:
The coronavirus disease 2019 (COVID-19) first outbreak in Wuhan, China, and the infection is intense
worldwide. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for COVID-19. The World
Health Organization (WHO) confirmed total deaths had noted 4.20% globally (March 21, 2020). Between the intervals of
four months (July 21, 2020), confirmed total deaths had recorded 4.17%, globally. In India, 909 confirmed cases and 19
deaths were reported by Health and Family Welfare, Government of India, March 28, 2020. Between the intervals of 123
days In India, 1638870 confirmed cases and 35684 deaths. COVID-19 can potentially spread from person to person through
direct contact or respiratory droplets from coughing and sneezing. The most common symptoms are fever, dry cough,
difficulty in breathing, and fatigue. A pregnant mother with COVID-19 has fewer chances to transfer this infection of her
newborn babies. Children have less affected than an adult. A specific antiviral drug or vaccine has not been developed to
cure the disease. Chloroquine, hydroxychloroquine, lopinavir, ritonavir, nafamostat, nitazoxanide, and remdesivir have
effective drugs to treat COVID-19. Many vaccine candidates are under pre-clinical and clinical studies. In this review, we
highlight the epidemiology, sign-symptoms, pathogenesis, mode of transmission, and effects of a pregnant mother with
newborns, children, prevention, and drugs affective to COVID-19.