Study on Physicochemical Properties of the Carbonated Hydroxyapatite Bone Cement

2007 ◽  
Vol 280-283 ◽  
pp. 1545-1548
Author(s):  
Li Min Dong ◽  
Chen Wang ◽  
Jie Mo Tian ◽  
Jian Pan ◽  
Qing Feng Zan
Keyword(s):  
Compressive Strength ◽  
Phase Composition ◽  
Physicochemical Properties ◽  
Bone Cement ◽  
Pore Size ◽  
Setting Time ◽  
Mineral Phase ◽  
Carbonated Hydroxyapatite ◽  
Natural Bone ◽  
Ft Ir

Carbonated hydroxyapatite (CHA) bone cement is capable of self-setting and has the component similar to the mineral phase of natural bone. But it is compact in structure and short of cavity, which limits new bone growing into CHA bone cement. In this paper, the foaming method was adopted to prepare the porous CHA. The setting time, compressive strength, porosity and pore size of the CHA were examined. The phase composition of the CHA was tested with XRD and FT-IR. The microstructure of the CHA was observed with SEM. The results show that setting time of 7~19 minutes, compressive strength of 26~32MPa, pore size of 100~200µm, porosity of 50~60%.

scholarly journals Enhancing the mechanical properties and cytocompatibility of magnesium potassium phosphate cement by incorporating oxygen-carboxymethyl chitosan

2020 ◽  
Author(s):  
Changtian Gong ◽  
Shuo Fang ◽  
Kezhou Xia ◽  
Jingteng Chen ◽  
Liangyu Guo ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Compressive Strength ◽  
Physicochemical Properties ◽  
Bone Cement ◽  
Ph Value ◽  
Setting Time ◽  
Potassium Phosphate ◽  
Carboxymethyl Chitosan ◽  
Bioactive Substances ◽  
Magnesium Potassium Phosphate Cement

Abstract Incorporating bioactive substances into synthetic bioceramic scaffolds is challenging. In this work, oxygen-carboxymethyl chitosan (O-CMC), a natural biopolymer that is nontoxic, biodegradable and biocompatible, was introduced into magnesium potassium phosphate cement (K-struvite) to enhance its mechanical properties and cytocompatibility. This study aimed to develop O-CMC/magnesium potassium phosphate composite bone cement (OMPC), thereby combining the optimum bioactivity of O-CMC with the extraordinary self-setting properties and mechanical intensity of the K-struvite. Our results indicated that O-CMC incorporation increased the compressive strength and setting time of K-struvite and decreased its porosity and pH value. Furthermore, OMPC scaffolds remarkably improved the proliferation, adhesion and osteogenesis related differentiation of MC3T3-E1 cells. Therefore, O-CMC introduced suitable physicochemical properties to K-struvite and enhanced its cytocompatibility for use in bone regeneration.

Mechanical Property of Phosphoaluminate Cement

2010 ◽  
Vol 150-151 ◽  
pp. 1754-1757 ◽  
Author(s):  
Peng Liu ◽  
Zhi Wu Yu ◽  
Ling Kun Chen ◽  
Zhu Ding
Keyword(s):  
Mechanical Property ◽  
Compressive Strength ◽  
Phase Composition ◽  
Electrical Properties ◽  
Pore Size Distribution ◽  
Pore Size ◽  
High Strength ◽  
Curing Time ◽  
Hydration Products ◽  
Resistance Value

The influence of curing time on the mechanical property of the phosphoaluminate cement (PAC) was investigated, and the mechanism was discussed as well. The phase composition and morphology of hydration products, electrical properties, porosity and pore size distribution of PAC cured different age were analyzed with XRD, EIS and MIP. The results showed PAC has the property of early-high strength, and the compressive strength of PAC cured for 1 day was about 70% of 28 days’. The main hydration products of PAC are micro-crystal phase and gel of phosphate and phosphoaluminate which formed compacter microstructure. In addition, there are no calcium hydroxide (CH) and ettringite (AFt) produced during the process of hydration. The compressive strength of PAC increased with age, which was due to more products continuously produced. The ac resistance analysis manifested as the change of the nyquist pattern and resistance value.

Development of Novel Bioactive PMMA-Based Bone Cement and its In Vitro and In Vivo Evaluation

2006 ◽  
Vol 309-311 ◽  
pp. 801-804 ◽  
Author(s):  
S.B. Cho ◽  
Akari Takeuchi ◽  
Ill Yong Kim ◽  
Sang Bae Kim ◽  
Chikara Ohtsuki ◽  
...  
Keyword(s):  
Mechanical Property ◽  
Compressive Strength ◽  
Bone Cement ◽  
The Novel ◽  
In Vivo Evaluation ◽  
Natural Bone ◽  
Pmma Bone Cement ◽  
Rabbit Tibia

In order to overcome the disadvantage of commercialized PMMA bone cement, we have developed novel PMMA-based bone cement(7P3S) reinforced by 30 wt.% of bioactive CaO-SiO2 gel powders to induce the bioactivity as well as to increase mechanical property for the PMMA bone cement. The novel 7P3S bone cement hardened after mixing for about 7 minutes. For in vitro evaluation, apatite forming ability of it was investigated using SBF. When the novel 7P3S bone cement was soaked into SBF, it formed apatite on its surfaces within 1 week Furthermore; there is no decrease in its compressive strength within 9 weeks soaking in SBF. It is though that hardly decrease in compressive strength of 7P3S bone cement in SBF is due to the relative small amount of gel powder or its spherical shape and monosize. In vivo evaluation of the novel 7P3S bone cement was carried out using rabbit. After implantion into rabbit tibia for several periods, the interface between novel bone cement and natural bone was evaluated by CT images. According to the results, the novel bone cement directly contact to the natural bone without fibrous tissue after implantation for 4 weeks. This results indicates that the newly developed 7P3S bone cement can bond to the living bone and also be effectively used as bioactive bone cement without decrease in mechanical property.

scholarly journals A Novel Fast-Setting Strontium-Containing Hydroxyapatite Bone Cement With a Simple Binary Powder System

2021 ◽  
Vol 9 ◽  
Author(s):  
Lijuan Sun ◽  
Tongyang Li ◽  
Sen Yu ◽  
Mengmeng Mao ◽  
Dagang Guo
Keyword(s):  
Compressive Strength ◽  
Bone Cement ◽  
Setting Time ◽  
Synthesis Temperature ◽  
Transformation Rate ◽  
Step Method ◽  
Cement Powder ◽  
Calcium Phosphate Bone Cement ◽  
One Step ◽  
Application Potential

In recent years, strontium-substituted calcium phosphate bone cement (Sr-CPC) has attracted more and more attentions in the field of bone tissue repair due to its comprehensive advantages of both traditional CPC and Sr ions. In this study, a crucial Sr-containing α-Ca3–xSrx(PO4)2 salt has been synthesized using a simplified one-step method at lower synthesis temperature. A novel Sr-CPC has been developed based on the simple binary Sr-containing α-Ca3–xSrx(PO4)2/Ca4(PO4)2O cement powder. The physicochemical properties and hydration mechanism of this Sr-CPC at various Sr contents were intensively investigated. The setting product of this Sr-CPC after a set for 72 h is a single-phase Sr-containing hydroxyapatite, and its compressive strength slightly decreased and its setting time extended with the increase of Sr content. The hydration process included the initial formation of the medium product CaHPO4⋅2H2O (30 min∼1 h), the following complete hydration of Ca4(PO4)2O and the initially formed CaHPO4⋅2H2O (2∼6 h), and the final self-setting of α-Ca3–xSrx(PO4)2 (6 h∼). The compressive strength of Sr-CPC, which was closely related to the transformation rate of Sr-containing hydroxyapatite, tended to increase with the extension of hydration time. In addition, Sr-CPC possessed favorable cytocompatibility and the effect of Sr ions on cytocompatibility of Sr-CPC was not obvious at low Sr contents. The present study suggests α-Ca3–xSrx(PO4)2 is a kind of vital Sr-containing salt source which is useful to develop some novel Sr-containing biomaterials. In addition, the new Sr-containing cement system based on this simple binary α-Ca3–xSrx(PO4)2/Ca4(PO4)2O cement powder displayed an attractive clinical application potential in orthopedics.

scholarly journals New Hybrid Bioactive Composites for Bone Substitution

Processes ◽  
2020 ◽  
Vol 8 (3) ◽  
pp. 335 ◽  
Author(s):  
Anna Ślósarczyk ◽  
Joanna Czechowska ◽  
Ewelina Cichoń ◽  
Aneta Zima
Keyword(s):  
Phase Composition ◽  
Physicochemical Properties ◽  
Mechanical Strength ◽  
Organic Materials ◽  
Setting Time ◽  
Bone Substitutes ◽  
Bone Implant ◽  
Load Bearing ◽  
Implant Materials ◽  
Bioactive Composites

Recently, intensive efforts have been undertaken to find new, superior biomaterial solutions in the field of hybrid inorganic–organic materials. In our studies, biomicroconcretes containing hydroxyapatite (HAp)–chitosan (CTS) granules dispersed in an α tricalcium phospahate (αTCP) matrix were investigated. The influence of CTS content and the size of granules on the physicochemical properties of final bone implant materials (setting time, porosity, mechanical strength, and phase composition) were evaluated. The obtained materials were found to be promising bone substitutes for use in non-load bearing applications.

Preliminary Investigation of Bone Cement Using Calcium Phosphate Glass

2005 ◽  
Vol 284-286 ◽  
pp. 109-112 ◽  
Author(s):  
Byung Hyun Lee ◽  
Min Chul Kim ◽  
Kyoung Nam Kim ◽  
Kwang Mahn Kim ◽  
Seong Ho Choi ◽  
...  
Keyword(s):  
Compressive Strength ◽  
Calcium Phosphate ◽  
Phosphate Glass ◽  
Setting Time ◽  
Preliminary Investigation ◽  
Distilled Water ◽  
Liquid Ratio ◽  
Ft Ir ◽  
Kinetics Of Dissolution ◽  
Kinetics Of

The mixed pastes of binary calcium phosphate glass with Ca/P ratio of 0.6 and distilled water were set after about 4 hr, while never set when calcium phosphate glass with Ca/P lower than 0.5. Their compressive strength was ranged from 16.0 to 23.3 MPa. When Na2HPO4 solution was used instead of distilled water as liquid phase, the setting time became drastically much shorter. As the mole concentration of Na2HPO4 solution increased from 0.25 M to 2 M, setting time was shortened to 35 min from almost 3 hr, but compressive strength decreased from 28.8 MPa to 13.2 MPa. At constant mole concentration, as the mass ratio of a powder to liquid ratio increased, setting time was shortened and maximum compressive strength was measured when a powder/liquid ratio was 2.5. However, no crystallized phases were detected either during setting or after complete setting. The XRD , FT-IR and SEM examinations indicated that calcium phosphate glass dissolved and then glass phase precipitated again. We concluded, therefore, that Na2HPO4 just affected the kinetics of dissolution and precipitation of CPG. The mechanism of hardening has yet to be studied.

Biodentine: um substituto ao MTA?

2019 ◽  
Vol 9 (3) ◽  
pp. 29-36
Author(s):  
Maíra do Prado ◽  
Carolina Oliveira de Lima ◽  
Hugo Gonçalves Dutra ◽  
Jefferson Marion ◽  
Maria Das Graças Afonso Miranda Chaves ◽  
...  
Keyword(s):  
Compressive Strength ◽  
Bond Strength ◽  
Physicochemical Properties ◽  
Calcium Silicate ◽  
Setting Time ◽  
Filling Material ◽  
Retrograde Filling

Objetivo: o objetivo desse estudo é realizar uma revisão de literatura em relação às propriedades físico- -químicas e biológicas do Biodentine, seu emprego na Endodontia e discutir, com base nas evidências científicas encontradas na literatura, se esse material poderá ser um substituto ao MTA. Métodos: foi realizada uma busca na literatura na base de dados PubMed, usando os termos em inglês: Biodentine, calcium silicate, MTA, properties, setting time, radiopacity, solubility, physicochemical properties, porosity, hydration, biocompatibility, bioactivity, microhardness, compressive strength, bond strength, irrigants, furcal perforation, retrograde filling material, revitalization, revascularization, endodontics, apexification. Cinquenta artigos foram incluídos. Resultados: os artigos revisados sugerem que o Biodentine tem características favoráveis e que tem alcançado resultados promissores em relação ao MTA. Conclusão: o Biodentine pode ser considerado um eventual substituto ao MTA.

Evaluation of setting time and compressive strength of a new bone cement precursor powder containing Mg–Na–Ca

2018 ◽  
Vol 232 (10) ◽  
pp. 1017-1024 ◽  
Author(s):  
Mohammad Hossein Esnaashary ◽  
Hamid Reza Rezaie ◽  
Alireza Khavandi ◽  
Jafar Javadpour
Keyword(s):  
Compressive Strength ◽  
Bone Cement ◽  
Setting Time ◽  
Precursor Powder ◽  
Effective Parameters ◽  
X Ray Diffraction ◽  
Liquid Ratio ◽  
X Ray ◽  
The One ◽  
Kinetics Of

Taking the advantage of a novel magnesium phosphate precursor containing Na and Ca, the cementation rate of the cement, including only Mg/Mg–Na–Ca, was studied. Besides, two effective parameters, that is, calcination temperature, 650 °C and 800 °C, and powder-to-cement liquid ratio, 1 and 1.5 g/mL, were assessed. X-ray diffraction, scanning electron microscopy, ion chromatography, particle size analyser, Vicat needle and compression test were used to characterize the powders and obtained cements. The sample containing Mg–Na–Ca, calcined at 800 °C with powder-to-cement liquid ratio of 1.5, obtained the highest compressive strength, 20 MPa, but set fast. To control the kinetics of cementation, the powder containing Mg–Na–Ca calcined at 950 °C with powder-to-cement liquid ratio of 1.5 and 2 g/mL was assessed and the one with 2 g/mL set in 9 min possessing 22 MPa compressive strength was selected as optimal condition to be used as a candidate, injectable bone cement.

Radiopaque acrylic bone cement with bromine-containing acrylic monomer. II

e-Polymers ◽  
2009 ◽  
Vol 9 (1) ◽  
Author(s):  
Marius Ciprian Rusu ◽  
Ionut Cameliu Ichim ◽  
Marcel Popa ◽  
Daniela Rusu ◽  
Mihai Rusu
Keyword(s):  
Thermal Stability ◽  
Compressive Strength ◽  
Glass Transition ◽  
Thermal Properties ◽  
Transition Temperature ◽  
Bone Cement ◽  
Setting Time ◽  
Maximum Temperature ◽  
Acrylic Bone Cement ◽  
Compression Tests

AbstractBromine-containing methacrylate, 2-(2-bromoisobutyryloxy) ethyl methacrylate (BIEM), had been used in the formulation of acrylic radiopaque cements. The effect of this monomer incorporated into the liquid phase of acrylic bone cement (ABC), on the curing parameters, thermal properties, water absorption, density, compression tests and radiopacity was studied. A decrease of maximum temperature and an increase of the setting time were observed with the addition of the brominecontaining monomer in the radiolucent cement composition. Adding BIEM in radiolucent ABCs composition results in the decrease of glass transition temperature and increase in its thermal stability. The ABCs modified with bromine-containing comonomer are characterized by polymerization shrinkage lower than the radiolucent cement. Addition of bromine-containing comonomer in radiolucent ABC composition determines the increase of compressive strength. The ABCs modified with brominecontaining comonomer proved to be radiopaque.

scholarly journals Physicochemical Properties and Dentin Bond Strength of a Tricalcium Silicate-Based Retrograde Material

2017 ◽  
Vol 28 (1) ◽  
pp. 51-56 ◽  
Author(s):  
Camila de Paula Telles Pires Lucas ◽  
Raqueli Viapiana ◽  
Roberta Bosso-Martelo ◽  
Juliane Maria Guerreiro-Tanomaru ◽  
Josette Camilleri ◽  
...  
Keyword(s):  
Compressive Strength ◽  
Bond Strength ◽  
Physicochemical Properties ◽  
Setting Time ◽  
Tricalcium Silicate ◽  
Final Setting Time ◽  
Root Canal Dentin ◽  
Post Hoc ◽  
Push Out

Abstract The aim of this study was to evaluate the physicochemical properties and the apical dentin bond strength of the tricalcium silicate-based Biodentine in comparison to white MTA and zinc oxide eugenol-based cement (ZOE). Setting time and radiopacity were evaluated according to ISO 6876:2012 specification. Final setting time, compressive strength and pH were also assessed. Material’s bond strength to the apical root canal dentin was measured by the push-out assay. Data were analyzed by ANOVA and Tukey-Krammer post-hoc test. Biodentine presented the shortest initial (16.2±1.48 min) and final setting time (35.4±5.55 min). Radiopacity of Biodentine (2.79±0.27 mmAl) does not agree with ISO 6876:2012 specifications. On the other hand, Biodentine showed higher compressive strength after 21 days (37.22±5.27 MPa) and higher dentin bond strength (11.2±2.16 MPa) in comparison to white MTA (27.68±3.56 MPa for compressive strength and 2.98±0.64 MPa for bond strength) (p<0.05). Both MTA and Biodentine produced an alkaline environment (approximately pH 10) (p>0.05) compared to ZOE (pH 7). It may be concluded that Biodentine exhibited faster setting, higher long-term compressive strength and bond strength to the apical dentin than MTA and ZOE.

Sign in / Sign up

Export Citation Format

Share Document