scholarly journals M232. COORDINATED SPECIALTY CARE FOR FIRST EPISODE PSYCHOSIS IN MINNESOTA

2020 ◽  
Vol 46 (Supplement_1) ◽  
pp. S225-S225
Author(s):  
Jamie Fischer ◽  
Joshua Mervis ◽  
Erin Begnel ◽  
Piper Meyer-Kalos
Keyword(s):  
Substance Use ◽  
Repeated Measures ◽  
Integrated Treatment ◽  
Self Report ◽  
First Episode ◽  
Future Research ◽  
Illness Management ◽  
Global Functioning ◽  
Significant Difference ◽  
Over Time

Abstract Background People who are experiencing a First Episode of Psychosis (FEP) often have limited recovery from non-integrated treatment approaches in usual settings. Treatment of FEP typically entails high rates of non-adherence, disengaging from treatment, and increased rates of relapse (Mueser et al., 2015; Kane et al., 2016). NAVIGATE is an evidence-based approach implemented in the Recovery After an Initial Schizophrenia Episode treatment project. Methods The present study is a review of archival data with NAVIGATE model teams in Minnesota. Clinical information from 118 people with FEP was reviewed from the first 6-months of treatment, with a subset analyzed for the first 12-months. Individuals were assessed with clinician ratings of current needs, illness management, and global functioning. Self-report assessments addressed symptoms and illness management from the client’s perspective. Data was analyzed using repeated measures analysis of variance with post-hoc honest significant difference testing. Additional data analysis utilized McNemar’s test, a repeated measures test using counts and a chi-square distribution. Results Total current needs did not change significantly across time. All other domains assessed showed significant differences between intake and 6-months. All other domains except total needs showed significant differences between intake and 12-months. No domains showed significant differences between 6-months and 12-months. Substance use was not reduced over time. Antipsychotic medication use was not reduced over time. Hospitalizations were substantially reduced from intake to 6-months. Discussion Almost all symptoms improved from intake to 6-months. No additional treatment gains were observed from 6-months to 12-months. Improvements from intake were stable from 6-months to 12-months. Most symptoms improved from intake to 6-months but not beyond. The NAVIGATE model was a successful intervention as implemented in Minnesota. Overall, symptom reduction gains were durable at 12-months, hospitalizations were reduced from intake to 6-months, but the intervention did not improve substance use. Substance use, continued improvement of symptoms beyond the 6-month mark, and further improvements in symptoms or reduced hospitalizations are areas for future research and treatment development.

scholarly journals Counting Bees: Learning Outcomes from Participation in the Dutch National Bee Survey

2021 ◽  
Vol 13 (9) ◽  
pp. 4703
Author(s):  
Wessel Ganzevoort ◽  
Riyan J. G. van den Born
Keyword(s):  
Learning Outcomes ◽  
Citizen Science ◽  
Repeated Measures ◽  
Self Report ◽  
Survey Study ◽  
Future Research ◽  
Wild Bees ◽  
Significant Difference ◽  
Citizen Science Project ◽  
The Impact

Citizen science approaches to data collection are growing in popularity, in part because of their potential for achieving both scientific and educational objectives. Evaluating the impacts of participation on citizen scientists is important, yet such evaluations are still relatively rare. In addition, recent literature reviews indicate that existing studies often focus on content learning, make limited use of existing scales, and rarely report null results. This paper reports an evaluation of the demographic profile, motivations and learning outcomes of participants in the Dutch National Bee Survey, a national-scale citizen science project involving citizens in collecting observational data of wild bees. Using a repeated measures survey study, we assessed the impact of participation on respondents’ attitudes and behavioural intentions regarding bees, and their attitudes towards nature, citizenship, and citizen science. Our baseline (N = 373) and follow-up (N = 208) surveys indicate that our respondents are of a relatively high age and education level, have a pre-existing affinity with nature, and are strongly motivated by conservation concerns and learning about bees. Assessment of learning outcomes indicated a significant difference between two types of self-report questions: respondents reported significant gains in knowledge and appreciation of wild bees, yet attitudinal scales indicated no significant shifts in attitudes towards bees, nature, citizen science, or citizenship. In our discussion, we suggest several explanations for this finding, including respondents’ pre-existing affinity with nature, and advance suggestions for future research into citizen science learning outcomes.

scholarly journals Acute Comparative Effect of Foam Rolling and Static Stretching on Range of Motion in Rowers

2021 ◽  
Vol 13 (7) ◽  
pp. 3631
Author(s):  
Alfonso Penichet-Tomas ◽  
Basilio Pueo ◽  
Marta Abad-Lopez ◽  
Jose M. Jimenez-Olmedo
Keyword(s):  
Range Of Motion ◽  
Repeated Measures ◽  
Static Stretching ◽  
Foam Rolling ◽  
Significant Difference ◽  
Post Test ◽  
Alternating Treatment Design ◽  
Stroke Amplitude ◽  
Treatment Design ◽  
Over Time

Rowers’ anthropometric characteristics and flexibility are fundamental to increase stroke amplitude and optimize power transfer. The aim of the present study was to analyze the effect of foam rolling and static stretching on the range of motion over time. Eight university rowers (24.8 ± 3.4 yrs., height 182.3 ± 6.5 cm, body mass 79.3 ± 4.6 kg) participated in an alternating treatment design study with two-way repeated measures ANOVA. The sit and reach test was used to measure the range of motion. Both in the foam rolling and in the static stretching method, a pre-test (T0), a post-test (T1), and a post-15-min test (T2) were performed. A significant effect was observed on the range of motion over time (p < 0.001), but not for time x method interaction (p = 0.680). Significant differences were found between T0 and T1 with foam rolling and static stretching (p < 0.001, d = 0.4); p < 0.001, d = 0.6). The differences between T0 and T2 were also significant with both methods (p = 0.001, d = 0.4; p < 0.001, d = 0.4). However, no significant difference was observed between T1 and T2 (p = 1.000, d = 0.1; p = 0.089, d = 0.2). Foam roller and static stretching seem to be effective methods to improve the range of motion but there seems to be no differences between them.

scholarly journals Mood and Global Symptom Changes among Psychotherapy Clients with Depressive Personality

2012 ◽  
Vol 2012 ◽  
pp. 1-12
Author(s):  
Rachel E. Maddux ◽  
Lars-Gunnar Lundh
Keyword(s):  
Repeated Measures ◽  
Mixed Model ◽  
Psychological Symptoms ◽  
Self Report ◽  
Treatment Results ◽  
Repeated Measures Analysis ◽  
Depressive Personality ◽  
Symptom Changes ◽  
Psychotherapy Clients ◽  
Over Time

The present study assessed the rate of depressive personality (DP), as measured by the self-report instrument depressive personality disorder inventory (DPDI), among 159 clients entering psychotherapy at an outpatient university clinic. The presenting clinical profile was evaluated for those with and without DP, including levels of depressed mood, other psychological symptoms, and global severity of psychopathology. Clients were followed naturalistically over the course of therapy, up to 40 weeks, and reassessed on these variables again after treatment. Results indicated that 44 percent of the sample qualified for DP prior to treatment, and these individuals had a comparatively more severe and complex presenting disposition than those without DP. Mixed-model repeated-measures analysis of variance was used to examine between-groups changes on mood and global severity over time, with those with DP demonstrating larger reductions on both outcome variables, although still showing more symptoms after treatment, than those without DP. Only eleven percent of the sample continued to endorse DP following treatment. These findings suggest that in routine clinical situations, psychotherapy may benefit individuals with DP.

083 Circadian Preference is Associated with Impulsivity at Both the Trait and State Level

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A35-A35
Author(s):  
Brant Hasler ◽  
Meredith Wallace ◽  
Jessica Graves ◽  
Sarah Pedersen
Keyword(s):  
Substance Use ◽  
White Women ◽  
Multilevel Models ◽  
State Level ◽  
Self Report ◽  
Future Research ◽  
Sleep Timing ◽  
Composite Scale ◽  
Primary Sample ◽  
Circadian Preference

Abstract Introduction Impulsivity is a multifaceted construct with well-documented risk for substance use problems. A circadian preference towards eveningness has been linked to trait, global impulsivity. Here we extend existing literature by investigating whether eveningness is associated with multiple facets of impulsivity at both trait- and state-level impulsivity. We also examined these associations utilizing daily measures of sleep timing and duration. Methods The primary sample included 78 moderate-to-heavy social drinkers (aged 21–35, 100% White men) with circadian preference data (Composite Scale of Morningness: CSM). Five facets of impulsivity were assessed via the UPPS-P, both at baseline (full scale) and up to 6 times per day over 10 days (reduced scale). Daily sleep timing (midsleep) and duration were assessed via self-report over 10 days. Multilevel models were used to examine between- and within-person associations, accounting for covariates and correcting for multiple comparisons. Results Between-person models found that eveningness was associated with multiple facets of impulsivity, at trait (lack of perseverance) and state levels (negative urgency, positive urgency, lack of perseverance, and lack of premeditation). However, average midsleep and duration were generally unrelated to impulsivity when accounting for circadian preference. Within-person models in the primary sample largely paralleled the between-person findings. In a larger, more diverse sample (29.1% self-identified as Black, 29.7% female) without CSM data, later midsleep timing was associated with greater mean state-level impulsivity across multiple facets. These effects largely appear to be driven by White women. Conclusion A circadian preference for eveningness is strongly associated with multiple facets of impulsivity, at both trait- and state-levels, potentially increasing risk for substance use. This association does not appear to be driven by actual daily sleep timing and/or duration. Future research with objective measures of sleep in larger, more diverse samples will be important to clarify implications for sleep-focused prevention and/or treatment of substance use. Support (if any) Supported by grants from NIH (R01AA026249; K01 AA021135), as well as a Foundation Grant from ABMRF/The Foundation for Alcohol Research.

scholarly journals Temporal Considerations for Self-Report Research Using Short Message Service

2016 ◽  
Vol 28 (4) ◽  
pp. 200-206 ◽  
Author(s):  
Erin Walsh ◽  
Jay K. Brinker
Keyword(s):  
Repeated Measures ◽  
Short Message Service ◽  
Response Rate ◽  
Time Of Day ◽  
High Response Rate ◽  
Self Report ◽  
Short Message ◽  
Significant Difference ◽  
Message Service ◽  
Working Day

Abstract. When using Short Message Service (SMS) as a tool for data collection in psychological research, participants can be contacted at any time. This study examined how sampling frequency and time of day of contact impacted on response rates, response completeness, and response delay in repeated measures data collected via SMS. Eighty-five undergraduate students completed a six-item self-report questionnaire via SMS, in response to 20 SMS prompts sent on a random schedule. One group responded across 2 days, the other on a compressed schedule of 1 day. Overall, there was a high response rate. There was no significant difference in response rate, completeness, and delay of those responding across 1 or 2 days. Timing between prompts did not impact on response behavior. Responses were more likely to be complete if prompts were sent during the working day. The shortest time between prompts was 15 min, however, and use of an undergraduate sample limits generalizability. When conducting repeated measures sampling using SMS, researchers should be aware that more frequent sampling can be associated with poorer data quality, and should aim to collect data during the working day rather than mornings or evenings.

scholarly journals An Acute Comparison of the Change of Serum Lipids, Glucose, and hs-CRP levels After Consumption of a Beef Burger Versus a Vegetarian Burger in Healthy Adults

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 136-136
Author(s):  
Tania Simone Barros ◽  
Maple Schompoopong ◽  
Shih-Ying Wu ◽  
Cindy Kosch ◽  
Gurinder Bains ◽  
...  
Keyword(s):  
Fast Food ◽  
Healthy Adults ◽  
Future Research ◽  
Initial Increase ◽  
Blood Biomarkers ◽  
Glucose Levels ◽  
Significant Difference ◽  
Beef Burger ◽  
Hs Crp ◽  
Over Time

Abstract Objectives A strong positive association exists between the consumption of fast food and risk of chronic diseases, such as heart disease and type 2 diabetes. Some individuals seek more healthful food alternatives, which include vegetarian products. The fast food industry is investing in more plant-based products. The objective of this study is to compare the change in blood biomarkers (lipids, glucose and high sensitivity C-reactive protein (hs-CRP) levels) after consumption of a beef burger versus a vegetarian burger. Methods Thirty-five healthy adults (22 females, 13 males), with mean age 28.5 ± 6.1 and mean Body Mass Index 24.4 kg/m² ± 3.5 completed a double blind, randomized, crossover study. After an eight-hour fast, they were randomly assigned to eat either a beef or vegetarian (Impossible) burger. One week later, the burgers were switched. The biomarkers were measured while fasting, and at 30, 60, and 120 min post-burger consumption. Results Linear mixed model was used for data fitting to assess the effect of adjusted covariates on selected nutrients. Blood triglyceride levels significantly increased from baseline over time after consumption of each type of burger (p ˂ 0.001). Consumption of the vegetarian burger showed significantly faster increase in triglycerides compared to the beef burger (p ˂ 0.001). At 120 min, there was no significant difference in the levels. Low-density lipoproteins significantly decreased over time following both types of burgers (p ˂ 0.001). There was no significant difference between the two burgers. Glucose levels showed significant changes over time for both groups (p ˂ 0.001). There was a significantly (p ˂ 0.004) greater change (initial increase, then decrease) in glucose levels after the vegetarian compared to the beef burger. Glucose levels peaked at 30 min, returning to baseline at 120 min for both groups. There was no significant difference in total cholesterol (p = 0.62), high-density lipoprotein (p = 0.81), or hs-CRP (p = 0.58) within or between groups. Conclusions Contrary to popular thought, consumption of beef and vegetarian burgers produces similar changes in acute blood biomarkers. Future research is warranted. Funding Sources This study was supported by Loma Linda University.

scholarly journals Sexting and Substance Use among Women Arrested for Domestic Violence: A Brief Report

2020 ◽  
Vol 14 ◽  
pp. 117822182094633
Author(s):  
Autumn Rae Florimbio ◽  
Meagan J Brem ◽  
Hannah L Grigorian ◽  
Alisa R Garner ◽  
Gregory L Stuart
Keyword(s):  
Domestic Violence ◽  
Intimate Partner Violence ◽  
Substance Use ◽  
Drug Use ◽  
Partner Violence ◽  
Risky Behaviors ◽  
Intimate Partner ◽  
Self Report ◽  
Sexual Content ◽  
Significant Difference

Background: Advances in technology provide opportunities for communication using electronic mediums. Sexting is one form of electronic communication and includes the sending of explicit sexual content (e.g., photos, text) through electronic mediums. Previous research demonstrated a positive association between sexting and behaviors such as substance use. Moreover, substance use increases the risk for intimate partner violence and is also associated with risky behaviors. Objectives: The aim of the present study was to examine the prevalence of sexting in a sample of 84 women mandated to attend batterer intervention programs following arrest for domestic violence. The associations between sexting, substance use, and intimate partner violence were also examined. Method: Participants completed self-report questionnaires that assessed sexting, intimate partner violence, and alcohol and drug use symptoms. Results: Fifty-four percent of participants reported being asked to send a sext, 35.1% reported sending a sext, and 32.0% reported requesting a sext. Drug use symptoms were positively associated with some forms of sexting and intimate partner violence. There was a significant difference in drug use symptoms, such that women who received a request to send a sext had significantly more symptoms relative to women who had not received a request to send a sext. Conclusion: This is the first examination of sexting in a sample of women arrested for domestic violence. Findings indicate an association between drug use symptoms, sexting, and intimate partner violence, warranting continued research in this domain.

scholarly journals T189. FREE THYROXIN CONCENTRATIONS MODERATE THE RESPONSE TO A COGNITIVE REMEDIATION THERAPY IN PEOPLE WITH EARLY PSYCHOSIS: PRELIMINARY FINDINGS

2020 ◽  
Vol 46 (Supplement_1) ◽  
pp. S303-S304
Author(s):  
Francesc Estrada ◽  
Josep Maria Crosas ◽  
Maribel Ahuir ◽  
Sara Pérez ◽  
Wanda Zabala ◽  
...  
Keyword(s):  
Repeated Measures ◽  
Cognitive Remediation ◽  
Early Psychosis ◽  
Cognitive Tasks ◽  
First Episode ◽  
Cognitive Changes ◽  
Cognitive Domains ◽  
Episode Psychosis ◽  
Changes Over Time ◽  
Over Time

Abstract Background Cognitive deficits are a common cause of functional disability in people with psychotic disorders. Cognitive remediation produces moderate improvements in cognitive performance in people with schizophrenia, although there is variability in the responses between patients. As previous longitudinal studies suggest that free thyroxin (FT4) levels influence attention cognitive tasks in patients with early psychosis, we aimed to conduct a pilot study to explore whether thyroid hormones might predict the response to cognitive remediation therapy (CRT) in patients with first-episode psychosis. Methods 27 patients (8 women; 19 men) with first-episode psychosis aged between 18 and 35 years old were randomized to receive a computerized CRT for three months (2 sessions/week) (N=14) or treatment as usual (TAU) (N=13). A full cognitive battery (CANTAB Schizophrenia) was administered at baseline and follow-up (3 months later, after the CRT/TAU period). Plasma levels of thyroid-stimulating hormone (TSH) and FT4 were measured. Data were analyzed on an intention-to-treat basis. Correlation analyses were conducted to explore the association between TSH and FT4 levels and cognitive changes over time. An ANOVA for repeated measures was used to compare longitudinal changes over time by the experimental group while adjusting for TSH and FT4 levels. Significance was defined as p&lt;0.05. Results TSH concentrations were not associated with cognitive changes over time. FT4 concentrations were associated with cognitive worsening over time in cognitive tasks dealing with reaction time (simple median movement time [r= 0.60, p= 0.003]; simple median reaction time [r= 0.44, p= 0.039]), sustained attention (signal detection for the rapid visual processing task [r= -0.46, p= 0.028]) and verbal memory (immediate recognition [r= -0.54, p= 0.008]; delayed recognition [r= -0.48, p= 0.019]). The ANOVA for repeated measures did not show time by group effects although a time by FT4 significant effect was found for cognitive tasks dealing with these cognitive domains (p&lt;0.05 for all). Discussion Although a direct effect of the CRT on cognitive improvement was not found, baseline FT4 concentrations appeared to predict the response to CRT in people with early psychosis. Significant associations were found for cognitive domains dealing with attention processes, which are in accordance with previous studies exploring the association between thyroid function and cognitive functioning in early psychotic patients. Our preliminary findings suggest that the determination of thyroid function status might be important for establishing which patients could show cognitive improvements over time. If these results are replicated in larger studies, the determination of thyroid status might help identify those individuals more prone for showing cognitive improvements, and allowing the implementation of a personalized medicine approach in the field of cognitive rehabilitation in psychosis.

scholarly journals When Research Meets Reality–-Lessons Learned from a Pragmatic Multisite Group-Randomized Clinical Trial on Psychosocial Interventions in the Psychiatric and Addiction Field

2012 ◽  
Vol 6 ◽  
pp. SART.S9245 ◽  
Author(s):  
Linda E. Wüsthoff ◽  
Helge Waal ◽  
Rolf W. Gråwe
Keyword(s):  
Clinical Trial ◽  
Substance Use ◽  
Randomized Clinical Trial ◽  
Substance Use Disorders ◽  
Clinical Studies ◽  
Psychosocial Interventions ◽  
Integrated Treatment ◽  
Lessons Learned ◽  
Future Research ◽  
New Challenges

Research on treatments for patients with co-occurring psychiatric and substance use disorders is of core importance and at the same time highly challenging as it includes patients that are normally excluded from clinical studies. Such research may require methodological adaptations which in turn create new challenges. However, the challenges that arise in such studies are insufficiently discussed in the literature. The aim of this methodology paper is, firstly, to discuss the methodological adaptations that may be required in such research; secondly, to describe how such adaptations created new challenges in a group-randomized clinical trial on Integrated Treatment amongst patients with co-occurring psychiatric and substance use disorders. We also discuss how these challenges might be understood and highlight lessons for future research in this field. Trial registration: NCT00447733.

scholarly journals Change in Estradiol and Follicle-Stimulating Hormone across the Early Menopausal Transition: Effects of Ethnicity and Age

2004 ◽  
Vol 89 (4) ◽  
pp. 1555-1561 ◽  
Author(s):  
John F. Randolph ◽  
MaryFran Sowers ◽  
Irina V. Bondarenko ◽  
Siobán D. Harlow ◽  
Judith L. Luborsky ◽  
...  
Keyword(s):  
African American ◽  
African American Women ◽  
Ethnic Differences ◽  
Repeated Measures ◽  
Menopausal Status ◽  
Midlife Women ◽  
Self Report ◽  
Race Ethnicity ◽  
Caucasian Women ◽  
Over Time

Abstract Serum reproductive hormone concentrations were measured longitudinally in a community-based, multiethnic population of midlife women to assess whether ethnic differences exist in the patterns of change in estradiol (E2) and FSH and, if so, whether these differences are explained by host characteristics. We studied 3257 participants from seven clinical sites in the Study of Women’s Health Across the Nation (SWAN) who were aged 42–52 yr at baseline and self-identified as African American (28.2%), Caucasian (47.1%), Chinese (7.7%), Hispanic (8.4%), or Japanese (8.6%). E2 and FSH were assayed in serum collected primarily in the early follicular phase of a spontaneous menstrual cycle in three consecutive annual visits. The primary explanatory variables included in repeated-measures regression analyses were race/ethnicity, menopausal status, age, body mass index (BMI), day of the cycle, smoking, parity, socioeconomic status, study site, and the self-report of diabetes at baseline. At the baseline visit, 46.2% of the women were classified as being early perimenopausal, with the remaining being premenopausal. By the second follow-up visit, 5.5% of the women in that cohort were postmenopausal, 66.8% were early perimenopausal, 8.3% were late perimenopausal, and 19.4% remained premenopausal. Serum E2 concentrations decreased significantly with age, with a steeper decline at higher ages. FSH concentrations increased significantly with age, with a steeper increase at higher ages. Similar patterns in the decline of E2 and the increase in FSH with age were found across ethnic groups, but the levels of these hormones differed by race/ethnicity. Specifically, over time, Chinese and Japanese women had lower E2 concentrations but similar FSH levels, compared with Caucasian women, and African American women had higher FSH concentrations but comparable E2 levels with those of Caucasian women. These ethnic differences in E2 and FSH were independent of menopausal status. The effect of BMI on serum E2 and FSH levels varied by menopausal status. Increasing BMI was associated with decreasing concentrations of E2 among premenopausal and early perimenopausal women but was associated with increasing concentrations of E2 among late perimenopausal and postmenopausal women. Increasing BMI was associated with decreasing concentrations of FSH, with the effect of BMI becoming larger as women transitioned through menopause. We conclude that serum E2 levels decrease and FSH concentrations increase with increasing age in midlife women, that ethnic differences in E2 over time differ from ethnic differences in FSH and suggest ethnic differences in the pituitary-ovarian relationship, and that the effect of BMI on E2 and FSH concentrations varies by menopausal status.

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