scholarly journals Age, time and cohort factors in mortality from cancer of the cervix

1973 ◽  
Vol 71 (2) ◽  
pp. 253-259 ◽  
Author(s):  
J. C. Barrett
Keyword(s):  
Age Groups ◽  
Mortality Rates ◽  
Age Group ◽  
Mortality Pattern ◽  
England And Wales ◽  
Cancer Of The Cervix

SUMMARYData for mortality from cancer of the cervix in England and Wales by 5-year age groups and four quinquennia (1951–70) are analysed. The logarithms of the mortality rates are regressed on age group, epoch of death and epoch of birth. The factors obtained are considered in relation to particular features of the mortality pattern, such as the reversal of trend in certain age groups.

scholarly journals Excess mortality in England and Wales during the first wave of the COVID-19 pandemic

2020 ◽  
Author(s):  
Evangelos Kontopantelis ◽  
Mamas A Mamas ◽  
John Deanfield ◽  
Miqdad Asaria ◽  
Tim Doran
Keyword(s):  
Excess Mortality ◽  
Age Groups ◽  
Mortality Rates ◽  
Mortality Data ◽  
List Type ◽  
Age Group ◽  
The West ◽  
England And Wales ◽  
West Midlands ◽  
Excess Deaths

AbstractBackgroundDeaths during the COVID-19 pandemic result directly from infection and exacerbation of other diseases and indirectly from deferment of care for other conditions, and are socially and geographically patterned. We quantified excess mortality in regions of England and Wales during the pandemic, for all causes and for non-COVID-19 associated deaths.MethodsWeekly mortality data for 1 Jan 2010 to 1 May 2020 for England and Wales were obtained from the Office of National Statistics. Mean-dispersion negative binomial regressions were used to model death counts based on pre-pandemic trends and exponentiated linear predictions were subtracted from: i) all-cause deaths; and ii) all-cause deaths minus COVID-19 related deaths for the pandemic period (07-13 March to 25 April to 8 May).FindingsBetween 7 March and 8 May 2020, there were 47,243 (95%CI: 46,671 to 47,815) excess deaths in England and Wales, of which 9,948 (95%CI: 9,376 to 10,520) were not associated with COVID-19. Overall excess mortality rates varied from 49 per 100,000 (95%CI: 49 to 50) in the South West to 102 per 100,000 (95%CI: 102 to 103) in London. Non-COVID-19 associated excess mortality rates ranged from −1 per 100,000 (95%CI: −1 to 0) in Wales (i.e. mortality rates were no higher than expected) to 26 per 100,000 (95%CI: 25 to 26) in the West Midlands.InterpretationThe COVID-19 pandemic has had markedly different impacts on the regions of England and Wales, both for deaths directly attributable to COVID-19 infection and for deaths resulting from the national public health response.FundingNoneSummary boxWhat is already known on the subjectThe number of deaths due to COVID-19 have been quantified by the Office of National StatisticsThese have also been reported across age groups and regionsWhat this study addsWe report the number of excess deaths, using weekly mortality data from 1/1/2010We also quantify the number of excess deaths, excluding COVID-19 associated deaths, which can be attributed to COVID-19 directly (but not coded as such) or indirectly (due to other urgent but unmet health need)Highest excess mortality, excluding COVID-19 deaths, was observed in the West Midlands, followed by London and the North WestAlthough males had larger excess mortality rates than females across all age groups, female excess mortality rates excluding COVID-19 were higher in the 85+ age group, indicating a large undocumented impact of the virus on older females (direct and/or indirect)The three provided appendices will be updated weekly on the BMJ-JECH website, to provide up-to-date information of excess mortality by region, sex and age group

scholarly journals Mortality from idiopathic pulmonary fibrosis: a temporal trend analysis in Brazil, 1979-2014

2017 ◽  
Vol 43 (6) ◽  
pp. 445-450 ◽  
Author(s):  
Eduardo Algranti ◽  
Cézar Akiyoshi Saito ◽  
Diego Rodrigues Mendonça e Silva ◽  
Ana Paula Scalia Carneiro ◽  
Marco Antonio Bussacos
Keyword(s):  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Temporal Trend ◽  
Population Aging ◽  
Age Groups ◽  
International Classification Of Diseases ◽  
Mortality Rates ◽  
Age Group ◽  
Classification Of Diseases ◽  
And Gender

ABSTRACT Objective: To analyze mortality from idiopathic pulmonary fibrosis (IPF) in Brazil over the period 1979-2014. Methods: Microdata were extracted from the Brazilian National Ministry of Health Mortality Database. Only deaths for which the underlying cause was coded as International Classification of Diseases version 9 (ICD-9) 515 or 516.3 (until 1995) or as ICD version 10 (ICD-10) J84.1 (from 1996 onward) were included in our analysis. Standardized mortality rates were calculated for the 2010 Brazilian population. The annual trend in mortality rates was analyzed by joinpoint regression. We calculated risk ratios (RRs) by age group, time period of death, and gender, using a person-years denominator. Results: A total of 32,092 deaths were recorded in the study period. Standardized mortality rates trended upward, rising from 0.24/100,000 population in 1979 to 1.10/100,000 population in 2014. The annual upward trend in mortality rates had two inflection points, in 1992 and 2008, separating three distinct time segments with an annual growth of 2.2%, 6.8%, and 2.4%, respectively. The comparison of RRs for the age groups, using the 50- to 54-year age group as a reference, and for the study period, using 1979-1984 as a reference, were 16.14 (14.44-16.36) and 6.71 (6.34-7.12), respectively. Men compared with women had higher standardized mortality rates (per 100,000 person-years) in all age groups. Conclusion: Brazilian IPF mortality rates are lower than those of other countries, suggesting underdiagnosis or underreporting. The temporal trend is similar to those reported in the literature and is not explained solely by population aging.

scholarly journals Outpatient antibiotic prescribing and demographic factors associated with state-level septicemia mortality rates in US adults

2018 ◽  
Author(s):  
Edward Goldstein ◽  
Marc Lipsitch
Keyword(s):  
Age Groups ◽  
Group Living ◽  
Antibiotic Use ◽  
Mortality Rates ◽  
Antibiotic Prescribing ◽  
Age Group ◽  
Poverty Level ◽  
Sepsis Mortality ◽  
Elderly Age ◽  
Average Annual Temperature

AbstractBackgroundRates of septicemia/sepsis mortality and hospitalization in the US have risen significantly during the recent years, and antibiotic use may contribute to those rates through various mechanisms.MethodsWe used multivariable linear regression to relate state-specific rates of outpatient prescribing overall for fluoroquinolones, penicillins, macrolides, and cephalosporins between 2013-2014 to state-specific rates of septicemia mortality (ICD-10 codes A40-41 present as either the underlying or contributing causes of death) in each of the following age groups of adults: (18-49y, 50-64y, 65-74y, 75-84y, 85+y) between 2013-2014, adjusting for median household income, average annual temperature, age-specific percentages of state residents who (i) lived below the poverty level, (ii) were African American, (iii) lacked health insurance (in non-elderly age groups), and random effects associated with the different US Health and Human Services (HHS) regions.ResultsRates of penicillin prescribing were positively associated with septicemia mortality rates in the analyses for persons aged 65-74y, 75-84y and over 85y. Rates of cephalosporin prescribing were positively associated with septicemia mortality rates in the analyses for persons aged 18-49y and 65-74y. Rates of fluoroquinolone prescribing were positively associated with septicemia mortality rates in the analyses for persons aged 18-49y. Percent African Americans in a given age group was positively associated with septicemia mortality rates in the analyses for age groups over 65y, and 18-49y. Percent of residents in a given age group living below the poverty level was positively associated with septicemia mortality rates in the analysis for persons aged 65-74y.ConclusionsOur results suggest that rates of penicillin prescribing are associated with rates of septicemia mortality in older US adults, while rates of cephalosporin prescribing are associated with rates of septicemia mortality in persons aged 18-49y and 65-74y, and rates of fluoroquinolone prescribing are associated with rates of septicemia mortality in persons aged 18-49y. Further studies are needed to better understand the potential effect of antibiotic replacement in the treatment of different syndromes, such as replacement of fluoroquinolones by other antibiotics, possibly penicillins and cephalosporins following the recent US FDA guidelines on restriction of fluoroquinolone use, on the rates of sepsis mortality.

Secular Change in Mortality from Suicide in Australia during the 20th Century

2007 ◽  
Vol 13 (1) ◽  
pp. 45 ◽  
Author(s):  
Sarah Donaldson ◽  
Peng Bi ◽  
Janet B Hiller
Keyword(s):  
Old Age ◽  
Moving Average ◽  
Age Groups ◽  
Mortality Rates ◽  
Secular Change ◽  
Suicide Mortality ◽  
Age Group ◽  
Suicide Methods ◽  
Early Century ◽  
Age And Sex

To identify secular change in Australian suicide mortality over the period 1907-1998 and to seek possible explanations, a descriptive epidemiological study was conducted. Deaths due to suicide from 1907 to 1998 were identified according to the ICD-9. Trends in overall annual suicide mortality rates for all causes and individual causes were examined using the three-year moving average method, standardised by age and sex. Secular trends for mortality over the study period were examined in various age groups, using linear regression to test the slope. The results indicated that there has been a decline in overall age and sex standardised mortality from suicide over the study period. The death rate dropped from 15.2 per 100,000 in the early century to 13.9 per 100,000 in late century. Despite the overall decline, the female suicide mortality rates increased over the study period. Male suicide mortality rates were significantly higher than female rates over the study period (P<0.0001). Increased suicide rates were observed in the 15-24 and 25-44 year old age groups for both males and females. The group of 65+ year old females also had increased rates. Decreased rates were observed in both the male and female 45-64 year old age group and in the 65+ year old male age group. The three most common suicide methods used by males in 1907 were guns, poisoning and hanging, while for females they were drowning, hanging and poisoning. In 1998 they were changed to hanging, gas and guns for males and hanging, gas and drowning and poisoning (equally third) for females. These trends can be attributed to numerous factors such as economic crisis, world wars, the availability of suicide methods, a person's gender.

Accelerated melanoma mortality rates among middle-aged white males with tumors of all thicknesses.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e21029-e21029
Author(s):  
Juliana Berk-Krauss ◽  
David Polsky ◽  
Jennifer Stein ◽  
Alan Geller
Keyword(s):  
White Women ◽  
Age Groups ◽  
White Men ◽  
Mortality Rates ◽  
Age Group ◽  
Middle Aged ◽  
Mortality Trends ◽  
Men And Women ◽  
And Gender ◽  
Melanoma Mortality

e21029 Background: Effective early detection of melanoma remains one of the most crucial strategies in improving patient prognosis, due to the inverse relationship between primary tumor thickness and survival time. However, recent studies have demonstrated the mortality burden of thin melanomas is at least as severe as that of thicker melanomas. Recognizing specific mortality trends among men and women by age and thickness is essential for establishing targeted melanoma screening efforts. Methods: We evaluated Surveillance, Epidemiology and End Results (SEER) data from 2009-2013. Melanoma thickness was divided into four standard categories: 0.01-1.00mm, 1.01-2.00mm, 2.01-4.00mm and > 4.01 mm. Melanoma mortalities were calculated among white men and women by age and thickness. We used a Bayesian analysis to calculate the probability of an individual dying from a melanoma of a given gender, age, and thickness. We then compared these probabilities between men and women. Results: Among white men, the largest increases in mortality rates occurred in the jump from the 45-49 to 50-54 age group at an increase of 68% for 0.01-1.00mm tumors, and from the 50-54 to 55-59 age group at an increase of 91% for 1.01-2.00mm tumors, 71% 2.01-4.00mm tumors and 80% for > 4.01mm tumors. In white women, mortality rates regardless of thickness increased at a slow incremental pace, across all age groups at an average overall rate of 36%. Mortality rates for white men with < 1mm and 1.01-2mm melanomas were comparable within the age groups less than 64 years, as was the case for white women with tumors of these thicknesses. The probability of a man dying was greater than of a woman for any age or thickness category. Conclusions: Melanoma mortality rate trends are nuanced and can vary significantly by age, thickness, and gender. In white men, mortality rates begin to accelerate sharply around the mid-50s age group. Screening efforts should therefore target detecting melanoma in middle-aged males in the in situ or earliest stage.

scholarly journals Regional differences in cardiac mortality rates in Russia: the role of statistical features

2021 ◽  
Vol 20 (7) ◽  
pp. 2928
Author(s):  
O. M. Drapkina ◽  
I. V. Samorodskaya ◽  
I. S. Yavelov ◽  
V. V. Kashtalap ◽  
O. I. Barbarash
Keyword(s):  
Coefficient Of Variation ◽  
Cardiac Death ◽  
Regional Differences ◽  
Heart Defects ◽  
Age Groups ◽  
Mortality Rates ◽  
Federal State ◽  
Russian Regions ◽  
Mortality Pattern ◽  
European Standard Population

Aim. To analyze the contribution of cardiac causes to all-cause mortality, to characterize the differences in standardized mortality rates (SMRs) in Russian regions, as well as to identify promising directions for improving establishment of cardiovascular death and its coding.Material and methods. We used the Federal State Statistics Service (Rosstat) data on the mortality rate and the average annual population in one-year age groups for 2019. To calculate the SMR, the European Standard Population was used. For each cardiac death, the SMR from 23 causes was calculated, which were combined into 4 groups, and for each of these groups, the regional mean and standard deviation of SMR in Russian regions were estimated.Results. In 2019, the cardiac SMR in Russian regions was 301,02±77,67, which corresponded to 30,5±5,8% of all death causes. At the same time, the coefficient of variation of regional cardiac SMR was 25,8%. In general, in 60,9±13,8% of cases, the cause of cardiac death was chronic diseases, mainly related to atherosclerosis. The proportion of deaths from acute types of coronary artery disease was 17,3±9,7%, deaths not associated with atherosclerosis (heart defects, myocardial diseases, etc.)  — 17,5±8,2%, deaths associated with hypertension  — 4,2±5,2%. The coefficient of variation of regional SMR was 34,66, 64,47, 50,99 and 122,7, respectively.Conclusion. Significant regional differences in SMR from certain cardiac causes and groups of causes, as well as their contribution to mortality pattern, were revealed. It is necessary to continue the research on the methodology of statistical recording of certain cardiovascular diseases.

scholarly journals Mortality rate of gastric cancer in the population of Belgrade for 1990-2002 period

2005 ◽  
Vol 62 (9) ◽  
pp. 655-660 ◽  
Author(s):  
Sandra Sipetic ◽  
Hristina Vlajinac ◽  
Isidora Ratkov ◽  
Jelena Marinkovic
Keyword(s):  
Gastric Cancer ◽  
Mortality Rate ◽  
Age Groups ◽  
Mortality Rates ◽  
World Population ◽  
Age Group ◽  
The Past ◽  
Mortality Ratio ◽  
Trend Functions ◽  
Annual Decline

Background. Worldwide, gastric cancer is the fourth leading cause of diseases, and the second leading cause of cancer deaths. Aim. To analyze the differences between men and women in mortality rate of gastric cancer in Belgrade from 1990?2002. Methods. Mortality rates standardized directly to the ?World population?, and regression analysis were used. Results. In Belgrade population, 29.2% out the total number of deaths attributable to cancer were caused by gastric cancer. Gastric cancer was the second most common cause of death among digestive tract cancers. In women, in the period between 1990 and 1993, an average annual decline of mortality was 9.0% (95% confidence interval (CI) = 5.9?13.1), and between 1994 and 2002, an average annual increase was 10.3% (CI = 8.4?12.6). Mortality rate series of gastric cancer in men did not fit any of the usual trend functions. The male/female gastric cancer mortality ratio was 1.7 : 1. Mortality rates for gastric cancer rose with age in both sexes and they were highest in the age group of 70 and more years. From 1990?2002, in both sexes aged 70 years and more, mortality from gastric cancer rose by 67.2% (CI = 58.0?76.4) in men and by 69.6% (CI = 60.6?78.6) in women. During the same period, the death rates in men decreased by 75.9 % (CI = 67.5?84.4) in the age group of 30?39 years, and by 48.1% (CI = 38.4?57.9) in women aged 50?59 years. In both sexes mortality rate series of all other age groups did not fit any of the usual trend functions. Conclusions. The increase in mortality rate of gastric in women over the past few years, showed the necessity of instituting primary and secondary preventive measures.

scholarly journals Age separation dramatically reduces COVID-19 mortality rate in a computational model of a large population

2020 ◽  
Author(s):  
Liron Mizrahi ◽  
Shani Stern
Keyword(s):  
Elderly Population ◽  
Large Population ◽  
Age Groups ◽  
The Elderly ◽  
Mortality Rates ◽  
Social Connections ◽  
Age Group ◽  
Efficient Treatment ◽  
Age Related ◽  
Total Death

AbstractCOVID-19 pandemic has caused a global lock down in many countries throughout the world. Faced with a new reality, and until a vaccine or efficient treatment is found, humanity must figure out ways to keep economy going on one hand, yet keep the population safe on the other hand, especially those that are susceptible to this virus. Here we use a network simulation, with parameters that were drawn from what is known about the virus, to explore 5 different scenarios of partial lock down release. We find that separating age groups by reducing interactions between age groups, protects the general population and reduces mortality rates. Furthermore, addition of new connections within the same age group to compensate for the lost connections outside the age group, still has a strong beneficial influence and reduces the total death toll by 66%. While complete isolation from society may be the most protective scenario for the elderly population, it would have an emotional and possibly cognitive impact that might outweigh its benefit. We therefore propose creating age-related social recommendations or even restrictions, thereby allowing social connections but still strong protection for the older population.

Current state of mortality of the working-age population in Russia and Europe

2020 ◽  
Vol 60 (11) ◽  
pp. 756-759
Author(s):  
Tatyana Yu. Gorchakova ◽  
Anastasiya N. Churanova
Keyword(s):  
European Union ◽  
Age Groups ◽  
Mortality Rates ◽  
Age Group ◽  
The European Union ◽  
Current State ◽  
Working Age ◽  
Working Age Population ◽  
State Programs ◽  
The Eu

Introduction. Issues of preserving the health and saving of the Russian population are important in the development of state programs. One of the main sources of population growth, as well as the preservation of the labor potential of our country, is the reduction of the death rate of the working - age population. The aim of the study was to analyze the mortality of the population in the age groups 15-59 years and 15-64 years for men and 15-54 years and 15-59 years for women in Russia in comparison with the countries of the European Union (EU-28). Materials and methods. Mortality was studied based on data from Rosstat and the WHO Mortality Database and the Human Mortality Database. Age-standardized mortality rates were calculated for Russia in 2018 and the EU-28 countries in 2017 (European standard, revised 2013). Results. Comparative analysis of the standardized mortality rates of the population 15 to 59 years and 15-64 years for men and 15-54 years of age and 15-59 years of age showed a significant gap between Russia and the EU-28. Differences in mortality among men in comparison with the EU-28 in the age group of 15-59 years was 3.1 times, and in the age group 15-64 years - by 2.8 times. In women aged 15-54 years, the excess was 2.5 times, and in those aged 15-59 years - 2.2 times. Conclusions. Thus, the analysis of modern data on the mortality of the male (aged 15-59 and 15-64 years) and female (aged 15-54 and 15-59 years) populations indicated that negative trends persist in Russia's lagging behind the European Union countries.

scholarly journals Coronary heart disease incidence still decreased between 2006 and 2014 in France, except in young age groups: Results from the French MONICA registries

2020 ◽  
Vol 27 (11) ◽  
pp. 1178-1186 ◽  
Author(s):  
Aline Meirhaeghe ◽  
Michèle Montaye ◽  
Katia Biasch ◽  
Samantha Huo Yung Kai ◽  
Marie Moitry ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Age Groups ◽  
Coronary Event ◽  
Mortality Rates ◽  
Percentage Change ◽  
Age Group ◽  
Acute Coronary Event ◽  
Annual Percentage Change ◽  
Men And Women

Background Over the past few decades decreases in coronary heart disease morbidity and mortality rates have been observed throughout the western world. We sought to determine whether the acute coronary event rates had decreased between 2006 and 2014 among French adults, and whether there were sex and age-specific differences. Methods We examined the French MONICA population-based registries monitoring the Lille urban area in northern France, the Bas-Rhin county in north-eastern France and the Haute Garonne county in south-western France. All acute coronary events among men and women aged 35–74 were collected. Results Over the study period, the age-standardised attack rates decreased in both men (annual percentage change −1.5%, P = 0.0006) and women (annual percentage change −2.1%, P = 0.002). Also, the age-standardised incidence rates decreased in both men (annual percentage change −0.9%, P = 0.03) and women (annual percentage change −1.8%, P = 0.002) due to decreases in the 65–74 year age group. In men, age-standardised mortality rates decreased by 3.5% per year ( P = 0.0004), especially in the 55–64 and 65–74 year age groups. In women, these rates decreased by 4.3% per year ( P = 0.0009), particularly in the 35–44 and 65–74 year age groups. We also observed significant decreases in case fatality among both men (annual percentage change −1.7%, P < 0.0001) and women (annual percentage change −1.9%, P = 0.009). Conclusions Downward trends in acute coronary event attack, incidence and mortality rates were observed between 2006 and 2014 in men and women. This effect was age dependent and was primarily due to decreases in the 65–74 year age group. There were no substantial declines in the younger age groups except for mortality in young women. Prevention measures still need to be strengthened, particularly in young adults.

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