scholarly journals Regulatory responses to medical machine learning

Author(s):  
Timo Minssen ◽  
Sara Gerke ◽  
Mateo Aboy ◽  
Nicholson Price ◽  
Glenn Cohen

Abstract Companies and healthcare providers are developing and implementing new applications of medical artificial intelligence, including the artificial intelligence sub-type of medical machine learning (MML). MML is based on the application of machine learning (ML) algorithms to automatically identify patterns and act on medical data to guide clinical decisions. MML poses challenges and raises important questions, including (1) How will regulators evaluate MML-based medical devices to ensure their safety and effectiveness? and (2) What additional MML considerations should be taken into account in the international context? To address these questions, we analyze the current regulatory approaches to MML in the USA and Europe. We then examine international perspectives and broader implications, discussing considerations such as data privacy, exportation, explanation, training set bias, contextual bias, and trade secrecy.

2021 ◽  
Vol 11 (1) ◽  
pp. 32
Author(s):  
Oliwia Koteluk ◽  
Adrian Wartecki ◽  
Sylwia Mazurek ◽  
Iga Kołodziejczak ◽  
Andrzej Mackiewicz

With an increased number of medical data generated every day, there is a strong need for reliable, automated evaluation tools. With high hopes and expectations, machine learning has the potential to revolutionize many fields of medicine, helping to make faster and more correct decisions and improving current standards of treatment. Today, machines can analyze, learn, communicate, and understand processed data and are used in health care increasingly. This review explains different models and the general process of machine learning and training the algorithms. Furthermore, it summarizes the most useful machine learning applications and tools in different branches of medicine and health care (radiology, pathology, pharmacology, infectious diseases, personalized decision making, and many others). The review also addresses the futuristic prospects and threats of applying artificial intelligence as an advanced, automated medicine tool.


2017 ◽  
Vol 5 (1) ◽  
pp. 54-58 ◽  
Author(s):  
Zhi-Hua Zhou

Abstract Machine learning is the driving force of the hot artificial intelligence (AI) wave. In an interview with NSR, Prof. Thomas Dietterich, the distinguished professor emeritus of computer science at Oregon State University in the USA, the former president of Association of Advancement of Artificial Intelligence (AAAI, the most prestigious association in the field of artificial intelligence) and the founding president of the International Machine Learning Society, talked about exciting recent advances and technical challenges of machine learning, as well as its big impact on the world.


2020 ◽  
Vol 73 ◽  
pp. 01025
Author(s):  
Zuzana Rowland ◽  
Jaromír Vrbka ◽  
Marek Vochozka

The USA decided to regulate the trade more by imposing tariffs on specific types of traded goods. It is therefore more interesting to find out whether the current technologies based on artificial intelligence with time series influenced by extraordinary factors such as the trade war between two powers are able to work. The objective of the contribution is to examine and subsequently equalize two time series – the USA import from the PRC and the USA export to the PRC. The dataset shows the course of the time series at monthly intervals between January 2000 and July 2019. 10,000 multilayer perceptron networks (MLP) are generated, out of which 5 with the best characteristics are retained. It has been proved that multilayer perceptron networks are a suitable tool for forecasting the development of the time series if there are no sudden fluctuations. Mutual sanctions of both states did not affect the result of machine learning forecasting.


2022 ◽  
pp. 162-175
Author(s):  
S. Meenakshi Sundaram ◽  
Tejaswini R. Murgod

This chapter provides an insight into building healthcare applications that are deployed in the cloud storage using edge computing and IoT data analytics approaches. Data is collected from environments both within or external to the hospital. The devices that are connected enable the healthcare providers to monitor patients at large distances, manage chronic disease, and manage medication dosages. The data from these devices can be added to clinical research to gain an insight into the participant's experiences. Artificial intelligence techniques like machine learning or deep learning can be employed at the edge of the networks for IoT analytics of multiple data streams in online mode. The industrial edge computing is growing rapidly from 7% in 2019 to being expected to reach approximately 16% by 2025. The total market for intelligent industrial edge computing that includes hardware, software, services has reached $11.6B in 2019 and is expected to increase to $30.8B by 2025.


2022 ◽  
Vol 14 (2) ◽  
pp. 1-15
Author(s):  
Lara Mauri ◽  
Ernesto Damiani

Large-scale adoption of Artificial Intelligence and Machine Learning (AI-ML) models fed by heterogeneous, possibly untrustworthy data sources has spurred interest in estimating degradation of such models due to spurious, adversarial, or low-quality data assets. We propose a quantitative estimate of the severity of classifiers’ training set degradation: an index expressing the deformation of the convex hulls of the classes computed on a held-out dataset generated via an unsupervised technique. We show that our index is computationally light, can be calculated incrementally and complements well existing ML data assets’ quality measures. As an experimentation, we present the computation of our index on a benchmark convolutional image classifier.


Today is the generation of Machine Learning and Artificial Intelligence. Machine Learning is a field of scientific study and statistical models to predict the answers of never before asked questions. Machine Learning algorithms use a huge quantity of sample data that is further used to generate model. The higher amount and quality of training set lead to higher accuracy in approximate result calculation. ML is the most popular field to research and also helpful in pattern finding, artificial intelligence and data analysis. In this paper we are going to explain the basic concept of Machine Learning with its various types of methods. These methods can be used according to user’s requirement. Machine Learning tasks are divided into various categories . These tasks are accomplished by computer system without being explicitly programmed.


2021 ◽  
Vol 7 (1) ◽  
pp. 39
Author(s):  
José Bobes-Bascarán ◽  
Eduardo Mosqueira-Rey ◽  
David Alonso-Ríos

At present, the great majority of Artificial Intelligence (AI) systems require the participation of humans in their development, tuning, and maintenance. Particularly, Machine Learning (ML) systems could greatly benefit from their expertise or knowledge. Thus, there is an increasing interest around how humans interact with those systems to obtain the best performance for both the AI system and the humans involved. Several approaches have been studied and proposed in the literature that can be gathered under the umbrella term of Human-in-the-Loop Machine Learning. The application of those techniques to the health informatics environment could provide a great value on prognosis and diagnosis tasks contributing to develop a better health service for Cancer related diseases.


2017 ◽  
Vol 15 (4) ◽  
pp. 54
Author(s):  
András Lőrincz

Cikkemben érveket hozok fel amellett, hogy, hogy a technológiai fejlődés ma nagy lehetőségeket kínálnak az egészségügy és a jólét számára. Nézetem szerint (1) az „okos” eszközök (smart tools) és a különböző viselhető érzékelők, (2) az adatgyűjtés és az adatbányászati módszerek, (3) a három dimenziós (3D-s) képi rögzítési és képi feldolgozási eszközök, (4) a 3D-s, bonyolult fizikai motorral rendelkező, például grafikai modellek, valamint (5) a crowdsourcing-on (outsourcing: külső erőforrások igénybevétele, crowdsourcing: külső emberi erőforrások tömeges igénybevétele) alapuló emberalapú számítások (human-based computing), terén történő nagy és sikeres erőfeszítések hatalmas változásokat indítanak el. Nem állítom, bár tagadni sem tudom azt, hogy a mesterséges intelligencia eszközei néhány év múlva elérik az emberi intelligencia szintjét, mert ez lehetséges. Véleményem szerint, az egészségügy és a jólét területén gyors fejlődés lehetséges az egészségügyi és jóléti szakértők, és a motivált mérnökök közötti aktív együttműködés útján. --- Artificial Intelligence, Health and Wellbeing: prospects for machine learning, crowdsourcing and self-annotation We argue that recent technology developments – e.g. smart tools and wearable sensors of diverse kinds, data collection and data mining methods, 3D visual recording and visual processing methods, 3D models of the environment with robust physics engine – and new applications of human computing and crowdsourcing hold great promises for health and wellbeing. We are neither claiming nor excluding that human intelligence will be reached in some years from now, but make the above claim, which is both weaker and stronger. We believe that fast developments for health and wellbeing are the question of active collaboration between health and wellbeing experts and motivated engineers.


Biomolecules ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 793
Author(s):  
Julia Moran-Sanchez ◽  
Antonio Santisteban-Espejo ◽  
Miguel Angel Martin-Piedra ◽  
Jose Perez-Requena ◽  
Marcial Garcia-Rojo

Genomic analysis and digitalization of medical records have led to a big data scenario within hematopathology. Artificial intelligence and machine learning tools are increasingly used to integrate clinical, histopathological, and genomic data in lymphoid neoplasms. In this study, we identified global trends, cognitive, and social framework of this field from 1990 to 2020. Metadata were obtained from the Clarivate Analytics Web of Science database in January 2021. A total of 525 documents were assessed by document type, research areas, source titles, organizations, and countries. SciMAT and VOSviewer package were used to perform scientific mapping analysis. Geographical distribution showed the USA and People’s Republic of China as the most productive countries, reporting up to 190 (36.19%) of all documents. A third-degree polynomic equation predicts that future global production in this area will be three-fold the current number, near 2031. Thematically, current research is focused on the integration of digital image analysis and genomic sequencing in Non-Hodgkin lymphomas, prediction of chemotherapy response and validation of new prognostic models. These findings can serve pathology departments to depict future clinical and research avenues, but also, public institutions and administrations to promote synergies and optimize funding allocation.


10.28945/4838 ◽  
2021 ◽  
Vol 16 ◽  
pp. 331-369
Author(s):  
Anshul Jain ◽  
Tanya Singh ◽  
Satyendra Kumar Sharma

Aim/Purpose: The primary purpose of this study is to provide a cost-effective and artificial intelligence enabled security solution for IoT enabled healthcare ecosystem. It helps to implement, improve, and add new attributes to healthcare services. The paper aims to develop a method based on an artificial neural network technique to predict suspicious devices based on bandwidth usage. Background: COVID has made it mandatory to make medical services available online to every remote place. However, services in the healthcare ecosystem require fast, uninterrupted facilities while securing the data flowing through them. The solution in this paper addresses both the security and uninterrupted services issue. This paper proposes a neural network based solution to detect and disable suspicious devices without interrupting critical and life-saving services. Methodology: This paper is an advancement on our previous research, where we performed manual knowledge-based intrusion detection. In this research, all the experiments were executed in the healthcare domain. The mobility pattern of the devices was divided into six parts, and each one is assigned a dedicated slice. The security module regularly monitored all the clients connected to slices, and machine learning was used to detect and disable the problematic or suspicious devices. We have used MATLAB’s neural network to train the dataset and automatically detect and disable suspicious devices. The different network architectures and different training algorithms (Levenberg–Marquardt and Bayesian Framework) in MATLAB software have attempted to achieve more precise values with different properties. Five iterations of training were executed and compared to get the best result of R=99971. We configured the application to handle the four most applicable use cases. We also performed an experimental application simulation for the assessment and validation of predictions. Contribution: This paper provides a security solution for the IoT enabled healthcare system. The architectures discussed suggest an end-to-end solution on the sliced network. Efficient use of artificial neural networks detects and block suspicious devices. Moreover, the solution can be modified, configured and deployed in many other ecosystems like home automation. Findings: This simulation is a subset of the more extensive simulation previously performed on the sliced network to enhance its security. This paper trained the data using a neural network to make the application intelligent and robust. This enhancement helps detect suspicious devices and isolate them before any harm is caused on the network. The solution works both for an intrusion detection and prevention system by detecting and blocking them from using network resources. The result concludes that using multiple hidden layers and a non-linear transfer function, logsig improved the learning and results. Recommendations for Practitioners: Everything from offices, schools, colleges, and e-consultation is currently happening remotely. It has caused extensive pressure on the network where the data flowing through it has increased multifold. Therefore, it becomes our joint responsibility to provide a cost-effective and sustainable security solution for IoT enabled healthcare services. Practitioners can efficiently use this affordable solution compared to the expensive security options available in the commercial market and deploy it over a sliced network. The solution can be implemented by NGOs and federal governments to provide secure and affordable healthcare monitoring services to patients in remote locations. Recommendation for Researchers: Research can take this solution to the next level by integrating artificial intelligence into all the modules. They can augment this solution by making it compatible with the federal government’s data privacy laws. Authentication and encryption modules can be integrated to enhance it further. Impact on Society: COVID has given massive exposure to the healthcare sector since last year. With everything online, data security and privacy is the next most significant concern. This research can be of great support to those working for the security of health care services. This paper provides “Security as a Solution”, which can enhance the security of an otherwise less secure ecosystem. The healthcare use cases discussed in this paper address the most common security issues in the IoT enabled healthcare ecosystem. Future Research: We can enhance this application by including data privacy modules like authentication and authorisation, data encryption and help to abide by the federal privacy laws. In addition, machine learning and artificial intelligence can be extended to other modules of this application. Moreover, this experiment can be easily applicable to many other domains like e-homes, e-offices and many others. For example, e-homes can have devices like kitchen equipment, rooms, dining, cars, bicycles, and smartwatches. Therefore, one can use this application to monitor these devices and detect any suspicious activity.


Sign in / Sign up

Export Citation Format

Share Document