krishna Priya Banerjee

Background: Maternal and perinatal morbidities are well-documented complications of pregnancy in women with thyroid dysfunction, both clinical and subclinical. About 2–5% of pregnant women suffer from thyroid disorders and timely intervention can be done if detected early. The presence of anti-TPO Ab is associated with increased rate of pregnancy complications such as miscarriage, preterm delivery, placental abruption, pregnancy-induced hypertension, intrauterine death and low birth weight. Objectives: Study the effect of anti-TPO Ab positivity on pregnancy outcome especially birth weight and estimate the prevalence of anti-TPO Ab in euthyroid pregnant women. Methods: This observational study enrolled 500 euthyroid pregnant women, age 20-35 years, up to 20 weeks gestation. Venous blood samples collected and analyzed for the anti-TPO Ab levels. On the basis of Ab positivity they were divided into anti-TPO Ab positive and Ab negative group. These two groups were followed up till delivery and compared fetal outcomes for birth weight. Result: Prevalence of anti-TPO Ab positivity was 5.2% in euthyroid obstetric women. Most of anti-TPO Ab positive women were overweight. Incidence of low birth weight babies was 4 fold higher in anti-TPO Ab positive women. Conclusion: Anti-TPO Ab positivity significantly associated with prepregnancy BMI and low birth weight of newborns. Keywords: Thyroid peroxidase antibodies, Anti-TPO Ab, Euthyroid, Low birth weight.


Nutrients ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1275 ◽  
Author(s):  
Aaron Chikakuda ◽  
Dayeon Shin ◽  
Sarah Comstock ◽  
SuJin Song ◽  
Won Song

Prenatal iron and folic acid (IFA) supplements are offered free to all pregnant women in Malawi to reduce maternal anemia and improve birth outcomes. We investigated the association between self-reported compliance to IFA intake and risk of low birth weight (LBW). Pregnant women who attended Bwaila Maternity Wing of Lilongwe District Hospital for delivery were recruited (n = 220). We used a questionnaire to collect self-reported information on IFA use and maternal sociodemographic data. Before delivery, blood samples for maternal hemoglobin (Hb) and folate status, and upon delivery, birth weight, and other newborn anthropometrics were measured. We used multivariable logistic regression to determine risk of LBW by prenatal IFA intake. The self-reported number of IFA pills taken during pregnancy was positively associated with Hb, but not serum and RBC folate concentration: <45, 45–89 and ≥90 pills taken corresponded with mean (SD) Hb 10.7 (1.6), 11.3 (1.8), and 11.7 (1.6) g/dL, respectively (p = 0.006). The prevalence of LBW was 20.1%, 13.5% and 5.6% for those who reported taking IFA pills <45, 45–89, and ≥90 pills, respectively (p = 0.027). Taking >60 IFA pills reduced risk of LBW delivery (OR (95% CI) = 0.15 (0.03–0.70), p = 0.033) than taking ≤30 pills. Self-reported compliance to IFA use is valid for assessing prenatal supplement program in Malawi, especially Hb status, and can reduce the rate of LBW.


2016 ◽  
Vol 5 (11) ◽  
pp. 5021 ◽  
Author(s):  
Singh S. ◽  
Karra V. K. ◽  
Daga M. K. ◽  
Kumar A. ◽  
Husain S. A. ◽  
...  

Hepatitis E has both a high incidence and severe course in pregnant women in some geographic regions of HEV (Hepatitis E virus) endemic countries. Intrauterine fetal death, preterm delivery, and perinatal mortality are reported to be higher in pregnant women with HEV infection. Alteration in the steroid hormone levels show high incidence of FHF (Fulminant Hepatic Failure) with high mortality in hepatitis E during pregnancy. The present study is designed to look for the association between ESR (Estrogen Receptor)-beta gene polymorphism for Alu I restriction site and pregnancy outcome. The study group comprised of 142 pregnant women with HEV infection in third trimester, 103 AVH (Acute Viral Hepatitis) cases and 39 ALF (Acute Liver Failure) cases. The control group comprised of 142, age and gestation matched healthy pregnant women with no obstetrics and medical complications. The inclusion criteria for the study group are pregnant women in third trimester with positivity to HEV IgM and/or HEV RNA in the age group of 18-40 years. Genomic DNA is extracted from peripheral blood leukocytes using DNA extraction kit according to the manufacturer’s instructions. The polymorphism study is done by using ESR2 specific primers and its genotype is determined by Alu I restriction enzyme. The occurrence of variant A allele for AluI restriction site is significantly higher in mothers with HEV infection who had preterm (25%) than full term delivery (10%) with OR 2.989 (95% CI = 1.265-8.084, p<0.05) and low birth weight (26.6%) than average birth weight (6.3%) babies with OR 5.399 (95% CI= 2.01-18.26, p<0.05) in pregnant women with HEV infection. The occurrence of variant A allele of ESR beta for AluI restriction site is significantly higher in mother of low birth weight babies (23%) than average birth weight babies (5.5%) in AVH group with OR 5.056 (95% CI= 1.634-21.57, p<0.05) and preterm (40.5%) than full term (0%) delivery in ALF group (p= 0.04). The higher occurrence of variant A allele for AluI restriction site of ESR-beta gene polymorphism is found to be associated with preterm delivery and low birth weight in pregnant women with HEV infection, preterm delivery in ALF group and low birth weight babies in AVH group.


2020 ◽  
Vol 10 (2) ◽  
pp. 1756-1759
Author(s):  
Anup Shrestha ◽  
Sabina Shrestha

Background: Anemia is one of the commonest health problems faced by pregnant women in both developing and developed countries. Maternal anemia is a potential risk factor for fatal outcomes like low birth weight and preterm delivery. This study intended at comparing the birth weight of the babies who were born to mothers with and without anemia during the third trimesters. Materials and methods: This study is a descriptive, cross-sectional study conducted at Kathmandu Medical College, Teaching Hospital from July 2019 to June 2020. The third-trimester hemoglobin of mothers was recorded along with the birth weight of their respective babies. Mothers with regular antenatal care visits at this hospital were included and the known causes for anemia like renal disorders, twin pregnancies, and others were excluded from the study. The third-trimester hemoglobin level of all pregnant females was correlated with the birth weight of the babies. Results: Out of a total of 2417 pregnant women, 317 (13%) had anemia. The overall prevalence of low birth weight was 12%. Out of 317 anemic mothers, 99 (31%) delivered low birth weight babies. Among those 99 low birth weight babies, 30 (30%) were preterm and 69 (70%) were term babies with the prevalence of low birth weight in anemic mothers being 31%. The correlation between maternal hemoglobin and birth weight was found to be statistically significant. Conclusions: Despite regular antenatal care, maternal anemia still prevails, affecting neonatal birth weight. There was a statistically significant correlation between maternal hemoglobin and birth weight (p-value <0.0001).


2016 ◽  
Vol 32 (1) ◽  
pp. 25
Author(s):  
Edy Marjuang Purba ◽  
Theodola Baning Rahayujati ◽  
Mohammad Hakimi

Teenage pregnancy and low birth weight infants in GunungkidulPurposeThis study aimed to determine any association between teenage pregnancy and low birth weight in Gunungkidul district.MethodThe study used a retrospective cohort design. Samples were 394 people consisting of 197 people in the case group and 197 people in the control group. Case group subjects were teenage pregnant women (<20 years), while control group subjects were adult pregnant women (≥20 years) and both groups delivered a live birth. Case group were taken from all health centers that had complete record and control group were taken using systematic random sampling.ResultsTeenage pregnancy increases the risk of low birth weight babies. Related external factors consist of chronic energy deficiency, anemia and antenatal care visits, while the level of education and hypertension were not related.ConclusionMothers suffering from less chronic energy and anemia increase the risk of giving birth to low birth weight babies, especially in teenage mothers.


2016 ◽  
Vol 6 (2) ◽  
pp. 116
Author(s):  
Afrina Begum ◽  
Joya Sree Roy ◽  
Nilufer Sultana ◽  
Noorjahan Begum

<p><strong>Objective:</strong> The present study has been conducted to investigate the role of plasma homocysteine on neonatal birth weight.</p><p><strong>Methods:</strong> This prospective cross sectional analytical study was conducted in the inpatient department of obstetrics &amp; gynecology, Dhaka Medical College Hospital on 120 term, singleton pregnant women. Pregnant women with plasma total bomocysteine &gt;15 µmol/L were termed as having hyperhomocysteinemia (case, n = 25), while women with plasma total homocysteine ≤15 µmol/L were considered as notmal (control, n = 95). Neonatal birth weight was the main outcome variable which was compared between case and control groups. <strong></strong></p><p><strong>Result:</strong> The entire women in the case group were in their 3rd decades, while 80% of the control group were in this age range and 10% was below 20 and 10% above 30 years old. The cases were older than the controls (25.6 ± 2.0 vs. 23.7 ± 4.7 years, p = 0.051 ). Over three-quarters (76%) of the cases were SSC level educated, while majority (84.2%) of the controls was primary level educated. Eighty percent of the neonates born of mothers with hyperhomocysteinemia were of low birth weight as opposed to only 9.5% in the control group. The mothers of case-group carry nearly 40(95% of CI= 11.5 - 126.4) times higher risk of having low birth weight babies than the mothers with nonnal homocysteine level. The mean birth weight of neonates of case group was observed to be significantly higher (2.8 ± 0.4 kg) than that of control group (2.2 ± 0.4 kg). Correlation between the two variables shows that as plasma homocysteine level of women increases the birth weight of neonates decreases bearing an inverse relationship between these two variables (r = - 0.326, p &lt; 0.001 ). <strong></strong></p><p><strong>Conclusion:</strong> Pregnant women with elevated plasma total homocysteine carry much higher risk of giving low birth weight babies than the women with normal or low level of total homocysteine. Thus, measuring total homcysteine during pregnancy is of much clinical importance as corrective measure could be taken to avert the adverse pregnancy outcome.</p>


2020 ◽  
Vol 10 (2) ◽  
pp. 110-118
Author(s):  
Dewi Dewi Nopitasari ◽  
Tri Tri Maghfiroh

Background of the study : According to data from Indonesia Demographic and Health Survey (IDHS) in 2012, Infant mortality rate (IMR) of 32 deaths / 1,000 live births. The low level of awareness among pregnant women in taking supplements during pregnancy can lead to a variety of impacts for both the mother and baby, including the baby is born with low birth weight (LBW). Objective : Knowing Effect of Supplements On Pregnant Women Against Low Birth Weight Babies in Clinic Pasutri 2018th. Methods : This type of research is an analytical study using cross sectional approach. Respondents in this study were mothers with babies in Clinic Pasutri, the number of 81 respondents. The sampling technique in this study using random sampling techniques. The research instrument was a questionnaire and medical record that is presented in tabular form and processed using SPSS 16.0 type. Result : From 81 respondens obtained maternal pregnancy supplements during pregnancy as many as 53 people or about 65.4% with an incidence rate of low birth weight babies as much as 18 or about 22.2%, while women who did not take supplements of pregnancy by 28 people, or approximately 34.6% LBW incidence rate of about 17 babies, or about 21.0% of total births. Conclusion: There is a relationship effect of supplementation in pregnant women on low birth weight babies in BPS K, Bogor. This is evidenced by the results of P - value is 0.021, which means the value of P - value less than α 0.05.


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