Influence of alcohol consumption and various beverages on waist girth and waist-to-hip ratio in a sample of French men and women

AbstractObjectiveAlcohol consumption may play a role in the development of obesity but the relationship between alcohol and weight is still unclear. The aim of our study was to assess the cross-sectional association of intakes of total alcohol and of specific alcoholic beverages (wine, beer and spirits) with waist-to-hip ratio (WHR) and body mass index (BMI) in a large sample of adults from all over France.DesignCross-sectional.SettingParticipants were free-living healthy volunteers of the SU.VI.MAX study (an intervention study on the effects of antioxidant supplementation on chronic diseases).SubjectsFor 1481 women aged 35–60 years and 1210 men aged 45–60 years, intakes of total alcohol and specific alcoholic beverages were assessed by six 24-hour dietary records. BMI and WHR were measured during a clinical examination the year after.ResultsA J-shaped relationship was found between total alcohol consumption and WHR in both sexes and between total alcohol consumption and BMI in men only (P < 0.05). The same relationships were observed with wine (P < 0.05); men and women consuming less than 100 g day−1 had a lower BMI (men only) and WHR than non-drinkers or those consuming more. Spirits consumption was positively associated with BMI (linear regression coefficient β = 0.21, 95% confidence interval (CI): 0.09–0.34 and β = 0.22, 95% CI: 0.06–0.39 for men and women, respectively) and WHR (β = 0.003, 95% CI: 0.001–0.005 and β = 0.003, 95%CI: 0.0002–0.006) in both sexes in a linear fashion. No relationship between beer consumption and BMI or WHR was found.ConclusionIf confirmed in longitudinal studies, our results indicate that consumption of alcoholic beverages may be a risk factor for obesity.

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Association of cardiovascular risk factors with markers of endothelial dysfunction in middle-aged men and women

Thrombosis and Haemostasis ◽

10.1160/th05-08-0552 ◽

2006 ◽

Vol 95 (01) ◽

pp. 134-141 ◽

Cited By ~ 24

Author(s):

Barbara Thorand ◽

Jens Baumert ◽

Angela Döring ◽

Andrea Schneider ◽

Lloyd Chambless ◽

...

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Cardiovascular Risk ◽

Endothelial Dysfunction ◽

Alcohol Consumption ◽

Cardiovascular Risk Factors ◽

Linear Regression Analysis ◽

High Body Mass Index ◽

Moderate Alcohol Consumption ◽

Men And Women

SummaryEndothelial dysfunction plays an important role in the pathogenesis of cardiovascular diseases and diabetes mellitus. However, the causes underlying endothelial dysfunction are not fully understood. Therefore, the aim of the present study was to investigate associations of cardiovascular risk factors with soluble adhesion molecules (sE-Selectin, sICAM-1), soluble thrombomodulin (sTM) and von Willebrand factor (vWF) as markers of endothelial dysfunction. The study population consisted of a subcohort of 2,168 men and women aged 35 to 74 years randomly drawn from three cross-sectional population-based MONICA/ KORA Augsburg surveys conducted between 1984 and 1995. In multivariable linear regression analysis, current smoking, high (versus moderate) alcohol consumption, ratio of total cholesterol/HDL-cholesterol (TC/HDL-C) and C-reactive protein (CRP) were significantly associated with elevated levels of sEselectin and sICAM-1. Increased levels of sE-selectin were also found in subjects with actual hypertension, high body mass index and prevalent diabetes mellitus. In addition, low physical activity and no (versus moderate) alcohol consumption were significantly associated with elevated concentrations of sICAM-1. Levels of sTM were higher in subjects with actual hypertension, no or high amounts of alcohol intake and a high ratio of TC/ HDL-C, but were lower in subjects witha history of myocardial infarction. VWF was significantly associated with CRP only. In conclusion, sE-selectin and sICAM-1 are more strongly associated with traditional cardiovascular risk factors than sTM and vWF.

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P2-189 Prevalence and patterns of alcohol consumption in Chinese men and women: the Kadoorie Biobank Study of 0.5 million people in China

Journal of Epidemiology & Community Health ◽

10.1136/jech.2011.142976j.24 ◽

2011 ◽

Vol 65 (Suppl 1) ◽

pp. A273-A273

Author(s):

I. Millwood ◽

L. Lee ◽

L. Yang ◽

G. Yu ◽

R. Collins ◽

...

Keyword(s):

Alcohol Consumption ◽

Men And Women ◽

Chinese Men

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Allostatic Load of Men and Women in Early Middle Age

Journal of Individual Differences ◽

10.1027/1614-0001.26.1.20 ◽

2005 ◽

Vol 26 (1) ◽

pp. 20-28 ◽

Cited By ~ 15

Author(s):

Marja-Liisa Kinnunen ◽

Jaakko Kaprio ◽

Lea Pulkkinen

Keyword(s):

Longitudinal Study ◽

Allostatic Load ◽

Middle Age ◽

Glycosylated Hemoglobin ◽

Density Lipoprotein ◽

Dehydroepiandrosterone Sulfate ◽

Men And Women ◽

Waist To Hip Ratio ◽

Physical Responses

Abstract. The present longitudinal study investigated three aspects of allostatic load, a long-term negative consequence of physical responses to stress: (1) sex differences in allostatic load in early middle age, (2) associations between career stability history and allostatic load, and (3) relationships between allostatic load and health problems. Participants consisted of 62 men and 55 women from the ongoing Jyväskylä Longitudinal Study of Personality and Social Development, Finland. Allostatic load was the sum of eight parameters (dehydroepiandrosterone-sulfate, 12-h urinary norepinephrine, high-density lipoprotein, triglycerides, glycosylated hemoglobin, systolic and diastolic blood pressure, and waist-to-hip ratio) for which the participant fell into the high-risk quartile. Results showed that 41.9% of men and 21.8% of women had an elevated allostatic load at age 42. Participants with preceding unstable career assessed prospectively at age 36 had an over three-fold risk for high allostatic load six years later compared to participants with a stable career history; sex, alcohol consumption, and smoking were adjusted for in the models. Furthermore, participants with high allostatic load reported having more psychosomatic symptoms. The results reveal that an unstable career as a long-term stressful life condition may have long-lasting effects on health.

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Abstract P282: Does Cardiorespiratory Fitness Modify the Association Between Sitting Time and Obesity?

Circulation ◽

10.1161/circ.131.suppl_1.p282 ◽

2015 ◽

Vol 131 (suppl_1) ◽

Author(s):

Carolyn E Barlow ◽

Kerem Shuval ◽

Bijal Balasubramanian ◽

Darla E Kendzor ◽

Carrie E Finley ◽

...

Keyword(s):

Cardiorespiratory Fitness ◽

Body Fat ◽

Smoking Status ◽

Statistical Significance ◽

Sitting Time ◽

Percent Body Fat ◽

Healthy Population ◽

Men And Women ◽

Waist Girth ◽

Product Term

Purpose: To examine the association between sitting time and markers of obesity in healthy men and women and explore the potential modifying role of estimated cardiorespiratory fitness (CRF). Methods: A cross-sectional analysis of 4,486 men and 1,845 women enrolled in the Cooper Center Longitudinal Study for the period 2010-2013 was conducted. Key exposures included self-reported sitting time and CRF. Sitting time was self-reported as 1) almost none of the time (about 0%), 2) approximately one quarter of the time (about 25%), 3) approximately half of the time (about 50%), 4) approximately three quarters of the time (about 75%), and 5) almost all of the time (about 100%). CRF was estimated from time spent on a treadmill during a graded exercise test. Obesity outcomes were defined in three ways: 1) waist girth (≥102 cm for men; ≥88 cm for women); 2) BMI (≥30 kg/m2); and 3) percent body fat (≥25% for men; ≥30% for women). Sex-specific multivariable models were constructed to examine the association between sitting time and each obesity outcome, separately, and adjusted for covariates including age, physical activity, smoking status, and alcohol consumption. A cross product term of sitting time and CRF was included in the full model to assess the possibility of effect modification. Results: In unadjusted analysis, obesity outcomes significantly varied across categories of sitting time in men and women. In men, significant associations were observed between sitting 75% of the time or more and each measure of adiposity which remained after adjustment for CRF and other covariates. For example, men who sat about 100% of the time were more than two times as likely to be obese whether defined by waist girth (OR: 2.61; 95% CI: 1.25, 5.47), or percent body fat (OR: 3.33; 95% CI: 1.35, 8.20) relative to men who sat about 0% of the time. Similar to the results for men, associations between sitting time and each measure of adiposity were seen in women when adjusted for age. However, when CRF and other covariates were added to the model, these associations were no longer statistically significant. In addition, the sitting time x CRF terms did not reach statistical significance for any obesity outcome. Conclusion: In this healthy population, the relation between obesity and sitting time varied by sex. Men who sat more were more likely to be obese by any definition. However, no significant associations were observed between sitting time and obesity among women after adjustment for CRF and other covariates. In addition, CRF did not appear to modify this association in either men or women. These results suggest that women, at least, can offset sedentary behavior by being fit. Further research is needed to understand the disparate effects of sitting time on obesity as seen in these healthy women. Furthermore, prospective research studies are needed to elucidate the causal association between obesity and sitting time.

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Psychiatric Disorders and Alcohol Consumption Among Low-Income African Americans:Gender Differences

Brain Sciences ◽

10.3390/brainsci9040086 ◽

2019 ◽

Vol 9 (4) ◽

pp. 86 ◽

Cited By ~ 1

Author(s):

Sharon Cobb ◽

Shervin Assari

Keyword(s):

Alcohol Consumption ◽

Alcohol Use ◽

Linear Regression ◽

Low Income ◽

Regression Models ◽

Future Research ◽

Linear Regression Models ◽

Cross Sectional ◽

Men And Women ◽

Compulsive Disorder

Background: Although cooccurrence of nonsubstance use disorders (non-SUDs) and substance use is well-established in the literature, most of what we know in this regard is derived from studies that have recruited predominantly White sample populations. As a result, there is a gap in knowledge on this link among low-income African Americans (AAs). There is also a need to understand how low-income AA men and women differ in these associations. Objective: To study whether there is an association between number of non-SUDs and amount of alcohol consumption by AA adults, and whether this association varies between AA men and women. Methods: This cross-sectional study recruited a nonrandom sample of 150 AA adults with non-SUDs (i.e., major depression, bipolar disorders, obsessive–compulsive disorder, paranoid disorder, panic disorder, posttraumatic stress disorder (PTSD), and schizoaffective disorder). The independent variable was the number of non-SUDs. The dependent variable was the amount of alcohol consumption. Age, socioeconomic status (educational attainment and household income), and self-rated health were covariates. Gender was the moderator. Linear regression models were used to analyze the data. Results: A higher number of non-SUDs was not associated with a higher amount of alcohol use in the pooled sample of AA adults. We, however, found a significant interaction between gender and number of non-SUDs on the amount of alcohol use, suggesting a stronger effect of non-SUDs on alcohol consumption in AA men than in AA women. Gender-stratified linear regression models showed a positive association between number of non-SUDs and amount of alcohol consumption in AA men but not in AA women. Conclusion: Non-SUDs impact alcohol use of AA men but not women. Future research should test whether AA men may have a higher tendency to turn to alcohol to regulate their emotions and cope with psychological pain due to multiple non-SUDs. The results also suggest that integration of services for SUDs and non-SUDs may be more relevant to provision of mental health services for AA men than AA women.

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Alcohol Consumption and Risk of First-Time Venous Thromboembolism in Men and Women

Thrombosis and Haemostasis ◽

10.1055/s-0039-1681100 ◽

2019 ◽

Vol 119 (06) ◽

pp. 962-970 ◽

Cited By ~ 5

Author(s):

Magdalena Johansson ◽

Lars Johansson ◽

Maria Wennberg ◽

Marcus Lind

Keyword(s):

Venous Thromboembolism ◽

Alcohol Consumption ◽

Alcohol Dependence ◽

Population Based ◽

Health Examination ◽

Standard Drink ◽

Men And Women ◽

Increased Risk ◽

The Mean ◽

First Time

Background The relationship between alcohol intake and risk of venous thromboembolism (VTE) is unclear. Men and women differ in their drinking habits, which may affect a possible association. Objective This article investigates the association between alcohol consumption, alcohol dependence and VTE in the total population as well as in men and women separately. Methods We performed a prospective, population-based cohort study in northern Sweden. Study participants were 108,025 (51% women) persons aged 30 to 60 years who underwent a health examination between 1985 and 2014. We assessed alcohol consumption and defined alcohol dependence using a questionnaire. The outcome was a validated first-time VTE. Results The mean follow-up time was 13.9 years, and 2,054 participants had a first-time VTE. The mean alcohol consumption was 3.5 standard drinks weekly in men and 1.5 in women. Alcohol dependence was found in 10% of men and 3% of women. There was an association between alcohol consumption (hazard ratio [HR], 1.02; 95% confidence interval [CI], 1.00–1.03 per standard drink weekly) as well as alcohol dependence (HR, 1.27; 95% CI, 1.06–1.52) and VTE after adjustments. In men, the risk of VTE increased over quartiles of weekly alcohol consumption (p for trend 0.02), with a HR of 1.22 (95% CI, 1.01–1.47) for the highest quartile. Alcohol dependence was associated with VTE in men (HR, 1.30; 95% CI, 1.07–1.59). In women, there were no significant associations. Conclusion High alcohol consumption and alcohol dependence were associated with increased risk of first-time VTE in men, but not in women.

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Impact of evening alcohol consumption on nocturnal autonomic and cardiovascular function in adult men and women: a dose–response laboratory investigation

SLEEP ◽

10.1093/sleep/zsaa135 ◽

2020 ◽

Author(s):

Massimiliano de Zambotti ◽

Mohamad Forouzanfar ◽

Harold Javitz ◽

Aimee Goldstone ◽

Stephanie Claudatos ◽

...

Keyword(s):

Blood Pressure ◽

Alcohol Consumption ◽

Blood Pressure Monitoring ◽

Alcohol Ingestion ◽

High Dose ◽

Standard Drink ◽

Men And Women ◽

Adult Men ◽

Alcohol Dose ◽

Moderate Alcohol Intake

Abstract Study Objectives To investigate the dose-dependent impact of moderate alcohol intake on sleep-related cardiovascular (CV) function, in adult men and women. Methods A total of 26 healthy adults (30–60 years; 11 women) underwent 3 nights of laboratory polysomnographic (PSG) recordings in which different doses of alcohol (low: 1 standard drink for women and 2 drinks for men; high: 3 standard drinks for women and 4 drinks for men; placebo: no alcohol) were administered in counterbalanced order before bedtime. These led to bedtime average breath alcohol levels of up to 0.02% for the low doses and around 0.05% for the high doses. Autonomic and CV function were evaluated using electrocardiography, impedance cardiography, and beat-to-beat blood pressure monitoring. Results Presleep alcohol ingestion resulted in an overall increase in nocturnal heart rate (HR), suppressed total and high-frequency (vagal) HR variability, reduced baroreflex sensitivity, and increased sympathetic activity, with effects pronounced after high-dose alcohol ingestion (p’s < 0.05); these changes followed different dose- and measure-dependent nocturnal patterns in men and women. Systolic blood pressure showed greater increases during the morning hours of the high-alcohol dose night compared to the low-alcohol dose night and placebo, in women only (p’s < 0.05). Conclusions Acute evening alcohol consumption, even at moderate doses, has marked dose- and time-dependent effects on sleep CV regulation in adult men and women. Further studies are needed to evaluate the potential CV risk of repeated alcohol-related alterations in nighttime CV restoration in healthy individuals and in those at high risk for CV diseases, considering sex and alcohol dose and time effects.

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Differences in drinking patterns between men and women in Brazil

Brazilian Journal of Psychiatry ◽

10.1590/s1516-44462011000400010 ◽

2011 ◽

Vol 33 (4) ◽

pp. 367-373 ◽

Cited By ~ 23

Author(s):

Cynthia C Wolle ◽

Marcos Sanches ◽

Monica L Zilberman ◽

Raul Caetano ◽

Marcos Zaleski ◽

...

Keyword(s):

Alcohol Consumption ◽

Binge Drinking ◽

Negative Binomial ◽

Age Groups ◽

Negative Binomial Regression ◽

Treatment Programs ◽

Drinking Patterns ◽

Age And Gender ◽

Men And Women ◽

And Gender

OBJECTIVE: To examine sex differences in alcohol consumption according to age groups, and to assess gender and age effects on several aspects of alcohol consumption patterns. METHOD: Based on a Brazilian nationwide representative sample (n = 3,007), we analysed the differences in drinking patterns between genders. We also assessed the effects of gender, age, and gender by age interaction for alcohol consumption dimensions (frequent drinking, usual intake, binge drinking, and frequent binge drinking), using logistic and negative binomial regression models. RESULTS: Gender, age, and gender by age interaction had significant effects on the predictive models for all studied drinking patterns, except for the 'usual' dosage. The effect of gender on drinking patterns varies with age. While gender has a greater effect in older age groups, the difference between men and women decreased in the younger age groups. CONCLUSIONS: Gender convergence regarding alcohol use is a trend that might be influenced by environmental factors and should be addressed in prevention and treatment programs, as well as in public health policies.

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The Cochrane 2018 Review on Brief Interventions in Primary Care for Hazardous and Harmful Alcohol Consumption: A Distillation for Clinicians and Policy Makers

Alcohol and Alcoholism ◽

10.1093/alcalc/agz035 ◽

2019 ◽

Vol 54 (4) ◽

pp. 417-427 ◽

Cited By ~ 4

Author(s):

F R Beyer ◽

F Campbell ◽

N Bertholet ◽

J B Daeppen ◽

J B Saunders ◽

...

Keyword(s):

Primary Care ◽

General Practice ◽

Alcohol Consumption ◽

Brief Intervention ◽

Emergency Care ◽

Total Duration ◽

Brief Interventions ◽

Men And Women ◽

Harmful Alcohol ◽

The Impact

Abstract Aims An updated Cochrane systematic review assessed effectiveness of screening and brief intervention to reduce hazardous or harmful alcohol consumption in general practice or emergency care settings. This paper summarises the implications of the review for clinicians. Methods Cochrane methods were followed. Reporting accords with PRISMA guidance. We searched multiple resources to September 2017, seeking randomised controlled trials of brief interventions to reduce hazardous or harmful alcohol consumption in people attending general practice, emergency care or other primary care settings for reasons other than alcohol treatment. Brief intervention was defined as a conversation comprising five or fewer sessions of brief advice or brief lifestyle counselling and a total duration of less than 60 min. Our primary outcome was alcohol consumption, measured as or convertible to grams per week. We conducted meta-analyses to assess change in consumption, and subgroup analyses to explore the impact of participant and intervention characteristics. Results We included 69 studies, of which 42 were added for this update. Most studies (88%) compared brief intervention to control. The primary meta-analysis included 34 studies and provided moderate-quality evidence that brief intervention reduced consumption compared to control after one year (mean difference −20 g/wk, 95% confidence interval −28 to −12). Subgroup analysis showed a similar effect for men and women. Conclusions Brief interventions can reduce harmful and hazardous alcohol consumption in men and women. Short, advice-based interventions may be as effective as extended, counselling-based interventions for patients with harmful levels of alcohol use who are presenting for the first time in a primary care setting.

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