scholarly journals Flavonoid Intakes in the US Diet Are Linked to Higher Socioeconomic Status and to Tea Consumption: Analyses of NHANES 2011–16 Data

2020 ◽  
Vol 150 (8) ◽  
pp. 2147-2155 ◽  
Author(s):  
Florent Vieux ◽  
Matthieu Maillot ◽  
Colin D Rehm ◽  
Adam Drewnowski

ABSTRACT Background Many of the health benefits of tea have been attributed to its flavonoid content. Tea consumption in US adults varies by socioeconomic status (SES). Objectives The present objective was to explore intakes of total flavonoids and flavonoid subclasses by participant sociodemographics and by patterns of tea consumption. Methods The present analyses were based on 2 d of dietary recalls for 17,506 persons aged >9 y in the 2011–2016 NHANES. The What We Eat in America nutrient composition database was merged with the USDA Expanded Flavonoid database, which included total flavonoids and flavan-3-ols (including catechins), flavanones, flavonols, anthocyanidins, flavones, and isoflavones. Flavonoid intakes were compared by sex, age, race/ethnicity, education, and income-to-poverty ratio (IPR) in univariate analyses. Flavonoid intakes of children and adults were also compared by tea consumption status. Time trends in flavonoid intakes were also examined. Results Mean total flavonoid intake was 219 mg/d, of which flavan-3-ols provided 174 mg/d, or 79%. The highest total flavonoid intakes were found in adults aged 51–70 y (293 mg/d), non-Hispanic whites (251 mg/d) and in groups with college education (251 mg/d) and higher income (IPR >3.5: 249 mg/d) (P < 0.001 for all). The socioeconomic gradient was significant for anthocyanidins, flavonols, and flavones (P < 0.001 for all) but not for flavan-3-ols, and persisted across 3 cycles of NHANES. Adult tea consumers had higher intakes of total flavonoids (610 mg/d compared with 141 mg/d) and flavan-3-ols (542 mg/d compared with 97.8 mg/d) than did nonconsumers (P < 0.001). Time trend analyses showed that both tea consumption and flavonoid intakes were unchanged from 2011 to 2016. Conclusions Flavonoid intakes in children and adults in the NHANES 2011–16 sample were associated with higher SES and were largely determined by tea consumption. Studies of diet and disease risk need to take sociodemographic gradients and eating and drinking habits into account.

Circulation ◽  
2015 ◽  
Vol 131 (suppl_1) ◽  
Author(s):  
Margarethe Goetz ◽  
Viola Vaccarino ◽  
Terry Hartman ◽  
Bill McClellan ◽  
Aaron Anderson ◽  
...  

Introduction: Diets rich in plant-based foods have been associated with lower stroke risk. Plant-based foods contain a variety of potentially cardioprotective compounds, including flavonoids. We assessed the hypothesis that total flavonoid and flavonoid subclass intakes are associated with incident ischemic stroke in a population-based cohort oversampled for non-Hispanic blacks and Stroke Belt residents. Methods: Between 2003 and 2007, REGARDS enrolled black and white Americans age ≥ 45 years. Participants were 20,413 men and women who completed a Block 98 food frequency questionnaire (FFQ) and without stroke at baseline. Total flavonoid and flavonoid subclass (anthocyanidin, flavan-3-ol, flavanone, flavonol, flavone, proanthocyanidin and isoflavone) intakes were estimated using the food consumption reported by the FFQ and the flavonoid contents of each food using USDA databases. Incident strokes were captured by participant report and adjudicated by experts. Quintiles of flavonoid intake were examined as predictors of incident stroke using Cox regression models using the first quintile as the referent. Tests for trend used the quintile medians. Results: Adjusting for age and caloric intake, there was a statistically significant inverse association between total flavonoid intake and ischemic stroke (Q5 v Q1: HR=0.68; 95% CI=0.51, 0.90; p-trend=0.04) however, this association weakened after additional adjustment for demographic, socioeconomic and health behavior factors as well as self-reported CHD at baseline (Q5 v Q1: HR=0.77; 95% CI=0.58, 1.03; p-trend=0.31). A similar pattern was seen for flavanones (age, energy adjusted HR=0.74; 95% CI= 0.57, 0.95; p-trend=0.02; fully adjusted HR= 0.82; 95%CI=0.65, 1.05; p-trend=0.06). Effect estimates for total flavonoids, flavanones, proanthocyanidins, and isoflavones, suggested a protective, though nonlinear association with risk reduction emerging at the second quintile, though these did not achieve statistical significance (total flavonoids, fully adjusted HR (95% CI): Q2= 0.80 (0.61, 1.04); Q3= 0.85 (0.65, 1.11); Q4=0.92 (0.70, 1.19); Q5= 0.77 (0.58, 1.03)). Total flavonoid and flavanone intake were significantly associated with IS in fully adjusted models in women (total: Q5 v Q1 HR=0.62; 95% CI= 0.41, 0.94; p-trend=0.15; flavanones HR=0.65; 95% CI=0.44, 0.95; p-trend=0.03) but not in men (total: Q5 v Q1 HR=0.95; 95% CI= 0.63, 1.42; flavanones HR=0.80; 95% CI=0.58, 1.09; p-interaction=0.67). There was no effect modification by race or region of residence. Conclusion: Total dietary flavonoids and flavanones are associated with a reduction in risk of incident ischemic stroke, particularly in women. The emergence of a protective effect at the second quintile for total flavonoids, flavanones, proanthocyanidins and isoflavones is consistent with previous studies of dietary flavonoid intake and CVD mortality.


2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1426-1426
Author(s):  
Kijoon Kim ◽  
Kyungho Ha ◽  
Junichi Sakaki ◽  
Hwayoung Noh ◽  
Ock Chun

Abstract Objectives Diets rich in flavonoids can reduce the risk of developing chronic diseases through their antioxidant and anti-inflammatory properties. While differences in flavonoid intake by race/ethnicity have been previously described, differences between race/ethnicity within categories sociodemographic characteristics have not been fully assessed. Therefore, the objective of this study was to estimate flavonoid intake and evaluate the disparities by race/ethnicity within categories of sociodemographic characteristics in US adults. Methods A total of 15,775 US adults aged 20 years and older in NHANES 2007–2014 were included in this cross-sectional study. Flavonoid intake was calculated by linking food consumption data from a 24-hour diet recall to a flavonoid database which has been expanded on by our research group using the USDA Databases for the Flavonoid (Release 3.3), and Isoflavone (Release 2.1) in addition to the USDA's Expanded Flavonoid Database for the Assessment of Dietary Intakes (Release 1.1). Mean (SE) flavonoid intakes by sociodemographic categories were compared with one-way ANOVA. Results Among US adults, mean (SE) total flavonoid intake was 227.6 (8.0) mg/day, and total flavonoid intake was highest in 40–59 year olds, non-Hispanic whites, those with a poverty-income ratio (PIR) ≥1.85, those with a college education or above, and those married or living with a partner. In most sociodemographic categories, Hispanics consistently had the lowest total flavonoid intakes compared to other races/ethnicities. Among Hispanic subgroups, total flavonoid intake was lowest in men, 20–39 years olds, PIR < 1.3, less than high school education, and single marital status (men only). Ethnic disparities in flavonoid intake were more pronounced between certain sociodemographic subcategories including men, 40–59 year olds, PIR < 1.3, less than high school education, and married marital status (men only). Conclusions These findings indicate that there are significant racial differences in flavonoid intake. Notably, Hispanics tended to have the lowest intake. Certain sociodemographic populations such as males, low income or low educated may be at an increased risk of flavonoid under-consumption. Funding Sources This research received no external funding.


2020 ◽  
Vol 124 (11) ◽  
pp. 1198-1206
Author(s):  
Johanna Rienks ◽  
Katharina J. Penczynski ◽  
Sarah Schmitting ◽  
Anette E. Buyken ◽  
Ute Nöthlings

AbstractFlavonoids are suggested to reduce disease risk. Since dietary habits are acquired during early life, describing age and time trends of flavonoid intake and major food sources are important for monitoring and disease prevention in later life. We aimed to describe total flavonoid intake and food sources and to investigate age and time trends of flavonoid intake in 3–18-year-olds, from the Dortmund Nutritional and Anthropometric Longitudinally Designed study from 1985 to 2016. Intake was assessed annually using 3-d weighed food records (WFR). Flavonoid values were assigned using the United States Department of Agriculture database. Foods contributing to intake were determined. Age and time trends in total flavonoid and isoflavone density were analysed by sex with PROC MIXED. In total, 1312 children completed 10 758 WFR. Across all ages, daily mean total flavonoid density was lower in boys compared with girls (134 v. 146 mg/4184 kJ) and no difference in median isoflavone density (0·04 mg/4184 kJ per d) was found. The top five foods contributing to total flavonoid intake were apple with peel (15·0/17·1 %), strawberries (5·9/6·1 %), chocolate spread (3·9/3·5 %), orange juice (3·5/3·4 %) and pasta (3·5/3·4 %) for boys and girls, respectively. Overall, in boys, total flavonoid density decreased over the course of age and time. In girls, there was no association with age or time. In both sexes, isoflavone density followed a U-shaped age trend with no change over time. From a public health perspective, the overall observed downwards trend of flavonoid intake in boys deserves attention. Future initiatives should be tailored at maintaining a high flavonoid density as children age, specifically among boys.


2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
N Bondonno ◽  
K Murray ◽  
C P Bondonno ◽  
J R Lewis ◽  
K D Croft ◽  
...  

Abstract Background Our understanding of how diet affects future risk of atrial fibrillation (AF) is limited. Evidence suggests that higher habitual intakes of flavonoids, bio-active compounds found in plant-based foods and beverages, lower cardiovascular disease risk, attenuate inflammation, and may have anti-arrhythmic properties. Purpose To investigate the association between flavonoid intake and clinically apparent AF in a large cohort of Danish men and women. Methods Baseline data from 55 634 participants without AF of the Danish Diet, Cancer and Health Study, recruited from 1993 to 1997, were cross-linked with Danish nationwide registries. Flavonoid intake was calculated from validated food frequency questionnaires using the Phenol-Explorer database. Associations between flavonoid intake and AF hospitalisation were examined using restricted cubic splines based on Cox proportional hazards models with adjustments for age, sex, BMI, smoking status, physical activity, alcohol intake, income, and hyperthyroidism. Results After a median [IQR] follow-up of 21 [18–22] years, 6 301 participants were hospitalised with AF. Non-linear associations were observed for total flavonoid intake and for all flavonoid sub-classes. For total flavonoid intake, after adjusting for potential lifestyle confounders and compared to participants in quintile 1 (median intake: 173 mg/day), those in quintile 3 (median intake: 320 mg/day) and quintile 4 (median intake: 494 mg/day) had a significantly lower risk of AF, with hazard ratios (95% CI) of 0.93 (0.87, 0.99) and 0.92 (0.86, 0.98), respectively. Compared to median intake in the lowest quintile, a total flavonoid intake of 1000 mg/day was associated with a lower risk of AF in smokers [0.86 (0.77, 0.96)] but not in non-smokers [0.96 (0.88, 1.05)], a lower risk of AF in high alcohol consumers [>20 g/d: 0.84 (0.75, 0.94)] but not in low-to-moderate alcohol consumers [<20 g/d: 0.97 (0.89, 1.06], a trending lower risk of AF in diabetics [0.76 (0.51, 1.14)] but not in non-diabetics [0.95 (0.89, 1.02)], and a trending lower risk of AF in those with ischaemic heart disease [0.84 (0.65, 1.09)] but not in those without [0.96 (0.89, 1.03), Figure 1]. Figure 1 Conclusion We observed an inverse association between total flavonoid intake and AF, most notably in sub-populations with known lifestyle and disease risk factors for AF. This finding warrants investigation in randomised controlled trials. If confirmed, ensuring the adequate consumption of flavonoid-rich foods, particularly in individuals “at risk”, may be an important strategy to mitigate AF risk. Acknowledgement/Funding The Danish Diet, Cancer, and Health Study was funded by the Danish Cancer Society.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Nader Rajabi Gilan ◽  
Mehdi khezeli ◽  
Shirin Zardoshtian

Abstract Background Life satisfaction is an important component in designing strategies to improve health outcomes in different groups of society. This study aimed to investigate the effect of subjective socioeconomic status (SSS), social capital (SC), self-rated health (SRH), and physical activity (PA) on life satisfaction (LS) in Iran. Methods This cross-sectional study was conducted on 1187 people (643 men and 544 women) lived in five western cities in Iran. The sampling method was multistage clustering. Data collection tool was a five part questionnaire including demographic characteristics, socioeconomic status ladder, social capital scale, a question to measure physical activity, and the life satisfaction scale. Data were analyzed using independent t-test, one way ANOVA, and Ordinal Logistic Regression. Result Life satisfaction was higher in married men and women compared to single and widows (p < 0.05). Among the variables included in the main model, the significant predictors were college education (− 0.500), marriage (coefficient = 0.422), age 25–34 years (coefficient = − 0.384), SRH (coefficient = 0.477), male sex (coefficient = 0.425), SSS (coefficient = 0.373), trust (coefficient = 0.115), and belonging and empathy (coefficient = 0.064). Conclusion SRH and SSS were significant predictors of life satisfaction in west Iranian society. Being married was associated with higher LS, but college education affects LS adversely.


2015 ◽  
Vol 9 (7) ◽  
pp. e0003937 ◽  
Author(s):  
Mariana Kikuti ◽  
Geraldo M. Cunha ◽  
Igor A. D. Paploski ◽  
Amelia M. Kasper ◽  
Monaise M. O. Silva ◽  
...  

Author(s):  
Amrita Behel ◽  
Leena Raje

Background: Menarche, one of the most reliable markers of pubertal maturity, is a result of a complex interplay between genetic and environmental factors. Since accelerated pubertal development is an important determinant of prognostic disease risk, especially in developing countries, attention must be focused on this important public health aspect.  Methods: Total 200 school-going girls aged between 10-15 years studying in municipal, public-funded and private schools in Mumbai were included in the study based on the inclusion criteria of having attained menarche only in the last three months. Sociodemographic and anthropometric details were collected using a structured schedule and physical activity data was collected using the physical activity questionnaire for older children and adolescents.Results: Socioeconomic status and family size were found to significantly influence the age of onset of menarche (p<0.001). Anthropometric indices of height, weight and BMI were found to have significant negative correlations indicating that taller, heavier girls reached menarche earlier than their shorter and lighter peers (p<0.000). Level of physical activity was also found to be an important contributing factor to age at menarche such that a higher level of physical activity was observed in girls with higher mean menarcheal age (p<0.000).  Conclusions: Age at menarche was found to be influenced by factors such as socioeconomic status, BMI and physical activity.   


Author(s):  
Mersy T Tanamal ◽  
Pamella Mercy Papilaya ◽  
Alwi Smith

Background: The village of Latuhalat and Kayu Putih village is a place that is on the beach and in the mountains. Potential natural resources are quite a lot of plants melinjo (Gnetum gnemon L). This study aims to determine the total compound of flavonoid content of leaf melinjo (Gnetum gnemon L) based on place difference. Method: The method used in this study using the method of Chang et al. The solvent used for diluting the melinjo extract was methanol solvent, then measured using a UV-VIS spectrophotometer. Result: Result of analysis of flavonoid compound content, Latuhalat Village has average total flavonoid content of13.080% and average total flavonoid content in Kayu Putih Village equal to 17.028%. Kayu Putih Village has more flavonoid compound than Latuhalat Village. Conclusion: Total levels of melinjo leaf flavonoids (Gnetum gnemon L) in Kayu Putih Village were more than total flavonoids of leaf melinjo (Gnetum gnemon L) in Latuhalat Village.


Author(s):  
Jennifer Larisa Liem ◽  
Maria Marina Herawati

Flavonoid compound is an important compound of tea products. However, the flavonoid level content in black tea is lowest than other teas. This is due to the processing of black tea which has an enzymatic oxidation stage and  the tea age leaves when picking. Young tea leaves contain higher total flavonoids than old tea leaves. With an average level of total flavonoids, the young tea leaves is 27.76% qe w / w, while for the old tea leaves 18.61% qe w / w. However, the enzymatic oxidation time treatment did not affect the total flavonoids because the process only affected the quality of black tea steeping, on it’s colour, aroma, and taste. Keywords: age of tea leaves, black tea, enzymatic oxidation, total flavonoids


Sign in / Sign up

Export Citation Format

Share Document