Pediatric Infectious Diseases Encountered During Wartime Part II: Infectious Diseases Complications in the Individual Pediatric Patient

2021 ◽  
Vol 23 (12) ◽  
Author(s):  
Blake T. Cirks ◽  
Michael Rajnik ◽  
Kathleen B. Madden ◽  
Martin Otollini
Keyword(s):  
Infectious Diseases ◽  
Pediatric Patient ◽  
The Individual

Differentiation of endemic areas by incidence rates of tick-borne infectious diseases as the basis for choosing prevention strategy and tactics

2019 ◽  
pp. 56-61
Author(s):  
N.V. Rudakov ◽  
N.A. Penyevskaya ◽  
D.A. Saveliev ◽  
S.A. Rudakova ◽  
C.V. Shtrek ◽  
...  
Keyword(s):  
High Risk ◽  
Infectious Diseases ◽  
Population Based ◽  
Preventive Therapy ◽  
Incidence Rates ◽  
Prevention Strategy ◽  
Individual Risk ◽  
The Individual ◽  
Integral Assessment ◽  
Very High

Research objective. Differentiation of natural focal areas of Western Siberia by integral incidence rates of tick-borne infectious diseases for determination of the strategy and tactics of their comprehensive prevention. Materials and methods. A retrospective analysis of official statistics for the period 2002-2018 for eight sub-federal units in the context of administrative territories was carried out. The criteria of differentiation were determined by means of three evaluation scales, including long-term mean rates of tick-borne encephalitis, tick-borne borreliosis, and Siberian tick-borne typhus. As a scale gradation tool, we used the number of sample elements between the confidence boundaries of the median. The integral assessment was carried out by the sum of points corresponding to the incidence rates for each of the analyzed infections. Results. The areas of low, medium, above average, high and very high risk of tick-borne infectious diseases were determined. Recommendations on the choice of prevention strategy and tactics were given. In areas of very high and high incidence rates, a combination of population-based and individual prevention strategies is preferable while in other areas a combination of high-risk and individual strategies is recommended. Discussion. Epidemiologic zoning should be the basis of a risk-based approach to determining optimal volumes and directions of preventive measures against natural focal infections. It is necessary to improve the means and methods of determining the individual risk of getting infected and developing tick-borne infectious diseases in case of bites, in view of mixed infection of vectors, as well as methods of post-exposure disease prevention (preventive therapy).

scholarly journals On Immunologists and Microbiologists: Ground Zero in the Battle for Interdisciplinary Knowledge

mBio ◽  
2010 ◽  
Vol 1 (5) ◽  
Author(s):  
Christine A. Biron ◽  
Arturo Casadevall
Keyword(s):  
Infectious Diseases ◽  
Data Acquisition ◽  
Multidisciplinary Research ◽  
Ground Zero ◽  
New Information ◽  
Intellectual Traditions ◽  
Host Pathogen ◽  
Interdisciplinary Knowledge ◽  
The Individual

ABSTRACT The individual disciplines of microbiology and immunology are exploding with new information necessary for understanding host-pathogen relationships, infectious diseases, cancer, and autoimmunity. Because of overlapping scientific interests, immunologists and microbiologists often share common academic affiliations. The coexistence is uneasy. Significant problems arise because the groups have evolved different intellectual traditions. Pressures are intensified by sporadic changes in perceptions of their relative worth. As the mixing of microbiologists and immunologists can be likened to ground zero in the fight for interdisciplinary knowledge, it is useful, at this time of escalating data acquisition and growing appreciation for multidisciplinary research, to examine their histories, the challenges to amalgamation, and the advantages of their association for the advancement of knowledge and the delivery of protection against disease. The exploration supports a recommitment to integration of the disciplines and a proposal to facilitate this by inclusion of expertise bridging the areas.

scholarly journals 1119. Implementation of Pediatric Antimicrobial Stewardship Rounds in a Children’s Hospital

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S397-S398
Author(s):  
Natalie Tucker ◽  
Ezzeldin Saleh ◽  
Marcela Rodriguez
Keyword(s):  
Infectious Diseases ◽  
Antimicrobial Stewardship ◽  
Antibiotic Use ◽  
Antibiotic Consumption ◽  
Antibiotic Prescribing ◽  
Successful Implementation ◽  
Custom Made ◽  
Days Of Therapy ◽  
Before And After ◽  
The Individual

Abstract Background Antimicrobial stewardship programs (ASP) are required in all acute care hospitals per The Joint Commission. ASP must adhere to the recommendations laid out by the Centers for Disease Control and Prevention, but how each ASP chooses to implement these recommendations is left to the individual program. In January 2018, we began formal antimicrobial stewardship (AMS) walking rounds, led by infectious diseases trained physician and pharmacist, in our 99-bed pediatric hospital. Methods In January 2018, we started twice-weekly AMS rounds on the pediatric hospitalist service. A custom-made “Antimicrobial Stewardship Patient List” was designed in our electronic medical record (EMR) to generate a list of all patients receiving antibiotics. The ASP team (comprised of an infectious diseases pharmacist and a pediatric infectious diseases physician) reviewed EMR charts to determine antibiotic prescribing appropriateness and design recommended interventions. Any recommendations and teaching points were then discussed with the hospitalist team in person. After piloting the hospitalist service, AMS rounds were extended to include the general surgery patients and finally the intensive care unit. Data on number of charts reviewed, proposed interventions, and acceptance rates were collected throughout the process. Descriptive statistics were used to assess the intervention data. Results In the first year of the program, 427 patient charts were reviewed with 186 identified interventions. In total, 156 (84.3%) of the interventions were accepted and implemented by the primary team. The most common types of interventions were the duration of therapy (29%), antibiotic discontinuation (16.7%), intravenous to oral conversion (11.3%), de-escalation (10.2%), and infectious diseases consult (5.9%). Conclusion Pediatric AMS rounds led to the successful implementation of the majority of recommended interventions. Future goals of the program include calculating days of therapy per 1000 patient-days to assess antibiotic consumption before and after AMS rounds and to expand into other services to further promote appropriate antibiotic use in hospitalized pediatric patients. Disclosures All authors: No reported disclosures.

scholarly journals A HYBRID MODEL FOR STUDYING SPATIAL ASPECTS OF INFECTIOUS DISEASES

2012 ◽  
Vol 54 (1-2) ◽  
pp. 37-49 ◽  
Author(s):  
BENJAMIN J. BINDER ◽  
JOSHUA V. ROSS ◽  
MATTHEW J. SIMPSON
Keyword(s):  
Infectious Disease ◽  
Spatial Analysis ◽  
Infectious Diseases ◽  
Hybrid Model ◽  
Population Level ◽  
Infectious Agents ◽  
Agent Based ◽  
Individual Level ◽  
The Individual ◽  
Spread Of Infection

AbstractWe consider a hybrid model, created by coupling a continuum and an agent-based model of infectious disease. The framework of the hybrid model provides a mechanism to study the spread of infection at both the individual and population levels. This approach captures the stochastic spatial heterogeneity at the individual level, which is directly related to deterministic population level properties. This facilitates the study of spatial aspects of the epidemic process. A spatial analysis, involving counting the number of infectious agents in equally sized bins, reveals when the spatial domain is nonhomogeneous.

scholarly journals Hepatitis A in Poland in 2016

2019 ◽  
pp. 433-439
Author(s):  
Piotr Polański ◽  
Małgorzata Sadkowska-Todys
Keyword(s):  
Infectious Diseases ◽  
Hepatitis A ◽  
Risk Groups ◽  
Individual Case ◽  
Imported Cases ◽  
The Individual ◽  
Epidemiological Situation

AIM. The aim of this article is to assess the epidemiological situation of Hepatitis A in Poland in 2016 with the regard to the recent years. MATERIALS AND METHODS. The assessment was conducted based on the results of the analysis of data from the bulletins “Infectious diseases and poisonings in Poland in 2016” and “Vaccinations in Poland in 2016”, as well as information from the individual case- questionnaires and reports from epidemiological investigations in outbreaks of hepatitis A, submitted by the sanitary-epidemiological stations to the Department of Epidemiology of Infectious Diseases and Surveillance in NIPH-NIH. RESULTS. In 2016 in Poland there were 35 cases of hepatitis A registered. Incidence per 100 000 inhabitants in the whole country was 0.09, but in different voivodeships varied from 0.03 (in Wielkopolskie voivodeship) to 0.28 (in podkarpackie voivodeship). The incidence among male was slightly higher than women and was 0.11 and 0.08/100 000 respectively. CONCLUSIONS. In 2016 a decrease in the incidence and percentage of imported cases was observed (comparing it to the previous year). Because of the increasing part of population prone to infection good epidemiological situation concerning HAV in Poland paradoxically increases the risk of an occurrence of HAV epidemic, especially in the scope of ongoing large multistate HAV outbreak among MSM. In relation to this situation the enhancement of surveillance over this disease and undertaking anti-epidemic actions gains particular importance, especially when it comes to promoting vaccinations among members of risk groups.

scholarly journals Seroprevalence of markers of transfusiontransmissible diseases in positive blood donors detected in routine screening in the Blood Bank of Hospital Carlos Luis Valverde Vega, Costa Rica. Period 2015 – 2019

2021 ◽  
Vol 9 (4) ◽  
pp. 70-73
Author(s):  
Jean Pablo Castro-Ruiz
Keyword(s):  
Infectious Diseases ◽  
Blood Donors ◽  
Blood Donation ◽  
Individual Characteristics ◽  
Blood Bank ◽  
Health Centers ◽  
Blood Components ◽  
Blood Banks ◽  
Scientific Ethics ◽  
The Individual

Blood is one of the fundamental tissues of our body. Blood donation allows blood banks to meet hospital needs for blood components. Blood transfusion is an activity that carries a risk, originated by a series of causal actions derived from the individual characteristics of donors and patients. Blood components are biological products and as such, they can never be exempt from the risk of transmitting infectious diseases, such as hepatitis B, HIV, syphilis, among others. Thanks to the investigation of the donor database of the Blood Bank of Hospital Dr. Carlos Luis Valverde Vega and the annual statistics of the blood bank, the statistics referring to donations were obtained, according to the type, grade of acceptance and as well as the prevalence of mandatory screening infectious diseases in the blood bank, between the years 2015 and 2019, with the respective authorization of the corresponding scientific ethics committee. This study reported a prevalence for Anti HB Core of 0.99%, 0.14% for HBsAg, 0.11% for syphilis, 0.05% for hepatitis C, 0.02% for HIV and 0% for the disease de Chagas and HTLV I / II. By using the bases of this work, future analyzes with a similar premise may be developed in different blood banks of the different health centers in our country.

scholarly journals Case Report: Rosai-Dorfman Disease Involving Sellar Region in a Pediatric Patient: A Case Report and Systematic Review of Literature

2020 ◽  
Vol 7 ◽  
Author(s):  
Yi Zhang ◽  
Jie Liu ◽  
Jianyu Zhu ◽  
Xiang Zhou ◽  
Kun Zhang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Case Report ◽  
Pediatric Patient ◽  
Cervical Lymphadenopathy ◽  
Sellar Region ◽  
Rosai Dorfman Disease ◽  
The Individual ◽  
Mass Lesions ◽  
Endocrine Abnormality

Rosai-Dorfman disease (RDD) is an extremely rare histiocytic disorder characterized by cervical lymphadenopathy, while the involvement of sellar region is less observed. Here we report a pediatric patient who was initially suspected as sellar germinoma but later identified as RDD. We also conducted a systematic review about RDD involving sellar region. A total of only 14 cases were included and analyzed in our study in terms of clinical presentation, endocrine abnormality, radiological features, pathology, treatment, and follow up. The most common neurological manifestations of sellar RDD is diabetes insipidus and visual changes. Two typical kinds of MRI manifestations were presented in sellar RDD; one is like meningioma-like mass lesions, another showing infiltrative pattern that demonstrates hyperintense areas on T2WI. Currently, the treatment of RDD is tailored to the individual clinical circumstances. For sellar RDD, surgical treatment can be considered to completely remove or debulk the tumor.

scholarly journals 17.E. Workshop: Returning disease prevention and health promotion back to the table: from the 1980ies to the 2050ies

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
◽  
Keyword(s):  
Public Health ◽  
Health Promotion ◽  
Disease Prevention ◽  
Infectious Diseases ◽  
One Health ◽  
Classical Concept ◽  
Healthy Environment ◽  
Prevention And Health Promotion ◽  
The Individual ◽  
And Training

Abstract Disease prevention is part of medical thinking since the time of Hippocrates in the 5th century B.C. However, as a scientific concept, it developed only since the middle of the 19th century through the work of Louis Pasteur and Robert Koch developing and working along with the new germ theory of infectious diseases. Chronic diseases, cardiovascular ones in particular, came into focus only after WW II culminating in the work of Geoffrey Rose and his publication on Sick individuals and sick populations, published 1985. At that time, the new concept of health promotion entered the stage culminating in the Ottawa Charter for Health Promotion, 1986. The classical concepts embrace two basic interrelated modern risk behaviors, sedentary lifestyle and, typically, associated, intake of high caloric food and alcoholic beverages. All of them contribute to obesity diabetes mellitus, elevated blood pressure and cholesterol, often accompanied by smoking as a key risk factor for lung cancer and vascular damage. The individual consequences in terms of reduced quality of life and death due to non-communicable as well as uncontrolled infectious diseases - exemplified by HIV and recently the COVID epidemic - can be considerable and the socioeconomic costs constitute a heavy burden for the population. Whereas research in the field of prevention tries to identify risk factors which may with a certain probability lead to disease, in the field of health promotion efforts are made to find out how to change risky lifestyles, at the individual as well as the community level. Thus, disease prevention and health promotion are two sides of the same coin and should be an essential subject matter for all bachelor or master programs in public health. In this workshop, we shall focus on four questions: 1) What information do we have on modules for disease prevention and targeted health promotion in European Schools of Public Health? 2) What do we know and what should it be? 3) What can we learn from experience in Europe's disadvantaged neighbourhood? 4) How can disease prevention and health promotion contribute to the well-being of humanity in the second half of our century? The last question reaches out beyond the classical concept as a new dimension entered our discourse in the last years which may become the future priority: A healthy environment as a precondition of everything else, in essence in a global dimension: Air, Water, Soil, and Plants, Animals, Humans. Is this - One Health - in the making: A strategy? Leadership? Teaching and training? Solutions do not lay anymore at the individual or community level but require a collective global effort to save our Noah's Ark. Key messages The classical concept of disease prevention and health promotion has lost ground as regards teaching and training at European Schools of Public Health. To strengthen it life-style change is critical. Lifestyle change remains a crucial challenge for prevention and calls for targeted health promotion. The future demands to reach out to the dimension of a healthy environment, the ONE HEALTH concept.

scholarly journals Is It Possible to Prevent Sars-Cov-2 Infection in a Non-Infectious Diseases Ward during the Pandemic on the Example of a Diabetes Clinic Institute of Rural Health, Lublin, Poland?

2021 ◽  
Vol 18 (14) ◽  
pp. 7593
Author(s):  
Piotr Dziemidok ◽  
Daria Gorczyca-Siudak ◽  
Marzena Danielak
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Infectious Diseases ◽  
Rural Health ◽  
21St Century ◽  
World Health ◽  
Diabetes Clinic ◽  
The World ◽  
Patients With Diabetes ◽  
Health Organization ◽  
The Individual

Diabetes is considered an epidemic of the 21st century. On 11 March 2020, two months after the outbreak of COVID-19 (coronavirus disease of 2019) epidemic in China, the World Health Organization announced COVID-19 to be a pandemic. From that time, many hospitals and wards have started to function as both infectious and non-infectious ones; so did the Diabetes Clinic Institute of Rural Health in South-Eastern Poland. Considering the global importance of diabetes and its prevalence worldwide, it seemed important to investigate how the Diabetes Clinic passed through the individual phases of the pandemic, and the possibility of protecting hospitalized patients against future pandemic infection. We present detailed characteristics of the situation in a ward which used to treat non-infectious patients with diabetes only and, nowadays, has been obliged to take into account the risk of spreading SARS-Cov-2 (severe acute respiratory syndrome coronavirus-2) infection also. Moreover, we suggest solutions to avoid cases of infectious diseases in non-infectious wards in the future.

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