scholarly journals Role of maternal serum homocysteine level on fetal birth weight

2016 ◽  
Vol 6 (2) ◽  
pp. 116
Author(s):  
Afrina Begum ◽  
Joya Sree Roy ◽  
Nilufer Sultana ◽  
Noorjahan Begum

<p><strong>Objective:</strong> The present study has been conducted to investigate the role of plasma homocysteine on neonatal birth weight.</p><p><strong>Methods:</strong> This prospective cross sectional analytical study was conducted in the inpatient department of obstetrics &amp; gynecology, Dhaka Medical College Hospital on 120 term, singleton pregnant women. Pregnant women with plasma total bomocysteine &gt;15 µmol/L were termed as having hyperhomocysteinemia (case, n = 25), while women with plasma total homocysteine ≤15 µmol/L were considered as notmal (control, n = 95). Neonatal birth weight was the main outcome variable which was compared between case and control groups. <strong></strong></p><p><strong>Result:</strong> The entire women in the case group were in their 3rd decades, while 80% of the control group were in this age range and 10% was below 20 and 10% above 30 years old. The cases were older than the controls (25.6 ± 2.0 vs. 23.7 ± 4.7 years, p = 0.051 ). Over three-quarters (76%) of the cases were SSC level educated, while majority (84.2%) of the controls was primary level educated. Eighty percent of the neonates born of mothers with hyperhomocysteinemia were of low birth weight as opposed to only 9.5% in the control group. The mothers of case-group carry nearly 40(95% of CI= 11.5 - 126.4) times higher risk of having low birth weight babies than the mothers with nonnal homocysteine level. The mean birth weight of neonates of case group was observed to be significantly higher (2.8 ± 0.4 kg) than that of control group (2.2 ± 0.4 kg). Correlation between the two variables shows that as plasma homocysteine level of women increases the birth weight of neonates decreases bearing an inverse relationship between these two variables (r = - 0.326, p &lt; 0.001 ). <strong></strong></p><p><strong>Conclusion:</strong> Pregnant women with elevated plasma total homocysteine carry much higher risk of giving low birth weight babies than the women with normal or low level of total homocysteine. Thus, measuring total homcysteine during pregnancy is of much clinical importance as corrective measure could be taken to avert the adverse pregnancy outcome.</p>

2016 ◽  
Vol 32 (1) ◽  
pp. 25
Author(s):  
Edy Marjuang Purba ◽  
Theodola Baning Rahayujati ◽  
Mohammad Hakimi

Teenage pregnancy and low birth weight infants in GunungkidulPurposeThis study aimed to determine any association between teenage pregnancy and low birth weight in Gunungkidul district.MethodThe study used a retrospective cohort design. Samples were 394 people consisting of 197 people in the case group and 197 people in the control group. Case group subjects were teenage pregnant women (<20 years), while control group subjects were adult pregnant women (≥20 years) and both groups delivered a live birth. Case group were taken from all health centers that had complete record and control group were taken using systematic random sampling.ResultsTeenage pregnancy increases the risk of low birth weight babies. Related external factors consist of chronic energy deficiency, anemia and antenatal care visits, while the level of education and hypertension were not related.ConclusionMothers suffering from less chronic energy and anemia increase the risk of giving birth to low birth weight babies, especially in teenage mothers.


2019 ◽  
Vol 27 (1) ◽  
pp. 12
Author(s):  
Kanda Izzatul Aini Ardelia ◽  
Gatut Hardianto ◽  
Djohar Nuswantoro

Objectives: to analyze the relationship between passive smoker of pregnant women with low birth weight (LBW).Materials and Methods: This study is an observational analytic research with case control design, which is LBW as case group and normal birth weight as control group. The location is in Wonokusumo Health Centre, Surabaya, period January 2016 – December 2017. Study sample was 68, consisting of 34 cases and 34 controls. The dependent variable is LBW, while the inde-pendent variable is passive smoking of pregnant women. Sample was excluded multiple births and congenital defects. To determine a significant level, the data collected will be tested with the statistical test Chi-square at significance level ?=0.05.Results: The results showed that a majority (61.5%) of passive smoker of pregnant women are cases. After Chi-square test obtained by value p=0.027 (p?0,05) and OR analysis obtained by 3.04 (CI 95% 1.117 – 8.274), which means there is a relationship between passive smoker of pregnant women with LBW.Conclusion: Passive smoker of pregnant women is relationship with decreased birth weight.


Author(s):  
Julie M. Buser ◽  
Carol J. Boyd ◽  
Cheryl A. Moyer ◽  
Davy Zulu ◽  
Alice Ngoma-Hazemba ◽  
...  

2020 ◽  
Vol 1 (1) ◽  
pp. 16
Author(s):  
Hatijar Hatijar

Low birth weight babies are babies born with a weight less than 2500 grams. LBW (low birth weight) affects the high mortality rate in infants and is at risk of experiencing obstacles in growth and development. LBW is generally caused due to lack of nutrition and nutritional needs from mother to fetus while pregnant women aged less than 20 years and more than 35 years have the risk of giving birth to LBW. The purpose of this study is to determine the risk factors that cause LBW based on maternal age and nutritional status. The research method used was observational with a cross sectional study approach. The sampling technique was random sampling at the Regional Haji Makassar General Hospital in the January to July 2015 period with a total sample of 65 people. Analysis using the Chi Square Test. The results showed that there was a relationship between maternal age, nutritional status of LBW with a value (p value = 0.00 <α = 0.05). Maternal age and nutritional status are factors that influence low birth weight where the results of the study indicate that there is a relationship between maternal age and nutritional status on the incidence of low birth weight. To reduce the incidence of low birth weight, it is necessary to increase counseling about the causes of low birth weight babies by health workers, especially midwives to pregnant women to prevent the risk of low birth weight birth.


2020 ◽  
Vol 11 (3) ◽  
pp. 3396-3401
Author(s):  
Jagadeeswari J ◽  
Swathi D

An infant is the most helpless gathering to get acclimates to the new condition. Following birth, during the initial months, they act as a momentary period during which the baby adjusts from the aquatic to the aerial environment. Nesting positions keeps up the flexion pose as such as intrauterine position and stances. As a fundamental obligation of the nurses, it is one of the most significant nursing procedures, positioning by nesting utilizes a non-pharmacological methodology to diminish torment and push and improve comfort. The present study aims to assess the effectiveness of nesting on posture comfort among low birth weight babies. A quantitative quasiexperimental research design was conducted among 30 low birth weight babies. Convenient sampling technique was used to select samples. A semistructured interview was used to collect demographic data, and posture comfort was assessed using a comfort scale. The babies in the experimental group were placed in a side-lying position inside the nest, which is then rolled blanket. After an hour, the posture comfort was re-assessed. The study results show significant improvement in the posture comfort among the experimental group than the control group after the intervention at the level of p<0.001. This reveals that nesting is highly signiϑicant in the experimental group because it improves posture comfort of the newborn, which in turn promotes growth and development of the low birth weight babies. This indicates that nesting is an effective and secure method to improve posture comfort, maintains the vital signs and helps in the development of low birth weight babies & promotes sound sleep in low birth weight babies.><0.001. This reveals that nesting is highly significant in the experimental group because it improves posture comfort of the newborn, which in turn promotes growth and development of the low birth weight babies. This indicates that nesting is an effective and secure method to improve posture comfort, maintains the vital signs and helps in the development of low birth weight babies & promotes sound sleep in low birth weight babies.


2020 ◽  
Vol 1 (3) ◽  
pp. 58-62
Author(s):  
Mardiaturrahmah Mardiaturrahmah ◽  
Anjarwati Anjarwati

The maternal mortality rate is 19,500 to 20,000 people every year or occurs every 26-27 minutes. The caus of maternal death is bleeding 30.5%, infection 22,5%, gestosis 17,5 and anesthesia 2%.  The infant mortality rate is around 10,000 to 280,000 per 18-20 minutes. The cause of infant mortality is due to Low Birth Weight (LBW) of 15/1000%.  The infant mortality rate in Indonesia is still the highest problem in other ASEAN countries. The infant mortality rate in Indonesia from 2008 was around 248 per 100,000 live births. Basic Health Research (RISKESDA) 2013 shows there are still 10,2% of babies with LBW, which is less than 2,500 grams. Neonatal death because LBW is basically affected by the nutritional status of pregnant women. This study aims to determine the relationship between the nutritional status of pregnant women and the  incidence  of  LBW. This  quantitative  research  uses  a  case  control  approach  using  a  retrospective approach. The population in this study were mothers who had given birth to babies during the last two years (2016-2017). The sampling technique uses total sampling for control cases by using a ratio of 1: 1 for the case group of 40: 40 samples. Analysis using Chi Square with p value 0,000 (OR=3,500, CI 95%=2,313-5,296). There is a relationship between nutritional status of pregnant women and the incidence of LBW. Health Technology Assessment (HTA) which can seek 1000 first day of life can be a breakthrough in assessing and providing interventions of nutrition in families, especially in pregnant women.


2018 ◽  
Vol 5 (2) ◽  
pp. 617
Author(s):  
Malavika P. Santappanavar ◽  
Habeeb U. Khan ◽  
Jaidev M. D. ◽  
Pavan Hegde

Background: More and more women are focusing on obtaining higher education and reaching career objectives. This has in turn, lead to delayed marriage and child birth at a later age. Advanced maternal age at birth has been found to be associated with preterm delivery, low birth weight, intrauterine fetal death and increased perinatal morbidity and mortality. The aim of our study was to know the neonatal outcome in elderly mothers and young mothers, and to compare the neonatal outcome of these two groups. Methods: Present study was a cross sectional, analytical case control study, done in babies delivered to mothers >35 years and <35 years. Information like period of gestation, birth weight, APGAR at 1 minute and 5 minutes, NICU admissions, neonatal outcome like respiratory distress, jaundice, convulsion, etc. were recorded in a proforma. Collected data was analysed using appropriate statistical tests.Results: In the present study, total sample size was 460 (230 cases and 230 controls). Incidence of preterm deliveries, Low birth weight, NICU admissions were significantly more in case group (babies born to mothers >35 years) than the control group (babies born to mothers between 19 to 35 years).Conclusions: It was observed that low birth weight, prematurity and NICU admissions were more common in babies born to elderly mothers.


2018 ◽  
Vol 6 (1) ◽  
Author(s):  
Sri Aminingsih ◽  
Nadiya Istiqomah

Background: Smoking affects blood circulation and makes mothers and babies exposedto hazardous chemicals. Every time a mother smokes, her baby gets less oxygen.Nicotine in cigarettes decreases blood flow to the placenta. At the same time carbonmonoxide (CO) lowers the amount of oxygen carried by blood. In addition, there are toxicchemicals that usually interfere the development of infants (Rahmalia, 2009). Apreliminary study conducted by the author at the Maternity House of Sri Panuntun, PedanKlaten District, there were 30 babies born in August to September 2017, revealed thatthere were 6 babies suffered from low birth weight, while 24 babies have normal birthweight.The purpose: Describing the relationship of pregnant women passive smokers with theincidence of Low Birth Weight was the aim of this study.The subjects : The population in this study was all mothers who gave birth at MaternityMother Sri Panuntun Klaten in January-March 2018 accounted for 55 respondents.The results: The result of this research by using Pearson Chi-Square correlation testobtained p = 0.000.The conclusion: There was a positive correlation between pregnant women who arepassive smokers with the incidence of low birth weight babies.Keywords: Pregnant women, Passive smokers, Low birth weight babies.


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