Metabolic health, menopause, and physical activity—a 4-year follow-up study

Abstract Background In women, metabolic health deteriorates after menopause, and the role of physical activity (PA) in mitigating the change is not completely understood. This study investigates the changes in indicators of metabolic health around menopause and evaluates whether PA modulates these changes. Methods Longitudinal data of 298 women aged 48–55 years at baseline participating in the ERMA and EsmiRs studies was used. Mean follow-up time was 3.8 (SD 0.1) years. Studied indicators of metabolic health were total and android fat mass, waist circumference, waist-to-hip ratio (WHR), systolic (SBP) and diastolic (DBP) blood pressure, blood glucose, triglycerides, serum total cholesterol, and high- (HDL-C) and low-density (LDL-C) lipoprotein cholesterol. PA was assessed by accelerometers and questionnaires. The participants were categorized into three menopausal groups: PRE-PRE (pre- or perimenopausal at both timepoints, n = 56), PRE-POST (pre- or perimenopausal at baseline, postmenopausal at follow-up, n = 149), and POST-POST (postmenopausal at both timepoints, n = 93). Analyses were carried out using linear and Poisson mixed-effect models. Results At baseline, PA associated directly with HDL-C and inversely with LDL-C and all body adiposity variables. An increase was observed in total (B = 1.72, 95% CI [0.16, 3.28]) and android fat mass (0.26, [0.06, 0.46]), SBP (9.37, [3.34, 15.39]), and in all blood-based biomarkers in the PRE-POST group during the follow-up. The increase tended to be smaller in the PRE-PRE and POST-POST groups compared to the PRE-POST group, except for SBP. The change in PA associated inversely with the change in SBP (−2.40, [−4.34, −0.46]) and directly with the change in WHR (0.72, [0.05, 1.38]). Conclusions In middle-aged women, menopause may accelerate the changes in multiple indicators of metabolic health. PA associates with healthier blood lipid profile and body composition in middle-aged women but does not seem to modulate the changes in most of the studied metabolic health indicators during the menopausal transition.

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Effects of Vitamin C, E Intake to Body Composition, VO(2)max, Blood Lipid Profile, Malondialdehyde Value and Total Antioxidant Status in Middle-aged Obese Women

Journal of Sport and Leisure Studies ◽

10.51979/kssls.2010.08.41.873 ◽

2010 ◽

Vol 41 ◽

pp. 873-881

Author(s):

Jum Hong Yang ◽

Soon Duk Jung ◽

Jae Hyun Choi

Keyword(s):

Body Composition ◽

Vitamin C ◽

Lipid Profile ◽

Antioxidant Status ◽

Total Antioxidant Status ◽

Blood Lipid ◽

Obese Women ◽

Middle Aged ◽

Blood Lipid Profile ◽

Total Antioxidant

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Influence of Moderate, Daily Physical Activity On Body Composition and Blood Lipid Profile in Swedish Adults

Journal of Physical Activity and Health ◽

10.1123/jpah.9.6.867 ◽

2012 ◽

Vol 9 (6) ◽

pp. 867-874 ◽

Cited By ~ 10

Author(s):

Peter Pagels ◽

Anders Raustorp ◽

Trevor Archer ◽

Ulf Lidman ◽

Marie Alricsson

Keyword(s):

Physical Activity ◽

Energy Expenditure ◽

Lipid Profile ◽

Inverse Correlation ◽

Blood Lipid ◽

Daily Physical Activity ◽

Moderate Intensity ◽

Control Group ◽

Brisk Walking ◽

Blood Lipid Profile

Background:Health organizations suggest that adults ought to engage in at least 30 minutes of moderate-intensity daily physical activity. This study investigated the effects of a 30-minute single daily bout of brisk walking upon risk factors for coronary heart disease with blood lipid profile in particular.Methods:Thirty-three (25–45 y) adults, were randomly assigned into an exercise group (EG; n = 16, 9w) and a control group (CG; n = 17, 6w). The EG walked briskly 30 minutes daily during the 3-week test period. Compliance/adherence was maximal throughout the 3-week intervention due to stringent daily monitoring.Results:The EG showed a significant decrease in concentrations of low density lipoprotein cholesterol (LDL-C) and total cholesterol (TC) during the intervention period. A significant inverse correlation between Δ energy expenditure/day and Δ LDL-C (r = –0.39, P < .05) and an improvement in weight and BMI in the EG was found. Average steps during 30 minutes brisk walking bout was 3669 steps/bout generating a mean energy expenditure of 191 kcal/ bout.Conclusions:The most unique findings were that daily single bouts of moderate-intensity physical activity for 30 minutes, during 3 weeks, induced favorable effects upon body weight, BMI, and blood concentration of LDL-C and TC in healthy adults.

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High-intensity physical activity is not associated with better cognition in the elder: evidence from the China Health and Retirement Longitudinal Study

Alzheimer s Research & Therapy ◽

10.1186/s13195-021-00923-3 ◽

2021 ◽

Vol 13 (1) ◽

Author(s):

Zhiyuan Wu ◽

Haiping Zhang ◽

Xinlei Miao ◽

Haibin Li ◽

Huiying Pan ◽

...

Keyword(s):

Physical Activity ◽

Longitudinal Study ◽

Episodic Memory ◽

Cognitive Performance ◽

Sensitivity Analyses ◽

Cross Sectional ◽

Mixed Effect ◽

Global Cognition

Abstract Background To evaluate the association of physical activity (PA) intensity with cognitive performance at baseline and during follow-up. Methods A total of 4039 participants aged 45 years or above from the China Health and Retirement Longitudinal Study were enrolled in visit 1 (2011–2012) and followed for cognitive function in visit 2 (2013–2014), visit 3 (2015–2016), and visit 4 (2017–2018). We analyzed the association of PA intensity with global cognition, episodic memory, and mental intactness at baseline using adjusted regression methods and evaluated the long-term effect of PA intensity using multiple measures of cognition scores by mixed effect model. Results In cross-sectional analysis, mild and moderate PA, rather than vigorous PA, was associated with better cognitive performance. The results remained consistent in multiple sensitivity analyses. During the follow-up, participant with mild PA had a 0.56 (95% CI 0.12–0.99) higher global cognition, 0.23 (95% CI 0.01–0.46) higher episodic memory, and 0.33 (95% CI 0.01–0.64) higher mental intactness, while those with moderate PA had a 0.74 (95% CI 0.32–1.17) higher global score, 0.32 (95% CI 0.09–0.54) higher episodic memory, and 0.43 (95% CI 0.12–0.74) higher mental intactness, compared with individuals without PA. Vigorous PA was not beneficial to the long-term cognitive performance. Conclusions Our study indicates that mild and moderate PA could improve cognitive performance, rather than the vigorous activity. The targeted intensity of PA might be more effective to achieve the greatest cognition improvement considering age and depressive status.

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Relationship between Physical Activity and Blood Lipid Profile in Residents of Yazd City (YaHS Study)

Journal of Shahid Sadoughi University of Medical Sciences ◽

10.18502/ssu.v28i7.4266 ◽

2020 ◽

Author(s):

Masoud Mirzaei ◽

Farnaz Nekahi

Keyword(s):

Physical Activity ◽

Blood Lipid ◽

Activity Level ◽

Health Study ◽

General Level ◽

Statistical Relationship ◽

Physical Activity Intensity ◽

Blood Lipid Profile ◽

Cross Sectional ◽

Activity Intensity

Introduction: Inadequate physical activity is one of the causes of fat disorders and regular physical activity is one of the important factors in correcting fat disorders. The aim of this study was to determine the relationship between physical activity levels and blood lipids as a risk factor for cardiovascular disease. Methods: This analytical cross sectional study was conducted using the information of the registration phase of the Yazd People's Health Study on 9962 residents of Yazd in the age group of 20 to 70 years between 2014 and 2015. Study data were obtained using standard questionnaires and participants' blood samples. SPSS software, version 21, t-test, linear regression, and OR comparison of fat disorders were used in the physical activity intensity classes. Results: In the study sample, 49.4% are men. No statistical significant physical activity level was found in the study of the ratio of chance of fat disorder. Moreover, no significant relationship was observed in the study of the linear relationship between the general level of physical activity and fat profile components (p> 0.05). It should be noted that a significant statistical relationship was observed between the level of TC or blood total cholesterol and blood triglycerides with sex, body mass index and family history and some age groups. (p <0.05). Conclusion: In the analysis of the data of this study, no significant statistical relationship was found between blood lipid levels and physical activity.

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Diet, blood lipid profile and physical activity patterns in primary school children from a semi-rural area of Greece

Journal of Human Nutrition and Dietetics ◽

10.1111/j.1365-277x.2006.00675.x ◽

2006 ◽

Vol 19 (2) ◽

pp. 101-112 ◽

Cited By ~ 14

Author(s):

F. Magkos ◽

I. Piperkou ◽

Y. Manios ◽

C. Papoutsakis ◽

N. Yiannakouris ◽

...

Keyword(s):

Physical Activity ◽

Primary School ◽

Lipid Profile ◽

Rural Area ◽

School Children ◽

Activity Patterns ◽

Blood Lipid ◽

Primary School Children ◽

Blood Lipid Profile ◽

Of Greece

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Influence of the Basal Metabolic Profile on the Evolution of the Pediatric Patient with Obesity

Austin Journal of Obesity & Metabolic Syndromes ◽

10.26420/austinjobesmetabsynd.2021.1024 ◽

2021 ◽

Vol 5 (1) ◽

Author(s):

Fernández Fernandez B ◽

◽

Sarasua Miranda ◽

Lorente Blazquez I ◽

Diez López ID ◽

...

Keyword(s):

Physical Activity ◽

Childhood Obesity ◽

Physical Exercise ◽

Fat Mass ◽

Pediatric Population ◽

Fat Content ◽

The Body ◽

Basal Metabolism ◽

Protection Factor

Purpose: To study how basal metabolism influences the somatometric evolution of the child and adolescent population with obesity in a pediatric endocrinology clinic. Material and Methods: Study of the entire population diagnosed with childhood obesity in a tertiary hospital by means of a multichannel impedanceometry study, TANITA BF 430. Results: 100 patients were selected by chance and studied from a database with 1400 records. Most of the patients who attend to these consultations for obesity are girls, between 8 and 11 years old. All the patients studied had a basal metabolism lower than the calculated theoretical ideal. The group of boys at the beginning of their follow-up showed a higher basal metabolism and more similar than the group of girls. Girls had a higher amount of fat mass compared to boys at the beginning of their follow up. After their first year of follow-up, both groups achieved a decrease in the percentage of fat mass, double in the case of boys compared to girls. After three years of the study, it was observed that 54% of the boys achieved a reduction in their FM compared to 36% of the girls. In overall terms, weight reduction is not achieved in this pediatric population. However it is observed a decrease in fat content in the medium term (1-3 years). The reduction of this fat mass could be a protection factor against cardiovascular diseases in adults. Given the same adherence to nutritional programs, it is believed that physical exercise rates influence this reduction. It was also observed that the most relevant data in the evolution of obesity in these patients is the basal metabolism that they present at the beginning of their follow-up. Discussion: Childhood obesity is a problem of increasing importance in our society. Understanding its characteristics would allow different strategies to be taken for a better treatment and diagnosis of these cases. Boys, in general, achieve a greater reduction in fat mass in the same follow-up time. Due to sexual dimorphism, or a higher rate of physical activity. Bioelectrical impedanceometry measurement is a simple, cheap and easy to use method in clinical practice to evaluate the energy consumption and the body composition of the patient. In “healthy child” health programs and even in schools, an impedanceometry machine could be purchased to focus physical activity efforts on those boys and girls with a lower basal metabolism, adding a greater consumption factor such as physical exercise. Thus, it would be possible to increase the requirements and the basal metabolism of the patient would increase, favoring the loss of fat mass. Regarding the use of conventional scales, in this type of patients, if we only look at the weight variable, a bias could be created since it would not be noticed that there has been a decrease in fat content at the cost of an increase in muscle mass. Conclusion: We consider that it should be recommendable to supply with a multichannel impedanceometry every pediatric endocrine consultation room as it is a non-invasive, and easy-to-use test that can provide a great amount of information about the evolution of these patients, since we believe that focusing efforts on those boys and girls who have a worse basal metabolism could contribute to improving the efficiency and effectiveness of the scarce health resources that we have.

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Longitudinal changes in body composition and waist circumference by self-reported levels of physical activity in leisure among adolescents: the Tromsø study, Fit Futures

BMC Sports Science Medicine and Rehabilitation ◽

10.1186/s13102-019-0150-8 ◽

2019 ◽

Vol 11 (1) ◽

Cited By ~ 1

Author(s):

Nils Abel Aars ◽

Bjarne K. Jacobsen ◽

Bente Morseth ◽

Nina Emaus ◽

Sameline Grimsgaard

Keyword(s):

Physical Activity ◽

Body Composition ◽

Waist Circumference ◽

Fat Mass ◽

Lean Mass ◽

Leisure Time ◽

Leisure Time Physical Activity ◽

First Year ◽

Fat Mass Index

Abstract Background It is not clear how physical activity affects body composition in adolescents. Physical activity levels are often reduced during this period, and the relative proportion of body fat mass and lean mass undergo natural changes in growing adolescents. We aimed to examine whether self-reported physical activity in leisure time at baseline or change in activity during follow-up affect changes in four measures of body composition; body mass index (kg/m2), waist circumference, fat mass index (fat mass in kg/m2) and lean mass index (lean mass in kg/m2). Methods We used data from the Tromsø Study Fit Futures, which invited all first year students in upper secondary high school in two municipalities in northern Norway in 2010–2011. They were reexamined in 2012–2013. Longitudinal data was available for 292 boys and 354 girls. We used multiple linear regression analyses to assess whether self-reported level of physical activity in leisure time at baseline predicted changes in body composition, and analysis of covariance to assess the effects of change in level of activity during follow-up on change in body composition. All analyses were performed sex-specific, and a p-value of < 0.05 was considered statistically significant. Results There were no associations between self-reported leisure time physical activity in the first year of upper secondary high school and changes in any of the considered measure of body composition after 2 years of follow up, with the exception of waist circumference in boys (p = 0.05). In boys, change in fat mass index differed significantly between groups of activity change (p < 0.01), with boys adopting activity or remaining physically active having less increase in fat mass index than the consistently inactive. In girls, change in lean mass index differed significantly between groups of activity change (p = 0.04), with girls adopting physical activity having the highest increase. Conclusions Self-reported leisure time physical activity does not predict changes in body composition in adolescents after 2 years of follow up. Change in the level of physical activity is associated with change in fat mass index in boys and lean mass index in girls.

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Changes in Leisure-Time Physical Activity and Subsequent Sickness Absence Due to Any Cause, Musculoskeletal, and Mental Causes

Journal of Physical Activity and Health ◽

10.1123/jpah.2015-0442 ◽

2016 ◽

Vol 13 (8) ◽

pp. 867-873 ◽

Cited By ~ 4

Author(s):

Ansku Holstila ◽

Ossi Rahkonen ◽

Eero Lahelma ◽

Jouni Lahti

Keyword(s):

Physical Activity ◽

Sickness Absence ◽

Social Insurance ◽

Leisure Time ◽

Negative Binomial ◽

Response Rate ◽

Leisure Time Physical Activity ◽

Activity Level ◽

Middle Aged

Background:The association between changes in physical activity and sickness absence is poorly understood. The aim of this study was to examine the association between changes in leisure-time physical activity and long-term sickness absence due to any cause and musculoskeletal and mental causes.Methods:We measured physical activity at baseline in 2000–2002 (response rate 67%) and at follow-up in 2007 (response rate 83%) among middle-aged employees of the City of Helsinki, Finland. The survey data were linked to the Finnish Social Insurance Institute’s register data on sickness benefit periods > 9 days, including diagnoses (ICD-10; International Statistical Classification of Diseases and Related Health Problems, 10th revision) (mean follow-up 2.3 years). We used a negative binomial model to calculate rate ratios. The analyses included 4010 respondents (81% women).Results:Those who were persistently vigorously active and those whose physical activity level changed from low to moderate or vigorous, from moderate to vigorous, or from vigorous to moderate were at lower risk for sickness absence than were the persistently low-activity group. For sickness absence due to musculoskeletal causes, vigorous activity showed stronger associations, whereas mental causes showed no such associations.Conclusions:To reduce sickness absence due to both musculoskeletal and mental causes, middle-aged and aging employees should be encouraged to engage in physical activity.

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