Effect of an antioxidant functional food beverage on exercise-induced oxidative stress: A long-term and large-scale clinical intervention study

Toxicology ◽  
2010 ◽  
Vol 278 (1) ◽  
pp. 101-111 ◽  
Author(s):  
Maria E. Muñoz ◽  
Ana I. Galan ◽  
Encarna Palacios ◽  
Maria A. Diez ◽  
Begoña Muguerza ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Functional Food ◽  
Large Scale ◽  
Intervention Study ◽  
Clinical Intervention ◽  
Exercise Induced

scholarly journals Argan Oil, Functional Food, and the Sustainable Development of the Argan Forest

2008 ◽  
Vol 3 (2) ◽  
pp. 1934578X0800300 ◽  
Author(s):  
Zoubida Charrouf ◽  
Dominique Guillaume
Keyword(s):  
Functional Food ◽  
Large Scale ◽  
Economic Value ◽  
Developed Countries ◽  
Scale Production ◽  
The Sustainable Development ◽  
Argan Oil ◽  
Large Scale Production ◽  
Argan Tree

For years, in southwestern Morocco, the decline of the argan forest has been accompanied by the concomitant desert encroachment. Preservation of this forest by increasing the economic value of argan tree was proposed twenty years ago, but successful large scale production of certified, high quality argan oil, an edible oil introduced as a functional food, has only been recently achieved. Argan oil is now marketed in most developed countries, despite its elevated price, and protection of the argan forest is now seriously being considered. The aim of this work is to present the recent progress made in argan oil production, the ways explored to commercialize the oil extraction by-products, and recent attempts to use other argan tree parts as part of a long term aim to preserve the argan forest.

Catechins attenuate eccentric exercise-induced inflammation and loss of force production in muscle in senescence-accelerated mice

2011 ◽  
Vol 111 (6) ◽  
pp. 1654-1663 ◽  
Author(s):  
Satoshi Haramizu ◽  
Noriyasu Ota ◽  
Tadashi Hase ◽  
Takatoshi Murase
Keyword(s):  
Oxidative Stress ◽  
Eccentric Exercise ◽  
Inflammatory Mediators ◽  
Reductase Activity ◽  
Force Production ◽  
Monocyte Chemoattractant Protein 1 ◽  
Downhill Running ◽  
Exercise Induced ◽  
Factor Α

Catechins have a great variety of biological actions. We evaluated the potential benefits of catechin ingestion on muscle contractile properties, oxidative stress, and inflammation following downhill running, which is a typical eccentric exercise, in senescence-accelerated prone mice (SAMP). Downhill running (13 m/min for 60 min; 16° decline) induced a greater decrease in the contractile force of soleus muscle and in Ca2+-ATPase activity in SAMP1 compared with the senescence-resistant mice (SAMR1). Moreover, compared with SAMR1, SAMP1 showed greater downhill running-induced increases in plasma CPK and LDH activity, malondialdehyde, and carbonylated protein as markers of oxidative stress; and in protein and mRNA expression levels of the inflammatory mediators such as tumor necrosis factor-α and monocyte chemoattractant protein-1 in muscle. SAMP1 exhibited aging-associated vulnerability to oxidative stress and inflammation in muscle induced by downhill running. Long-term (8 wk) catechin ingestion significantly attenuated the downhill running-induced decrease in muscle force and the increased inflammatory mediators in both plasma and gastrocnemius muscle. Furthermore, catechins significantly inhibited the increase in oxidative stress markers immediately after downhill running, accompanied by an increase in glutathione reductase activity. These findings suggest that long-term catechin ingestion attenuates the aging-associated loss of force production, oxidative stress, and inflammation in muscle after exercise.

scholarly journals Effects of Exercise-Induced ROS on the Pathophysiological Functions of Skeletal Muscle

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Fan Wang ◽  
Xin Wang ◽  
Yiping Liu ◽  
Zhenghong Zhang
Keyword(s):  
Oxidative Stress ◽  
Skeletal Muscle ◽  
Acute Exercise ◽  
Redox System ◽  
The Body ◽  
Muscle Adaptation ◽  
Exercise Induced ◽  
And Function ◽  
Stress Fatigue

Oxidative stress is the imbalance of the redox system in the body, which produces excessive reactive oxygen species, leads to multiple cellular damages, and closely relates to some pathological conditions, such as insulin resistance and inflammation. Meanwhile, exercise as an external stimulus of oxidative stress causes the changes of pathophysiological functions in the tissues and organs, including skeletal muscle. Exercise-induced oxidative stress is considered to have different effects on the structure and function of skeletal muscle. Long-term regular or moderate exercise-induced oxidative stress is closely related to the formation of muscle adaptation, while excessive free radicals produced by strenuous or acute exercise can cause muscle oxidative stress fatigue and damage, which impacts exercise capacity and damages the body’s health. The present review systematically summarizes the relationship between exercise-induced oxidative stress and the adaptions, damage, and fatigue in skeletal muscle, in order to clarify the effects of exercise-induced oxidative stress on the pathophysiological functions of skeletal muscle.

scholarly journals Long Term Supplementation of Lactobacillus plantarum PS128 Attenuated High-Intensity Exercise Induced Acute-Phase Inflammation in Triathletes

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1564-1564
Author(s):  
Hui-Yu Huang ◽  
Shu-Ping Tsao
Keyword(s):  
Oxidative Stress ◽  
Lactobacillus Plantarum ◽  
High Intensity ◽  
Inflammatory Responses ◽  
Science And Technology ◽  
Funding Sources ◽  
Inflammatory Phase ◽  
Exercise Induced ◽  
Biochemical Indices

Abstract Objectives A triathlon, which consists of swimming, bicycling, and running, is a high-intensity and long-term form of exercise that can cause injuries such as muscular damage, inflammation, oxidative stress, and energy imbalance. Previous studies indicated that Lactobacillus supplementation could improve oxidative stress and inflammatory responses. We investigate the effects of Lactobacillus plantarum PS128 supplementation on triathletes for shorten the acute inflammatory phase. Methods The triathletes were assigned to one of two groups with different exercise intensity stimulations with different time-points to investigate the effects of body compositions, inflammation, oxidative stress, performance, and injury-related biochemical indices. Results L.plantarum PS128 supplementation, combined with training, can significantly alleviate oxidative stress (such as creatine kinase, Thioredoxin, and Myeloperoxidase indices) after a triathlon (P < 0.05).This effect is possibly regulated by a 6–13% decrease of indicated pro-inflammation (TNF-α, IL-6, and IL-8) cytokines (P < 0.05) and 55% increase of anti-inflammation (IL-10) cytokines (P < 0.05) after intensive exercise stimulation. Conclusions In conclusion, L. plantarum PS128 may be a potential ergogenic aid for better training management, physiological adaptations to exercise, and health promotion.This study was supported by the Ministry of Science and Technology in Taiwan (grant no. MOST 105- 2410-H-158-008-MY3).This study was supported by the Ministry of Science and Technology in Taiwan (grant no. MOST 105- 2410-H-158-008-MY3). Funding Sources This study was supported by the Ministry of Science and Technology in Taiwan (grant no. MOST 105-2410-H-158-008-MY3).

scholarly journals Diaphragmatic Breathing Reduces Exercise-Induced Oxidative Stress

2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
Daniele Martarelli ◽  
Mario Cocchioni ◽  
Stefania Scuri ◽  
Pierluigi Pompei
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Defense ◽  
Training Session ◽  
Control Group ◽  
Diaphragmatic Breathing ◽  
Stress Levels ◽  
Exercise Induced ◽  
Stress Pathway

Diaphragmatic breathing is relaxing and therapeutic, reduces stress, and is a fundamental procedure of Pranayama Yoga, Zen, transcendental meditation and other meditation practices. Analysis of oxidative stress levels in people who meditate indicated that meditation correlates with lower oxidative stress levels, lower cortisol levels and higher melatonin levels. It is known that cortisol inhibits enzymes responsible for the antioxidant activity of cells and that melatonin is a strong antioxidant; therefore, in this study, we investigated the effects of diaphragmatic breathing on exercise-induced oxidative stress and the putative role of cortisol and melatonin hormones in this stress pathway. We monitored 16 athletes during an exhaustive training session. After the exercise, athletes were divided in two equivalent groups of eight subjects. Subjects of the studied group spent 1 h relaxing performing diaphragmatic breathing and concentrating on their breath in a quiet place. The other eight subjects, representing the control group, spent the same time sitting in an equivalent quite place. Results demonstrate that relaxation induced by diaphragmatic breathing increases the antioxidant defense status in athletes after exhaustive exercise. These effects correlate with the concomitant decrease in cortisol and the increase in melatonin. The consequence is a lower level of oxidative stress, which suggests that an appropriate diaphragmatic breathing could protect athletes from long-term adverse effects of free radicals.

scholarly journals Acute and chronic watercress supplementation attenuates exercise-induced peripheral mononuclear cell DNA damage and lipid peroxidation

2012 ◽  
Vol 109 (2) ◽  
pp. 293-301 ◽  
Author(s):  
Mark C. Fogarty ◽  
Ciara M. Hughes ◽  
George Burke ◽  
John C. Brown ◽  
Gareth W. Davison
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Dna Damage ◽  
Short And Long Term ◽  
Nutritional Compounds ◽  
Exercise Induced ◽  
Randomised Controlled ◽  
Male Subjects ◽  
Antioxidant Effects

Pharmacological antioxidant vitamins have previously been investigated for a prophylactic effect against exercise-induced oxidative stress. However, large doses are often required and may lead to a state of pro-oxidation and oxidative damage. Watercress contains an array of nutritional compounds such as β-carotene and α-tocopherol which may increase protection against exercise-induced oxidative stress. The present randomised controlled investigation was designed to test the hypothesis that acute (consumption 2 h before exercise) and chronic (8 weeks consumption) watercress supplementation can attenuate exercise-induced oxidative stress. A total of ten apparently healthy male subjects (age 23 (sd4) years, stature 179 (sd10) cm and body mass 74 (sd15) kg) were recruited to complete the 8-week chronic watercress intervention period (and then 8 weeks of control, with no ingestion) of the experiment before crossing over in order to compete the single-dose acute phase (with control, no ingestion). Blood samples were taken at baseline (pre-supplementation), at rest (pre-exercise) and following exercise. Each subject completed an incremental exercise test to volitional exhaustion following chronic and acute watercress supplementation or control. The main findings show an exercise-induced increase in DNA damage and lipid peroxidation over both acute and chronic control supplementation phases (P< 0·05v.supplementation), while acute and chronic watercress attenuated DNA damage and lipid peroxidation and decreased H2O2accumulation following exhaustive exercise (P< 0·05v.control). A marked increase in the main lipid-soluble antioxidants (α-tocopherol, γ-tocopherol and xanthophyll) was observed following watercress supplementation (P< 0·05v.control) in both experimental phases. These findings suggest that short- and long-term watercress ingestion has potential antioxidant effects against exercise-induced DNA damage and lipid peroxidation.

scholarly journals Physical Training Status Determines Oxidative Stress and Redox Changes in Response to an Acute Aerobic Exercise

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Farnaz Seifi-skishahr ◽  
Arsalan Damirchi ◽  
Manoochehr Farjaminezhad ◽  
Parvin Babaei
Keyword(s):  
Oxidative Stress ◽  
Exercise Training ◽  
Physical Training ◽  
Redox Balance ◽  
Moderate Intensity ◽  
Training Status ◽  
Reducing Environment ◽  
Exercise Induced ◽  
Male Subjects

Objective. To assess the influence of different physical training status on exercise-induced oxidative stress and changes in cellular redox state.Methods. Thirty male subjects participated in this study and were assigned as well-trained (WT), moderately trained (MT), and untrained (UT) groups. The levels of cortisol, creatine kinase, plasma reduced glutathione to oxidized glutathione (GSH/GSSG), cysteine/cystine (Cys/CySS), and GSH/GSSG ratio in red blood cells (RBCs) were measured immediately and 10 and 30 min after exercise.Results. Following the exercise, plasma GSH/GSSG (p=0.001) and Cys/CySS (p=0.005) were significantly reduced in all groups. Reduction in plasma GSH/GSSG ratio in all groups induced a transient shift in redox balance towards a more oxidizing environment without difference between groups (p=0.860), while RBCs GSH/GSSG showed significant reduction (p=0.003) and elevation (p=0.007) in UT and MT groups, respectively. The highest level of RBCs GSH/GSSG ratio was recorded in MT group, and the lowest one was recorded in the WT group.Conclusion. Long term regular exercise training with moderate intensity shifts redox balance towards more reducing environment, versus intensive exercise training leads to more oxidizing environment and consequently development of related diseases.

Protective effects of long term dietary restriction on swimming exercise-induced oxidative stress in the liver, heart and kidney of rat

2007 ◽  
Vol 25 (2) ◽  
pp. 129-137 ◽  
Author(s):  
Cenk Aydin ◽  
Erdal Ince ◽  
Senay Koparan ◽  
I. Taci Cangul ◽  
Mustafa Naziroglu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Dietary Restriction ◽  
Swimming Exercise ◽  
Protective Effects ◽  
Exercise Induced

Evolution of Large-Scale Coronal Structures

1994 ◽  
Vol 144 ◽  
pp. 29-33
Author(s):  
P. Ambrož
Keyword(s):  
Magnetic Field ◽  
Field Line ◽  
Large Scale ◽  
Coronal Magnetic Field ◽  
Source Surface ◽  
Solar Cycles ◽  
Characteristic Relationship ◽  
The Magnetic Field ◽  
Coronal Structures

AbstractThe large-scale coronal structures observed during the sporadically visible solar eclipses were compared with the numerically extrapolated field-line structures of coronal magnetic field. A characteristic relationship between the observed structures of coronal plasma and the magnetic field line configurations was determined. The long-term evolution of large scale coronal structures inferred from photospheric magnetic observations in the course of 11- and 22-year solar cycles is described.Some known parameters, such as the source surface radius, or coronal rotation rate are discussed and actually interpreted. A relation between the large-scale photospheric magnetic field evolution and the coronal structure rearrangement is demonstrated.

Preventing Long-Term Reading Difficulties through Kindergarten and First Grade Intervention: The Case for Early Intervention

2008 ◽  
Vol 15 (1) ◽  
pp. 22-33 ◽  
Author(s):  
Frank R. Vellutino ◽  
Haiyan Zhang
Keyword(s):  
Early Intervention ◽  
Reading Disability ◽  
Intervention Studies ◽  
Intervention Study ◽  
Reading Difficulties ◽  
First Grade

Abstract This article reviews recent intervention studies that have provided the foundation for a variety of RTI approaches to reading disability classification and remediation. The three-tier model of RTI is defined and discussed. Selected findings from a kindergarten and first grade intervention study are summarized.

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