Psychiatric symptoms may contribute to poor quality of life in adolescents with migraine

Abstract Aims Social isolation in people living with schizophrenia is associated with poor quality of life and increased symptom severity. Volunteer befriending interventions are a potential strategy for addressing social isolation, but evidence of their effectiveness is limited, particularly in low- and middle-income countries. We assessed the experiences of volunteer befriending and tested its effectiveness for improving the quality of life of patients with schizophrenia in Bosnia and Herzegovina. Methods Between March 2018 and July 2020, we conducted a parallel-group, randomised controlled trial in adults with schizophrenia and poor quality of life at an outpatient clinic in Sarajevo. Patients were randomised to either the intervention, in which they were matched with a volunteer befriender with whom they met fortnightly over the 6-month intervention period, or treatment as usual. The primary outcome was quality of life measured on the Manchester Short Assessment and secondary outcomes were psychiatric symptoms and objective social outcomes. Outcome measurement was conducted by blinded researchers at 6- and 12-months. Results In total, 65 patients were randomised into the intervention (n = 33) and control arms (n = 32) and 55 (85%) completed follow-up assessments at 6 months. Patients in the intervention showed a significantly more favourable quality of life at 6 months (primary outcome; mean difference: 0.7, 95% CI [0.3–1.1], p = 0.003) and 12 months (mean difference: 1.7, 95% CI [1.1–2.3], p < 0.001). They also had significantly lower symptom levels at both follow-ups, and a significantly more favourable objective social situation after 12 months. Participants reported largely positive experiences. Conclusion The exploratory trial conducted at one site found sustained improvements in quality of life and reductions in psychiatric symptoms. This suggests that volunteer befriending may be a feasible and effective treatment for patients with schizophrenia in resource-limited contexts, such as Bosnia and Herzegovina.

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SUN-423 Impact of Hyperthyroidism and Its Treatment on the Outcome of Mental Health, Occupational Functioning and Quality of Life - a Prospective Study

Journal of the Endocrine Society ◽

10.1210/jendso/bvaa046.1668 ◽

2020 ◽

Vol 4 (Supplement_1) ◽

Author(s):

Roopa Chopra ◽

Tejas Kumar Kalaria ◽

Carolina Gherman-Ciolac ◽

Rajeev Raghavan ◽

Ananth Viswanath ◽

...

Keyword(s):

Quality Of Life ◽

Mental Health ◽

Prospective Study ◽

Psychiatric Symptoms ◽

Poor Quality ◽

Considerable Proportion ◽

Thyroid Status ◽

A Prospective Study ◽

Anxiety Depression

Abstract Hyperthyroidism is known to be associated with psychiatric symptoms such as anxiety and depression, impartment of functioning and poor quality of life (QOL). It was intended to study the outcome of anxiety, depression, ability to work and QOL following the treatment of hyperthyroidism in endocrine clinic. In a prospective study, all newly referred hyperthyroidism patients with fully supressed TSH (<0.004 mIU/L) were followed up three monthly for more than a year. Besides the thyroid status and clinical assessment, they were assessed using Patient Health Questionnaire (PHQ)-9 for depression, Generalised Anxiety Disorder (GAD)-7 questionnaire for anxiety; EuroQoL (ED5D) for QOL and Work and Social Adjustment Scale (WSAS) to measure functional impairment. There were 177 participants (77.9% females), with a mean age of 50.1±15.6 years (range 16-86). Majority (88.7%) were having Grave’s disease and 11.3% had thyroid nodular disease; 10.2% had recurrent hyperthyroidism. At the baseline, anxiety was considered severe in 27.7%; similarly depression was moderately severe in 13.7% and severe in 14.9%. Although these decreased over time, considerable proportions continued to have these symptoms even after a year of treatment. A little over a quarter (26.6%) had beta-blockers at baseline and 9.0% had antidepressants; these proportions decreased reflecting symptomatic improvement. Proportions not-working changed from 28% to 18.2% within a year. WSAS suggested that the proportion with significant impairment changed from 46.7% to 34.6% (mean score change from 11.6 to 5.1). The EuroQoL mean score was 59.6 at the initial assessment which increased gradually to over 80. Most of these outcome parameters correlated with the improvement in thyroid status; however for many patients, mental health symptoms and functional impairments continued even after the thyroid tests became normal. Considerable proportion of patients with hyperthyroidism had anxiety, depression, functional impartment and poor quality of life; most of which improved with the course of anti-thyroid treatment; however a considerable proportion continued to have symptoms and impairments even after a year. This suggests the need for additional psychiatric intervention, probably early in the treatment to decrease the morbidity and improve QOL. Use of specific screening measures for psychiatric symptoms in the endocrinology clinics may be useful. References (1) Demet et al, Arch Med Res. 2002 Nov-Dec;33(6):552-6.

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Psychiatric Symptoms and Quality of Life in Systemic Sclerosis

Clinical Practice and Epidemiology in Mental Health ◽

10.2174/1745017901208010030 ◽

2012 ◽

Vol 8 (1) ◽

pp. 30-35 ◽

Cited By ~ 24

Author(s):

G Mura ◽

Krishna M Bhat ◽

A Pisano ◽

G Licci ◽

MG Carta

Keyword(s):

Quality Of Life ◽

Systemic Sclerosis ◽

Depressive Disorders ◽

Psychiatric Symptoms ◽

Physical Symptoms ◽

Poor Quality ◽

Point Of View ◽

High Rate ◽

Significant Impairment

Introduction: Systemic sclerosis (SSc) is a rare conjunctive tissue disorder characterized by fibrosis of the skin and internal organs, and vascular obliteration phenomena. Patients with SSc often experience elevated symptoms of psychological distress, determined by the disfiguration, the pain, the fatigue sensation, and the difficult in daily life occupations. The characteristics of the disease may influence the perceived quality of life (QoL) in people with SSc. Methods: This is a narrative review aiming to define the amount of impairment of Quality of Life in patients with Systemic Sclerosis and the component of this impairment due to depressive or other psychiatric symptoms. The search of the significant articles was carried out in PubMed for the key words “Psychiatric symptoms and Systemic Sclerosis”; “Quality of life and Systemic Sclerosis”; “Depressive Disorders and Systemic Sclerosis”. Results: Psychiatric symptoms are frequents in patients with SSc, but pain, fatigue, disability, body changes don’t appear to explain the high prevalence of psychiatric comorbidity in SSc. Many studies founded a significant impairment in SSc patients’ QoL, and despite the undeniable correlation between physical symptoms and SSc patients’ QoL, mental health was found significantly impaired. Discussion: The high rate of depression seems to strictly correlate with poor quality of life, and this finding needs more research to establish the cause of such a correlation. Patients’ point of view regarding their health-related QoL could help physicians to enlarge the knowledge about physical and mental correlates of the disease, and to fit therapies as patient required. Particular attention must be given to provide the patient with correct information, in order to mitigate the anxious state on disease course, and to enhance coping skills of the patients.

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KUALITAS HIDUP PASIEN STROKE DI POLIKLINIK RAWAT JALAN RUMAH SAKIT SWASTA YOGYAKARTA

Media Ilmu Kesehatan ◽

10.30989/mik.v7i3.274 ◽

2019 ◽

Vol 7 (3) ◽

pp. 232-237

Author(s):

Hana Larasati ◽

Theresia Titin Marlina

Keyword(s):

Quality Of Life ◽

Social Relations ◽

Hemorrhagic Stroke ◽

Poor Quality ◽

Social Dimension ◽

Stroke Patients ◽

Sampling System ◽

Post Stroke ◽

Psychological Dimension

Background: stroke is a disorder of nervous system function that occurs suddenly and is caused by brain bleeding disorders that can affect the quality of life physical dimensions, social dimensions, psychological dimensions, environmental dimensions. Based on the result of Lumbu study (2015) the number of samples were 71 people collected data using the (WHOQOL-BREF). There were 56 people (78,9%) had the poor quality of life of post stroke. The mean of post-stroke quality of life domain was physical domain (45,27%), psychological domain (49,87%), social relations domain (48,15%) and environmental domain (50.01%). Objective: the purpose of the study was know the quality of life of the stroke patients in Outpatient Polyclinic of Private Hospital in Yogyakarta. Methods: used descriptive quantitative by using questionnaire test of purposive sampling system based on patients who have been affected of ischemic or hemorrhagic stroke before, number 30 respondents. Result: quality of life of stroke patient of medium physical dimension (67%), psychological dimension (71%), social dimension (67%), dimension good environment (63%). Conclusion: the quality of life of stroke patients of physical dimension, psychological dimension, and moderate social dimension, while the quality of life of stroke patients were good environmental dimension. Keywords: Hemorrhagic stroke, ischemic stroke, quality of life

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Faculty Opinions recommendation of Factors associated with poor quality of life among cervical cancer survivors: implications for clinical care and clinical trials.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718634930.793502075 ◽

2014 ◽

Author(s):

David Kushner ◽

Laura Huffman

Keyword(s):

Quality Of Life ◽

Cervical Cancer ◽

Clinical Trials ◽

Cancer Survivors ◽

Clinical Care ◽

Poor Quality ◽

Factors Associated

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Impact of Depression and Anxiety on Dimensions of Health-Related Quality of Life in Subjects with Parkinson’s Disease Enrolled in an Association of Patients

Brain Sciences ◽

10.3390/brainsci11060771 ◽

2021 ◽

Vol 11 (6) ◽

pp. 771

Author(s):

Fany Chuquilín-Arista ◽

Tania Álvarez-Avellón ◽

Manuel Menéndez-González

Keyword(s):

Quality Of Life ◽

Parkinson’S Disease ◽

Parkinson's Disease ◽

Psychiatric Symptoms ◽

Well Being ◽

Depression And Anxiety ◽

Health Related Quality ◽

Related Quality ◽

Health Related

Parkinson’s disease (PD) is a complex disorder characterized by a wide spectrum of symptoms. Depression and anxiety are common manifestations in PD and may be determinants of health-related quality of life (HRQoL). The objective of this study is to determine the association of depression and anxiety with the dimensions of HRQoL in subjects with PD enrolled in an association of patients. Ninety-five community-based patients with PD diagnosis at different disease stages were studied. HRQoL was assessed using the Parkinson’s Disease Questionnaire (PDQ-39); depression and anxiety were assessed using the Beck Depression Inventory (BDI-II) and the State-Trait Anxiety Inventory (STAI), respectively. Our results showed that depression and anxiety were negatively associated with HRQoL measured by PDSI. Higher motor dysfunction measured by Hoehn and Yahr (H&Y) staging was also associated with worse HRQoL. Depression was the most influential variable in the model. All PDQ-39 dimensions except social support and bodily discomfort were associated with depression. Anxiety was associated with the emotional well-being and bodily discomfort dimensions. These results suggest that physicians should pay attention to the presence of psychiatric symptoms and treat them appropriately.

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Management of Traumatic Ulcerations of Lips in a Case of Huntington’s Disease: A Novel Application of Essix Retainer

The Journal of Indian Orthodontic Society ◽

10.1177/03015742211023469 ◽

2021 ◽

pp. 030157422110234

Author(s):

Mohamed Iqbal J

Keyword(s):

Quality Of Life ◽

Characteristic Feature ◽

Neurodegenerative Disease ◽

Huntington's Disease ◽

Huntington’S Disease ◽

Complete Resolution ◽

Psychiatric Symptoms

Huntington’s disease is a progressive neurodegenerative disease characterized by motor, cognitive, and psychiatric symptoms. Dystonia of muscles is a characteristic feature of this condition. A case of Huntington’s disease, with orofacial dystonia, leading to severe uncontrolled biting of the lips, was referred by the Department of Neurology. Deep traumatic ulcerations were found in both upper and lower lips. A simple Essix retainer was fabricated and inserted, which acted as a barrier for the teeth from injuring the lips. The ulcers showed complete resolution in 3 to 4 weeks. The vacuum-formed retainers resulted in a good fit and resisted removal by the uncontrolled contortions of the orofacial muscles. The Essix retainer can be effectively used in improving the quality of life of patients, with Huntington’s disease, having such dystonia-related injuries to lips.

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Affective Temperaments and Illness Severity in Patients with Bipolar Disorder

Medicina ◽

10.3390/medicina57010054 ◽

2021 ◽

Vol 57 (1) ◽

pp. 54

Author(s):

Mario Luciano ◽

Luca Steardo ◽

Gaia Sampogna ◽

Vito Caivano ◽

Carmen Ciampi ◽

...

Keyword(s):

Quality Of Life ◽

Bipolar Disorder ◽

Protective Factor ◽

Psychiatric Symptoms ◽

Control Group ◽

Term Outcome ◽

Long Term Outcome ◽

Affective Temperaments

Background and objectives: Bipolar disorder (BD) is one of the most burdensome psychiatric illnesses, being associated with a negative long-term outcome and the highest suicide rate. Although affective temperaments can impact on BD long-term outcome, their role remains poorly investigated. The aims of the present study are to describe the clinical characteristics of patients with BD more frequently associated with the different affective temperaments and to assess the relation between affective temperaments and severity of clinical picture in a sample of patients with BD. Materials and Methods: A total of 199 patients have been recruited in the outpatients units of two university sites. Patients’ psychiatric symptoms, affective temperaments, and quality of life were investigated through validated assessment instruments. Results: Predominant cyclothymic and irritable temperaments are associated to higher number of relapses, poorer quality of life, higher rates of aggressive behaviors, and suicide attempts. Conversely, the predominant hyperthymic disposition was a protective factor for several outcome measures, including relapse rate, severity of anxiety, depressive and manic symptoms, suicidality, and earlier age at onset. One limitationo of the present study is that the recruitment took place in two university sites; therefore, our findings cannot be fully generalized to the whole community of BD patients. Other limitations are the lack of a control group and the cross-sectional design of the study. Conclusions: The early identification of affective temperaments can help clinicians to identify those BD patients who are more likely to show a poor long-term outcome. An early screening of affective temperaments can be useful to develop targeted integrated pharmacological and psychosocial interventions.

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Quality of life, social support, and severity of psychiatric symptoms in Jordanian patients with schizophrenia

Journal of Psychiatric and Mental Health Nursing ◽

10.1111/jpm.12112 ◽

2013 ◽

Vol 21 (5) ◽

pp. 455-465 ◽

Cited By ~ 13

Author(s):

S. Hamaideh ◽

D. Al-Magaireh ◽

B. Abu-Farsakh ◽

H. Al-Omari

Keyword(s):

Quality Of Life ◽

Social Support ◽

Psychiatric Symptoms

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