Cancer Registries

2019 ◽  
pp. 17-24
Author(s):  
Sabine Siesling ◽  
Freddie Bray ◽  
Roberto Zanetti ◽  
Tomohiro Matsuda ◽  
Anna Gavin ◽  
...  
Keyword(s):  
Control Strategies ◽  
Essential Element ◽  
Cancer Control ◽  
Population Level ◽  
Cancer Registries ◽  
Developed Countries ◽  
Epidemiological Studies ◽  
Vital Role ◽  
Treatment Modalities ◽  
Potential Hazard

Abstract: Cancer registries provide insight into the burden of cancer by systematically recording data on new (pre)malignancies and/or in-situ tumours within a specific region, area, or treatment setting (e.g. hospital-based care). An understanding of the burden for a patient group at the population level is given by indicators such as incidence, survival, treatment modalities and timing, and prevalence. Mortality data are often obtained through national or regional death registries. Registries play a vital role in research into the causes of cancer, both by providing data on patterns and trends, and in different types of epidemiological studies (in particular, in their ability to follow up groups of persons exposed to a potential hazard). They comprise an essential element in the planning and monitoring of cancer control strategies as well as for identifying priorities in public health. Increasingly, registries in developed countries have begun to gather more data on treatments and outcomes (such as recurrences), which can be used for monitoring quality of care, guideline adherence, and outcome research.

scholarly journals The state of cancer in Meru, Kenya: a retrospective study

2019 ◽  
Vol 2 ◽  
pp. 167
Author(s):  
Francis Kobia ◽  
Jesse Gitaka ◽  
Francis Makokha ◽  
Moses Kamita ◽  
Joshua Kibera ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Stomach Cancer ◽  
Control Strategies ◽  
Cancer Control ◽  
Cancer Registries ◽  
The State ◽  
Cancer Type ◽  
African Countries ◽  
Low Middle Income Countries ◽  
Cancer Rates

Background: It is projected that by 2030, 70% of all cancer related deaths will occur in low-middle income countries. However, data on the state of cancer in most African countries is scanty. Cancer estimates for Kenya are based on the Nairobi and Eldoret cancer registries, leaving most parts of the country unrepresented. Lacking national coverage, these data do not accurately reflect Kenya’s cancer burden. The paucity of reliable data impedes formulation of effective cancer control strategies and cancer research prioritization. Here, we report the findings of a retrospective study of the cancer state in Meru County, Kenya. Methods: A retrospective analysis of patient files at Meru hospice was carried out. 2349 cancer cases seen at the Meru hospice between 2003 and 2018 were analyzed. Data abstracted from the records included patient age, gender and cancer type. The abstracted data was analyzed by descriptive statistics. Results: Our results indicate that cancer is almost evenly distributed across genders, with men accounting for 49% and women 51%. Stomach cancer rates are strikingly elevated and equal to those in countries with the highest stomach cancer rates globally – making it the commonest cancer in this region (14%). Among men, the most common cancers affect the prostate (18%), stomach (17%), esophagus (14%), head & neck (12%), liver (8%) and colorectum (5%). Among women, the commonest are cancers of the breast (22%), cervix (20%), stomach (11%), esophagus (8%), head & neck (6%) and liver (5%). Breast cancer occurs at a notably early age, with 20% of those affected aged below 40. Lung cancer rates are notably low in this region (1.3%) relative to world estimates. Conclusion: Cancer distribution in Meru is nearly even between sexes. Our analysis suggests that the Meru region is a stomach cancer hotspot and that it also experiences elevated esophageal cancer levels.

scholarly journals Vitamin D Deficiency in Pregnant Women and Newborn

2021 ◽  
Author(s):  
Neelakanta Kanike ◽  
Naveen Kannekanti ◽  
Jenny Camacho
Keyword(s):  
Vitamin D ◽  
Pregnant Women ◽  
Vitamin D Deficiency ◽  
Respiratory Infections ◽  
Type I Diabetes ◽  
Essential Element ◽  
Population Level ◽  
Developed Countries ◽  
Hormone Deficiency ◽  
Vitamin D Status

Vitamin-D is not only an essential element in bone health, but it is also a pro-hormone. Deficiency of vitamin D is the most common cause of rickets and is also known to increase the risk of respiratory distress syndrome, lower respiratory infections, food sensitivities, asthma, type I diabetes, autism and schizophrenia. Vitamin D deficiency limits the effective absorption of dietary calcium and phosphorus. Vitamin D status in newborns is entirely dependent on maternal supply during pregnancy. Low maternal vitamin D status during pregnancy is a major risk factor for rickets in infants. Rickets in children is caused by severe, chronic vitamin D deficiency with apparent skeletal abnormalities, but neonates with vitamin D insufficiency have no overt skeletal or calcium metabolism defects. Rickets was a global disease in the early twentieth century. It has nearly disappeared in developed countries after its causal pathway was understood and fortification of milk with the hormone vitamin D was introduced at the population level. Surprisingly, rickets is re-emerging per recent evidence. Vitamin D deficiency is prevalent in both developed and developing countries. The chapter will review the prevalence of vitamin D deficiency in pregnant women and newborn population and its adverse effects on pregnancy and infant’s health. The chapter also describes evidence-based recommendations to prevent vitamin D deficiency in these vulnerable population.

scholarly journals The pertussis enigma: reconciling epidemiology, immunology and evolution

2016 ◽  
Vol 283 (1822) ◽  
pp. 20152309 ◽  
Author(s):  
Matthieu Domenech de Cellès ◽  
Felicia M. G. Magpantay ◽  
Aaron A. King ◽  
Pejman Rohani
Keyword(s):  
Control Strategies ◽  
Natural Infection ◽  
Population Level ◽  
Developed Countries ◽  
Effective Control ◽  
Simple Explanation ◽  
Incidence Data ◽  
High Infection ◽  
Pertussis Epidemiology

Pertussis, a highly contagious respiratory infection, remains a public health priority despite the availability of vaccines for 70 years. Still a leading cause of mortality in developing countries, pertussis has re-emerged in several developed countries with high vaccination coverage. Resurgence of pertussis in these countries has routinely been attributed to increased awareness of the disease, imperfect vaccinal protection or high infection rates in adults. In this review, we first present 1980–2012 incidence data from 63 countries and show that pertussis resurgence is not universal. We further argue that the large geographical variation in trends probably precludes a simple explanation, such as the transition from whole-cell to acellular pertussis vaccines. Reviewing available evidence, we then propose that prevailing views on pertussis epidemiology are inconsistent with both historical and contemporary data. Indeed, we summarize epidemiological evidence showing that natural infection and vaccination both appear to provide long-term protection against transmission and disease, so that previously infected or vaccinated adults contribute little to overall transmission at a population level. Finally, we identify several promising avenues that may lead to a consistent explanation of global pertussis epidemiology and to more effective control strategies.

scholarly journals Introduction to the Cancer Intervention and Surveillance Modeling Network (CISNET) Breast Cancer Models

2018 ◽  
Vol 38 (1_suppl) ◽  
pp. 3S-8S ◽  
Author(s):  
Oguzhan Alagoz ◽  
Donald A. Berry ◽  
Harry J. de Koning ◽  
Eric J. Feuer ◽  
Sandra J. Lee ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Control Strategies ◽  
Cancer Control ◽  
Population Level ◽  
Breast Cancer Outcomes ◽  
Detection Technology ◽  
Cancer Models ◽  
Incidence And Mortality ◽  
Cancer Intervention ◽  
The Impact

The Cancer Intervention and Surveillance Modeling Network (CISNET) Breast Cancer Working Group is a consortium of National Cancer Institute–sponsored investigators who use statistical and simulation modeling to evaluate the impact of cancer control interventions on long-term population-level breast cancer outcomes such as incidence and mortality and to determine the impact of different breast cancer control strategies. The CISNET breast cancer models have been continuously funded since 2000. The models have gone through several updates since their inception to reflect advances in the understanding of the molecular basis of breast cancer, changes in the prevalence of common risk factors, and improvements in therapy and early detection technology. This article provides an overview and history of the CISNET breast cancer models, provides an overview of the major changes in the model inputs over time, and presents examples for how CISNET breast cancer models have been used for policy evaluation.

scholarly journals Global burden of oesophageal and gastric cancer by histology and subsite in 2018

Gut ◽  
2020 ◽  
Vol 69 (9) ◽  
pp. 1564-1571 ◽  
Author(s):  
Melina Arnold ◽  
Jacques Ferlay ◽  
Mark I van Berge Henegouwen ◽  
Isabelle Soerjomataram
Keyword(s):  
Gastric Cancer ◽  
Control Strategies ◽  
Cancer Control ◽  
Cancer Registries ◽  
Population Based ◽  
Incidence Rates ◽  
Oesophageal Adenocarcinoma ◽  
Global Burden ◽  
Eastern Asia ◽  
Using Data

ObjectivesTo provide updated estimates of the global burden of oesophageal and gastric cancer by subsite and type.MethodsUsing data from population-based cancer registries, proportions of oesophageal adenocarcinoma (OAC) and squamous cell carcinoma (OSCC) out of all oesophageal as well as cardia gastric cancer (CGC) and non-CGC (NCGC) out of all gastric cancer cases were computed by country, sex and age group. Proportions were subsequently applied to the estimated numbers of oesophageal and gastric cancer cases from GLOBOCAN 2018. Age-standardised incidence rates (ASR) were calculated.ResultsIn 2018, there were an estimated 572 000 new cases of oesophageal cancer worldwide, 85 000 OACs (ASR 0.9 per 100 000, both sexes combined) and 482 000 OSCCs (ASR 5.3). Out of 1.03 million gastric cancers, there were an estimated 181 000 cases of CGC (ASR 2.0) and 853 000 cases of NCGC (ASR 9.2). While the highest incidence rates of OSCC, CGC and NCGC were observed in Eastern Asia (ASRs 11.1, 4.4 and 17.9, respectively), rates of OAC were highest in Northern Europe (ASR 3.5). While globally OSCC and NCGC remain the most common types of oesophageal and gastric cancer, respectively, rates of OAC exceed those of OSCC in an increasing number of high-income countries.ConclusionsThese updated estimates of the global burden of oesophageal and gastric cancer by subtype and site suggest an ongoing transition in epidemiological patterns. This work will serve as a cornerstone for policy-making and will aid in developing appropriate cancer control strategies.

Novel Coronavirus SARS-CoV-2 (COVID-19) and Pregnancy: A hypothetical view

2020 ◽  
Vol 20 ◽  
Author(s):  
Ahmed RG
Keyword(s):  
Immune System ◽  
Cellular Therapy ◽  
Early Stage ◽  
Control Strategies ◽  
Vital Role ◽  
Healthy Life ◽  
Global Pandemic ◽  
Maternal Immune System ◽  
Perinatal Management ◽  
Novel Coronavirus

Background: The complications of the SARS-CoV-2 infection and its COVID-19 disease on mothers and their offspring are less known. Objective: The aim of this review was to determine the transmission, severity, complications of SARS-CoV-2 infection during the pregnancy. This review showed the influence of COVID-19 disease on the neonatal neurogenesis. Owing to no specific vaccines or medicines that were reported for the treatment of COVID-19 disease, this review suggested some control strategies like treatments (medicinal plants, antiviral therapy, cellular therapy, and immunotherapy), nutrition uptake, prevention, and recommendations. Discussion: This overview showed in severely states that SARS-CoV-2 infection during the early stage of pregnancy might increase the risk of stress, panic, and anxiety. This disorder can disturb the maternal immune system, and thus causing a neurodevelopmental disturbance. This hypothesis may be depending on the severity and intensity of the SARS-CoV-2 infection during pregnancy. However, vertical transmission of SARS-CoV-2 from dams to their fetuses is absent until now. Conclusion: During this global pandemic disease, maintaining safety during pregnancy, vaginal delivery, and breastfeeding may play a vital role in a healthy life for the offspring. Thus, international and national corporations should be continuing for perinatal management, particularly during the next pandemic or disaster time.

Trends in the incidence and mortality of oral cancer in Nevada (Preprint)

2020 ◽  
Author(s):  
Kevin Foote ◽  
Karl Kingsley
Keyword(s):  
Public Health ◽  
Oral Cancer ◽  
Cancer Incidence ◽  
Cancer Control ◽  
Cancer Registries ◽  
Public Health Research ◽  
Chi Square ◽  
Incidence And Mortality ◽  
The Us ◽  
Chi Square Analysis

BACKGROUND Reviews of national and state-specific cancer registries have revealed differences in rates of oral cancer incidence and mortality that have implications for public health research and policy. Many significant associations between head and neck (oral) cancers and major risk factors, such as cigarette usage, may be influenced by public health policy such as smoking restrictions and bans – including the Nevada Clean Indoor Act of 2006 (and subsequent modification in 2011). OBJECTIVE Although evaluation of general and regional advances in public policy have been previously evaluated, no recent studies have focused specifically on the changes to the epidemiology of oral cancer incidence and mortality in Nevada. METHODS Cancer incidence and mortality rate data were obtained from the National Cancer Institute (NCI) Division of Cancer Control and Population Sciences (DCCPS) Surveillance, Epidemiology and End Results (SEER) program. Most recently available rate changes in cancer incidence and mortality for Nevada included the years 2012 – 2016 and are age-adjusted to the year 2000 standard US population. Comparisons of any differences between Nevada and the overall US population were evaluated using Chi square analysis. RESULTS This analysis revealed that the overall rates of incidence and mortality from oral cancer in Nevada differs from that observed in the overall US population. For example, although the incidence of oral cancer among Caucasians is increasing in Nevada and the US overall, it is increasing at nearly twice that rate in Nevada, P=0.0002. In addition, although oral cancer incidence among Minorities in the US is declining, it is increasing in Nevada , P=0.0001. Analysis of reported mortality causes revealed that mortality from oral cancer increased in the US overall but declined in Nevada during the same period (2012-2016). More specifically, mortality among both Males and Females in the US is increasing, but is declining in Nevada, P=0.0027. CONCLUSIONS Analysis of the epidemiologic data from Nevada compared with the overall US revealed significant differences in rates of oral cancer incidence and mortality. More specifically, oral cancer incidence increased in Nevada between 2012-2016 among all groups analyzed (Males, Females, White, Minority), while decreases were observed nationally among Females and Minorities. Although mortality in Nevada decreased over this same time period (in contrast to the national trends), the lag time between diagnosis (incidence) and mortality suggests that these trends will change in the near future. CLINICALTRIAL Not applicable

scholarly journals A New Variant among Newcastle Disease Viruses Isolated in the Democratic Republic of the Congo in 2018 and 2019

Viruses ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 151
Author(s):  
Augustin T. Twabela ◽  
Lam Thanh Nguyen ◽  
Justin Masumu ◽  
Patrick Mpoyo ◽  
Serge Mpiana ◽  
...  
Keyword(s):  
Newcastle Disease ◽  
Democratic Republic ◽  
Control Strategies ◽  
Farming Systems ◽  
Epidemiological Studies ◽  
Comprehensive Knowledge ◽  
Current Vaccine ◽  
New Variant ◽  
Control And Prevention ◽  
Republic Of The Congo

Newcastle disease (ND) is a highly transmissible and devastating disease that affects poultry and wild birds worldwide. Comprehensive knowledge regarding the characteristics and epidemiological factors of the ND virus (NDV) is critical for the control and prevention of ND. Effective vaccinations can prevent and control the spread of the NDV in poultry populations. For decades, the Democratic Republic of the Congo (DRC) has reported the impacts of ND on commercial and traditional poultry farming systems. The reports were preliminary clinical observations, and few cases were confirmed in the laboratory. However, data on the phylogenetic, genetic, and virological characteristics of NDVs circulating in the DRC are not available. In this study, the whole-genome sequences of three NDV isolates obtained using the next-generation sequencing method revealed two isolates that were a new variant of NDV, and one isolate that was clustered in the subgenotype VII.2. All DRC isolates were velogenic and were antigenically closely related to the vaccine strains. Our findings reveal that despite the circulation of the new variant, ND can be controlled in the DRC using the current vaccine. However, epidemiological studies should be conducted to elucidate the endemicity of the disease so that better control strategies can be implemented.

Global Oral Health Inequalities

2011 ◽  
Vol 23 (2) ◽  
pp. 227-236 ◽  
Author(s):  
S. Challacombe ◽  
M. Chidzonga ◽  
M. Glick ◽  
T. Hodgson ◽  
M. Magalhães ◽  
...  
Keyword(s):  
Oral Health ◽  
Sexually Transmitted Diseases ◽  
Fungal Infections ◽  
Developed Countries ◽  
Epidemiological Studies ◽  
Current Treatment ◽  
Health Priorities ◽  
Oral Manifestations ◽  
Sexually Transmitted ◽  
Mucosal Involvement

Four oral mucosal infections were identified as Global Oral Health Priorities: (a) HIV and associated viral, bacterial, and fungal infections; (b) tuberculosis; (c) NOMA; and (d) sexually transmitted diseases. Huge global inequalities exist in all four. HIV-associated infections constitute the major challenge. Oral manifestations of AIDS can be specifically diagnostic, indicating a significant role for dentists within health teams. The World Workshops in Oral Health & Disease in AIDS have identified a research program, elements of which are being implemented. Data on oral mucosal involvement in tuberculosis, syphilis, and gonorrhea are incomplete in developed countries and virtually non-existent in low- and middle-income countries, indicating the need for further epidemiological studies. Oral manifestations of tuberculosis and sexually transmitted diseases are largely associated with general health, so action programs should be integrated with agencies treating the systemic diseases. NOMA is very much in the oral health domain. It is a preventable disease associated with malnutrition and unidentified bacterial factors. Prevalence is probably grossly overestimated at present; but nevertheless it constitutes a challenge to the profession, especially in the NOMA belt. Current treatment is surgical, but plans for its eradication should be achievable. The global oral health community, especially the IADR, has a major role to play.

Clarifying Institutional and Organizational Conditions Promoting Principals' Quality Leadership and Reform Design for Japan

Impact ◽  
2021 ◽  
Vol 2021 (7) ◽  
pp. 15-17
Author(s):  
Hirofumi Hamada
Keyword(s):  
Education Reform ◽  
Developed Countries ◽  
Vital Role ◽  
Quality Of Education ◽  
Organizational Conditions ◽  
Problem Situations ◽  
Distributed Approach ◽  
Area Of Interest ◽  
High Level

Education reform helps ensure that the education in a given country is of the highest possible quality and is a key area of focus for many developed countries. Japan's education system rates highly and the evolution of education reform is key to ensuring this high level is sustained. School principals play a key role in delivering high-quality education and, indeed, a school principal's leadership correlates with the quality of education available. This is an area of interest for Professor Hirofumi Hamada, School Management Laboratory in the Faculty of Human Sciences, University of Tsukuba, Japan, who is currently exploring the institutional and organisational conditions that affect the leadership of principals. The goal of this research is to help shape education reform in Japan. Hamada believes it is necessary to create an environment of independent and collaborative learning and to value the individuality of children. In addition, problem situations among children are diverse and complex and how schools respond influences the quality of education. Given that the principal is in charge of how a school is run, they play a vital role in assuring the quality of education. Key to Hamada's work is the idea that principals can share their knowledge and leadership with teachers and this creates an environment of shared leadership. He believes that empowering teachers and encouraging them to take on leadership duties is essential. He is working to inform educators that schools require the leadership of principals and for principals to promote a distributed approach to leadership.

Sign in / Sign up

Export Citation Format

Share Document