On the Impact of Routing Algorithms in the Effectiveness of Queuing Schemes in High-Performance Interconnection Networks

2017 ◽  
Author(s):  
Jose Rocher-Gonzalez ◽  
Jesus Escudero-Sahuquillo ◽  
Pedro J. Garcia ◽  
Francisco J. Quiles
Keyword(s):  
Interconnection Networks ◽  
High Performance ◽  
Routing Algorithms ◽  
The Impact

Dietary Vitamin and Stability of Oral Anticoagulation: Proposal of a Diet with Constant Vitamin K1 Content

1997 ◽  
Vol 77 (03) ◽  
pp. 504-509 ◽  
Author(s):  
Sarah L Booth ◽  
Jacqueline M Charnley ◽  
James A Sadowski ◽  
Edward Saltzman ◽  
Edwin G Bovill ◽  
...  
Keyword(s):  
Dietary Intake ◽  
Vitamin K ◽  
High Performance ◽  
Case Reports ◽  
Food Composition ◽  
Dietary Guidelines ◽  
Dietary Vitamin ◽  
Vitamin K1 ◽  
The Stability ◽  
The Impact

SummaryCase reports cited in Medline or Biological Abstracts (1966-1996) were reviewed to evaluate the impact of vitamin K1 dietary intake on the stability of anticoagulant control in patients using coumarin derivatives. Reported nutrient-drug interactions cannot always be explained by the vitamin K1 content of the food items. However, metabolic data indicate that a consistent dietary intake of vitamin K is important to attain a daily equilibrium in vitamin K status. We report a diet that provides a stable intake of vitamin K1, equivalent to the current U.S. Recommended Dietary Allowance, using food composition data derived from high-performance liquid chromatography. Inconsistencies in the published literature indicate that prospective clinical studies should be undertaken to clarify the putative dietary vitamin K1-coumarin interaction. The dietary guidelines reported here may be used in such studies.

Efficient Instruction and Data Caching for High Performance Embedded Processors

1970 ◽  
pp. 9
Author(s):  
A. Ferrerón Labari ◽  
D. Suárez Gracia ◽  
V. Viñals Yúfera
Keyword(s):  
Embedded Systems ◽  
Power Consumption ◽  
Low Power ◽  
Interconnection Networks ◽  
High Performance ◽  
Critical Issue ◽  
Content Management ◽  
Structure Design ◽  
Portable Devices ◽  
On Chip

In the last years, embedded systems have evolved so that they offer capabilities we could only find before in high performance systems. Portable devices already have multiprocessors on-chip (such as PowerPC 476FP or ARM Cortex A9 MP), usually multi-threaded, and a powerful multi-level cache memory hierarchy on-chip. As most of these systems are battery-powered, the power consumption becomes a critical issue. Achieving high performance and low power consumption is a high complexity challenge where some proposals have been already made. Suarez et al. proposed a new cache hierarchy on-chip, the LP-NUCA (Low Power NUCA), which is able to reduce the access latency taking advantage of NUCA (Non-Uniform Cache Architectures) properties. The key points are decoupling the functionality, and utilizing three specialized networks on-chip. This structure has been proved to be efficient for data hierarchies, achieving a good performance and reducing the energy consumption. On the other hand, instruction caches have different requirements and characteristics than data caches, contradicting the low-power embedded systems requirements, especially in SMT (simultaneous multi-threading) environments. We want to study the benefits of utilizing small tiled caches for the instruction hierarchy, so we propose a new design, ID-LP-NUCAs. Thus, we need to re-evaluate completely our previous design in terms of structure design, interconnection networks (including topologies, flow control and routing), content management (with special interest in hardware/software content allocation policies), and structure sharing. In CMP environments (chip multiprocessors) with parallel workloads, coherence plays an important role, and must be taken into consideration.

Alpha Tocopherol Loaded in Liposome: Preparation, Optimization, Characterization and Sperm Motility Protection

2020 ◽  
Vol 10 (3) ◽  
pp. 228-236 ◽  
Author(s):  
Lamia Taouzinet ◽  
Sofiane Fatmi ◽  
Allaeddine Khellouf ◽  
Mohamed Skiba ◽  
Mokrane Iguer-ouada
Keyword(s):  
Vitamin E ◽  
Sperm Motility ◽  
High Performance ◽  
Positive Impact ◽  
Alpha Tocopherol ◽  
Ethanol Injection ◽  
Liposome Preparation ◽  
Liposome Size ◽  
Optimum Solution ◽  
The Impact

Background: Alpha-tocopherol is a potent antioxidant involved in sperm protection particularly during cryopreservation. However, its poor solubility limits the optimal protection in aqueous solutions. Objective: The aim of this study was to enhance the solubility of α-tocopherol by the use of liposomes. Methods: The experimental approach consisted to load vitamin E in liposomes prepared by ethanol injection method and the optimization carried out by an experimental design. The optimum solution was characterized by high performance liquid chromatography and scanning electron microscope. Finely, the impact on sperm motility protection was studied by the freezing technic of bovine sperm. Results: The optimum solution was obtained when using 10.9 mg/ml of phospholipids, 1.7 mg/ml of cholesterol and 2 mg/ml of vitamin E. The liposome size was 99.86 nm, providing 78.47% of loaded efficiency. The results showed also a significant positive impact on sperm motility after hours of preservation. Conclusion: In conclusion, the current results showed the interest of liposome preparation as an alternative to enhance vitamin E solubility and to protect spermatozoa during cryopreservation.

scholarly journals Technology Entrepreneurship and the Performance of Enterprises in the Conditions of Covid-19 Pandemic: The Fuzzy Set Analysis of Waste to Energy Enterprises in Poland

Energies ◽  
2021 ◽  
Vol 14 (13) ◽  
pp. 3891
Author(s):  
Piotr Kordel ◽  
Radosław Wolniak
Keyword(s):  
Fuzzy Set ◽  
High Performance ◽  
Qualitative Comparative Analysis ◽  
Flexible Structures ◽  
Implementation Strategies ◽  
Waste To Energy ◽  
Energy Industry ◽  
Technology Entrepreneurship ◽  
Research Results ◽  
The Impact

This article’s aim is to explain the impact of technology entrepreneurship phenomenon on waste management enterprise performance in the conditions of COVID-19 pandemic. The concept of technology entrepreneurship according to the configuration approach and the category of high-performance organization are the theoretical bases of empirical investigation. For the implementation of empirical research, Fuzzy set Qualitative Comparative Analysis (FsQCA) was adopted. The research sample included a group of producers of Refused Derived Fuel (RDF) as a central part of the waste to energy industry located in Poland. The research results showed that the waste to energy sector is highly immune to pandemic threats. While during COVID-19, the basic economic parameters (i.e., sales, profitability and employment) of the entire industry in Poland clearly decreased, the same parameters in the case of the waste to energy industry remained at the same level. The research results allow the formulation of two high-performance models of technology entrepreneurship in the waste to energy industry under COVID-19 conditions. The first model is based on traditional technologies and hierarchical organizational structures, and the second is using innovative technologies and flexible structures. Both technology entrepreneurship models are determined by their emergence as complementary to implementation strategies and the opportunity-oriented allocation of resources within business model portfolios.

scholarly journals Grill Workers Exposure to Polycyclic Aromatic Hydrocarbons: Levels and Excretion Profiles of the Urinary Biomarkers

2020 ◽  
Vol 18 (1) ◽  
pp. 230
Author(s):  
Marta Oliveira ◽  
Sílvia Capelas ◽  
Cristina Delerue-Matos ◽  
Simone Morais
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Aromatic Hydrocarbons ◽  
High Performance ◽  
Principal Component ◽  
Fold Increase ◽  
Urinary Biomarkers ◽  
Analysis Model ◽  
Exposed Workers ◽  
Polycyclic Aromatic ◽  
The Impact

Grilling activities release large amounts of hazardous pollutants, but information on restaurant grill workers’ exposure to polycyclic aromatic hydrocarbons (PAHs) is almost inexistent. This study assessed the impact of grilling emissions on total workers’ exposure to PAHs by evaluating the concentrations of six urinary biomarkers of exposure (OHPAHs): naphthalene, acenaphthene, fluorene, phenanthrene, pyrene, and benzo(a)pyrene. Individual levels and excretion profiles of urinary OHPAHs were determined during working and nonworking periods. Urinary OHPAHs were quantified by high-performance liquid-chromatography with fluorescence detection. Levels of total OHPAHs (∑OHPAHs) were significantly increased (about nine times; p ≤ 0.001) during working comparatively with nonworking days. Urinary 1-hydroxynaphthalene + 1-hydroxyacenapthene and 2-hydroxyfluorene presented the highest increments (ca. 23- and 6-fold increase, respectively), followed by 1-hydroxyphenanthrene (ca. 2.3 times) and 1-hydroxypyrene (ca. 1.8 times). Additionally, 1-hydroxypyrene levels were higher than the benchmark, 0.5 µmol/mol creatinine, in 5% of exposed workers. Moreover, 3-hydroxybenzo(a)pyrene, biomarker of exposure to carcinogenic PAHs, was detected in 13% of exposed workers. Individual excretion profiles showed a cumulative increase in ∑OHPAHs during consecutive working days. A principal component analysis model partially discriminated workers’ exposure during working and nonworking periods showing the impact of grilling activities. Urinary OHPAHs were increased in grill workers during working days.

scholarly journals Opportunistic Network Algorithms for Internet Traffic Offloading in Music Festival Scenarios

Sensors ◽  
2021 ◽  
Vol 21 (10) ◽  
pp. 3315
Author(s):  
Aida-Ștefania Manole ◽  
Radu-Ioan Ciobanu ◽  
Ciprian Dobre ◽  
Raluca Purnichescu-Purtan
Keyword(s):  
High Performance ◽  
Geographical Area ◽  
Mobility Model ◽  
Routing Algorithms ◽  
Message Delivery ◽  
Opportunistic Network ◽  
Key Factors ◽  
Network Algorithms ◽  
Music Festival ◽  
Social Metrics

Constant Internet connectivity has become a necessity in our lives. Hence, music festival organizers allocate part of their budget for temporary Wi-Fi equipment in order to sustain the high network traffic generated in such a small geographical area, but this naturally leads to high costs that need to be decreased. Thus, in this paper, we propose a solution that can help offload some of that traffic to an opportunistic network created with the attendees’ smartphones, therefore minimizing the costs of the temporary network infrastructure. Using a music festival-based mobility model that we propose and analyze, we introduce two routing algorithms which can enable end-to-end message delivery between participants. The key factors for high performance are social metrics and limiting the number of message copies at any given time. We show that the proposed solutions are able to offer high delivery rates and low delivery delays for various scenarios at a music festival.

scholarly journals Mycosporine-Like Amino Acids from Red Macroalgae: UV-Photoprotectors with Potential Cosmeceutical Applications

2021 ◽  
Vol 11 (11) ◽  
pp. 5112
Author(s):  
Julia Vega ◽  
Geniane Schneider ◽  
Bruna R. Moreira ◽  
Carolina Herrera ◽  
José Bonomi-Barufi ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Amino Acids ◽  
High Performance ◽  
Nitrogen Availability ◽  
Antioxidant Properties ◽  
Published Data ◽  
Diverse Group ◽  
Red Macroalgae ◽  
Thermo Stability ◽  
The Impact

Macroalgae belong to a diverse group of organisms that could be exploited for biomolecule application. Among the biocompounds found in this group, mycosporine-like amino acids (MAAs) are highlighted mainly due to their photoprotection, antioxidant properties, and high photo and thermo-stability, which are attractive characteristics for the development of cosmeceutical products. Therefore, here we revise published data about MAAs, including their biosynthesis, biomass production, extraction, characterization, identification, purification, and bioactivities. MAAs can be found in many algae species, but the highest concentrations are found in red macroalgae, mainly in the order Bangiales, as Porphyra spp. In addition to the species, the content of MAAs can vary depending on environmental factors, of which solar radiation and nitrogen availability are the most influential. MAAs can confer photoprotection due to their capacity to absorb ultraviolet radiation or reduce the impact of free radicals on cells, among other properties. To extract these compounds, different approaches can be used. The efficiency of these methods can be evaluated with characterization and identification using high performance liquid chromatography (HPLC), associated with other apparatus such as mass spectrometry (MS) and nuclear magnetic resonance (NMR). Therefore, the data presented in this review allow a broad comprehension of MAAs and show perspectives for their inclusion in cosmeceutical products.

Highly epoxidized soybean oil in replacement of mineral oil for high performance on silica-filled tread rubber compounds

2021 ◽  
pp. 009524432110290
Author(s):  
Leandro Hernán Esposito ◽  
Angel José Marzocca
Keyword(s):  
Soybean Oil ◽  
High Performance ◽  
Rolling Resistance ◽  
Wear Test ◽  
Mineral Oil ◽  
Epoxidized Soybean Oil ◽  
Styrene Butadiene Rubber ◽  
Butadiene Rubber ◽  
Rubber Compound ◽  
The Impact

The potential replacement of a treated residual aromatic extract mineral oil (TRAE) by a highly epoxidized soybean oil (ESO) into a silica-filled styrene-butadiene rubber compound was investigated. In order to determine if ESO compounds performance are suitable for tread tire applications, processing properties cure and characteristics were evaluated. The impact of ESO amount on the silica dispersion was confirmed by Payne Effect. The presence of chemical or physical interactions between ESO and silica improves the filler dispersion, enabling the compound processability and affecting the cure kinetic rate. An adjusted rubber compound with 2 phr of ESO and 2 phr of sulfur presented the higher stiffness and strength values with lower weight loss from a wear test compared with TRAE compound at an equal amount of oil and curing package. Furthermore, wet grip and rolling resistance predictors of both compounds gave comparable results, maintaining a better performance and reducing the dependence of mineral oil for tire tread compounds.

scholarly journals RADT-23. IMPACT OF REIRRADIATION UTILIZING STEREOTACTIC RADIOSURGERY ON RECURRENT GLIOBLASTOMA

2020 ◽  
Vol 22 (Supplement_2) ◽  
pp. ii186-ii186
Author(s):  
O’Dell Patrick ◽  
H Nickols ◽  
R LaRocca ◽  
K Sinicrope ◽  
D Sun ◽  
...  
Keyword(s):  
Stereotactic Radiosurgery ◽  
Median Survival ◽  
High Performance ◽  
Performance Status ◽  
Treatment Options ◽  
Methylation Status ◽  
Initial Therapy ◽  
Recurrent Glioblastoma ◽  
Control Group ◽  
The Impact

Abstract BACKGROUND Patients who have recurrent glioblastoma have limited treatment options. We conducted a retrospective review of patients with recurrent glioblastoma treated with standard initial radiation and temozolomide with tumor treating fields to investigate whether reirradiation using radiosurgery would be associated with improved outcomes. METHODS We reviewed the records of 54 consecutively treated patients with recurrent glioblastoma with ECOG 0 or 1 at recurrence and conducted Kaplan-Meier analysis with Log-rank testing to determine significance between groups. RESULTS We identified 24 patients who were treated without radiation therapy (control) while 30 patients underwent re-irradiation using radiosurgery (ReSRS) with a median total dose of 25Gy in five fractions. All patients had completed standard initial therapy, and there was no difference in the time to recurrence between the two groups (10 months for control, 15 months for ReSRS, [P = 0.17, HR for progression 0.65 (95% CI 0.38-1.13)]. A larger proportion of patients in the control arm (54%) had subtotal or gross total resection of the recurrence compared with the ReSRS group (44%, P < 0.05). The majority of patients had recurrence confirmed with biopsy (18/22 in control group, 25/31 in the ReSRS group). MGMT methylation status did not differ between control vs ReSRS (29% vs. 27%). ReSRS was associated with improved median survival from the time of first recurrence of 11.6 months versus 3.8 months in the control arm [P< 0.0001, HR for death 0.33 (95% CI 0.18-0.6)]. CONCLUSIONS In a group of patients with high performance status diagnosed with recurrent glioblastoma, reirradiation with stereotactic radiosurgery was associated with nearly one year median survival after recurrence. Additional analyses are warranted to determine the impact of concurrent systemic therapies with irradiation and underlying tumor or patient factors to predict outcomes.

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