Calcium metabolism of cows at parturition and during milk production

1969 ◽  
Vol 72 (3) ◽  
pp. 455-458 ◽  
Author(s):  
B. F. Sansom

SUMMARYCalcium metabolism in dairy cows has been studied at three periods, namely 2 weeks before and 2 weeks after parturition, and also at peak lactation. Of the four parameters studied—percentage absorption from the diet, endogenous excretion, exchangeable pool size and bone accretion rate—only the last showed significant changes, falling at parturition and rising to pre-calving levels subsequently. There was no increase in the percentage absorption of calcium from the diet after calving but total calcium absorption rose because of increased dietary intake.

2001 ◽  
Vol 26 (1) ◽  
pp. 147-159 ◽  
Author(s):  
D. O'Callaghan ◽  
J.M. Lozano ◽  
J. Fahey ◽  
V. Gath ◽  
S. Snijders ◽  
...  

AbstractThe reduced fertility that is becoming more evident in high yielding dairy cows may be related to many factors including changes in milk production, food intake and fluctuations in body condition. Metabolic and production markers have been studied as a way of predicting success to a particular artificial insemination. Successful conception to a particular service was not associated with milk production, body condition or plasma concentrations of several indicators of metabolic state around the time if insemination. This highlights the importance of time of information collection in fertility management programmes. Increased food intake may reduce systemic progesterone concentrations. This is more evident in sheep than cattle, but a positive relationship between systemic progesterone early post mating and establishment of pregnancy in cattle has been reported. However, progesterone concentrations in the ovarian vein and endometrium are not strongly correlated with systemic progesterone. Thus, the significance of modest changes in systemic progesterone in affecting oocyte and embryo development must be questioned. Blood urea concentrations can be altered by diet, and reduced pregnancy rates have been reported in cows with high urea concentrations. However, in other recent studies, no difference was reported in serum urea in cows that conceived and those that failed to conceive. Pregnancy rate was equally high in heifers when in-vitro produced embryos were transferred to heifers on high and low urea diets. When embryos were produced in sheep on high and low dietary urea, the effects on embryo development appear to occur early in the developmental process, suggesting a substantial effect on the development of the oocyte. The developmental capacity of oocytes and quality of embryos is reduced in cattle maintained on extremely high dietary intakes. Oocyte developmental capacity is reduced in cows of higher genetic merit and embryo quality can be substantially reduced in the early postpartum period. Collectively, these results suggest that high dietary intake or high metabolic load is deleterious to normal oocyte development and establishment of pregnancy. This highlights the importance of further studies on the effect of dietary intake on metabolic state and follicle, oocyte and embryo development. In a practical context, these results highlight the importance of nutritional management and avoiding changes in the amount or type of diet around the time of mating in high-production dairy cows.


2017 ◽  
Vol 5 ◽  
Author(s):  
David Whyte ◽  
Kuldeep Sharma ◽  
Paul Tarver

SummaryAn Aloe vera and manuka honey commercial supplement (Cow and Calf Formula, DairyCare Ltd, NZ) was fed to approximately 40% of a commercial New Zealand herd with over 1000 cows in lactation following spring calving (August) until the end of lactation (April the following year). The 5 ml of supplement was added automatically to the feed for the treatment group via transponder identification units during at milking. At peak lactation (until October) there was a 5.5% increase (11.76 versus 12.41 litres per milking for control and treated cows respectively; P < 0.001) in yield for the supplemented cows, and over the whole season there was a 4.7% milk yield increase (8.12 versus 8.50 litres per milking for control and treated cows respectively). Data from December and January (high summer) showed no significant increase in milk yield, which was due to a major drought in the area and loss of grazed forage intakes. From these results, it was considered that that the Aloe vera and manuka honey, acting either separately or in synergy, resulted in more nutrients being available for milk production.


2020 ◽  
Vol 8 (2) ◽  
pp. 79-84
Author(s):  
Ali Mahmud ◽  
Woro Busono ◽  
Puguh Surjowardojo ◽  
Yuli Arif Tribudi

This research was conducted in PT Greenfields Indonesia, Babadan Village, Ngajum Districts, Malang, East Java. The purpose of the study was to compare the milk production of FH (Friesian Holstein) dairy cows in various lactation periods. The material used in this research was data records of Australian FH, which have been developed in the Greenfields Indonesia farm. The data used were from 473 dairy cows, which consisted of 100 heads for each lactation period from the period I up to period IV and 73 heads for lactation period V. The variables measured were milk production 305 day 2X ME, daily milk yield production, peak day production, and the peak lactation. The data were analyzed using analysis of variance, and if the result showed differences, the analysis was continued using the Duncan test. The results showed that the increase in the lactation period significantly (P<0.01) decreased milk production and increased the duration of lactation peaks of FH cows. The highest milk production 305 day 2X ME was in the lactation period II, which was around 10232.90 ± 1036.62 kg/lactation or 32 ± 5.13 kg/day. In this period, the peak day in milk lactation was 71.5 ± 27.5 days, and the peak of milk production was 45.7 ± 4.1 kg/day. In conclusion, milk production increased from the first lactation period to the second lactation period and then decreased in subsequent periods. The peak of the first lactation period was reached longer, then falls in the second lactation period and then increases again at the following lactation period


2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Joanna Hodges ◽  
Meryl Wastney ◽  
Emily Hohman ◽  
Connie Weaver

Abstract Objectives Quantifying the long-term effects of nutritional or drug treatments on bone is challenging due to the delay in time between treatment and changes in bone mass. The objective of this study was to develop a dynamic (non-steady state) mathematical model of calcium metabolism in young growing rats as an analogue for human adolescents and to use that model to predict the effects of treatments on calcium mass in bone. Methods A dynamic model of calcium metabolism was developed using kinetic data collected from Sprague-Dawley male rats (n = 54) dosed intraperitoneally with 50 μCi of 45Ca at 4 wk of age. Total calcium and 45Ca levels measured in serum and 24-h urine samples collected periodically for 45 d after treatment were analyzed by compartmental modeling using WinSAAM software. Concurrently, tracer (45Ca) and tracee (total calcium) models, together called the ‘dynamic model’, were developed. Growth of the rats was modeled using a formula based on body weight. Calcium absorption was decreased by about 50% at wk 6 to account for the reduction in bone mineral accretion in late puberty. During the first 40 d after weaning, the model included a 4-fold decrease in bone resorption and a 20-fold decrease in bone formation, consistent with previous findings of studies conducted in growing rats. Data were fitted by iterative least squares regression analysis. To mimic the effects of dietary and drug interventions during adolescence, the absorption efficiency was manipulated in terms of degree, timing, and duration and the subsequent changes in bone mass were quantified. Results The dynamic model predicted that, if absorption decreased by 25% instead of 50% during growth, the rate of bone accretion would be 32% higher and the bone mineral mass at d 50 would be 24% larger, suggesting that a dietary or drug intervention that minimizes the drop in absorption, would result in a higher bone mineral mass. Conclusions A dynamic model of calcium metabolism during growth was developed and used to predict the effect of interventions on bone mass. These predictions would be tested in future studies. Funding Sources Purdue University Graduate School and Amgen, Inc., Thousand Oaks, CA.


1998 ◽  
Vol 76 (2) ◽  
pp. 218-228 ◽  
Author(s):  
Sutada Lotinun ◽  
Liangchai Limlomwongse ◽  
Nateetip Krishnamra

Since a pharmacological dose of prolactin has previously been reported to enhance calcium absorption and bone calcium turnover, the role of endogenous prolactin in the regulation of calcium metabolism was investigated in the balance studies of Wistar rats between days 17 and 20 of first (P1) and fourth (P4) pregnancy and between days 12 and 15 of lactation (L). Each group was divided into 3 subgroups: one subgroup was given 0.9% NaCl (control); one was given 0.3 mg bromocriptine/100 g body weight ip twice daily for 3 days (to suppress prolactin secretion); and one was given bromocriptine and 0.25 mg prolactin/100 g body weight sc daily for 3 days. All three groups received 1 mL/100 g body weight of 1.25 mM calcium gluconate containing 2 mCi (1 Ci = 37 GBq) 45Ca daily for 3 days. Compared with the two pregnant controls, the L group had higher food consumption and higher fecal calcium excretion and lower urinary calcium excretion (% intake). Bromocriptine administration increased total calcium excretion from 59% intake to 84 and 66% intake in P1 and P4, respectively, suggesting that endogenous prolactin decreased total calcium excretion. On the other hand, exogenous prolactin had no effect on the calcium balance of P1 but increased the total calcium excretion in P4 from 57 to 66% intake. In contrast, the calcium balance of lactating rats was not altered by suppression of endogenous prolactin secretion or exogenous prolactin. Considering bone 45Ca content as representing bone Ca turnover, a lower value of bone 45Ca content indicated an accelerated bone Ca turnover. It was found that bromocriptine had no effect in P1 but decreased bone Ca turnover rate in the P4 and L groups, indicating an accelerating effect of endogenous prolactin on bone Ca turnover in the P4 and L groups. Exogenous prolactin, on the other hand, decreased bone Ca turnover rate in every group. Muscle Ca turnover was affected by bromocriptine and exogenous prolactin in the same manner as bone 45Ca contents. Interestingly, the biphasic action of prolactin was demonstrated in both calcium absorption and bone calcium turnover. It could be concluded that during pregnancy and lactation, endogenous prolactin increases food consumption, fractional calcium absorption, and bone calcium turnover, apparently to increase calcium availability for fetal development and milk calcium secretion.Key words: bone turnover, bromocriptine, calcium absorption, calcium excretion, calcium retention, prolactin.


Animals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1959
Author(s):  
Jolanta Różańska-Zawieja ◽  
Stanisław Winnicki ◽  
Joanna Zyprych-Walczak ◽  
Alicja Szabelska-Beręsewicz ◽  
Idzi Siatkowski ◽  
...  

The study attempted to estimate the lactation curves of primiparous dairy cows in relation to their feeding management. Therefore, the first aim of the study was to determine and compare the lactation curves of primiparous dairy cows using Wood’s model and to estimate the association between the lactation curves and feeding management. The second objective was to investigate the effect of the culling rate on improvement in the milk yield of primiparous dairy herds. The study was conducted on four commercial dairy farms of Polish Holstein–Friesian cows using different feeding systems (TMR—total mixed ration and PMR—partial mixed ration) and management (T1—one TMR throughout lactation; P1—one PMR throughout lactation; T2 and T3—three feed periods such as FRESH, TMR I and TMR II according to days in milk). The data used for the study were obtained from monthly milk performance evaluations of 1662 primiparous cows conducted by the Polish Federation of Cattle Breeding and Dairy Farmers throughout the year 2015. Wood’s lactation model was used to plot curves for milk yield, fat and protein content, lactose content, and milk urea contents. The highest milk yield for the whole lactation and in the peak lactation phase was recorded for cows in herd T1. This herd reached peak lactation on day 105 of milking, with an average milk yield of 42.1 kg, which was about 5 kg more milk than in the other herds. The study showed that the culling of primiparous cows in herd T1 after 30, 60 and 90 days of lactation prevented a significant reduction in milk yield in a 305-day lactation. It also increased average milk production by 1586.9 kg per primiparous dairy cow.


2013 ◽  
Vol 41 (05) ◽  
pp. 289-296 ◽  
Author(s):  
K. Seyrek-Intas ◽  
K. Failing ◽  
G. Yilmazbas Mecitoglu ◽  
H. Bostedt ◽  
D. Seyrek-Intas

Summary Objective: To determine the intravascular electrolyte status in dairy cows with respect to age and different courses of parturition to clarify etiological factors influencing peri- or intrapartal imbalances of electrolyte homeostasis. Material and methods: A total of 64 cows at birth were evaluated (primiparous n = 34, pluriparous n = 30). Thirty-three cows showed normal delivery, while 31 cows had a complicated birth. Blood samples were collected intra partum (i. p.) and 2, 4, 6, 8, 12, 16, 24 h post partum (p. p.) as well as [2, 3, 4, 5, 7, 10 days p. p. and levels of total calcium (Catotal), ionized calcium (Caion), inorganic phosphate (Pa), Mg, Na, K, Cl were determined. Results: The results revealed that electrolytes show great fluctuation during and immediately p. p. in relation to age. Already during parturition pluriparous cows had a lower Catotal and Pa concentration compared to primiparous animals. Cows with dystocia exhibited a more intensive and longer lasting decrease of Ca compared to cows with normal birth. In relation to age and severity of birth Pa concentration showed a differing but basically typical course for this electrolyte. Mg, Na, K and Cl concentrations were higher during and immediately after birth compared to p. p. values. Until day 10 p. p. these electrolyte concentrations declined more in older cows with dystocia compared to younger animals. However, the influence of dystocia on concentration of these electrolytes was milder in contrast to Ca and Pa. Conclusions: In summary, primarily older cows are predisposed to imbalances of electrolyte homeostasis intra partum and at the beginning of the lactation. These changes are potentiated in case of complications during parturition. Intravascular Catotal, Caion as well as Pa are most severely affected. Clinical relevance: These results may constitute the basis for a comprehensive metaphylaxis during the peripartal period, especially in cows after dystocia, to positively influence the early convalescence phase.


Author(s):  
N.A. Thomson

In a four year grazing trial with dairy cows the application of 5000 kg lime/ ha (applied in two applications of 2500 kg/ha in winter of the first two years) significantly increased annual pasture production in two of the four years and dairy production in one year. In three of the four years lime significantly increased pasture growth over summer/autumn with concurrent increases in milk production. In the last year of the trial lime had little effect on pasture growth but a relatively large increase in milkfat production resulted. A higher incidence of grass staggers was recorded on the limed farmlets in spring for each of the four years. In the second spring immediately following the second application of lime significant depressions in both pasture and plasma magnesium levels were recorded. By the third spring differences in plasma magnesium levels were negligible but small depressions in herbage magnesium resulting from lime continued to the end of the trial. Lime significantly raised soil pH, Ca and Mg levels but had no effect on either soil K or P. As pH levels of the unlimed paddocks were low (5.2-5.4) in each autumn and soil moisture levels were increased by liming, these factors may suggest possible causes for the seasonality of the pasture response to lime


Author(s):  
Zinaida Fedorova ◽  
Yuri Tkachenko ◽  
Vasily Bliadze

The data on feeding dairy cows of an energy protein concentrate (EPC) are presented. EPC consists of grain of narrow-leaved lupine, flax, triticale, subjected to heat treatment on a press extruder. The effect of EPC on the change in milk production of cows was determined. The inclusion of extruded concentrate based on lupine grains in the diets of cows made it possible to obtain an increase in milk. Concentrate based on lupine, flax, triticale is equal in biological value to full-fat soy, and at a much lower cost.


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