Pulmonary embolism rule out: positivity and factors affecting the yield of CT angiography

ObjectiveCT pulmonary angiography (CTPA) is one of the most commonly ordered CT imaging tests. It is often believed to be overutilised with few recent studies showing a yield of less than 2%. This study aimed to determine the overall positivity rate of CTPA examinations and understand the factors that affect the yield of the CTPA examination.MethodsWe retrospectively analysed 2713 patients who received the CTPA exam between 2016 and 2018. Type of study ordered (CTPA chest or CTPA chest with abdomen and pelvis CT), patient location (emergency department (ED), outpatient, inpatient, intensive care unit (ICU)) and patient characteristics—age, sex and body mass index (BMI) were recorded. A logistic regression analysis was performed to determine what factors affect the positivity rate of CT scans for pulmonary embolism (PE).ResultsWith 296 positive test results, the overall CTPA positivity was 10.9%. Male sex was associated with higher CTPA positivity, gender difference was maximum in 18-year to 35-year age group. Overweight and obese patients had significantly higher positivity as compared with BMI<25 (p<0.05). Higher positivity rate was seen in the BMI 25–40 group (11.9%) as compared with BMI>40 (10.1%) (p<0.05). Significant difference (p<0.001) was also found in CTPA examination yield from ICU (15.3%) versus inpatients (other than ICU) (12.4%) versus ED (9.6%), and outpatients (8.5%). The difference in CTPA yield based on the type of CT order (CTPA chest vs CTPA chest with CT abdomen and pelvis), patient’s age and sex was not significant.ConclusionCTPA yield of 10.9% in this study is comparable to acceptable positivity rate for the USA and is higher than recent studies showing positivity of <2%. Patient characteristics like obesity and ICU or inpatient location are associated with higher rate of CT positivity.

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Determination Of Factors Affecting Father-Baby Attachment

Gevher Nesibe Journal, IESDR ◽

10.46648/gnj.245 ◽

2021 ◽

Vol 6 (14) ◽

pp. 1-7

Author(s):

Emine Serap ÇAĞAN ◽

Birsen KARACA SAYDAM ◽

Sinem GÜLÜMSER ATEŞ ◽

Rabia EKTİ GENÇ ◽

Esin ÇEBER TURFAN

Keyword(s):

Cross Sectional Study ◽

Study Data ◽

Cross Sectional ◽

Infant Attachment ◽

Factors Affecting ◽

Attachment Figure ◽

Gynecology And Obstetrics ◽

Significant Difference ◽

Package Program ◽

The Difference

Introduction: The primary attachment figure is mostly defined as the mother, and studies focus on the mother. However, in many babies, basic attachment is just as good with the father as with the mother. It is seen that there are very few studies in the literature investigating the correlations of father-infant attachment relationships.. The aim of this study is to determine the father-infant attachment status and to determine the factors affecting attachment. Method: The population of the cross-sectional study consisted of the spouses of all puerperant women hospitalized in the Gynecology and Obstetrics Clinic between September 1, 2018 and October 1, 2018. The sample size consisted of 156 fathers who agreed to participate in the study. Father identification form and father-infant attachment scale were used to collect the study data. The analysis of the data obtained from the research was carried out on the computer using the SPSS 16.0 package program. Results: 156 fathers participated in the study. The mean age of the fathers is 33.64±6.49, and 38.5% of them have a bachelor's degree. 91.0% of fathers stated that they felt ready for fatherhood. The fathers' Father-Infant Attachment Scale mean score was 82.60±7.72 In the analysis, the difference between the variables and the total score of the scale was found to be statistically insignificant (p>0.05). Discussion and Conclusion: At the end of the study, the bonding process of fathers participating in the study with their babies and the factors affecting this process were evaluated and it was seen that the father-infant attachment scale mean scores of the fathers participating in the study were high and were similar to other studies. In addition, when the basic factors affecting father-infant attachment were compared with the attachment scale mean score, it was found that there was no statistically significant difference.

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PENGARUH VARIASI KONSENTRASI EKSTRAK DAUN BELIMBING WULUH (Averrhoa bilimbi L) TERHADAP KARAKTERISTIK SEDIAAN SALEP DENGAN MENGGUNAKAN BASIS PEG 4000 dan PEG 400

Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) ◽

10.30587/herclips.v2i02.2394 ◽

2021 ◽

Vol 2 (02) ◽

pp. 7

Author(s):

Tri Puji Lestari

Keyword(s):

Leaf Extract ◽

Homogeneity Test ◽

Test Results ◽

Peg 400 ◽

Cell Tissue ◽

Peg 4000 ◽

Significant Difference ◽

Ointment Formulation ◽

The Difference ◽

One Way Anova

ABSTRAK Daun Belimbing Wuluh (Averrhoa bilimbi L) memiliki kandungan tanin dan flavonoid. Kandungan Flavonoid dan Tanin yang terdapat dalam belimbing wuluh mampu memberikan efek untuk menyembuhkan kulit yang mengalami kerusakan jaringan sel akibat luka bakar. Ada beberapa cara untuk pemanfaatan Daun Belimbing Wuluh antara lain dengan dibuat dalam sediaan salep. Pada penelitian ini salep dibuat dengan variasi konsentrasi ekstrak daun belimbing wuluh sebesar 10%, 15%, dan 20% mengguankan basis PEG 4000 dan PEG 400. Ekstrak daun belimbing wuluh diperoleh menggunakan metode maserasi dengan menggunakan etanol 70% sebagai pelarutnya. Salep yang sudah dibuat kemudian dilakukan uji karakteristik meliputi uji organoleptis, homogenitas, daya lekat dan uji daya sebar. Hasil uji organoleptis dan homogenitas di analisa secara deskrisptif kemudian hasil uji daya lekat dan uji daya sebar di analisa dengan menggunakan analisa statistik one-way ANOVA. Hasil penelitian menunjukan bahwa salep berbentuk semipadat dengan warna hijau muda sampai hijau kehitaman. Hasil uji homogenitas di dapatkan untuk ketiga formula adalah homogen. Nilai daya sebar pada ketiga formula menunjukan perbedaan yang signifikan, pada hasil uji daya lekat dan pH didapatkan tidak ada perbedaan yang signifikan terhadap ketiga formulasi. Dengan demikian perbedaan konsentrasi zat aktif yang digunakan berpengaruh terhadap daya sebar sediaan salep ekstrak daun belimbing wuluh. Kata kunci: Averrhoa bilimbi L; Salep; PEG ABSTRACT Carambola leaf Wuluh (Averrhoa bilimbi L) contains tannins and flavonoids. The content of flavonoids and tannins contained in starfruit able to give effect to heal skin damaged cell tissue from burns. There were several ways for utilization of Averrhoa bilimbi L. among others, made some preparations, especially ointment formulation. This study aims to formulate leaf extract ointment preparation starfruit (Averrhoa bilimbi L) with various concentrations of 10%, 15%, and 20% using the PEG 4000 and PEG 400 as a base. Leaf extract obtained from meserasi leaf Averrhoa bilimbi L with 70% ethanol. The ointment that has been made is then subjected to characteristic tests including organoleptic tests, homogeneity, adhesion and spreadability tests. The results of the organoleptic test and homogeneity were analyzed descriptively, then the results of the adhesion test and the spreadability test were analyzed using one-way ANOVA statistical analysis. The results showed that the ointment was semisolid, light green to blackish green. The homogeneity test results obtained for the three formulas are homogeneous. The value of the spreadability of the three formulas showed a significant difference, the results of the adhesion and pH test showed no significant difference between the three formulations. Thus the difference in the concentration of the active substance used affects the spreadability of the starfruit leaf extract ointment. Keywords: Averrhoa bilimbi L; ointment; PEG

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Assessment of Educational Game Materials and Poster Practices with Rubrics by Expert Educators and Students

Journal of Education and Training Studies ◽

10.11114/jets.v5i13.2855 ◽

2018 ◽

Vol 5 (13) ◽

pp. 79

Author(s):

Figen Altay ◽

Kevser Bozkurt

Keyword(s):

Correlation Analysis ◽

Educational Games ◽

Educational Game ◽

Test Results ◽

Knowledge Test ◽

Significant Difference ◽

Scoring Rubrics ◽

Sample Test ◽

The Difference ◽

Poster Presentations

The purpose of this study was to investigate the difference between evaluations of the educational game materials and poster practices by students’ own peers and by expert educators using the rubrics created by expert educators and students together. Study included 10 students and 3 educators attended educational game materials course. Students were informed about basic skills of movement, game, game types, game equipment, analytical rubric, and educational game lectures were given to the students for 6 weeks and 80 minutes each week. 12-question knowledge test was used regarding educational games, analytical scoring rubrics, developing game materials and preparing posters. Materials and posters presented in the course were recorded. Evaluation scales were selected by students and expert teachers. Selected peers and educators evaluated 25 videos. One-way analysis of variance and correlation analysis were used for the reliability and repeatability measurements of the students and teachers. R values of 0.96-0.92 were found between students and 0.78-0.86 between educators. For knowledge tests of the groups, according to Wilcoxon paired two-sample test, there was a significant difference in test results (p<.05). The t test was used in the results of the student and educator video evaluations and there was no significant difference between the scores given by the expert educators and the students to the material and poster presentations (p>.05). In conclusion, this study showed that students could make evaluations as good as expert educators when given an answer key such as a scoring rubric that will help them in the evaluation.

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Sleeve Gastrectomy vs. Fundus Resection in Bariatric Surgery (Animal Study)

Shiraz E-Medical Journal ◽

10.5812/semj.95198 ◽

2020 ◽

Vol 21 (6) ◽

Author(s):

Alimohammad Bananzadeh ◽

Seyed Vahid Hosseini ◽

Hajar Khazraei ◽

Mohammad Mehdi Lashkarizadeh ◽

Leila Ghahramani ◽

...

Keyword(s):

Bariatric Surgery ◽

Weight Loss ◽

Sleeve Gastrectomy ◽

Body Weight Loss ◽

Test Results ◽

Significant Difference ◽

Before And After ◽

Total Ghrelin ◽

The Difference ◽

High Level

Background: Bariatric surgery has resulted in body weight loss, which claimed by surgery removal specific parts of the stomach with enzyme or sleeve gastrectomy. Objectives: The aim of this study is to determine weight loss and endocrine changes by 12-week fundus resection and sleeve gastrectomy in rabbits. Methods: Twenty-one rabbits, weighing 2.5 - 3.5 kg, were divided into three groups (n = 7): sleeve gastrectomy, experimental fundus resection, and sham group. The weight of rabbits and total ghrelin and leptin levels in the plasma before and after surgery were measured in 12 weeks. Statistical analyses were performed using the Kruskal-Walis test for comparison of the means between the groups, and the difference after months in one group was assayed by Friedman test. Results: The results showed sleeve gastrectomy had a significant weight loss after one month when compared to fundus resection and sham-operated controls (P = 0.008). There was no significant difference in the ghrelin levels after these surgeries, but leptin levels decreased significantly after the fundectomy (P = 0.025). Conclusions: Sleeve gastrectomy is more efficient than the fundus resection in weight loss. It could be suggested as a new option in metabolic disorders due to the high level of leptin.

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Gender-related differences in clinical presentation, electrocardiography signs, laboratory markers and outcome in patients with acute pulmonary embolism

Vojnosanitetski pregled ◽

10.2298/vsp150716093o ◽

2016 ◽

Vol 73 (9) ◽

pp. 844-849 ◽

Cited By ~ 1

Author(s):

Slobodan Obradovic ◽

Boris Dzudovic ◽

Sinisa Rusovic ◽

Vesna Subota ◽

Dragana Obradovic

Keyword(s):

Pulmonary Embolism ◽

Acute Pulmonary Embolism ◽

Clinical Presentation ◽

Univariate Analysis ◽

Pulmonary Angiography ◽

Laboratory Findings ◽

Laboratory Markers ◽

Significant Difference ◽

Echocardiographic Examination ◽

Gender Specific Differences

Background/Aim. Acute pulmonary embolism (PE) is a potentially life threating event, but there are scarce data about genderrelated differences in this condition. The aim of this study was to identify gender-specific differences in clinical presentation, the diagnosis and outcome between male and female patients with PE. Methods. We analysed the data of 144 consecutive patients with PE (50% women) and compared female and male patients regarding clinical presentation, electrocardiography (ECG) signs, basic laboratory markers and six-month outcome. All the patients confirmed PE by visualized thrombus on the multidetector computed tomography with pulmonary angiography (MDCTPA), ECG and echocardiographic examination at admission. Results. Compared to the men, the women were older and a larger proportion of them was in the third tertile of age (66.0% vs 34.0%, p = 0.008). In univariate analysis the men more often had hemoptysis [OR (95% CI) 3.75 (1.16-12.11)], chest pain [OR (95% CI) 3.31 (1.57-7.00)] febrile state [OR (95% CI) 2.41 (1.12-5.22)] and pneumonia at PE presentation [OR (95% CI) 3.40 (1.25-9.22)] and less likely had heart decompensation early in the course of the disease [OR (95%CI) 0.48 (0.24-0.97)]. In the multivariate analysis a significant difference in the rate of pneumonia and acute heart failure between genders disappeared due to strong influence of age. There was no significant difference in the occurrence of typical ECG signs for PE between the genders. Women had higher level of admission glycaemia [7.7 mmol/L (5.5-8.2 mmol/L) vs 6.9 mmol/L (6.3-9.6 mmol/L), p = 0.006] and total number of leukocytes [10.5 x 109/L (8.8-12.7 x 109/L vs 8.7 x 109/L (7.0-11.6 x 109/L)), p = 0.007]. There was a trend toward higher plasma level of brain natriuretic peptide in women compared to men 127.1 pg/mL (55.0-484.0 pg/mL), p = 0.092] vs [90.3 pg/mL (39.2-308.5 pg/mL). The main 6-month outcomes, death and major bleeding, had similar frequencies in both sexes. Conclusion. There are several important differences between men and women in the clinical presentation of PE and basic laboratory findings which can influence the diagnosis and treatment of PE.

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Wear Comparison of a Plain Toothbrush versus Eleven Commercial Toothbrushes

Open Access Journal of Dental Sciences ◽

10.23880/oajds-16000311 ◽

2021 ◽

Vol 6 (4) ◽

Author(s):

Natasha Fansiwala BS

Keyword(s):

Rating Scale ◽

Subjective Rating ◽

Test Results ◽

Posterior Teeth ◽

Whitney Test ◽

Significant Difference ◽

Manual Toothbrush ◽

The Difference ◽

Subjective Rating Scale ◽

Wear Index

Objective: To compare the wear of the Sound Feelings SOFT Plain Toothbrush 47 tuft (flat bristles) versus eleven manual toothbrushes. Methods: Twelve brand-new manual toothbrushes (n = 35 in each group) were used for comparison. Each toothbrush was run on a toothbrushing simulator with a brushing force of 2N for approximately 2 hours to simulate 1 month of toothbrushing (9,333 strokes @ 45° lingual of posterior teeth, 9,333 strokes on the top surface, and 9,333 strokes @ 45° buccal of posterior teeth), using the Bass technique on a quadrant typodont. Wear was measured by wear index and wear rating. The Wear index measures the degree of bristle splaying whereby the bristles spread apart and take on a permanent curvature. Wear rating is a subjective rating scale consisting of a series of four numbers increasing from zero to three. The Olympus SZX16 microscope was used to measure the wear rating then was inputted into a formula and averaged. The subjective wear seen as bristle splay/ curling was also measured and recorded. Comparison of the wear index and wear rating between each manual toothbrush was conducted using the Mann-Whitney test. Results: Wear index and wear rating for all toothbrushes ranged from 0.03 to 0.34 and from 0.57 to 2.06, respectively. There was a significant difference in the wear index between each toothbrush and the Sound Feelings SOFT Plain toothbrush. The difference in the wear rating was significant between the Sound Feelings SOFT Plain toothbrush and all other toothbrushes other than the Reach Advanced Design Soft toothbrush. Conclusion: The Sound Feelings SOFT Plain Toothbrush had the lowest wear rating and index among all the manual toothbrushes tested.

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Predicting the Loose Zone of Roadway Surrounding Rock Using Wavelet Relevance Vector Machine

Applied Sciences ◽

10.3390/app9102064 ◽

2019 ◽

Vol 9 (10) ◽

pp. 2064 ◽

Cited By ~ 7

Author(s):

Yang Liu ◽

Yicheng Ye ◽

Qihu Wang ◽

Xiaoyun Liu ◽

Weiqi Wang

Keyword(s):

Relevance Vector Machine ◽

Surrounding Rock ◽

Prediction Errors ◽

Test Results ◽

Factors Affecting ◽

Relevance Vector Machines ◽

Five Factors ◽

Vector Machines ◽

Practical Engineering ◽

The Difference

By applying the Wavelet Relevance Vector Machine (WRVM) method, this research proposes the loose zone of roadway surrounding rock prediction. Based on the theory of relevance vector machine (RVM), the wavelet function is introduced to replace the original Gauss function as the model kernel function to form the WRVM. Five factors affecting the loose zone of roadway surrounding rock are selected as the model input, and the prediction model of the loose zone of roadway surrounding rock based on WRVM is established. By using cross-validation method, the kernel parameters of three kinds of wavelet relevance vector machines (RVMs) are calculated. By comparing and analyzing the root mean square (RMS) error of the test results of each predictive model, the advantages and accuracy of the model are verified. In practical engineering applications, the average relative prediction errors of the Mexican relevance vector machine, the Morlet relevance vector machine and the difference of Gaussian (DOG) relevance vector machine models are accordingly 4.581%, 4.586% and 4.575%. The square correlation coefficient of the predicted samples is 0.95 > 0.9, which further verifies the accuracy and reliability of the proposed method.

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Critical Bandwidth and Sensitivity Prediction in the Acoustic Stapedial Reflex

Journal of Speech and Hearing Disorders ◽

10.1044/jshd.4102.244 ◽

1976 ◽

Vol 41 (2) ◽

pp. 244-255 ◽

Cited By ~ 5

Author(s):

Daniel M. Schwartz ◽

Jay W. Sanders

Keyword(s):

Hearing Loss ◽

Hearing Impaired ◽

Test Results ◽

Acoustic Reflex ◽

Severe Hearing Loss ◽

Critical Bandwidth ◽

Significant Difference ◽

Stapedial Reflex ◽

The Difference ◽

The Relationship

Critical bandwidth measurements and sensitivity prediction from the acoustic reflex (SPAR) test results were obtained on 20 normal-hearing and two groups of 10 hearing-impaired subjects each representing mild-to-moderate and severe hearing loss. Results of critical bandwidth measurements indicated that for center frequencies of 1000 and 2000 Hz the critical bandwidth was significantly greater for the hearing-impaired subjects. A statistical analysis of the difference in critical bandwidth between those predicted by the SPAR test to have a mild-to-moderate hearing loss and those subjects for whom the test predicted severe hearing loss indicated no differences in critical bandwidth at 2000 Hz. A significant difference was found at 1000 Hz but in the wrong direction. Analysis of the relationship between predicted slope of hearing loss and critical bandwidth also failed to show significance. Although the data for hearing-impaired subjects fail to support the rationale for the SPAR test, the results for the entire research sample offer substantial support. Further, the ability of the test to predict categorically degree of hearing loss was also strongly supported.

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Salbutamol nebulization for management of transient tachypnea of newborn (TTN).

The Professional Medical Journal ◽

10.29309/tpmj/2021.28.01.4614 ◽

2021 ◽

Vol 28 (01) ◽

pp. 52-59

Author(s):

Fatima Maroof ◽

Tehmina Maqbool ◽

Hafiz Muhammad Irfan ◽

Beenish Bashir Mughal ◽

Ayesha ◽

...

Keyword(s):

Placebo Group ◽

Respiratory Rate ◽

Test Results ◽

Demographic Information ◽

Significant Difference ◽

Nebulized Salbutamol ◽

The Mean ◽

Randomized Control ◽

The Difference ◽

Trial Setting

Objective: To compare the mean change in respiratory rate with salbutamol nebulization versus placebo for treatment of transient tacyopnea of newborn. Study Design: Randomized Control Trial. Setting: Department of Neonatology, Federal Government Polyclinic (PGMI), Islamabad. Period: 8th August 2017 to 7th February 2018. Material & Methods: 100 neonates fulfilling selection criteria were enrolled in the study. Informed consent was obtained from parents. Demographic information was also noted. All baseline respiratory rate were noted. Neonates were divided into two groups by lottery method. Neonates in Treatment group were nebulized with Salbutamol. Placebo group was nebulized with Normal Saline. Then neonates were followed-up in N.I.C.U after 4 hours of second nebulization. After 4 hours, respiratory rates were assessed and change in respiratory rate was noted. Both groups were compared for mean reduction in respiratory rate by using independent sample t-test. Results: In nebulized salbutamol, group, mean respiratory rate was changed from 79.62±8.18bpm to 52.06±4.96bpm. This was a significant decrease (p<0.05). In placebo group, mean respiratory rate was changed from 81.88±8.86bpm to 62.50±6.75bpm. This was significant decrease (p<0.05). The difference between both groups at baseline was insignificant while after 4 hours was significant. The mean changed in respiratory rate with nebulized salbutamol was 27.56±6.83bpm while with placebo was 19.35±9.83bpm. There was significant difference in mean reduction in respiratory rate (p<0.05). Conclusion: It has been proved that nebulized salbutamol can be helpful in reducing respiratory rate significantly in neonates with TTN as compared to placebo.

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