Exercise and physical activity in individuals at risk of fracture

Author(s):  
L.M. Giangregorio
Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1357-P
Author(s):  
HEATHER KIMBLEY ◽  
JENNIFER CHADWICK ◽  
CHARLOTTE L. COLEMAN ◽  
MARY A. TULLIER ◽  
LISA D. WOLBERT ◽  
...  

Author(s):  
Ding Ding ◽  
Minna Cheng ◽  
Borja del Pozo Cruz ◽  
Tao Lin ◽  
Shuangyuan Sun ◽  
...  

Abstract Background COVID-19 lockdowns may lead to physical inactivity, a major risk factor for non-communicable diseases. This study aims to determine: 1) the trajectory in daily step counts before, during and after the lockdown in China, and 2) the characteristics associated with the trajectories. Methods From December 2019 to July 2020, smartphone-based step counts were continuously collected in 815 Chinese adults residing in Shanghai over 202 days across three phases: before, during, and after the lockdown. Participant characteristics were reported, and height, weight and body composition measured before the lockdown. A ‘sharp’ regression discontinuity design with cluster robust standard errors was used to test the effect of the lockdown and reopening on daily steps and a linear mixed model was used to examine the characteristics associated with trajectories during the observed period. Results Based on 164,630 person-days of data, we found a sharp decline in daily step counts upon the lockdown (24/01/2020) by an average of 3796 (SE = 88) steps, followed by a significant trend of increase by 34 steps/day (SE = 2.5; p < .001) until the end of the lockdown (22/03/2020). This increasing trend continued into the reopening phase at a slower rate of 5 steps per day (SE = 2.3; p = 0.029). Those who were older, married, university educated, insufficiently active, had an ‘at risk’ body composition, and those in the control group, were slower at recovering step counts during the lockdown, and those who were older, married, without university education and with an ‘at risk’ body composition recovered step counts at a slower pace after the reopening. Conclusions Despite later increases in step counts, COVID-19 lockdown led to a sustained period of reduced physical activity, which may have adverse health implications. Governments and health professionals around the world should continue to encourage and facilitate physical activity during the pandemic.


2014 ◽  
Vol 22 (1) ◽  
pp. 25-33 ◽  
Author(s):  
Kristen M. Beavers ◽  
Fang-Chi Hsu ◽  
Monica C. Serra ◽  
Veronica Yank ◽  
Marco Pahor ◽  
...  

Observational studies show a relationship between elevated serum uric acid (UA) and better physical performance and muscle function. The purpose of this paper was to determine whether regular participation in an exercise intervention, known to improve physical functioning, would result in increased serum UA. For this study, 424 older adults at risk for physical disability were randomized to participate in either a 12-mo moderate-intensity physical activity (PA) or a successful aging (SA) health education intervention. UA was measured at baseline, 6, and 12 mo (n= 368, 341, and 332, respectively). Baseline UA levels were 6.03 ± 1.52 mg/dl and 5.94 ± 1.55 mg/dl in the PA and SA groups, respectively. The adjusted mean UA at month 12 was 4.8% (0.24 mg/dl) higher in the PA compared with the SA group (p= .028). Compared with a health education intervention, a 1-yr PA intervention results in a modest increase in systemic concentration of UA in older adults at risk for mobility disability.


2021 ◽  
pp. 154041532199062
Author(s):  
Elizabeth A. Anderson ◽  
Jane M. Armer

Introduction: Breast cancer-related lymphedema (BCRL) is a treatment sequela with negative physical and psychological implications. BCRL is a lifetime concern for survivors and is currently incurable. With the increase in the Latino population in the United States, it is critical for the cancer care community to address factors that increase BCRL risk and negatively impact long-term quality of life. This literature review undertook to identify successful intervention strategies for BCRL among Latina survivors. Methods: Multiple databases were searched for published articles from 2006 to 2020. PRISMA guidelines were utilized. Data were extracted related to physical activity, diet, and psychosocial stress concerns of Latinas at risk for or living with BCRL. Results: Eleven interventions combined education and skill-building techniques to address physical activity, diet, and stress management for BCRL. Family involvement, peer-mentoring, culturally tailored education, and self-care skill development were identified as important for Latina survivors. Conclusion: Latina survivors may benefit from culturally tailored BCRL education programs and self-management interventions. Health care professionals and researchers should consider cultural influences when developing clinical intervention strategies to enhance outcomes for Latinas at risk for living with BCRL. In addition, including family members and/or peers in such strategies may be helpful to Latina survivors.


2016 ◽  
Vol 90 ◽  
pp. 133-138 ◽  
Author(s):  
Madeleine Bird ◽  
Geetanjali D. Datta ◽  
Andraea van Hulst ◽  
Marie-Soleil Cloutier ◽  
Mélanie Henderson ◽  
...  

2019 ◽  
Vol 6 (1) ◽  
pp. 51-57 ◽  
Author(s):  
Alpha Olivia Hidayati ◽  
Ernawati Hardani

Obesity is a condition of imbalance in the number of calories entered by the number of calories where the excess is heaped up as body fat. Obesity followed by an increase in fat metabolism will cause Reactive Oxygen Species (ROS) production to increase. This condition causes oxidative stress. Indicators of oxidative stress can be observed from plasma levels of Malondialdehyde (MDA). This study aims to determine the risk factors for oxidative stress in obese women. The results of this study indicate that high fat intake (> 60 g / day) is at risk of increasing MDA-P levels twice. Low fiber consumption (<30 gr / day) gives the risk of an increase in MDA-P levels of 2.09 times. Poor physical activity is a risk factor for MDA-P increase of 1.15 times. High cholesterol (> 200mg / l) and LDL (> 130 mg / l) and low HDL (≤45mg / dl) levels are at risk of increasing MDA-P levels by 1.02 times (cholesterol), 1.13 (LDL) ) and 1.12 (HDL). Based on this study it can be concluded that high fat intake, low fiber intake, low physical activity, high cholesterol and HDL levels and low HDL levels are risk factors for oxidative stress.


2016 ◽  
Vol 85 (2) ◽  
pp. 26-28
Author(s):  
Andrew D Hanna ◽  
Natalie V Scime

Global rates of type 2 diabetes (T2D) among children and adolescents are steadily rising. As such, an increasing amount of attention and research has begun to focus on strategies to prevent this chronic and burdensome disease in pediatric populations. The purpose of this article is to briefly review current evidence pertaining to the effectiveness of physical activity versus metformin in improving insulin sensitivity of children at-risk (ie, obese and/or insulin resistant) for developing T2D. Potential barriers to each preventative intervention will also be discussed. Physical activity, both aerobic and resistance, has demonstrated effectiveness in a moderate number of demographically diverse pediatric studies. However, the pediatric population is already alarmingly sedentary with barriers such as lack of motivation, social stigma and discomfort presenting a challenge. A small number of studies have demonstrated the beneficial effects of metformin in children and adolescents for improved insulin sensitivity. However, longer and larger studies are required to confirm these findings and elucidate upon the long-term safety and efficacy of this pharmaceutical in pediatric populations. While no head-to-head studies examining physical activity and metformin exist in pediatric populations and more research is needed, current evidence seems to favour the use of physical activity given the larger quantity of studies and generalizability of its beneficial effects. Thus, physical activity should be emphasized in clinical and public health practice when targeting at-risk children and adolescents to prevent a T2D diagnosis.


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