scholarly journals PENGARUH VARIASI KONSENTRASI EKSTRAK DAUN BELIMBING WULUH (Averrhoa bilimbi L) TERHADAP KARAKTERISTIK SEDIAAN SALEP DENGAN MENGGUNAKAN BASIS PEG 4000 dan PEG 400

2021 ◽  
Vol 2 (02) ◽  
pp. 7
Author(s):  
Tri Puji Lestari
Keyword(s):  
Leaf Extract ◽  
Homogeneity Test ◽  
Test Results ◽  
Peg 400 ◽  
Cell Tissue ◽  
Peg 4000 ◽  
Significant Difference ◽  
Ointment Formulation ◽  
The Difference ◽  
One Way Anova

ABSTRAK Daun Belimbing Wuluh (Averrhoa bilimbi L) memiliki kandungan tanin dan flavonoid. Kandungan Flavonoid dan Tanin yang terdapat dalam belimbing wuluh mampu memberikan efek untuk menyembuhkan kulit yang mengalami kerusakan jaringan sel akibat luka bakar. Ada beberapa cara untuk pemanfaatan Daun Belimbing Wuluh antara lain dengan dibuat dalam sediaan salep. Pada penelitian ini salep dibuat dengan variasi konsentrasi ekstrak daun belimbing wuluh sebesar 10%, 15%, dan 20%  mengguankan basis PEG 4000 dan PEG 400. Ekstrak daun belimbing wuluh diperoleh menggunakan metode maserasi dengan menggunakan etanol 70% sebagai pelarutnya. Salep yang sudah dibuat kemudian dilakukan uji karakteristik meliputi uji organoleptis, homogenitas, daya lekat dan uji daya sebar. Hasil uji organoleptis dan homogenitas di analisa secara deskrisptif kemudian hasil uji daya lekat dan uji daya sebar di analisa dengan menggunakan analisa statistik one-way ANOVA.  Hasil penelitian menunjukan bahwa salep berbentuk semipadat dengan warna hijau muda sampai hijau kehitaman. Hasil uji homogenitas di dapatkan untuk ketiga formula adalah homogen. Nilai daya sebar pada ketiga formula menunjukan perbedaan yang signifikan, pada hasil uji daya lekat dan pH didapatkan tidak ada perbedaan yang signifikan terhadap ketiga formulasi. Dengan demikian perbedaan konsentrasi zat aktif yang digunakan berpengaruh terhadap daya sebar sediaan salep ekstrak daun belimbing wuluh. Kata kunci: Averrhoa bilimbi L; Salep; PEG   ABSTRACT Carambola leaf Wuluh (Averrhoa bilimbi L) contains tannins and flavonoids. The content of flavonoids and tannins contained in starfruit able to give effect to heal skin damaged cell tissue from burns. There were several ways for  utilization  of  Averrhoa  bilimbi  L.  among  others,  made  some  preparations, especially ointment formulation. This study aims to formulate leaf extract ointment preparation starfruit (Averrhoa bilimbi L) with various concentrations of 10%, 15%, and 20% using the PEG 4000 and PEG 400 as a base. Leaf extract obtained from meserasi leaf Averrhoa bilimbi  L  with  70%  ethanol. The ointment that has been made is then subjected to characteristic tests including organoleptic tests, homogeneity, adhesion and spreadability tests. The results of the organoleptic test and homogeneity were analyzed descriptively, then the results of the adhesion test and the spreadability test were analyzed using one-way ANOVA statistical analysis. The results showed that the ointment was semisolid, light green to blackish green. The homogeneity test results obtained for the three formulas are homogeneous. The value of the spreadability of the three formulas showed a significant difference, the results of the adhesion and pH test showed no significant difference between the three formulations. Thus the difference in the concentration of the active substance used affects the spreadability of the starfruit leaf extract ointment. Keywords: Averrhoa bilimbi L; ointment; PEG

scholarly journals DAYA HAMBAT EKSTRAK DAUN KARI TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus

2018 ◽  
Vol 10 (3) ◽  
pp. 287-291
Author(s):  
Lisna Unita ◽  
Colvin Voon
Keyword(s):  
Staphylococcus Aureus ◽  
Leaf Extract ◽  
Inhibition Zone ◽  
Test Method ◽  
Control Group ◽  
Test Results ◽  
Control Group Design ◽  
Extract Solution ◽  
Significant Difference ◽  
The Difference

Curry leaves ( Murraya koenigii ) can be used as a spice in cooking and curry leaf extract , has the effect of antimicrobial activity can inhibit the growth of Staphylococcus aureus . The purpose of this study was to determine the curry leaf extract solution of various concentrations to inhibit the growth of Staphylococcus aureus and know the difference inhibition curry leaf extract solution between the various different concentrations on the growth of Staphylococcus aureus . This study uses laboratory Experimental design by Design Posttest only control group design . Test method using agar diffusion techniques and media used are media Mueller Hinton Agar ( MHA ) containing Staphylococcus aureus . After incubation for 24 hours and then measure the inhibition zone which formed . One Way Anova Test results obtained curry leaf extract solutions were made in different concentrations of 2.5 % , 5 % , 7.5 % and 10 % can inhibit the growth of Staphylococcus aureus . The higher concentration of curry leaf extract greater inhibitory power and show stronger antibacterial activity . Multiple Comparison Test Results ( LSD ) significant difference ( p < 0.05 ) between the inhibition of curry leaf extract 2.5 % to 10 % , with a value of p = 0.002 , and curry leaf extract 5 % to 10 % with the value of p = 0.007.

scholarly journals PENGARUH EKSTRAK DAUN SIRSAK (Annona muricata Zinn) TERHADAP PERKEMBANGAN LARVA Aedes aegypti

2018 ◽  
Vol 8 (2) ◽  
pp. 167-172
Author(s):  
Susiwati Susiwati
Keyword(s):  
Aedes Aegypti ◽  
Leaf Extract ◽  
Research Needs ◽  
Annona Muricata ◽  
Test Results ◽  
Extract Concentration ◽  
Quasi Experimental ◽  
The Difference ◽  
One Way Anova ◽  
Different Levels

Soursop plants is a plant that is widely available in Indonesia. In addition tofruit that can be directly consumed. The main content of soursop is active compounds annonaceusacetogenin. The leaves are most part annonaceus acetogenin containing compoundsthat are known to have the effect of insecticide, antifeedant repelant and works as acontact and stomach poison toxin in Aedes aegypti larvae. The purpose of this study was todetermine the effect of extract of soursop’s leaves (Annona muricata Zinn) as larvicides ofAedes aegypti in different levels of concentrations. This research is quasi-experimental. Thesamples used were 600 instar larvae of Aedes aegypti III/IV. Each treatment containing 25larvae and repetition as much as 4 times. Soursop leaf extract concentration tested, namely 0%(control), 5%, 10%, 15%, 20%, and 25%. The result is the number of Aedes aegypti larvaewere dead after 24 hours in each concentration group. Greatest death in a concentration of25% is as much as 92%, while the lowest mortality at a concentration of 5% is as much as15%. The results of the study were further tested with One Way Anova. Statistical test resultsobtained with One Way Anova sig. = 0.000 so that ρ < α (0.05) means that there is a significanteffect on the difference in average number of larvae mortality in each treatment groupbecause of increasing the concentration. LSD test results showed a mean difference significantat the 0.05 level. From the results of this research community can use extract of soursop’sleaves with a concentration of 25% as an alternative to eradication of Aedes aegypti is a vectorof Dengue Fever (DHF). Further research needs to be done on the toxicology and safety ofsoursop leaf extract as an alternative to the eradication of Aedes aegypti mosquito larvae

scholarly journals The Effect of Extract Supplements of Moringa Oleifera Leaves Plus Royal Jelly on Hemoglobin (Hb) Levels of Anemia Pregnant Mother in Takalar Regency

2020 ◽  
Vol 1 (2) ◽  
pp. 22-29
Author(s):  
Yulni Yulni ◽  
Veni Hadju ◽  
Burhanuddin Bahar ◽  
Citrakesumasari Citrakesumasari ◽  
Rahayu Indriasari ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Leaf Extract ◽  
Moringa Oleifera ◽  
Royal Jelly ◽  
P Value ◽  
Double Blind ◽  
Significant Difference ◽  
Before And After ◽  
The Difference ◽  
Double Blind Design

The aim of this study was to determine the effect of Moringa oleifera leaf extract supplements, Moringa oleifera leaf extract plus royal jelly and placebo on hemoglobin levels in anemic pregnant women. This research is a randomized controlled double blind design study which was conducted in Polombangkeng Utara District, Takalar Regency for 2 months. The subjects of this study were pregnant women with anemia, the majority of which were 20-35 years old, primigravida parity, income less than UMR, unemployment, higher education, pregnancy distance of more than 2 years with p value> 0.05. Then divided into three groups, namely Moringa capsules plus royal jelly (KRJ) (n = 24), Moringa capsules (KTR) (n = 24) and placeco (PLC) (n = 21). Before and after the intervention, measurements of hemoglobin levels were carried out using the Hemocue tool and interviewing the characteristics of the respondents. The results showed that the average Hb level increased from each group (mean SD): KRJ 10.06 ± 0.75 to 11.42 ± 1.23, P = 0.001, KTR 10.40 ± 0.46 to 11.15 ± 0 , 90 P = 0.001 and PLC 10.43 ± 0.42 becomes 11.14 ± 0.88 P = 0.002. but there was no significant difference from the difference in the average increase in Hb levels in the three groups, but there was a tendency that KRJ was superior to the KTR and PLC groups with an increase of 1.36 gr / dl, KTR 0.75 gr / dl and PLC 0.71 gr / dl. So it can be concluded that KRJ is better than KTR and PLC in increasing Hb levels in anemic pregnant women in Takalar Regency.

scholarly journals Assessment of Educational Game Materials and Poster Practices with Rubrics by Expert Educators and Students

2018 ◽  
Vol 5 (13) ◽  
pp. 79
Author(s):  
Figen Altay ◽  
Kevser Bozkurt
Keyword(s):  
Correlation Analysis ◽  
Educational Games ◽  
Educational Game ◽  
Test Results ◽  
Knowledge Test ◽  
Significant Difference ◽  
Scoring Rubrics ◽  
Sample Test ◽  
The Difference ◽  
Poster Presentations

The purpose of this study was to investigate the difference between evaluations of the educational game materials and poster practices by students’ own peers and by expert educators using the rubrics created by expert educators and students together. Study included 10 students and 3 educators attended educational game materials course. Students were informed about basic skills of movement, game, game types, game equipment, analytical rubric, and educational game lectures were given to the students for 6 weeks and 80 minutes each week. 12-question knowledge test was used regarding educational games, analytical scoring rubrics, developing game materials and preparing posters. Materials and posters presented in the course were recorded. Evaluation scales were selected by students and expert teachers. Selected peers and educators evaluated 25 videos. One-way analysis of variance and correlation analysis were used for the reliability and repeatability measurements of the students and teachers. R values of 0.96-0.92 were found between students and 0.78-0.86 between educators. For knowledge tests of the groups, according to Wilcoxon paired two-sample test, there was a significant difference in test results (p<.05). The t test was used in the results of the student and educator video evaluations and there was no significant difference between the scores given by the expert educators and the students to the material and poster presentations (p>.05). In conclusion, this study showed that students could make evaluations as good as expert educators when given an answer key such as a scoring rubric that will help them in the evaluation.

scholarly journals Sleeve Gastrectomy vs. Fundus Resection in Bariatric Surgery (Animal Study)

2020 ◽  
Vol 21 (6) ◽  
Author(s):  
Alimohammad Bananzadeh ◽  
Seyed Vahid Hosseini ◽  
Hajar Khazraei ◽  
Mohammad Mehdi Lashkarizadeh ◽  
Leila Ghahramani ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Weight Loss ◽  
Sleeve Gastrectomy ◽  
Body Weight Loss ◽  
Test Results ◽  
Significant Difference ◽  
Before And After ◽  
Total Ghrelin ◽  
The Difference ◽  
High Level

Background: Bariatric surgery has resulted in body weight loss, which claimed by surgery removal specific parts of the stomach with enzyme or sleeve gastrectomy. Objectives: The aim of this study is to determine weight loss and endocrine changes by 12-week fundus resection and sleeve gastrectomy in rabbits. Methods: Twenty-one rabbits, weighing 2.5 - 3.5 kg, were divided into three groups (n = 7): sleeve gastrectomy, experimental fundus resection, and sham group. The weight of rabbits and total ghrelin and leptin levels in the plasma before and after surgery were measured in 12 weeks. Statistical analyses were performed using the Kruskal-Walis test for comparison of the means between the groups, and the difference after months in one group was assayed by Friedman test. Results: The results showed sleeve gastrectomy had a significant weight loss after one month when compared to fundus resection and sham-operated controls (P = 0.008). There was no significant difference in the ghrelin levels after these surgeries, but leptin levels decreased significantly after the fundectomy (P = 0.025). Conclusions: Sleeve gastrectomy is more efficient than the fundus resection in weight loss. It could be suggested as a new option in metabolic disorders due to the high level of leptin.

scholarly journals Wear Comparison of a Plain Toothbrush versus Eleven Commercial Toothbrushes

2021 ◽  
Vol 6 (4) ◽  
Author(s):  
Natasha Fansiwala BS
Keyword(s):  
Rating Scale ◽  
Subjective Rating ◽  
Test Results ◽  
Posterior Teeth ◽  
Whitney Test ◽  
Significant Difference ◽  
Manual Toothbrush ◽  
The Difference ◽  
Subjective Rating Scale ◽  
Wear Index

Objective: To compare the wear of the Sound Feelings SOFT Plain Toothbrush 47 tuft (flat bristles) versus eleven manual toothbrushes. Methods: Twelve brand-new manual toothbrushes (n = 35 in each group) were used for comparison. Each toothbrush was run on a toothbrushing simulator with a brushing force of 2N for approximately 2 hours to simulate 1 month of toothbrushing (9,333 strokes @ 45° lingual of posterior teeth, 9,333 strokes on the top surface, and 9,333 strokes @ 45° buccal of posterior teeth), using the Bass technique on a quadrant typodont. Wear was measured by wear index and wear rating. The Wear index measures the degree of bristle splaying whereby the bristles spread apart and take on a permanent curvature. Wear rating is a subjective rating scale consisting of a series of four numbers increasing from zero to three. The Olympus SZX16 microscope was used to measure the wear rating then was inputted into a formula and averaged. The subjective wear seen as bristle splay/ curling was also measured and recorded. Comparison of the wear index and wear rating between each manual toothbrush was conducted using the Mann-Whitney test. Results: Wear index and wear rating for all toothbrushes ranged from 0.03 to 0.34 and from 0.57 to 2.06, respectively. There was a significant difference in the wear index between each toothbrush and the Sound Feelings SOFT Plain toothbrush. The difference in the wear rating was significant between the Sound Feelings SOFT Plain toothbrush and all other toothbrushes other than the Reach Advanced Design Soft toothbrush. Conclusion: The Sound Feelings SOFT Plain Toothbrush had the lowest wear rating and index among all the manual toothbrushes tested.

Critical Bandwidth and Sensitivity Prediction in the Acoustic Stapedial Reflex

1976 ◽  
Vol 41 (2) ◽  
pp. 244-255 ◽  
Author(s):  
Daniel M. Schwartz ◽  
Jay W. Sanders
Keyword(s):  
Hearing Loss ◽  
Hearing Impaired ◽  
Test Results ◽  
Acoustic Reflex ◽  
Severe Hearing Loss ◽  
Critical Bandwidth ◽  
Significant Difference ◽  
Stapedial Reflex ◽  
The Difference ◽  
The Relationship

Critical bandwidth measurements and sensitivity prediction from the acoustic reflex (SPAR) test results were obtained on 20 normal-hearing and two groups of 10 hearing-impaired subjects each representing mild-to-moderate and severe hearing loss. Results of critical bandwidth measurements indicated that for center frequencies of 1000 and 2000 Hz the critical bandwidth was significantly greater for the hearing-impaired subjects. A statistical analysis of the difference in critical bandwidth between those predicted by the SPAR test to have a mild-to-moderate hearing loss and those subjects for whom the test predicted severe hearing loss indicated no differences in critical bandwidth at 2000 Hz. A significant difference was found at 1000 Hz but in the wrong direction. Analysis of the relationship between predicted slope of hearing loss and critical bandwidth also failed to show significance. Although the data for hearing-impaired subjects fail to support the rationale for the SPAR test, the results for the entire research sample offer substantial support. Further, the ability of the test to predict categorically degree of hearing loss was also strongly supported.

scholarly journals Salbutamol nebulization for management of transient tachypnea of newborn (TTN).

2021 ◽  
Vol 28 (01) ◽  
pp. 52-59
Author(s):  
Fatima Maroof ◽  
Tehmina Maqbool ◽  
Hafiz Muhammad Irfan ◽  
Beenish Bashir Mughal ◽  
Ayesha ◽  
...  
Keyword(s):  
Placebo Group ◽  
Respiratory Rate ◽  
Test Results ◽  
Demographic Information ◽  
Significant Difference ◽  
Nebulized Salbutamol ◽  
The Mean ◽  
Randomized Control ◽  
The Difference ◽  
Trial Setting

Objective: To compare the mean change in respiratory rate with salbutamol nebulization versus placebo for treatment of transient tacyopnea of newborn. Study Design: Randomized Control Trial. Setting: Department of Neonatology, Federal Government Polyclinic (PGMI), Islamabad. Period: 8th August 2017 to 7th February 2018. Material & Methods: 100 neonates fulfilling selection criteria were enrolled in the study. Informed consent was obtained from parents. Demographic information was also noted. All baseline respiratory rate were noted. Neonates were divided into two groups by lottery method. Neonates in Treatment group were nebulized with Salbutamol. Placebo group was nebulized with Normal Saline. Then neonates were followed-up in N.I.C.U after 4 hours of second nebulization. After 4 hours, respiratory rates were assessed and change in respiratory rate was noted. Both groups were compared for mean reduction in respiratory rate by using independent sample t-test. Results: In nebulized salbutamol, group, mean respiratory rate was changed from 79.62±8.18bpm to 52.06±4.96bpm. This was a significant decrease (p<0.05). In placebo group, mean respiratory rate was changed from 81.88±8.86bpm to 62.50±6.75bpm. This was significant decrease (p<0.05). The difference between both groups at baseline was insignificant while after 4 hours was significant. The mean changed in respiratory rate with nebulized salbutamol was 27.56±6.83bpm while with placebo was 19.35±9.83bpm. There was significant difference in mean reduction in respiratory rate (p<0.05). Conclusion: It has been proved that nebulized salbutamol can be helpful in reducing respiratory rate significantly in neonates with TTN as compared to placebo.

scholarly journals The Basic Motion Learning Model of Small Game Based Throwing in Elementary School

2021 ◽  
Vol 5 (2) ◽  
pp. 95
Author(s):  
Gunawan Setiawan ◽  
Syamsuramel Syamsuramel ◽  
Silvi Aryanti
Keyword(s):  
Elementary School ◽  
Learning Model ◽  
Small Scale ◽  
Test Results ◽  
Small Game ◽  
Motion Learning ◽  
Significant Difference ◽  
Post Test ◽  
The Difference ◽  
Basic Motion

This study aims to develop a small game-based basic motion learning model at Elementary School Number 65 Rejang Lebong. The research method used is research and development (R&D) using ten stages from Borg and Gall. The research instruments used were locomotor, non-locomotor tests, and manipulative basic movement skills tests. The treatment in this study was in the form of a basic motion learning model based on small games given for 4 weeks. The subjects in this study were students in grades 4 and 5 of Elementary School Number 65 Rejang Lebong. Subjects in this study were 30 people. The validation results obtained in small-scale trials regarding the quality of the learning model have entered into the validation criteria filled by the validator with a percentage of 63% and the results of large group trials are declared valid with a percentage of 81.25% which means very feasible. Furthermore, the effectiveness test was carried out using the t-test. In the significance test of the difference using the SPSS tool, the mean value = 0.8666 which shows the difference between the pre-test and post-test results, the results of T-count = 13.730, df = 29, and P-Value = 0.000 <0.05, which means that there are There is a significant difference between before and after being treated with the small game-based learning model of throwing basic motion learning. Where the post-test results have positive results with a significant difference compared to the pre-test results. So that the learning model of the basic motion of throwing based on small games can be used in learning physical education and health in elementary schools. The implication of this research is that the basic motion learning model of throwing based on small games can be used as a form of learning the basic motion of throwing in elementary school children.

scholarly journals Stomach Volume Evaluation on Fetal MRI and its use in Prenatal Identification of Esophageal Atresia

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Aditya Phadnis ◽  
Monica Forbes-Amrhein
Keyword(s):  
Esophageal Atresia ◽  
Fetal Mri ◽  
Third Trimester ◽  
Linear Measurements ◽  
Significant Difference ◽  
The Difference ◽  
Magnetic Resonance Imaging Mri ◽  
Stomach Volume ◽  
Post Hoc ◽  
One Way Anova

Swallowing of amniotic fluid alters the volume of the fetal stomach; therefore an abnormal fetal stomach size can be indicative of pathology. Previous studies have used linear measurements on ultrasound to approximate stomach sizes. Fetal magnetic resonance imaging (MRI) allows for volumetric measurement of the stomach. The objective of this study was to develop a library of normal fetal stomach volumes on MRI at each gestational age. We also sought to measure stomach volumes of fetuses with esophageal atresia and compare to normal volumes at similar gestation ages (GA).  A retrospective review of fetal MRIs from patients 20-38 weeks GA was conducted.  Exclusion criteria for the controls included any impairment that would impede swallowing or alter stomach sizes.  Patients with esophageal atresia were identified and postnatal records were reviewed to confirm the diagnosis. The stomach volume was measured on T2-weighted imaging using Phillips Intellispace software. The stomach volumes of the controls at each GA were compared using one-way ANOVA with Games-Howell Post-Hoc (p<0.05).  The stomach volume in esophageal atresia was compared to controls using a T-test (p<0.001).    185 control studies, 10 at each week of gestation, and 8 patients with esophageal atresia were included. For normal fetuses, there was a trend of increased stomach size and broadened standard deviation with increasing GA.  No significant difference was found between any two sequential weeks, however the difference in second and third trimester volumes was significant (p<0.001).   The patients with esophageal atresia had significantly smaller stomach volumes compared to control patients of the same GA range (p<0.001).   This pilot study established reference values for fetal stomach volume, which was found to increase with GA. The stomach volume is significantly smaller in patients with esophageal atresia.  Thus, esophageal atresia can be identified prenatally, allowing for delivery at an appropriate acuity NICU and early intervention.   

Sign in / Sign up

Export Citation Format

Share Document