scholarly journals Surface properties and bioactivity of TiO 2 nanotube array prepared by two-step anodic oxidation for biomedical applications

2019 ◽  
Vol 6 (4) ◽  
pp. 181948 ◽  
Author(s):  
Zhaoxiang Peng ◽  
Jiahua Ni
Keyword(s):  
Cell Adhesion ◽  
Electron Microscope ◽  
Impedance Spectroscopy ◽  
Surface Energy ◽  
Anodic Oxidation ◽  
Biomedical Applications ◽  
Nanotube Array ◽  
Measuring Device ◽  
X Ray ◽  
Cell Adhesion And Proliferation

A highly ordered TiO 2 nanotube array has been prepared on a commercial pure titanium substrate in a hydrofluoric (HF) electrolyte using a DC power source through two-step anodic oxidation. The morphology, composition, wettability and surface energy of the nanotube array have been characterized by using a field-emission scanning electron microscope (FE-SEM), a transmission electron microscope (JEM-2010) with energy-dispersive X-ray spectrometer EDX (INCA OXFORD), X-ray diffraction method, an atomic force microscope (AFM), an optical contact angle measuring device and the Owens method with two liquids. The electrochemical behaviours of anodic oxidation films with different structures have been investigated in Sodium Lactate Ringer's Injection at 37±1°C by potentiodynamic polarization curve and electrochemical impedance spectroscopy. The formation mechanism of the nanotube array and the advantages of two-step oxidation have been discussed according to the experimental observation and the characterized results. Meanwhile, the structural changes of nanotubes are analysed according to the results of impedance spectroscopy. Cytotoxicity testing and cell adhesion and proliferation have been studied in order to evaluate the bioactivity of the nanotube array film. The diameters of nanotubes are in the range of 120–140 nm. The nanotube surface shows better wettability and higher surface energy compared to the bare substrate. The nanotube surface exhibits a wide passivation range and good corrosion resistance. The growth of the nanotube array is the result of the combined action of the anodization and field-assisted dissolution. The nanotube array by two-step oxidation becomes more regular and orderly. Moreover, the nanotube array surface is non-toxic and favourable to cell adhesion and proliferation. Such nanotube array films are expected to have significant biomedical applications.

scholarly journals Surface Modification of the Alloy Ti-7.5Mo by Anodization for Biomedical Applications

2016 ◽  
Vol 869 ◽  
pp. 913-917 ◽  
Author(s):  
Ana Lucia do Amaral Escada ◽  
Javier Andres Muñoz Chaves ◽  
Ana Paula Rosifini Alves Claro
Keyword(s):  
Contact Angle ◽  
Electron Microscope ◽  
Biomedical Applications ◽  
Anatase Phase ◽  
Ammonium Fluoride ◽  
X Ray ◽  
Angle Measurements ◽  
Contact Angle Measurements ◽  
Simple Surface ◽  
Scanning Electron

The purpose of this study was to evaluate the TiO2 nanotubes growth and the variation in its diameter to improve the surface properties of Ti-7.5Mo to use for biomedical applications. For the nanotubes TiO2 growth, the samples were anodized in glycerol and ammonium fluoride and divided according to the anodizing potential at 5V to 10V and 24 hour time. The surfaces were examined by scanning electron microscope (SEM), X-ray analysis (XRD) and contact angle measurements. The average tube diameter, ranging in size from 13 to 23 nm, was found to increase with increasing anodizing voltage. It was also observed a decrease in contact angle in accordance with the increase in the anodizing potential. The X-ray analysis showed the presence of anatase phase in samples whose potential was 10V and this condition represents a simple surface treatment for Ti-7.5Mo alloy that has high potential for biomedical applications.

Influence of Acidity in Wet-Chemical Synthesis on the Joint of Nano-Sized β-Tricalcium Phosphate Particles with Collagen Fibrils in Their Composites

2006 ◽  
Vol 309-311 ◽  
pp. 585-588
Author(s):  
Chao Zou ◽  
Wen Jian Weng ◽  
Xu Liang Deng ◽  
Kui Cheng ◽  
Xin Zhi Wang ◽  
...  
Keyword(s):  
Electron Microscope ◽  
Tricalcium Phosphate ◽  
Biomedical Applications ◽  
Particle Dispersion ◽  
Collagen Fibrils ◽  
X Ray ◽  
Wet Chemical Synthesis ◽  
Wet Chemical ◽  
Collagen Suspension ◽  
Scanning Electron

β-tricalcium phosphate (β-TCP)/collagen composites are in the limelight for their biomedical applications. It is believed that joint status of β-TCP particles with collagen fibrils plays key roles in both osteoconductivity and biodegradability of composites. In this work, the influence of acidity during synthesis on the joint status between nano-sized β-TCP particles and collagen fibrils is investigated. The composites are characterized by X-ray diffractometer and Field Emission Scanning Electron Microscope. The results show that the joint status of nano-sized β-TCP particles with collagen fibrils in the composites depends on the acidity in collagen suspensions. A desired joint status with obvious disassembled collagen fibril, good particle dispersion and strong boding between the particles and the fibrils could be obtained when acidity of the collagen suspension is pH 2.

scholarly journals ANALISIS PENGARUH LAJU PUTAR TERHADAP KOROSI BAJA KARBON API 5LX65 MENGGUNAKAN METODE ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY

2012 ◽  
Vol 2 (1) ◽  
pp. 1
Author(s):  
Agus Solehudin ◽  
Asep Lukman
Keyword(s):  
Electron Microscope ◽  
Electrochemical Impedance Spectroscopy ◽  
Impedance Spectroscopy ◽  
Scanning Electron Microscope ◽  
Energy Dispersive Spectroscopy ◽  
Electrochemical Impedance ◽  
Energy Dispersive ◽  
X Ray ◽  
Scanning Electron

Pada percobaan ini, telah dipelajari pengaruh laju putar terhadap laju korosi baja karbon API 5LX65 yang direndam selama 24 jam dalam larutan NaCl 3,5% + 500 mg/L H2S menggunakan metode EIS (Electrochemical Impedance Spectroscopy) pada suhu 50oC dan pH 4 dengan variasi laju putar 50 rpm, 150 rpm, dan 250 rpm. Hasil percobaan memperlihatkan pergeseran dan penyempitan kurva setengah lingkaran impedansi imaginer terhadap impedansi real, dengan meningkatnya laju putar dari 50 rpm sampai dengan 250 rpm. Hal ini mengindikasikan bahwa aktifitas pelarutan baja meningkat dengan percepatan laju putar. Nilai Cdl meningkat dengan meningkatnya laju putar. Nilai tahanan polarisasi (Rp) semakin menurun dengan meningkatnya laju putar, sementara nilai tahanan larutan (Rs) relatif tidak berubah. Potensial korosi pada laju putar 50 rpm, 150 rpm dan 250 rpm stabil  pada -517 mV hingga -508 mV terhadap Ag/AgCl. Gabungan pengamatan Scanning Electron Microscope (SEM), Energy Dispersive Spectroscopy (EDS) dan X-Ray Diffractomer (XRD) menunjukkan terbentuknya lapisan produk korosi. Hasil analisis XRD spesimen uji yang dikorosikan pada suhu 50oC selama 24 jam menunjukkan bahwa lapisan produk korosi mengandung besi sulfida (FeS). Morfologi permukaan spesimen ini memperlihatkan adanya korosi sumuran.Kata kunci: laju putar, korosi, baja karbon, EIS, H2S

Anodic oxidation of graphite in H2SO4 dilatometry — in situ X-ray diffraction — Impedance spectroscopy

1983 ◽  
Vol 7 (3-4) ◽  
pp. 185-192 ◽  
Author(s):  
J.O. Besenhard ◽  
E. Wudy ◽  
H. Möhwald ◽  
J.J. Nickl ◽  
W. Biberacher ◽  
...  
Keyword(s):  
Impedance Spectroscopy ◽  
Anodic Oxidation ◽  
X Ray Diffraction ◽  
X Ray

scholarly journals Production of Biodegradable Palm Oil-Based Polyurethane as Potential Biomaterial for Biomedical Applications

Polymers ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 1842
Author(s):  
Fang Hoong Yeoh ◽  
Choy Sin Lee ◽  
Yew Beng Kang ◽  
Shew Fung Wong ◽  
Sit Foon Cheng ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Palm Oil ◽  
Biomedical Applications ◽  
Enzymatic Degradation ◽  
Cytotoxicity Test ◽  
Adhesion Test ◽  
Polyester Polyol ◽  
Isocyanate Index ◽  
Soft Tissue Engineering ◽  
Cell Adhesion And Proliferation

Being biodegradable and biocompatible are crucial characteristics for biomaterial used for medical and biomedical applications. Vegetable oil-based polyols are known to contribute both the biodegradability and biocompatibility of polyurethanes; however, petrochemical-based polyols were often incorporated to improve the thermal and mechanical properties of polyurethane. In this work, palm oil-based polyester polyol (PPP) derived from epoxidized palm olein and glutaric acid was reacted with isophorone diisocyanate to produce an aliphatic polyurethane, without the incorporation of any commercial petrochemical-based polyol. The effects of water content and isocyanate index were investigated. The polyurethanes produced consisted of > 90% porosity with interconnected micropores and macropores (37–1700 µm) and PU 1.0 possessed tensile strength and compression stress of 111 kPa and 64 kPa. The polyurethanes with comparable thermal stability, yet susceptible to enzymatic degradation with 7–59% of mass loss after 4 weeks of treatment. The polyurethanes demonstrated superior water uptake (up to 450%) and did not induce significant changes in pH of the medium. The chemical changes of the polyurethanes after enzymatic degradation were evaluated by FTIR and TGA analyses. The polyurethanes showed cell viability of 53.43% and 80.37% after 1 and 10 day(s) of cytotoxicity test; and cell adhesion and proliferation in cell adhesion test. The polyurethanes produced demonstrated its potential as biomaterial for soft tissue engineering applications.

scholarly journals Anodic Fabrication of Ti-Nb-Zr-O Nanotube Arrays

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Qiang Liu ◽  
Dongyan Ding ◽  
Congqin Ning
Keyword(s):  
Electron Microscope ◽  
Scanning Electron Microscope ◽  
Anodic Oxidation ◽  
Xrd Analysis ◽  
Lattice Parameter ◽  
Nanotube Arrays ◽  
X Ray ◽  
Diffraction Peaks ◽  
Scanning Electron ◽  
Zr Alloy

Highly ordered Ti-Nb-Zr-O nanotube arrays were fabricated through pulse anodic oxidation of Ti-Nb-Zr alloy in 1 M NaH2PO4containing 0.5 wt% HF electrolytes. The effect of anodization parameters and Zr content on the microstructure and composition of Ti-Nb-Zr-O nanotubes was investigated using a scanning electron microscope equipped with energy dispersive X-ray analysis. It was found that length of the Ti-Nb-Zr-O nanotubes increased with increase of Zr contents. The diameter and the length of Ti-Nb-Zr-O nanotubes could be controlled by pulse voltage. XRD analysis of Ti-Nb-Zr-O samples annealed at 500°C in air indicated that the (101) diffraction peaks shifted from 25.78° to 25.05° for annealed Ti-Nb-Zr-O samples with different Zr contents because of larger lattice parameter of Ti-Nb-Zr-O compared to that of undoped TiO2.

scholarly journals Fabrication of Pamidronic Acid-Immobilized TiO2/Hydroxyapatite Composite Nanofiber Mats for Biomedical Applications

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Yong-Suk Shin ◽  
Jyoti S. Borah ◽  
Adnan Haider ◽  
Sukyoung Kim ◽  
Man-Woo Huh ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Pamidronic Acid ◽  
Bone Scaffold ◽  
Electrospinning Technique ◽  
Bone Implant ◽  
X Ray ◽  
Hydroxyapatite Composite ◽  
Composite Nanofiber ◽  
Nanofiber Mats ◽  
Cell Adhesion And Proliferation

TiO2/hydroxyapatite (TiO2/HA) composite nanofiber mats were fabricated using an electrospinning technique. Subsequently, pamidronic acid (PDA) was immobilized on the surface of the TiO2/HA nanofiber mat to improve osseointegration. X-ray photoelectron microscopy and scanning electron microscopy (SEM) were used to characterize the structure and morphology of the PDA-immobilized TiO2/HA composite nanofiber mat (TiO2/HA-P). The potential of TiO2/HA-P as a bone scaffold was assessed by examining the cell adhesion and proliferation of osteoblasts and osteoclasts. The adhesion and proliferation of osteoblasts on the TiO2/HA-P composite nanofiber mat were slightly higher than those on the TiO2/HA composite nanofiber mat, whereas the viability of osteoclasts on the TiO2/HA-P nanofiber mat was significantly suppressed. These results suggest that the TiO2/HA-P nanofiber mat has the potential for use as a therapeutic bone implant.

Laponite-based Nanomaterials for Biomedical Applications: A Review

2019 ◽  
Vol 25 (4) ◽  
pp. 424-443 ◽  
Author(s):  
Sabya S. Das ◽  
Neelam ◽  
Kashif Hussain ◽  
Sima Singh ◽  
Afzal Hussain ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Cell Adhesion ◽  
Targeted Drug Delivery ◽  
Biomedical Applications ◽  
Biodegradable Materials ◽  
Clay Material ◽  
Research Directions ◽  
Targeted Drug ◽  
Cell Adhesion And Proliferation

Laponite based nanomaterials (LBNMs) are highly diverse regarding their mechanical, chemical, and structural properties, coupled with shape, size, mass, biodegradability and biocompatibility. These ubiquitous properties of LBNMs make them appropriate materials for extensive applications. These have enormous potential for effective and targeted drug delivery comprised of numerous biodegradable materials which results in enhanced bioavailability. Moreover, the clay material has been explored in tissue engineering and bioimaging for the diagnosis and treatment of various diseases. The material has been profoundly explored for minimized toxicity of nanomedicines. The present review compiled relevant and informative data to focus on the interactions of laponite nanoparticles and application in drug delivery, tissue engineering, imaging, cell adhesion and proliferation, and in biosensors. Eventually, concise conclusions are drawn concerning biomedical applications and identification of new promising research directions.

X-ray microanalysis of thin specimens in the transmission electron microscope at voltages up to 1000 Kv.

1978 ◽  
Vol 36 (1) ◽  
pp. 540-541
Author(s):  
G. Cliff ◽  
M.J. Nasir ◽  
G.W. Lorimer ◽  
N. Ridley
Keyword(s):  
Electron Microscope ◽  
Transmission Electron Microscope ◽  
Weight Fraction ◽  
Present Series ◽  
Constant Independent ◽  
X Ray ◽  
Transmission Electron ◽  
Series Of Experiments ◽  
Image Position ◽  
X Ray Absorption

In a specimen which is transmission thin to 100 kV electrons - a sample in which X-ray absorption is so insignificant that it can be neglected and where fluorescence effects can generally be ignored (1,2) - a ratio of characteristic X-ray intensities, I1/I2 can be converted into a weight fraction ratio, C1/C2, using the equationwhere k12 is, at a given voltage, a constant independent of composition or thickness, k12 values can be determined experimentally from thin standards (3) or calculated (4,6). Both experimental and calculated k12 values have been obtained for K(11<Z>19),kα(Z>19) and some Lα radiation (3,6) at 100 kV. The object of the present series of experiments was to experimentally determine k12 values at voltages between 200 and 1000 kV and to compare these with calculated values.The experiments were carried out on an AEI-EM7 HVEM fitted with an energy dispersive X-ray detector.

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