Over Humane en A-Humane Taal.

1980 ◽  
Vol 8 ◽  
pp. 185-199
Author(s):  
A. Angevaare

I want to distinguish between two fundamental modes of being. The primary mode is typified by activities that are absolutely unique and at the same time absolutely universal, such as being born, living, growing up, eating, working, playing, loving, dying. These activities originate from my undivided being. The secondary mode is typified by activities that are socially and culturally determined. I perform these as a person (personamask). When I act as an individual I cannot be replaced by someone else; it is impos-sible to measure these activities (they have no 'market-value') and I don't learn them in the literal sense - all this in contradistinction to my social or role-activities. Accordingly I want to distinguish between human and a-human language (the terms have no ethical implications), or between the I-mode and the YOU-mode and between two resulting ways of speaking. I can speak as an individual and as a person and these ways of speaking are typified in compliance with the above-mentioned characteristics. Human language is perhaps a somewhat neglected phenomenon in linguistics. An allied phenomenon is the tendency in our culture to transfer individual speaking to the domain of speaking as a person. When I mark off these distinctions against certain dimensions in socio-pragmalinguistics I find that orientation on the illocutionary effect plays a prominent part in personal speaking. Splitting up myself into speaker and hearer I project myself into the hearer, planning my formulations from his point of view to make myself understood. When I speak as an individual I am not primarily focused on communication and the illocutionary effect. Making myself understood to an actual or potential hearer is subordinate to the adequate expression of what lies on my mind. Moreover, when I speak as a person I am often focused on the perlocutionary effect, that I can try to act upon by means of conditional relevance and selection of the correct code. The options I have between formal varieties are in fact to be explained in terms of the directive function of language. When I speak as an individual the idea of communicative interaction recedes into the background and the issue of the perlocutionary effect is left out. Concerning the substance of my speaking I have at my disposal a register of words, expressions, syntactic constructions and last but not least para-linguistic means that correspond with this expressive function of language. Probably personal speaking has a set of distinctions that are character-ized in terms of different distances from individual speaking. When the relation between individual and personal speaking goes astray, the distancing from my individual 'I1 can turn into alienation from myself.

2019 ◽  
Vol 16 (2-3) ◽  
pp. 161-179
Author(s):  
Outi Paloposki

The article looks at book production and circulation from the point of view of translators, who, as purchasers and readers of foreign-language books, are an important mediating force in the selection of literature for translation. Taking the German publisher Tauchnitz's series ‘Collection of British Authors’ and its circulation in Finland in the nineteenth and early twentieth century as a case in point, the article argues that the increased availability of English-language books facilitated the acquiring and honing of translators' language skills and gradually diminished the need for indirect translating. Book history and translation studies meet here in an examination of the role of the Collection in Finnish translators' work.


2020 ◽  
Vol 7 (2) ◽  
pp. 34-41
Author(s):  
VLADIMIR NIKONOV ◽  
◽  
ANTON ZOBOV ◽  

The construction and selection of a suitable bijective function, that is, substitution, is now becoming an important applied task, particularly for building block encryption systems. Many articles have suggested using different approaches to determining the quality of substitution, but most of them are highly computationally complex. The solution of this problem will significantly expand the range of methods for constructing and analyzing scheme in information protection systems. The purpose of research is to find easily measurable characteristics of substitutions, allowing to evaluate their quality, and also measures of the proximity of a particular substitutions to a random one, or its distance from it. For this purpose, several characteristics were proposed in this work: difference and polynomial, and their mathematical expectation was found, as well as variance for the difference characteristic. This allows us to make a conclusion about its quality by comparing the result of calculating the characteristic for a particular substitution with the calculated mathematical expectation. From a computational point of view, the thesises of the article are of exceptional interest due to the simplicity of the algorithm for quantifying the quality of bijective function substitutions. By its nature, the operation of calculating the difference characteristic carries out a simple summation of integer terms in a fixed and small range. Such an operation, both in the modern and in the prospective element base, is embedded in the logic of a wide range of functional elements, especially when implementing computational actions in the optical range, or on other carriers related to the field of nanotechnology.


2004 ◽  
Vol 155 (5) ◽  
pp. 142-145 ◽  
Author(s):  
Claudio Defila

The record-breaking heatwave of 2003 also had an impact on the vegetation in Switzerland. To examine its influences seven phenological late spring and summer phases were evaluated together with six phases in the autumn from a selection of stations. 30% of the 122 chosen phenological time series in late spring and summer phases set a new record (earliest arrival). The proportion of very early arrivals is very high and the mean deviation from the norm is between 10 and 20 days. The situation was less extreme in autumn, where 20% of the 103 time series chosen set a new record. The majority of the phenological arrivals were found in the class «normal» but the class«very early» is still well represented. The mean precocity lies between five and twenty days. As far as the leaf shedding of the beech is concerned, there was even a slight delay of around six days. The evaluation serves to show that the heatwave of 2003 strongly influenced the phenological events of summer and spring.


2020 ◽  
Vol 16 (6) ◽  
pp. 784-795
Author(s):  
Krisnna M.A. Alves ◽  
Fábio José Bonfim Cardoso ◽  
Kathia M. Honorio ◽  
Fábio A. de Molfetta

Background:: Leishmaniosis is a neglected tropical disease and glyceraldehyde 3- phosphate dehydrogenase (GAPDH) is a key enzyme in the design of new drugs to fight this disease. Objective:: The present study aimed to evaluate potential inhibitors of GAPDH enzyme found in Leishmania mexicana (L. mexicana). Methods: A search for novel antileishmanial molecules was carried out based on similarities from the pharmacophoric point of view related to the binding site of the crystallographic enzyme using the ZINCPharmer server. The molecules selected in this screening were subjected to molecular docking and molecular dynamics simulations. Results:: Consensual analysis of the docking energy values was performed, resulting in the selection of ten compounds. These ligand-receptor complexes were visually inspected in order to analyze the main interactions and subjected to toxicophoric evaluation, culminating in the selection of three compounds, which were subsequently submitted to molecular dynamics simulations. The docking results showed that the selected compounds interacted with GAPDH from L. mexicana, especially by hydrogen bonds with Cys166, Arg249, His194, Thr167, and Thr226. From the results obtained from molecular dynamics, it was observed that one of the loop regions, corresponding to the residues 195-222, can be related to the fitting of the substrate at the binding site, assisting in the positioning and the molecular recognition via residues responsible for the catalytic activity. Conclusion:: he use of molecular modeling techniques enabled the identification of promising compounds as inhibitors of the GAPDH enzyme from L. mexicana, and the results obtained here can serve as a starting point to design new and more effective compounds than those currently available.


2019 ◽  
Vol 5 (2) ◽  
pp. 83-99
Author(s):  
Francisco Jesús Ferreiro Seoane ◽  
Manuel Octavio Del Campo Villares

Background: The objective of this article is to analyse if there are significant relationships between the most valuable companies operating in Spain regarding professional performance, according to nationality and location within their Autonomous Communities or any superior aggrupation. To do that, a sample of 100 companies has been selected. Methods: The methodology followed is based on the selection of the 100 highestvalued companies from the point of view of Human Resources’ policy for the period 2013-2016 and through the measurement of six factors: Talent Management, Retribution, Work environment, CSR, Training and Employees’ perception, and classified by nationality and location. The study was based on 12 hypotheses, using the Unifactorial Variance’s Analysis, Pearson correlations and regressions. One limitation could be the fact that this study refers to a particular period, focusing on Spain and the variables mentioned, based on questionnaires. The added value of this work lies on the newness as it has a quantitative character, and on the fact that most of the hypotheses do not comply. Results and Conclusion: This allows to deny certain beliefs that affirm that European and American companies operating in Spain are more attractive than the Spanish or the Mediterranean ones.


2021 ◽  
pp. 1354067X2110173
Author(s):  
Danilo Silva Guimarães

This article aims to discuss the relationship between personal cultural experience and knowledge construction in psychology, from the perspective of the Semiotic-Cultural Constructivism. The thoughts here presented are, at the same time, from within psychology and about psychology. The researcher is culturally situated and science is a field of production of cultural works that aims to create perspectives of knowledge about the world. Researchers can and must create some detachment from their field of study to be able to understand the course of their own knowledge constructions. This detachment is achieved through a historical–philosophical view on the theoretical–methodological propositions of their field of research. As a case study, we selected for analysis the field’s pioneer productions, from the years 1982 to 2004. The material showed that the rationality that characterizes scientific research is directed, in this field, to creating semiotic resources for further developing reflexivity in psychology, as a recursive and open-ended process. The theoretical–methodological work of the researcher concerns its own personal cultural experience and the tradition of the already constructed knowledge, selected to a dialogue about the ethical implications of human action. Therefore, advances in psychological knowledge construction cannot be addressed from an external, allegedly neutral point of view, focused on the efficacy of the instruments resulting from the said “scientific progress.”


Animals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 812
Author(s):  
Ellie Coleman ◽  
Rebecca Scollen ◽  
Beata Batorowicz ◽  
David Akenson

This paper examines a selection of 21st-century international examples of exhibited visual artworks involving live or deceased animals. It seeks to reveal the risks and benefits of unique encounters with animals through art and to consider the ethical implications of artwork deploying animals. Australian and international animal protection laws are not explicit when it comes to the sourcing of animals for art nor for the direct inclusion of animals in artworks. This lack leads to a variety of artistic practices, some considered ethical while others are viewed as controversial, bordering on animal cruelty. Artwork selection is determined by a focus on high-profile artists who intentionally use animals in their practice and whose reputation has been fostered by this intention. The study provides insight into how the intentional use of ethically sourced animals within art practice can be a method of addressing hierarchal human–animal imbalances. Further, this study identifies unethical practices that may be best avoided regardless of the pro-animal political statements the artists put forward. Recommendations of how to better determine what is an acceptable use of animals in art with a view to informing legal guidelines and artistic best practice are presented.


2020 ◽  
Vol 10 (1) ◽  
pp. 454-461
Author(s):  
Piotr Sęk

AbstractLaser surface texturing is currently the most developed technique for producing fully reproducible microcavities on the surfaces of machine elements. From the point of view of texture technology, an important aspect is the proper selection of process parameters to obtain texture elements with desirable and repetitive geometries and physicochemical properties. Surface texturing improves mottling and fretting resistance and is also used wherever the adhesion properties of surface layers (printing techniques, bonding materials, biological and chemical activity, coatings, etc.) are important. The article shows the possibility of applying statistical functions to the selection of appropriate machining parameters to obtain microgeometry useful in the application of textured surfaces [1].


2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
P. Molavi ◽  
M. Karimollahi ◽  
M. Faridi

Background:Depression as a common psychiatric disorder can occur in two types: Endogenous or genetic and exogenous or Reactional. These two types of depression, from the point of view of response speed to treatment and type of appropriate drug for treatment are different. This study has been executed to compare therapeutic effects of different classes of anti-depressant drugs in treatment of genetic and Reactional depression.Materials and methods:Present survey is a clinical-trial study, a completely randomly block type, that has performed on 30 patients (male and female). Selection of study sample accomplished randomly among unipolar depressed patients that has referred to Ardabil’s psychiatry clinic diagnosed based on DSM-IV criteria. Researcher - Made questionnaire, Beck, and Catelle depression test were used to collect data. To analyze data, for completely randomly blocked designs, two-factor variance analysis method and F test were used.Results:This study showed that Genetical depression does not response treatment Rapidly and its response type is not good and persistent. From the point of view of time, Reactional depression has a delaying response but its response type is good and persistent. In addition, no difference was observed in efficacy of different classes of drugs for treatment of these two types of depression. The results of this research showed that there is no difference between treatment response of two types of depression (Genetical and Reactional).Conclusions:There is no preference in efficacy of different classes of drugs in treatment of these two types of depression.


2008 ◽  
Vol 2 (1) ◽  
pp. 249-273 ◽  
Author(s):  
Katja Ploog

AbstractChange is an ongoing process constitutive of human language to which will be refered by the term of dynamics. It will be worked out how mere interaction conditions the language dynamics and how the disposable structural resources will be coordinated in microsystems. Since from this point of view grammar exists as a process, it will be of interest to work out by what type of mechanisms a bilingual speaker elaborates his/her discourse. It will be discussed what can be called a (more) 'useful' construction and through what type of mechanisms the constructions get coordinated. We will argue that all discursive mechanisms are bound to satisfy the pragmatic demands of an actual speech production and that the most useful items are those which best satisfy these pragmatic demands.One of the most characteristic phenomena of the linguistic dynamics in Ivory Coast is the microsystem of LA: In a highly heterogeneous context of social interaction, LA is used in (the locally dominant) discursive traditions of French and Mande languages, undergoing a grammaticalization process separately in each of them and used - consequently - in various constructions. The wide range of its referential values, the very importance of the negotiation of discourse referents between speaker and hearer and its simple phonological form seem to predestine LA to get reappropriated and to become a 'favorite' form in the emergent speech community.


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