Ultra-Processed Foods Consumption and Lipid Profile in Brazilian Children

Abstract Objectives The consumption of ultra-processed foods (UPF) plays a role in the development of chronic diseases, but there is a limited number of studies targeting the association of its intake and risk of diseases in childhood. Our objective was to determine longitudinal trends of UPF intake and their impact on blood lipids in young children. Methods A longitudinal cohort study of children at 3 and 6 years of age from low-income families in southern Brazil was conducted. Dietary data were collected through two 24-h recalls and UPF consumption was assessed by NOVA, a classification of foods based on the degree and purpose of industrial food processing. At 6 years of age, blood tests were performed to measure total cholesterol, LDL-cholesterol, HDL-cholesterol, and triglycerides. Multivariable linear regression analyses were used to assess differences across tertiles of UPF consumption at age 3 years on lipid profile at age 6 years. Results Complete data were available for 308 children; of which, 52.0% were male. Regarding nutritional status, 18.0% of children at age 3 years and 18.4% at age 6 years were overweight. UPF represented a mean of 43% and 47% of the total energy intake at 3 and 6 years of age, respectively. The overall dietary contribution of UPF increased by 10% across three years of assessment. Higher UPF intake at age 3 years was associated with increased levels of total cholesterol (tertile 3 vs. tertile 1; β 8.51 mg/dL [95% CI 1.65 to 15.37]) and triglycerides (tertile 3 vs. tertile 1; β 9.69 mg/dL [(95% CI 0.97 to 18.42]) later at age 6 years. Conclusions An increase in UPF consumption was associated with poor lipid profile at age 6 years. The results of our study emphasize the need for innovative strategies to reduce the consumption of ultra-processed foods, especially in early ages, to ensure lifelong health. Funding Sources Brazilian Ministry of Health, Research Support Foundation of the State of Rio Grande do Sul (FAPERGS), Brazilian National Council for Scientific and Technological Development (CNPq) and Coordination for the Improvement of Higher Education Personnel (CAPES).

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A Comparative Study of Lipid Profile in Obese and Nonobese Men attending Master Health Checkup

Indian Journal of Medical Biochemistry ◽

10.5005/jp-journals-10054-0024 ◽

2017 ◽

Vol 21 (2) ◽

pp. 73-75

Author(s):

S Vinod Babu ◽

Anusha R Jagadeesan ◽

Jothimalar Ramalingam

Keyword(s):

Comparative Study ◽

Lipid Profile ◽

Total Cholesterol ◽

Ldl Cholesterol ◽

Density Lipoprotein ◽

Hdl Cholesterol ◽

P Value ◽

Health Checkup ◽

Group I ◽

Significant Difference

ABSTRACT Introduction Obesity is emerging as an epidemic worldwide. Obesity is associated with a number of comorbid conditions, such as diabetes mellitus, hypertension, cancer, dyslipidemia, cardiovascular abnormalities, anemia, obstructive sleep apnea, and psychosocial abnormalities. Aim This study aims at comparing the lipid profile levels of obese and nonobese men. Materials and methods This was a case—control study conducted at a tertiary care center. Totally, 80 men in the age group of 20 to 47 years attending the master health checkup were included in the study, out of which 40 men with normal body mass index (BMI) of 18 to 25 belonged to group I and 40 men with increased BMI of 30 and above belonged to group II. Lipid profile parameters, such as triglycerides (TGLs), total cholesterol, high-density lipoprotein (HDL) cholesterol, and low-density lipoprotein (LDL) cholesterol were estimated in them. The data were statistically analyzed using Statistical Package for the Social Sciences (SPSS) software version 15.0. Results Statistically significant difference was found in the total cholesterol levels with a p-value of 0.040 while the difference in LDL cholesterol was statistically highly significant with a p-value of 0.040. Conclusion Among lipid profile parameters, only total cholesterol and LDL cholesterol showed significant difference between the obese and nonobese individuals. However, the other parameters like HDL cholesterol and TGLs did not show any significant difference. How to cite this article Babu SV, Jagadeesan AR, Ramalingam J. A Comparative Study of Lipid Profile in Obese and Nonobese Men attending Master Health Checkup. Indian J Med Biochem 2017;21(2):73-75.

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Effects of Red Pitaya (Hylocereus polyrhizus) on Lipid Profile of Male White Rats (Rattus norvegicus) Receiving High Fat Diet

Folia Medica Indonesiana ◽

10.20473/fmi.v54i1.8046 ◽

2018 ◽

Vol 54 (1) ◽

pp. 16 ◽

Cited By ~ 1

Author(s):

Wiwik Werdiningsih ◽

Suhartati Suhartati

Keyword(s):

Lipid Profile ◽

Total Cholesterol ◽

Ldl Cholesterol ◽

Hdl Cholesterol ◽

Fruit Peel ◽

Cholesterol Levels ◽

White Rats ◽

Wistar Strain ◽

Dragon Fruit ◽

Pap Method

Red dragon fruit (Hylocereus polyrhizus) peel contains anthocyanin, fiber and vitamin C, so it can be used to improve lipid profile in dyslipidemia. The peel of the dragon fruit is not durable, so in this study we used freeze-dried dragon fruit peel. The aim of this study was to prove that the administration of the red dragon fruit peel in a dose of 0.72 g/200 g BW, 1.08 g/200 g BW, and 1.44 g/200 g BW of rat per day for 28 days may improve lipid profile in male wistar strain white rats with high-fat diet. Lipid profiles were studied by examining of total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides. This was a pure experimental study using randomized post test only control group design. This study used experimental animal of 30 male wistar strain white rats which were divided into five groups. Measurements of total, LDL, and HDL cholesterol levels were done by CHOD-PAP method, while triglyceride level was measured with GPO-PAP method. Data were analyzed statistically by One Way Anova test. The results of this study indicated that giving the peel of red dragon fruit as much as 0.72 g lowered total cholesterol levels, 1.08 g lowered total and LDL cholesterol levels, and 1.44 g lowered total cholesterol, LDL cholesterol, triglyceride levels, and raised HDL cholesterol level. Red dragon fruit peel can be used alternatively to improve lipid profile in dyslipidemia.

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HEALTH CARE FOR JUVENILE DELINQUENTS

PEDIATRICS ◽

10.1542/peds.52.3.434 ◽

1973 ◽

Vol 52 (3) ◽

pp. 434-435

Author(s):

Victor Eisner ◽

Robert I. Sholtz

Keyword(s):

Health Care ◽

Juvenile Delinquency ◽

Young People ◽

Low Income ◽

Juvenile Delinquents ◽

Juvenile Court ◽

National Council ◽

Health Supervision ◽

Low Income Families ◽

Detention Facilities

Pediatricians have long interested themselves in the health of juvenile delinquents. The Academy first appointed a Committee on Juvenile Delinquency in 1955. Although this Committee has changed its title to the Committee on Youth and has expanded its role to include other problems and concerns of young people, it still concerns itself with the health supervision of youth in detention facilities. It has now developed, with the endorsement of the National Council of Juvenile Court Judges, written standards for health care provided in juvenile court institutions.1 Juvenile delinquents come largely from low income families, and often from families with serious social problems.

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Abstract P128: Serum Lipid Levels at Adolescence can Predict Adult Dyslipidemia in South Korea - The Kangwha Study

Circulation ◽

10.1161/circ.135.suppl_1.p128 ◽

2017 ◽

Vol 135 (suppl_1) ◽

Author(s):

Jung H Lee ◽

Hyeon C Kim ◽

Dae R Kang ◽

Il Suh

Keyword(s):

Blood Pressure ◽

Body Mass Index ◽

Logistic Regression ◽

South Korea ◽

Lipid Profile ◽

Total Cholesterol ◽

Serum Lipid ◽

Hdl Cholesterol ◽

Multiple Logistic Regression ◽

Auc Value

Introduction: Several studies have examined tracking pattern of lipid profile level during long follow-up periods in Western countries. However, there have been few such studies in East Asia. Hypothesis: We assessed the hypothesis that there exists tracking pattern of lipid profile level from adolescence to adulthood, and lipid measurements in adolescence can predict adult dyslipidemia in South Korea. Methods: The Kangwha Study was a community-based prospective cohort study that started in 1986 in Kangwha County, South Korea . A total of 400 participants (54% women) whose serum total cholesterol, triglyceride, and high density lipoprotein (HDL) cholesterol level were measured at least once during adolescence (1992-1996), and repeatedly measured at least once during adulthood (2005-2015) were enrolled in our study. Body mass index, waist circumstance, and blood pressure were measured at all measurements. Family history of cardiovascular disease, smoking history, and presence of adult dyslipidemia were checked at adulthood. The tracking pattern of lipid profile level was determined by tracking coefficients (low: <0.30; moderate: 0.30-0.59; moderately high: 0.60-0.89; high: ≥0.90). The tracking coefficients were calculated by Generalized Estimating Equation. The predictability of adult dyslipidemia was assessed by multiple logistic regression and area under curve (AUC) value. Additional analyses were performed to find out whether repeated lipid measurements during adolescence can enhance the predictability of adult dyslipidemia or not. Results: The presence of adult dyslipidemia was 26.3% (105 of 400). Mean age of study participants at enrollment is 13.8 years (SD, 1.6 years), and that at adulthood is 30.1 years (SD, 3.7 years). When adjusted for age, body mass index, waist circumstance, and blood pressure, the tracking coefficient of total cholesterol was 0.59 (95% confidence interval (CI), 0.54-0.63), that of triglyceride was 0.39 (95% CI, 0.28-0.49), and that of HDL cholesterol was 0.51 (95% CI, 0.46-0.55). The AUC value of our multiple logistic regression model on adult dyslipidemia without lipid profile levels at adolescence was 0.77 (95% CI, 0.72-0.83), and that with lipid profile levels at adolescence was 0.80 (95% CI, 0.75-0.85). P value for AUC comparison was significant (p=0.02). In additional analyses, using the average lipid profile levels in multiple lipid measurements at adolescence did not significantly improve the AUC value (p>0.09). Conclusion: In conclusion, moderate tracking patterns of serum lipid profile level were shown in this study. Serum lipid profile measurements at adolescence could help the prediction of adult dyslipidemia. The results of this study supported the need of lipid profile screening at adolescence.

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Identification and validation of seven new loci showing differential DNA methylation related to serum lipid profile: an epigenome-wide approach. The REGICOR study

Human Molecular Genetics ◽

10.1093/hmg/ddw285 ◽

2016 ◽

Vol 25 (20) ◽

pp. 4556-4565 ◽

Cited By ~ 47

Author(s):

S Sayols-Baixeras ◽

I Subirana ◽

C Lluis-Ganella ◽

F Civeira ◽

J Roquer ◽

...

Keyword(s):

Risk Factors ◽

Dna Methylation ◽

Lipid Profile ◽

Total Cholesterol ◽

Intergenic Region ◽

Serum Lipid ◽

Hdl Cholesterol ◽

Differential Methylation ◽

P Value ◽

Epigenetic Mark

Abstract Lipid traits (total, low-density and high-density lipoprotein cholesterol, and triglycerides) are risk factors for cardiovascular disease. DNA methylation is not only an inherited but also modifiable epigenetic mark that has been related to cardiovascular risk factors. Our aim was to identify loci showing differential DNA methylation related to serum lipid levels. Blood DNA methylation was assessed using the Illumina Human Methylation 450 BeadChip. A two-stage epigenome-wide association study was performed, with a discovery sample in the REGICOR study (n = 645) and validation in the Framingham Offspring Study (n = 2,542). Fourteen CpG sites located in nine genes (SREBF1, SREBF2, PHOSPHO1, SYNGAP1, ABCG1, CPT1A, MYLIP, TXNIP and SLC7A11) and 2 intergenic regions showed differential methylation in association with lipid traits. Six of these genes and 1 intergenic region were new discoveries showing differential methylation related to total cholesterol (SREBF2), HDL-cholesterol (PHOSPHO1, SYNGAP1 and an intergenic region in chromosome 2) and triglycerides (MYLIP, TXNIP and SLC7A11). These CpGs explained 0.7%, 9.5% and 18.9% of the variability of total cholesterol, HDL cholesterol and triglycerides in the Framingham Offspring Study, respectively. The expression of the genes SREBF2 and SREBF1 was inversely associated with methylation of their corresponding CpGs (P-value = 0.0042 and 0.0045, respectively) in participants of the GOLDN study (n = 98). In turn, SREBF1 expression was directly associated with HDL cholesterol (P-value = 0.0429). Genetic variants in SREBF1, PHOSPHO1, ABCG1 and CPT1A were also associated with lipid profile. Further research is warranted to functionally validate these new loci and assess the causality of new and established associations between these differentially methylated loci and lipid metabolism.

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Lipid Profile and Clinical Characteristics of Women with Gestational Diabetes Mellitus and Preeclampsia

Journal of Medical Biochemistry ◽

10.2478/v10011-009-0007-x ◽

2009 ◽

Vol 28 (2) ◽

pp. 72-81 ◽

Cited By ~ 4

Author(s):

Donovan McGrowder ◽

Kevin Grant ◽

Rachael Irving ◽

Lorenzo Gordon ◽

Tazhmoye Crawford ◽

...

Keyword(s):

Diabetes Mellitus ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Lipid Profile ◽

Total Cholesterol ◽

Clinical Characteristics ◽

Hdl Cholesterol ◽

Normal Glucose Tolerance ◽

Increased Risk ◽

Normal Glucose

Lipid Profile and Clinical Characteristics of Women with Gestational Diabetes Mellitus and Preeclampsia Gestational diabetes mellitus (GDM) is associated with increased risk of pregnancy-induced hypertension and other maternal and foetal complications of pregnancy. The aims of the study were to evaluate the serum lipid profile of women with GDM, and determine the number of women with GDM who have preeclampsia (PE). A retrospective study of 84 women with GDM and 90 pregnant women with normal glucose tolerance (controls) was conducted. Women with GDM had significantly higher parity (p=0.047), total cholesterol (p=0.039) and triglycerides (p=0.033), but non-significantly lower HDL-cholesterol (p=0.086) when compared to controls. Systolic blood pressure was significantly elevated in women with GDM coupled with PE (GDM-PE; p=0.015), the mean birth weight of infants born to women with GDM-PE was significantly lower than that of women with only GDM (p=0.025). Women with GDM-PE had significantly higher triglycerides (p=0.020), had to be more multi-gravida (p=0.047) with significantly elevated VLDL-cholesterol (p=0.037) when compared with women with only GDM. 11.9% of women with GDM had PE. On the basis of these findings, it can be concluded that GDM is associated with hyperlipidaemia as evident by the significantly elevated total cholesterol and triglyceride concentrations. Women with dyslipidaemia and GDM are at risk of developing preeclampsia. It is imperative that blood lipids be evaluated in women with GDM during antenatal care as it would be helpful in the early detection and treatment of PE.

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A Pragmatic Internet Intervention to Promote Positive Parenting and School Readiness in Early Childhood: Initial Evidence of Program Use and Satisfaction (Preprint)

10.2196/preprints.14518 ◽

2019 ◽

Author(s):

Lucy McGoron ◽

Hilary Horn Ratner ◽

Kathryn AG Knoff ◽

Erica Hvizdos ◽

Steven J Ondersma

Keyword(s):

School Readiness ◽

Low Income ◽

Text Messages ◽

Parenting Programs ◽

Program Text ◽

Childcare Centers ◽

Web Based ◽

Innovative Strategies ◽

Low Income Families ◽

Website Use

BACKGROUND Internet-based parenting programs have the potential to connect families to research-informed materials to promote positive child development. However, such programs can only succeed to the extent that the intended population engages with them. OBJECTIVE This study aimed to evaluate engagement in the 5-a-Day Parenting program, a technology-based program designed with low-income families in mind, to promote daily use of 5 specific parenting activities conducive to children’s school readiness. Following earlier pilot data, the program was enhanced with an initial motivational e-intervention and tailored text messages designed to promote engagement. METHODS Parents were recruited from local childcare centers and through a participant registry. We examined rates of receipt of program text messages and use of video-based content on the program website, 3 factors that may affect website use, and satisfaction with key program elements. RESULTS A total of 360 parents of young children learned about the study and had the opportunity to use the 5-a-Day Parenting website. Of these, 94 parents participated in the study, and 33% (31/94) accessed the video-based content on the website at least once. No association was found between website use and program recruitment approach, program-affiliation message, sociocontextual risk, and baseline use of the five parenting activities. Satisfaction with text messages and video-based content was high. CONCLUSIONS For some parents, technology-based programs appear useful; however, engagement could still be enhanced. Additional research should seek innovative strategies for promoting engagement in Web-based parenting programs.

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Pengaruh propolis terhadap profil lipid plasma tikus model hiperkolesterolemia

Jurnal Gizi Klinik Indonesia ◽

10.22146/ijcn.17600 ◽

2012 ◽

Vol 8 (3) ◽

pp. 106

Author(s):

Krisnansari Diah ◽

Ariadne Tiara Hapsari ◽

Evy Sulistyoningrum ◽

Agus Prastowo

Keyword(s):

Lipid Profile ◽

Total Cholesterol ◽

Ldl Cholesterol ◽

Plasma Cholesterol ◽

Hdl Cholesterol ◽

Sprague Dawley ◽

High Cholesterol ◽

Cholesterol Levels ◽

Group I ◽

Before And After

Background: Nowadays, cardiovascular disease caused by hypercholesterolemia has become the main cause of death. Propolis has been used widely to reduce plasma cholesterol levels.Objective: The aims of this research was to study the effect of propolis on lipid profile of hypercholesterolemic Sprague Dawley rats.Method: This was an experimental study with pre-post test. Twenty four (24) male Sprague Dawley rats aged 12-16 week old, weighing 125-200 g were allocated into 4 groups. Group I received standard meal + aquadest-gavage; group II received high cholesterol meal + PTU 0,01 + aquadest gavage; group III received high cholesterol meal + PTU 0,01 + 0,027 g propolis gavage; group IV received high cholesterol meal + PTU 0,01 + 0,054 g propolis gavage. Total cholesterol, triglycerides, HDL cholesterol and LDL cholesterol levels before and after treatment were measured. The data were then analyzed with One Way Anova.Results: The study showed that there were no significant differences in changes of body weight. There were significant differences in total cholesterol levels between all groups of treatment. Triglyceride levels were significantly different among all groups, except between group I and IV. Furthermore, the HDL cholesterol levels of group I vs III and group I vs IV were significantly different. However, there were no differences found in LDL cholesterol levels among all groups of treatment.Conclusion: Provision of 0,027 g and 0,054 g propolis improve lipid profile (total cholesterol, triglyceride and HDL cholesterol levels) of hypercholesterolemic rats.

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Pharmacognosy and Therapeutics: Interaction

10.47363/jprsr/2021(2)109 ◽

2021 ◽

pp. 1-4

Author(s):

Shah Murad Mastoi Baloch ◽

◽

Nusratullah Khan ◽

Keyword(s):

Lipid Profile ◽

Total Cholesterol ◽

Ldl Cholesterol ◽

Curcuma Longa ◽

Research Work ◽

Hdl Cholesterol ◽

The Body ◽

Base Line ◽

Group I ◽

Fenugreek Leaves

In the body, liver produces approximately 80% of the cholesterol whereas rest of the cholesterol is obtained from the food like fish, eggs, meat, etc. After having a meal, cholesterol is digested and absorbed in small intestine then the metabolism and storage occurred in the liver. The cholesterol may be secreted by the liver whenever the requirement of cholesterol is needed by the body. Cholesterol is not present in the food which is derived from the plants. We in this study have compared hypolipidemic effects of Fenugreek, Curcuma longa, and Lemon. Study was conducted at Jinnah Hospital Lahore-Pakistan from January 2018 to May 2018. Ninety hyperlipidemic patients of age group 19 to 70 were included in the study. Exclusion criteria were diabetic, alcoholic additives, hypertensive patients and those whose kidney or liver functions were impaired. Consent was taken from all participants. Their base line lipid profile was taken in biochemistry laboratory of the hospital. They were divided in three groups i.e. 30 patients in each group. Group-I was advised to take 500 mg of Curcuma longa (haldi) mixed in fresh milk without cream, thrice daily for two months. Group-II patients were advised to take 100 grams of Fenugreek leaves mixed with salad in each meal (thrice daily) for the period of two months. Group-III patients were advised to take 40 ml of fresh lemon juice mixed with 40 ml mineral water thrice daily for two months. They all were advised not to take heavy meal rich with any type of fat like junk food etc. One hour daily brisk walk was advised to all participants. 15 days follow up visit was scheduled for them. After two months their lipid profile was redetermined. When results were compiled and statistically analyzed by applying paired ‘t’ test, it revealed that Curcuma longa decreased total cholesterol, TG, LDL cholesterol 16.10, 20.01, and 17.59 mg/dl respectively. Fenugreek decreased total cholesterol, TGs, and LDL cholesterol 14.70, 17.33, and 17.06 mg/dl respectively. Lemon in two months therapy decreased total cholesterol, TGs, and LDL cholesterol 15.45, 10.13, and 11.97 mg/dl respectively. None of the above mentioned herbs raised HDL cholesterol significantly. It was concluded from this research work that Curcuma longa, Fenugreek leaves and Lemon are mild to moderately effective hypolipidemic herbs to lower total plasma cholesterol, triglycerides, and LDL cholesterol but have no potential to raise HDL cholesterol when analyzed biostatistically.

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PERBANDINGAN PROFIL LIPID PADA SERUM DARAH PENDERITA HIPERTENSI DAN NORMOTENSI

Jurnal BIOMA ◽

10.21009/bioma11(2).3 ◽

2015 ◽

Vol 11 (2) ◽

pp. 131

Author(s):

Pratiwi Widyamurti ◽

Rusdi Rusdi ◽

Sri Rahayu

Keyword(s):

Blood Serum ◽

Lipid Profile ◽

Total Cholesterol ◽

Ldl Cholesterol ◽

Clinical Chemistry ◽

Hdl Cholesterol ◽

Mean Value ◽

Cross Sectional ◽

Ex Post ◽

The Mean

ABSTRACT Increased blood pressure more than 140/90 mmHg taken from three measurement in 24 hours can be diagnosed as hypertension. Abnormality of lipid values condition was found at many hypertensive. Based on this reason examination of lipid profile in hypertensive and normotensive should be done. The aim of this research was to measure and compare lipid profile on blood serum in hypertensive and normotensive. Lipid profile was measured by Konelab 20XT clinical chemistry analyzer. Ex Post Facto used as method and Cross-sectional used as design. A total of 50 blood samples collected from Hypertensive (N1=25) and normotensive (N2=25) from June to August 2014. SPSS 16.0 was used to analyze the data, T-test was used to compare value of LDL cholesterol, HDL cholesterol and total cholesterol while U Mann-Whitney test was used to compare value of triglyceride. The result of this research showed that the mean value of triglyceride was 146.56 mg/dL in hypertensive and 143.92 mg/dL in normotensive (p=0.11). The mean value of LDL cholesterol was 129.80 mg/dL in hypertensive and 136.72 mg/dL in normotensive (p=0.62). The mean value of HDL cholesterol was 38.80 mg/dL in hypertensive and 45.04 mg/dL in normotensive (p=0.1). The mean value of total cholesterol was 201.04 mg/dL in hypertensive and 221.88 mg/dL in normotensive (p=0.25). In conclusion, there was no different of lipid profile on blood serum in hypertensive and normotensive. Keywords: hypertension, lipid profile, normotensive

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