scholarly journals Obituary: Georges Matheron

2000 ◽  
Vol 32 (4) ◽  
pp. 1190-1192
Author(s):  
Dominique Jeulin
Keyword(s):  
Image Analysis ◽  
Image Coding ◽  
Scientific Community ◽  
Random Media ◽  
Applied Mathematics ◽  
Artificial Vision ◽  
Scientific Heritage ◽  
Wide Range ◽  
Analysis And Synthesis ◽  
Major Figure

The scientific community is saddened to learn of the death of Professor Georges Matheron on 7 August 2000. As a major figure in applied mathematics over four decades, he leaves an outstanding scientific heritage, covering a wide range of domains where probabilistic tools and models are implemented. He also trained more than one generation of researchers, engineers and teachers. In the fields of theoretical and applied random media and image analysis his work has inspired many researchers worldwide: mathematicians, statisticians, physicists, experimentalists, earth scientists, mining engineers and also users of image analysis and synthesis in all its applications (materials, biology, artificial vision, CAD, remote sensing, geophysics, biometry, image coding etc.).

Heterocycle Compounds with Antimicrobial Activity

2020 ◽  
Vol 26 (8) ◽  
pp. 867-904 ◽  
Author(s):  
Maria Fesatidou ◽  
Anthi Petrou ◽  
Geronikaki Athina
Keyword(s):  
Heterocyclic Compounds ◽  
Bacterial Infections ◽  
Scientific Community ◽  
Antimicrobial Agents ◽  
Fungal Infections ◽  
Biological Activities ◽  
Literature Survey ◽  
New Findings ◽  
Wide Range ◽  
Number Of Microorganisms

Background: Bacterial infections are a growing problem worldwide causing morbidity and mortality mainly in developing countries. Moreover, the increased number of microorganisms, developing multiple resistances to known drugs, due to abuse of antibiotics, is another serious problem. This problem becomes more serious for immunocompromised patients and those who are often disposed to opportunistic fungal infections. Objective: The objective of this manuscript is to give an overview of new findings in the field of antimicrobial agents among five-membered heterocyclic compounds. These heterocyclic compounds especially five-membered attracted the interest of the scientific community not only for their occurrence in nature but also due to their wide range of biological activities. Method: To reach our goal, a literature survey that covers the last decade was performed. Results: As a result, recent data on the biological activity of thiazole, thiazolidinone, benzothiazole and thiadiazole derivatives are mentioned. Conclusion: It should be mentioned that despite the progress in the development of new antimicrobial agents, there is still room for new findings. Thus, research still continues.

A Comprehensive Review on C-3 Functionalization of β-Lactams

2019 ◽  
Vol 16 (1) ◽  
pp. 3-16 ◽  
Author(s):  
Reshma Nagpal ◽  
Jitender Bhalla ◽  
Shamsher S. Bari
Keyword(s):  
Scientific Community ◽  
Organometallic Reagent ◽  
Reaction Conditions ◽  
Biological Potential ◽  
Wide Range ◽  
Economic Strategies ◽  
Synthetic Utility ◽  
Recent Advancement ◽  
Equivalent Method ◽  
Made In

Background:A lot of advancement has been made in the area of β-lactams in recent times. Most of the research is targeted towards the synthesis of novel β-lactams, their functionalization and exploring their biological potential. The C-3 functionalization of β-lactams has continued to attract considerable interest of the scientific community due to their utility as versatile intermediates in organic synthesis and their therapeutic applications. This has led to the significant increase in efforts towards developing efficient and economic strategies for C-3 functionalized β-lactams.Objective:The present review aims to highlight recent advancement made in C-3 functionalization of β-lactams.Conclusion:To summarize, functionalization of β-lactams at C-3 is an essential aspect of β-lactam chemistry in order to improve/modify its synthetic utility as well as biological potential. The C-3 carbocation equivalent method has emerged as an important and convenient strategy for C-3 functionalization of β-lactam heterocycles which provides a wide range of β-lactams viz. 3-alkylated β-lactams, 3-aryl/heteroarylated β-lactams, 3- alkoxylated β-lactams. On the other hand, base mediated functionalization of β-lactams via carbanion intermediate is another useful approach but their scope is limited by the requirement of stringent reaction conditions. In addition to this, organometallic reagent mediated α-alkylation of 3-halo/3-keto-β-lactams also emerged as interesting methods for the synthesis of functionalized β-lactams having good yields and diastereoselectivities.

scholarly journals Image Segmentation and Object-Based Image Analysis for Environmental Monitoring: Recent Areas of Interest, Researchers’ Views on the Future Priorities

2020 ◽  
Vol 12 (11) ◽  
pp. 1772
Author(s):  
Brian Alan Johnson ◽  
Lei Ma
Keyword(s):  
Remote Sensing ◽  
Image Analysis ◽  
Image Segmentation ◽  
Online Survey ◽  
Accuracy Assessment ◽  
Learning Approaches ◽  
Special Issue ◽  
Object Based Image Analysis ◽  
Object Based ◽  
Wide Range

Image segmentation and geographic object-based image analysis (GEOBIA) were proposed around the turn of the century as a means to analyze high-spatial-resolution remote sensing images. Since then, object-based approaches have been used to analyze a wide range of images for numerous applications. In this Editorial, we present some highlights of image segmentation and GEOBIA research from the last two years (2018–2019), including a Special Issue published in the journal Remote Sensing. As a final contribution of this special issue, we have shared the views of 45 other researchers (corresponding authors of published papers on GEOBIA in 2018–2019) on the current state and future priorities of this field, gathered through an online survey. Most researchers surveyed acknowledged that image segmentation/GEOBIA approaches have achieved a high level of maturity, although the need for more free user-friendly software and tools, further automation, better integration with new machine-learning approaches (including deep learning), and more suitable accuracy assessment methods was frequently pointed out.

scholarly journals REVIEW: INTEGRATIVE COORDINATION ABILITIES OF COACHES IN WELLNESS TYPES OF GYMNASTICS

2015 ◽  
Vol 4 (99) ◽  
pp. 2-7
Author(s):  
Olga Aftimichuk
Keyword(s):  
Professional Training ◽  
Theoretical Research ◽  
Professional Activity ◽  
Human Organism ◽  
Wide Range ◽  
Different Types ◽  
Analysis And Synthesis ◽  
And Behavior ◽  
Coordination Development ◽  
Complex Coordination

Background. The coordination development level influences the execution of any human activity, which is very important for the general perception of this activity and behavior in general. It is especially relevant for to coaches in wellness and sports gymnastics. The aim of the present study was the identification of the coordination skills of coaches of different types of gymnastics, which would improve the process of their professional training. Material and Methods. This review presents a synthesis of research conducted by the author. The following methods of theoretical research were used: abstract and axiomatic methods, analysis and synthesis, induction and deduction, idealization, comparison and generalization, and projecting. Results. The coaches’ training in different types of gymnastics includes the development of a wide range of professional skills: the tandem of communicative and motor skills that determine one type of complex coordination. The realization of complex coordination presupposes the participation of sensor systems (analyzer systems), which are visual, auditory, tactile, vestibular, and motor systems. The basic speech component of complex coordination in coaches’ activity/behavior determines his/her communicative orientation in the process of teaching. It is explained by the connection between the cultivation of complex coordination skills with the congenital and genetic, anatomical and physiological particularities of the human organism. We determined the coordination abilities, the formation of which contributes to the development of complex coordination skills. Conclusion. Development of integrative coordination abilities is an important part of professional activity of coaches of gymnastics, which requires such preparation.

scholarly journals Originals of operating images for generalized problems of unsteady heat conductivity

2019 ◽  
Vol 14 (4) ◽  
pp. 77-86 ◽  
Author(s):  
E. M. Kartashov
Keyword(s):  
Mathematical Models ◽  
Bessel Functions ◽  
Applied Mathematics ◽  
Operational Calculus ◽  
Polymeric Materials ◽  
Thermal Reaction ◽  
Heaviside Step Function ◽  
External Influences ◽  
Wide Range ◽  
Variable Function

A series of operating (Laplace) non-standard images, the originals of which are absent in well-known reference books on operational calculus, are considered. By reducing one of the basic images to the Riemann-Mellin contour integral for the modified Bessel functions and analyzing the corresponding inversion formula using the approaches of the complex variable function theory, an analytical form of the original original is found, which is abrupt in nature with a break point. It is shown that analytical solutions of the corresponding mathematical models using the found originals have a wave character, which is expressed by the presence of the Heaviside step function in the solutions. The latter means that at any time there is a region of physical disturbance to the point of discontinuity and an unperturbed area after the point of discontinuity. The images studied are included in the operational solutions of mathematical models in many areas of applied mathematics. physics, thermomechanics, thermal physics, in particular in the theory of thermal shock of viscoelastic bodies, in the study of the thermal reaction of solids based on the classical Maxwell-Cattaneo-Lykov-Vernott phenomenology, taking into account the final rate of heat propagation. These models are needed to study the thermal reaction of relatively new consolidated structurally sensitive polymeric materials in structures exposed to high-intensity external influences. The analytical relations obtained for the originals and the original improper integrals resulting from them, containing combinations of Bessel functions, can be used in the general methodology of constructing and applying various mathematical models in a wide range of external influences on materials in many fields of science and technology.

scholarly journals Systemic Puppet Therapy in Rehabilitation Practice

2020 ◽  
Vol 99 (5) ◽  
pp. 88-93
Author(s):  
O.A. Lanberg ◽  
L.G. Khayet ◽  
T.V. Kadinskaya
Keyword(s):  
Research Centre ◽  
Face To Face ◽  
National Medical ◽  
Resource Search ◽  
Wide Range ◽  
Analysis And Synthesis ◽  
Scope Of Application ◽  
Puppet Therapy ◽  
Psychological Assistance ◽  
Intellectual Level

The concept of systemic puppet therapy proposed by the authors is described. Therapeutic work with puppets is a promising method of psychological assistance as part of rehabilitation processes. Its insufficient use is due to its low structurality. The phased application of morphological analysis and synthesis made it possible to streamline the known and develop new effective methods of puppet therapy. The proposed systemic puppet therapy is an ordered polymodal set of static (lining on the table or on the floor of a puppet arranged set) and dynamic (presenting history on behalf of the puppet or staging a performance) methods, individual and group methods, face-to-face and remote forms of work, algorithms for their choice.The size, material and design of puppets, quantitative and qualitative composition of their therapeutic set are justified. Methods of puppet therapy of different degree of structuring and depth of exposure for patients with different level of intelligence are described, including category and scope of application of the technique, instructions to the patient, plan of results discussion,transformation procedure providing therapeutic effect. Implementing a polymodal approach, after working with puppets, patients painted, composed and analysed works of literature andart. The field of puppet therapy intersected with the fields of drama-, mask- and art therapy, body-oriented and verbal therapy, psychodrama and system arrangements. Puppet therapy content included work with feelings and emotions, with the process of communication and social roles, with verbal and non-verbal diagnostics and self-diagnostics, with personal features and a system of relationships,with values and needs, with existential problems of patients. Systemic puppet therapy is applicable to a wide range of nosological categories, therapeutic situations, physical condition, intellectual level, gender and age characteristics of patients.The conditions and examples of application of techniques in the National Medical Research Centre of Rehabilitation and Balneology with the tasks of correcting unproductive attitudes and the system of patient relations, correcting perceptions of oneself; capacity-building and resource search; development of a compliance installation and active participation in rehabilitation are given.

Alfred Russel Wallace (1823–1913): evolution and medicine

2009 ◽  
Vol 17 (4) ◽  
pp. 214-216
Author(s):  
Henry P O'Connell
Keyword(s):  
Scientific Community ◽  
Charles Darwin ◽  
Linnean Society ◽  
Alfred Russel Wallace ◽  
Scientific World ◽  
Wide Range ◽  
Evolution And Medicine

The theory we now know simply as ‘evolution’ was first presented to the scientific world one and a half centuries ago, on 1 July 1858, when the work of two men, Alfred Russel Wallace and Charles Robert Darwin (1809–82), was jointly read at the Linnean Society. While Charles Darwin has rightly taken his place in history as one of the greatest scientists of all time, Alfred Russel Wallace has been largely forgotten outside of the scientific community. However, Wallace was a prolific researcher and writer with interests in a wide range of topics, from medicine to economics.

Snacking Around the World

2017 ◽  
pp. 91-130
Keyword(s):  
Social Media ◽  
Image Analysis ◽  
Image Coding ◽  
Empirical Data ◽  
Theoretical Approaches ◽  
The World ◽  
Social Media Platforms ◽  
Image Set ◽  
Research Questions ◽  
Biasing Effects

Social media platforms enable access to large image sets for research, but there are few if any non-theoretical approaches to image analysis, categorization, and coding. Based on two image sets labeled by the #snack hashtag (on Instagram), a systematic and open inductive approach to identifying conceptual image categories was developed, and unique research questions designed. By systematically categorizing imagery in a bottom-up way, researchers may (1) describe and assess the image set contents and categorize them in multiple ways independent of a theoretical framework (and its potential biasing effects); (2) conceptualize what may be knowable from the image set by the defining of research questions that may be addressed in the empirical data; (3) categorize the available imagery broadly and in multiple ways as a precursor step to further exploration (e.g., research design, image coding, and development of a research codebook). This work informs the exploration and analysis of mobile-created contents for open learning.

scholarly journals Computer-aided prediction and design of IL-6 inducing peptides: IL-6 plays a crucial role in COVID-19

2020 ◽  
Author(s):  
Anjali Dhall ◽  
Sumeet Patiyal ◽  
Neelam Sharma ◽  
Salman Sadullah Usmani ◽  
Gajendra P S Raghava
Keyword(s):  
Scientific Community ◽  
Prediction Models ◽  
Vital Role ◽  
Machine Learning Techniques ◽  
Validation Dataset ◽  
Independent Validation ◽  
Immune Epitope ◽  
Learning Techniques ◽  
Wide Range ◽  
Immune Epitope Database

Abstract Interleukin 6 (IL-6) is a pro-inflammatory cytokine that stimulates acute phase responses, hematopoiesis and specific immune reactions. Recently, it was found that the IL-6 plays a vital role in the progression of COVID-19, which is responsible for the high mortality rate. In order to facilitate the scientific community to fight against COVID-19, we have developed a method for predicting IL-6 inducing peptides/epitopes. The models were trained and tested on experimentally validated 365 IL-6 inducing and 2991 non-inducing peptides extracted from the immune epitope database. Initially, 9149 features of each peptide were computed using Pfeature, which were reduced to 186 features using the SVC-L1 technique. These features were ranked based on their classification ability, and the top 10 features were used for developing prediction models. A wide range of machine learning techniques has been deployed to develop models. Random Forest-based model achieves a maximum AUROC of 0.84 and 0.83 on training and independent validation dataset, respectively. We have also identified IL-6 inducing peptides in different proteins of SARS-CoV-2, using our best models to design vaccine against COVID-19. A web server named as IL-6Pred and a standalone package has been developed for predicting, designing and screening of IL-6 inducing peptides (https://webs.iiitd.edu.in/raghava/il6pred/).

Sign in / Sign up

Export Citation Format

Share Document