Stabilization of Canine Pelvic Osteotomies with AO/ASIF Plates and Screws

1988 ◽  
Vol 01 (01) ◽  
pp. 52-57 ◽  
Author(s):  
C.A. Hunt ◽  
A S. Litsky
Keyword(s):  
Dynamic Compression ◽  
Unit Length ◽  
Pelvic Osteotomy ◽  
The Body ◽  
Stable Fixation ◽  
Holding Power ◽  
Mixed Breed ◽  
Significant Difference ◽  
Cancellous Screws

Stabilization of pelvic osteotomy with a 2.7 mm dynamic compression plate (DCP) for the treatment of hip dysplasia, was performed in 42 operations in 27 dogs. Screw loosening was observed in 11 osteotomies (26%), plate bending in six cases (14%) and plate breakage in two cases (4%). An in vitro experiment using the pelvic bones of young mixed breed dogs showed no significant difference in the holding power of AO/ASIF 2.7 mm cortical, 3.5 mm cortical and 3.5 mm fully threaded cancellous screws in the body of the ilium. The 2.7 mm DCP has an advantage over the 3.5 DCP in stabilizing pelvic osteotomy because it allows more screws to be used per unit length of plate, which possibly results in a more stable fixation.

scholarly journals Effect of Nursing Guidelines on Coping of Infertile Couples Undergoing In Vitro Fertilization

2020 ◽  
Vol 2 (2) ◽  
pp. 11
Author(s):  
Gehan S. Abdelgelel ◽  
Shadia H. Muhsib ◽  
Mona H. Abdelaal ◽  
Randa M. Ibrahim
Keyword(s):  
In Vitro Fertilization ◽  
Coping Strategies ◽  
Unprotected Sex ◽  
The Body ◽  
University Hospital ◽  
Vitro Fertilization ◽  
Significant Difference ◽  
Infertile Couples ◽  
Nursing Guidelines

Context: Infertility is defined as not being able to conceive after one year of unprotected sex. In vitro fertilization (IVF) is a process of fertilization where an ovum is combined with sperm outside the body, in vitro. In vitro fertilization (IVF) is psychologically and emotionally stressful. Coping strategies are needed to master, tolerate, reduce, or minimize stressful events. Aim: This study aimed to evaluate the effect of nursing guidelines on coping of infertile couples' undergoing In Vitro Fertilization. Methods: A quasi-experimental research design was utilized to achieve the aim of this study. This study conducted at the assisted reproductive technology unit of Ain shams Maternity University Hospital on a convenient sample of 98 couples undergoing fertility treatments. Two tools were used for data collection; the first tool was a structured interviewing questionnaire to assess the couple's socio-demographic data, obstetric history, the couple's knowledge regarding in vitro fertilization. The second tool was ways of coping scale (WQS) to assess coping strategies among the infertile couple. Results: There is no statistically significant difference between couples in both groups according to their knowledge and their coping strategies to IVF before the implementation of nursing guidelines (p> 0.05). In contrast, there is a highly statistically significant improvement in knowledge and coping strategies of couples on the study group compared to control group couples after implementation of nursing guidelines(p<0.001). Conclusion: The finding of the current study supported the hypothesis, which stated that the infertile couples who will expose to the nursing guidelines, will exhibit improved coping strategies to IVF compared to the controls. The study recommended the application of nursing guidelines at the IVF unit of Ain Shams Maternity University Hospital and other settings for IVF treatment as routine care to improve infertile couples' coping strategies.

A MODEL OF TYPE I COLLAGEN FIBRILLOGENESIS BASED ON DIFFUSION LIMITED AGGREGATION

1995 ◽  
Vol 03 (04) ◽  
pp. 1033-1039
Author(s):  
JOHN PARKINSON ◽  
KARL E. KADLER ◽  
ANDY BRASS
Keyword(s):  
Type I Collagen ◽  
Unit Length ◽  
The Body ◽  
Biological Macromolecules ◽  
Type I ◽  
Structural Protein ◽  
Diffusion Limited Aggregation ◽  
Mass Unit ◽  
Diffusion Limited

The development of shape and form is intrinsic to the structure and function of many biological macromolecules including tubulin, actin and collagen. Type I collagen is a major structural protein in the body, providing mechanical strength for tissues such as bone and skin. It is present in the form of fibrils which display a regular banding pattern known as D-periodicity (where D = 67 nm). Type I collagen is a long rod-like molecule (300 nm ×1.5 nm) consisting of a triple helix formed from three polypeptide chains. In vivo and in vitro studies have shown that collagen molecules self-assemble in a regular D-staggered array to form striated fibrils. Further studies have shown that the process, termed fibrillogenesis, is entropy driven. A model based on diffusion limited aggregation was used to investigate the properties of rod self-assembly. This simple model reproduced several experimentally observed features of collagen fibril morphology including a linear mass/unit length profile and a preference for tip growth.

scholarly journals Pengaruh Infusa Biji Buah Pinang (Areca catechu) Terhadap Tingkat Kematian dan Morfometri Cacing Dewasa Ascaridia galli Secara In Vitro

2019 ◽  
Vol 37 (2) ◽  
pp. 166
Author(s):  
Wida Wahidah Mubarokah ◽  
Kurniasih Kurniasih ◽  
Wisnu Nurcahyo ◽  
Joko Prastowo
Keyword(s):  
Mortality Rate ◽  
Aqueous Extract ◽  
Saline Water ◽  
The Body ◽  
Ascaridia Galli ◽  
Body Width ◽  
Significant Difference ◽  
Areca Catechu ◽  
Crude Aqueous Extract

The study evaluates in vitro effects of Areca catechu crude aqueous extract  as anthelmintics on Ascaridia galli adult mortality rate and morphometry. Naturally infected chickens were collected from slaughtered chickens at local slaughterhouses in Yogyakarta. Chicken’s intestines were carefully examined and transported to the Parasitological Laboratory of Gadjah Mada University, Yogyakarta. Ascaridia galli were collected from intestines (including duodenum, jejunum, and ileum) and put into a petri dish containing 0.62% saline water. There were 60 A. galli in each concentration of Areca catechu crude aqueous extract. Investigation on mortality rate of adult worms at various concentration and observation as well as differences in A. galli morphometry and mortality rate were analyzed using analysis Anova. The figures of the parasites or the parts of the parasites were captured using camera Lucida and then they were measured using both micrometer and curvimeter. The morphology of the parasites was identified to find out their morphometric characteristics.The results of morphometric observation of the A. galli showed that there was a significant difference in the body width and the vulva length of the females and in the body width, the esophageal length and the esophageal width of the males.This research disclosed that Areca catechu crude aqueous extract significantly affected the mortality rate of adult A.galli at various concentration. This research observed that the best concentration to kill the adult worms was 25% Areca catechu crude aqueous extract.

Hypothalamic response to leptin changes during a hormonally induced estrous cycle in rats

2006 ◽  
Vol 1 (2) ◽  
pp. 221-234 ◽  
Author(s):  
Kajsa Sjöholm ◽  
Björn Carlsson ◽  
Lena Carlsson
Keyword(s):  
Food Intake ◽  
Estrous Cycle ◽  
Primary Response ◽  
The Body ◽  
Leptin Resistance ◽  
Cytokine Signaling ◽  
Mrna Levels ◽  
Significant Difference ◽  
Cyclic Feeding

AbstractThe leptin system regulates body fat mass through a feedback loop between adipose tissue and the hypothalamus. To test if leptin responsiveness may be regulated we assayed hypothalamic response to leptin during the estrous cycle; when changes in food intake are known to occur. Immature rats were treated with pregnant mare’s serum gonadotropin (PMSG) to induce synchronized follicular development, ovulation and corpus luteum formation. Leptin response was estimated by measuring the in vitro induction of tis11, a primary response gene activated by STAT3-dependent cytokines in hypothalamic explants after leptin stimulation. In addition, mRNA levels of the suppressor cytokine signaling-3 (SOCS-3), a possible mediator of leptin resistance, were analyzed. Serum leptin levels did not change between days 2 and day 3 (corresponding to proestrus and estrus, respectively) but the response to leptin was higher on day 2 than on day 3 (p=0.05). Food intake displayed a tendency towards downregulation between day 1 and day 2 (p=0.057), and a tendency towards upregulation between day 2 and day 3 (p=0.072), although the body weight increased on day of the study (p<0.0001). There was no significant difference in hypothalamic expression of SOCS-3 between day 2 and day 3. In conclusion, we have shown that leptin responsiveness changes during a hormonally induced estrous cycle in rats. Our data suggest that a change in the hypothalamic response to leptin may cause the cyclic feeding behavior seen in rats.

scholarly journals The Antibacterial Effect of Ethanol Edamame Seeds (Glycine Max (L) Merril) Extract to E.coli Bacteria

2020 ◽  
Vol 6 (3) ◽  
pp. 137
Author(s):  
Diayu Putri Akhita ◽  
Edy Junaidi ◽  
Septa Surya Wahyudi
Keyword(s):  
Average Diameter ◽  
Inhibition Zone ◽  
Negative Control ◽  
The Body ◽  
Control Group ◽  
Control Group Design ◽  
Significant Difference ◽  
Post Test ◽  
The Times

Abstract Infectious diseases can occur in all parts of the body. One of the causes infection in humans is Eschericiae coli bacteria. Eschericiae coli is a rod-shaped bacteria, a gram negative bacteria, facultative aerobics and classified family member of Enterobacteriaceae from the Gammaproteobacteria class. Along the times, E.coli bacteria have resistent to some antibiotics. So we need a new alternative. There is a antibacterial substance in the isoflavon group contained in edamame. Genistein is a main isoflavon in edamame that have antiinflammation, antibacterial, and antioxidant effects. The purpose of this study was to determine is there any antibacterial effects in ethanol edamame seeds extract to E.coli bacteria. This study used a true experimental research design in vitro with a post test only control group design.  The average diameter results of the inhibition zone were analyzed using the Kruskal-Wallis method and obtained p = 0.001 which means there are significant differences in at least two groups. After that, the Mann Whitney post hoc test was conducted and a significant difference was found in the positive and negative control groups for all groups but there was no difference in the treatment group, both groups K1, K2 and K3 for all groups. Keywords : Edamame, Antibacterial, E.coli

scholarly journals The Effects of 1-Beta-D-Arabinofuranosylcytosine and Adriamycin on the Chromosomes of Cultured Human Lymphocytes

2021 ◽  
Author(s):  
◽  
Keith Lyle McLea
Keyword(s):  
Chromosome Aberrations ◽  
Treatment Time ◽  
Unit Length ◽  
Human Lymphocytes ◽  
Sister Chromatid Exchanges ◽  
Significant Difference ◽  
Different Types ◽  
Pass Through ◽  
Chromatid Aberrations

<p>A study of chromosome aberrations induced by 1-Beta-D-arabinofuranosylcytosine (Ara C) and Adriamycin (AM) in the chromosomes of cultured human lymphocytes was made. There were significant increases in the frequency of aberrations with increasing concentrations of both Ara C (2.5, 5.0 and 10.0 mug/ml) and AM (0.01, 0.05, 0.10 and 0.15 mug/ml). The frequency of aberrations induced by both drugs also showed a 'levelling off' above particular concentrations. For Ara C the effect of increasing treatment time was also studied. The frequency of aberrations increased significantly with increasing treatment times (2, 3 and 4 hrs) although no 'levelling off' in the number of aberrations was observed. The relationship between the frequency of the different types of aberrations induced by Ara C and AM was studied. AM allowed for a study of the relative frequency of chromosome versus chromatid aberrations and fragment versus exchange aberrations. There were always more fragments than exchanges, and always more chromatid aberrations than chromosome aberrations. Aberrations induced by Ara C were all of the chromatid fragment type. A study was made of the distribution of inter- and intra-chromosomal aberrations in relation to light and dark G banded chromosomes. Both drugs induced more aberrations in the light G bands than the dark G bands. Both drugs showed distinct clustering of aberrations in some regions of the chromosomes (hotspots), although the location of AM induced hotspots was different from the location of those induced by Ara C. The distribution of AM induced chromatid aberrations was different from the distribution of the chromosome aberrations, as were the distributions of the fragment and exchange aberrations. The different types of aberrations also differed in the number of AM induced aberrations per unit length between the p and q arms. There were more aberrations per unit length in the p arm than in the q arm for exchanges, whereas for fragments and chromosome aberrations the reverse was true. For chromatid aberrations, there was no significant difference in the number of aberrations per unit length between the p and q arms. Inter-individual differences in the frequency of AM induced aberrations were observed in the .AM dosage experiments. Also there was a suggestion that the distribution of Ara C induced aberrations was different for different donors. AM increased the frequency of sister chromatid exchanges. Comparable results were not sought for Ara C because after cells were exposed to Ara C they did not pass through an S phase of the cell cycle, as is the case for cells exposed to AM. The relevance of the present in vitro studies to cancer chemotherapy is briefly discussed.</p>

A Biomechanical Comparison of Composite Fixation and Veterinary Acetabular Plates for Stabilization of Acetabular Osteotomies in Dogs Loaded in Three-Point-Bending Fashion

1998 ◽  
Vol 11 (03) ◽  
pp. 152-157 ◽  
Author(s):  
D. D. Lewis ◽  
J. B. Madison ◽  
L. L. Blaeser ◽  
O. I. Ianz
Keyword(s):  
Yield Point ◽  
In Vitro Study ◽  
Maximum Load ◽  
Fixation Method ◽  
Three Point Bending ◽  
Mixed Breed ◽  
Significant Difference ◽  
Biomechanical Comparison ◽  
In Vitro Comparison

SummaryAn in vitro study comparing the biomechanical performance and accuracy of reduction for two methods of acetabular osteotomy repair in the dog is presented. Pelves were harvested from five adult mixed breed dogs weighing 25-30 kg. On e hemipelvis from each dog was repaired with the composite fixation and the contralateral hemipelvis was repaired with a 2.0 mm six hole veterinary acetabular plate. Eac h hemipelvis was loaded in a threepoint- bending fashion at a rate of 5 mm/min. An extensometer was placed over the dorso-medial surface of the acetabular osteotomy during loading. Reduction was significantly better for hemipelves stabilized with the composite fixation when compared to hemipelves stabilized with the 2.0 mm six hole veterinary acetabular plate. There was not a significant difference in bending stiffness, distractional stiffness, yield point and maximum load between repair groups.An in vitro comparison was made between a composite fixation method and acetabular plates for the stabilisation of acetabular osteotomies.

scholarly journals The use of a rat model to evaluate the in vivo toxicity and wound healing activity of selected Combretum and Terminalia (Combretaceae) species extracts

2010 ◽  
Vol 77 (1) ◽  
Author(s):  
Peter Masoko ◽  
Jackie Picard ◽  
Jacobus N. Eloff
Keyword(s):  
Wound Healing ◽  
Chronic Wounds ◽  
Fungal Infections ◽  
Tissue Injury ◽  
Healing Process ◽  
The Body ◽  
Wound Healing Process ◽  
Leaf Extracts ◽  
Significant Difference

Wound healing is a fundamental response to tissue injury and several natural products have been shown to accelerate the healing process. The present study was undertaken to determine the safety and efficacy of the topical treatment of acetone leaf extracts of Combretum imberbe, Combretum nelsonii,Combretum albopuntactum and Terminalia sericea based on their in vitro antimicrobial activity. Four circular full-thickness skin wounds were made on the backs of eight anaesthetised Wistar rats using aseptic techniques. The treatments were administrated topically using 10% and 20% concentrations of each extract in aqueous cream in separate treatments. Indications of erythema, exudate, crust formation,swelling and ulceration were used to determine the wound healing process. All of the wounds closed completely within 17 days. Throughout the experiment, a subcutaneous probe was used to determine that the body temperature and body weight of the rats were within the normal range. C. imberbe and C. nelsonii extracts accelerated wound healing, but there was no significant difference in wound contraction using 10% and 20% concentrations of the extracts in cream. The results also showed the potential usefulness of this model to measure accelerating wound healing.The extracts could perhaps overcome defects associated with healing failure in chronic wounds and prevent secondary bacterial and fungal infections.

scholarly journals Potensi Vermisidal Infusa Biji Buah Merah (Pandanus conoideus), Rumput Kebar (Biophytum petersianum) dan Kulit Buah Pinang (Areca catechu) terhadap Ascaridia galli secara In Vitro

2022 ◽  
Vol 11 (3) ◽  
pp. 269
Author(s):  
Rizki Arizona ◽  
Dwi Nurhayati ◽  
Abdul R. Ollong ◽  
Priyo Sambodo
Keyword(s):  
Body Length ◽  
The Body ◽  
Betel Nut ◽  
Ascaridia Galli ◽  
Control Solution ◽  
Significant Difference ◽  
Areca Catechu ◽  
Materials Used ◽  
And Control

Abstract This study aimed to determine the vermicidal potency of the infusion of Buah Merah seeds, Rumput Kebar and betel nut peels against Ascaridia galli in chickens and body length of male and female A. galli. Dry test materials (5%, 10% and 15% for each concentration) were immersed in 100 ml of distilled water and incubated at 90 °C for 15 minutes. The solution was filtered using filter paper, and the filtrate was used in the treatment. Three active worms that obtained directly from chicken intestines were placed in 15 cm Petri dishes containing 25 ml of each treatment and control solution. Five replications were performed for each treatment. Observations were made 8 hours after treatment for paralysis and worm death. Measurements of the body length were made from the anterior end to the posterior end of the worm using a ruler. Observational data were processed using Anova, the significant difference was continued by the Tukey HSD test (P<0.05) with SPSS 16.0. Conclusion: all the materials used in this study have potential as anthelmintics against A. galli and the highest dose of rumput Kebar infusion is the best vermicidal. The body length of female A. galli is longer than of the male. Keywords: Betel nut peels; Buah merah seeds; Infusion; Rumput kebar; Vermicidal   Abstrak Penelitian ini bertujuan untuk mengetahui potensi vermisidal infusa biji Buah Merah, Rumput Kebar dan kulit buah Pinang terhadap Ascaridia galli pada ayam dan ukuran panjang tubuh A. galli jantan dan betina. Bahan uji kering (5%, 10% dan 15% untuk masing-masing konsentrasi) direndam dalam 100 ml aquadestillata dan diinkubasi pada suhu 90 °C selama 15 menit. Larutan disaring menggunakan kertas saring, dan filtratnya digunakan dalam perlakuan. Tiga cacing yang aktif bergerak yang diperoleh langsung dari usus ayam, ditempatkan dalam cawan Petri berukuran 15 cm yang berisi 25 ml masing-masing larutan perlakuan dan kontrol. Dilakukan lima ulangan untuk setiap perlakuan. Pengamatan dilakukan 8 jam setelah perlakuan terhadap paralisis dan kematian cacing. Pengukuran dilakukan dari ujung anterior ke ujung posterior cacing menggunakan penggaris. Data hasil pengamatan diolah menggunakan Anova, perbedaan nyata dilanjutkan dengan uji Tukey HSD (P<0,05) dengan SPSS 16.0. Kesimpulan: seluruh bahan yang digunakan pada penelitian ini memiliki potensi sebagai anthelmintik terhadap A. galli dan dosis tertinggi infusa rumput Kebar merupakan vermisidal yang paling baik. Panjang tubuh A. galli betina lebih panjang dari pada jantan. Kata kunci: Biji buah merah; Infusa; Kulit buah pinang; Rumput kebar; Vermisidal

scholarly journals Comparing the In Vitro Stiffness of Straight-DCP, Wave-DCP, and LCP Bone Plates for Femoral Osteosynthesis

2013 ◽  
Vol 2013 ◽  
pp. 1-6
Author(s):  
José Ricardo Lenzi Mariolani ◽  
William Dias Belangero
Keyword(s):  
Dynamic Compression ◽  
Femoral Fractures ◽  
Plate Versus ◽  
Wave Form ◽  
Stable Model ◽  
Structural Stiffness ◽  
Femur Fractures ◽  
Significant Difference ◽  
Compression Plate

The objective of this study was to compare the Locking Compression Plate (LCP) with the more cost-effective straight-dynamic compression plate (DCP) and wave-DCPs by testing in vitro the effects of plate stiffness on different types of diaphyseal femur fractures (A, B, and C, according to AO classification). The bending structural stiffness of each plate was obtained from four-point bending tests according to ASTM F382-99(2008). The plate systems were tested by applying compression/bending in different osteosynthesis simulation models using wooden rods to simulate the fractured bone fragments. Kruskal-Wallis test showed no significant difference in the bending structural stiffness between the three plate models. Rank-transformed two-way ANOVA showed significant influence of plate type, fracture type, and interaction plate versus fracture on the stiffness of the montages. The straight-DCP produced the most stable model for types B and C fractures, which makes its use advantageous for complex nonosteoporotic fractures that require minimizing focal mobility, whereas no difference was found for type A fracture. Our results indicated that DCPs, in straight or wave form, can provide adequate biomechanical properties for fixing diaphyseal femoral fractures in cases where more modern osteosynthesis systems are cost restrictive.

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