scholarly journals Dynamics of total lipids, total cholesterol, and total immunoglobulins in the blood serum of heifers of different breeds

2021 ◽  
Vol 37 ◽  
pp. 00023
Author(s):  
V Eremenko ◽  
E Rotmistrovskaya

The paper studies indices of lipid metabolism, immunoglobulins in blood serum of heifers of different breeds. Black-and-white, Simmental, Aberdeen-Angus, mongrel cattle was selected for this study. Each breed in the group consisted of 10 heads. The study of lipids dynamics in experimental heifers showed, the concentration of lipids gradually increased and by the 5th month reached the maximum values. By the end of the pregnancy on the 9th month, a decrease in the lipid concentration of all the compared breeds was observed. The study of cholesterol dynamics in experimental heifers showed that at 1 month old, the cholesterol level in experimental breed was approximately the same. These were the maximum values of total cholesterol over the entire pregnancy period. At 9 months old, the minimum values of total cholesterol were recorded before calving. The mixed bred analysis showed that a group of Aberdeen-Angus heifers and mongrel animals were characterized by increased blood cholesterol. The study of the dynamics of total immunoglobulins showed that at all periods of pregnancy there were differences in the level of total immunoglobulins in the blood serum of heifers of the studied breeds. By the end of the pregnancy, this indicator was increased. The results of mixed bred studies showed that the mongrel heifers were characterized by a slightly increased content of total immunoglobulins. During the pregnancy period, lower concentrations of lipids, cholesterol and immunoglobulins were typical for blackand- white, Simmental heifers.

2021 ◽  
Vol 4 (2) ◽  
pp. 80-85
Author(s):  
Irpan Ali Rahman ◽  
Endrian Mulyadi Justitia Waluyo ◽  
Shafira Aisyah Darmawan

Hypertension is an increase in systolic blood pressure above 140 mmHg and diastolic blood pressure above 90 mmHg. The number of hypertension sufferers has increased each year, in 2015 it reached 19,552, in 2016 it reached 24,750 and in 2017 it reached 38,057. In 2017 there were 115 hypertensive patients recorded in the report book that checked their health at the Sadananya Health Center. One of the causes of the high incidence of hypertension is cholesterol caused by the consumption of inappropriate food. One of the laboratory examinations to support hypertension diagnosis is blood cholesterol examination which can show excess cholesterol which makes hypertension difficult to control. To know the description of total cholesterol levels in hypertensive patients at the Sadananya Health Center. Quantitative descriptive, the population in this study were people with hypertension at the Sadananya Health Center. Sampling with accidental sampling, as many as 30 respondents. The cholesterol examination method used is CHOD-PAP. The results showed that blood pressure in respondents all had high blood pressure, namely >140/90 mmHg (100%), a high cholesterol level of 24 respondents (80%), blood pressure 140-150 who had high cholesterol as many 13 respondents, blood pressure 160-170 who had high cholesterol as much 6 respondents, blood pressure >180 who had high cholesterol as much 5 respondents. This study concludes that hypertensive clients have more high total cholesterol levels, which is as much as 80% and normal 20%. More hypertensive patients have high total cholesterol levels, which are 80% and 20% normal.


2021 ◽  
Vol 6 (2) ◽  
pp. 40-43
Author(s):  
Syupiarni Putri Waruwu ◽  
Joseph Partogi Sibarani ◽  
Saharnauli Janna Verawaty Simorangkir

Background: Cholesterol is a fat that does not dissolve easily in the blood. Most of the cholesterol in the blood is attached to specific protein carriers in the plasma in the form of lipoprotein complexes, which are soluble in water. Lipoprotein which carries cholesterol throughout the body. namely LDL (Low Density Lipoprotein) and HDL (High Density Lipoprotein). An increase in LDL in the body tends to form atherosclerosis. In contrast HDL cholesterol inhibits LDL oxidation so that atherosclerotic plaque formation does not occur. Obesity is one of the risk factors for atherosclerosis with manifestations of coronary heart disease. Handling of obesity has been done by many researchers and implemented. One ingredient from nature that serves as an alternative ingredient to lower blood cholesterol levels is avocado. Objective: To determine the effect of avocado administration on total blood cholesterol levels in the obese college students at the Medical Faculty of Nommensen HKBP University in 2019. Methods :This research is a pre-experimental study with a pre-post test design in one group. The sample was selected by purposive sampling method and obtained 20 obese students. Subjects consumed avocado juice every day for 14 days. Total cholesterol levels were measured before (day 0) and after (day 14) treatment. Results: The mean total cholesterol level of the subject's blood on the pretest examination was 188.10 mg / dL and the posttest examination was 180.05 mg / dL. There was a decrease in the average total blood cholesterol level of 8.05 mg / dl. Paired T-test showed that there was a non-significant decrease in mean total blood cholesterol level with a value of p = 0.068 (p <0.05). Conclusion: In this study there was no effect of avocado administration on total blood cholesterol levels in obese students.


Author(s):  
Rakesh Kumar ◽  
Binita Rani ◽  
Sonia Kumari ◽  
A K Jha

Considering the excellent bio-therapeutic benefits of Lactobacillus and Bifidobacterium, this study exploited the probiotic characteristics of Lactobacillus acidophilus-015, Lactobacillus casei-297 and Bifidobacterium bifidum-229 strains with natural prebiotic substances viz. banana powder, malto-dextrin and honey to produce synbiotic food formulations and to study the effect of feeding their on the cholesterol level (mg/dl) of albino rats. On the basis of the preliminary investigation, synbiotic products with 2% banana powder, with 2% malto-dextrin, with 3% honey and synbiotic product with 2% each of, banana powder and malto-dextrin and 1% of honey were selected for the investigation of the total cholesterol, HDL-cholesterol and non-HDL cholesterol. The products showed a significant decrease in total cholesterol level, however the control group receiving the cholesterol rich laboratory diet showed a significant increase (P LESS THEN 0.01) in the total cholesterol after 45 days of feeding. There was 25.81 to 45.05% reduction of serum cholesterol was observed in case of feeding synbiotic formulations. Increase in the HDL-cholesterol and decrease in the non-HDL cholesterol were also significant. Therefore, synbiotic formulation with all these three natural prebiotic have enhanced ability to decreased down the blood cholesterol level.


2018 ◽  
Vol 6 (2) ◽  
Author(s):  
Magdalena Talumewo ◽  
Murniati Tiho ◽  
Michaela E. Paruntu

Abstract: Unhealthy eating habit could lead to obesity. Obesity is always associated with the increase of blood cholesterol level (hypercholesterolemia). Increased cholesterol level is a risk factor of the death in young adult. This study was aimed to obtain the profile of total blood cholesterol levels among students of Faculty of Medicine Sam Ratulang University with body mass index (BMI) ≥23 kg/m2. This was a descriptive study. Samples were obtained by using total sampling method. There were 53 students involved in this study consisted of 22 males and 31 females. The results showed that 23 students (43.4%) had normal total cholesterol levels and 30 students (56.6 %) had low total cholesterol levels. Conclusion: More than half of the students of Faculty of Medicine Sam Ratulangi University with BMI ≥23 kg/m2 had low total cholesterol level.Keywords: total cholesterol, BMI ≥23 kg/m2. Abstrak: Kebiasaan makan yang tidak sesuai dengan kaidah sehat dapat mengakibatkan obesitas. Kondisi obesitas selalu dikaitkan dengan peningkatan kadar kolesterol dalam darah atau hiperkolesterolemia. Peningkatan kadar kolesterol merupakan factor risiko penyebab kematian di usia dewasa muda. Penelitian ini bertujuan untuk mengetahui gambaran kadar kolesterol total darah pada mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi dengan indeks massa tubuh (IMT) ≥23 kg/m2. Jenis penelitian ialah deskriptif. Sampel diperoleh dengan metode total sampling. Penelitian ini diikuti oleh 53 orang subyek penelitian yang terdiri dari 22 orang laki-laki dan 31 orang perempuan. Hasil penelitian mendapatkan 23 orang (43,4%) memiliki kadar kolesterol total normal dan 30 orang (56,6%) memiliki kadar kolesterol total rendah. Simpulan: Lebih dari setengah mahasiwa Fakultas Kedokteran Universitas Sam Ratulangi dengan IMT ≥23 kg/m2 memiliki kadar kolesterol total rendah.Kata kunci: kolesterol total, IMT ≥23 kg/m2


2016 ◽  
Vol 5 (3) ◽  
Author(s):  
Putri Mira Magistri ◽  
Rismawati YaswiR ◽  
Yustini Alioes

AbstrakMasyarakat menggunakan berbagai cara pengolahan sebelum mengonsumsi telur yang dapat berpengaruh terhadap kadar zat gizi yang terkandung didalamnya, termasuk kadar kolesterol dalam telur yang juga akan mempengaruhi kadar kolesterol dalam darah. Tujuan penelitian ini adalah menentukan pengaruh pemberian berbagai olahan telur terhadap kadar kolesterol total darah mencit. Penelitian menggunakan 24 ekor mencit (Mus musculus) jantan albino umur 3 – 4 bulan dengan berat badan sekitar 30 – 40 gram. Jenis kandang yang digunakan adalah kandang kotak (box) sebanyak 24 unit dengan ukuran 28x30x20 cm. Metode yang digunakan ialah eksperimen dengan Rancangan Acak Lengkap (RAL) terdiri dari 6 unit perlakuan, yaitu unit perlakuan K (Kontrol), unit perlakuan A (telur mentah), unit perlakuan B (telur goreng), unit perlakuan C (telur rebus), unit perlakuan D (telur setengah matang) dan unit perlakuan E (telur asin). Dosis perlakuan adalah 1,56ml/20gram berat badan/mencit dan masing-masing perlakuan diulang 4 kali. Parameter yang diukur adalah kadar kolesterol total darah mencit. Hasil analisis keragaman menunjukan bahwa pemberian berbagai olahan telur memberikan pengaruh berbeda sangat nyata (P<0.01) terhadap kadar kolesterol total darah mencit. Berdasarkan hasil penelitian dapat disimpulkan bahwa rerata kadar kolesterol total darah mencit setelah diberikan berbagai olahan telur adalah telur mentah 106.96 mg/dl, telur goreng 143.53 mg/dl, telur rebus 194.50 mg/dl, telur setengah matang 180.91 mg/dl, dan telur asin 158.27 mg/dl.Kata kunci: olahan telur, kadar kolesterol total darah, mencit AbstractPeople use various methods of processing before consumption eggs which can affect the levels of nutrients contained in, including cholesterol content which can also affect the levels of total cholesterol in blood. The objective of this study was to determine the effect of giving a variety of processed egg on total cholesterol levels of mice. The experiment used 24 male albino mice (Mus nusculus) age 3 – 4 months old with 30 – 40 grams of body weight. The den used was 24 units of box with size of 28x30x20 cm. The experiment used Completely Randomized Design (CRD) consist of 6 treatment units which was K (control), A (raw egg), B (fried egg), C (boiled egg), D (soft-boiled egg), and E (salted egg). The dosage was  1.56 ml/20 grams of body weight/mice and 4 replication for each treatment units. The parameter measured was total blood cholesterol level of mice.  Results of analysis of variance showed that giving of a variety of processed egg gave highly  significant  effect (P <0.01) on total blood cholesterol levels of mice. Based on the results of this study, it can be concluded that the average total blood cholesterol levels of mice after giving of various preparations of eggs is as follows: raw eggs 106.96 mg / dl, fried eggs 143.53 mg / dl, boiled eggs 194.50 mg / dl, soft-boiled eggs 180.91 mg / dl, and salted egg 158.27 mg / dl..Keywords: processed egg, total blood cholesterol level,  mice


2018 ◽  
Vol 69 (8) ◽  
pp. 2025-2028
Author(s):  
Ana Simona Drochioi ◽  
Dan Cristian Moraru ◽  
Ilie Cristian Drochioi ◽  
Magdalena Iorga ◽  
Eduard Crauciuc ◽  
...  

The liver is the main metabolic organ, having complex physiological and biochemical roles, many of these functions being in a close relationship. It is also well known that hepatitis C virus infection is associated with changes in lipid metabolism. This is evident in liver dysfunctions, when liver functions are disturbed simultaneously. The aim of this study is to evaluate the effect of antiviral therapy on serum lipid level in patients with viral hepatitis C before and at the end of the 48 weeks of treatment compared patients treated with Interferon vs Interferon + Ribavirin and relation with sustained virological response, from North East Romania. We evaluated patients hospitalized in Emergency Hospital for Children St. Mary Iasi between 2009-2017. The result of our study show that the mean age of patients from goup 1 was 11.85�3.65 years, vs 11.5�3.1 years in group 2 (p=0.171). We found changes in cholesterol metabolism in both groups of patients, increases in total cholesterol level, 21.43% of patients in the group 1 vs 32.3% in goup 2 (p=0.258) and decreases 17.86% vs 14.7% (p=0.131). At initiation of antiviral therapy mean serum cholesterol level were 155.78�36.30 mg/dL, in group 1 vs 149.88�47.22 mg/dL, for group 2. At 48 weeks of treatment in the both goups revealed significantly decreased of total cholesterol levels 136.46�41.63mg/dL, for group 1 vs 109.26�41.05, for patients in group 2 (p=0.003). Triglycerides, HDL cholesterol and LDL cholesterol did not show significant changes in the patients of the two groups. Total cholesterol level after antiviral therapy were significantly different between patients who achieved SVR and non SVR (p=0.014), group 1 vs (p=0.001), group 2. Total serum cholesterol level showed significant changes during the antiviral therapy in both monotherapy and combination therapy group.


Author(s):  
Dwintha Lestari

Objective: The objective of this research was to evaluate reduction of blood cholesterol level by fraction extracts of binahong (Anredera cordifolia) on male Wistar rats. Methods: The rats were given high fat food every day for 3 months and pure cholesterol on week 0, 3, 7 and 11.  After that each binahong fraction (n-hexane fraction, ethyl acetate fraction and water fraction) with doses of 50 mg/kg bw, 100 mg/kg bw, 200 mg/kg bw were given orally for 3 weeks and observed for lipid profile on day 21.   Results: The result showed that n-hexane, ethyl acetate and water fractions of binahong leaves decreased total cholesterol, triglyceride and LDL level, and did not influence the HDL level. Meanwhile statin decreased total cholesterol, triglyceride and LDL level, and increased HDL level. Conclusion: Ethyl acetate fraction of binahong leaves significantly reduced total cholesterol level, triglycerides, LDL level compared to negative control group (p< 0.05) and had no influence in HDL level. Keywords: Atherosclerosis, Anredera cordifolia, cholesterol


e-CliniC ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Jason G. Rupang ◽  
Sarah M. Warouw ◽  
Nurhayati Masloman

Abstract: Obesity is a disorder or disease that characterized by excessive accumulation of adipose tissue. Obesity is a world health problem and increasingly common in various countries. The most common causes of obesity are genetic factors, physical inactivity, and unhealthy diet. Obesity and high total cholesterol level in adolescent cause various chronic diseases, such as diabetes mellitus, coronary heart disease, and cerebrovascular disease. The aim of this study is to investigate the correlation between total cholesterol level and blood pressure in obese adolescents. This is an analytical observational study, using cross sectional design. Samples were chose using consecutive sampling technique in two junior high schools and senior high schools in Tomohon Tengah district, Tomohon City. Samples are adolescent age 13-15 years old, which was selected through anthropometric examination, blood pressure measurement, and blood sample collection. The result from 38 samples showed that there is no correlation between total cholesterol level with blood pressure, both systolic blood pressure (p=0.867) and diastolic blood pressure (p=0.627). Conclusion: There is no correlation between total blood cholesterol and blood pressure (both systolic and diastolic). Parents should pay more attention to the children’s health and diet to prevent a prolonged obesity.Keywords: obesity, total cholesterol, blood pressure, adolescent Abstrak: Obesitas atau kegemukan adalah suatu kelaianan atau penyakit yang di tandai oleh penimbunan jaringan lemak dalam tubuh secara berlebihan. Obesitas merupakan masalah kesehatan dunia yang semakin sering ditemukan di berbagai Negara. Penyebab paling sering menyebabkan obesitas adalah faktor genetik, kurangnya aktifitas fisik dan pola makan yang tidak sehat. Obesitas dan kolesterol total yang berlebih pada remaja merupakan penyebab terjadinya berbagai penyakit kronik termasuk hipertensi, diabetes melitus, penyakit jantung koroner, dan penyakit serebrovaskular. Penelitian ini bertujuan untuk mengetahui hubungan antara kadar kolesterol total dengan tekanan darah pada remaja obes. Jenis penelitian ialah analitik observasional dengan rancangan potong lintang dengan teknik consecutive sampling pada dua SMP dan dua SMA di Kecamatan Tomohon Tengah, Kota Tomohon pada bulan September hingga November 2016. Sampel pada penelitian adalah remaja yang berusia 13-15 tahun. Data yang diambil melalui pemeriksaan antropometri, pemeriksaan tekanan darah, dan pengambilan sampel darah. Hasil penelitian dari masing - masing 38 sampel menunjukkan tidak terdapat hubungan antara kadar kolesterol total dengan tekanan darah sistolik (p=0.867) dan tekanan darah diastolik (p=0.627).Simpulan: Tidak terdapat hubungan antara kadar kolesterol total dengan tekanan darah (TDS&TDD). Orang tua diharapkan lebih memperhatikan kesehatan dan pola makan untuk mencegah terjadinya obesitas yang berkepanjangan. Kata kunci: obesitas, kolesterol total, tds, tdd, remaja


Author(s):  
Tungki Pratama Umar ◽  
Mariana Mariana

Background: Hypertension is the main problem worldwide. It has strong relationship with other component of metabolic syndrome, namely dyslipidemi. Authors are analyzing the correlation between total cholesterol level and blood pressure in the hypertensive patient at Kalidoni Primary Health Center, Palembang, Indonesia.Methods: This was a cross-sectional study involving 82 adult hypertensive patients. Data were collected from the medical record of patients who are visiting Kalidoni Primary Health Center in December 2019-January 2020. Demographic data, blood pressure, and total cholesterol level were gained. Obtained data are analyzed descriptively (frequency distribution) and analytically (correlation using Pearson or Spearman method).Result: Significant positive correlations were observed between total cholesterol level and systolic blood pressure (r=0.509, p=0.000) in addition to body weight and diastolic blood pressure (r=0.279; p=0.011).Conclusion: Blood cholesterol level had a significant correlation with moderate strength for determining systolic blood pressure level in hypertensive patients.


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