Termination of diapause in the larva of Lucilia caesar L. (Diptera: Calliphoridae)

1968 ◽  
Vol 46 (3) ◽  
pp. 335-344 ◽  
Author(s):  
Richard A. Ring

The sheep blowfly, Lucilia caesar L., enters a facultative diapause at the end of the third larval instar immediately before puparium formation. The termination of diapause in this species, although occurring regularly over a period from 3 to 22 weeks at a constant temperature of 22 °C, was found to be accelerated significantly by exposing the diapause larvae to optimal periods of chilling at 5 °C. Suboptimal chilling periods, on the other hand, tended to prolong diapause development. The optimal requirements for diapause development were shown to be an initial chilling period of approximately 12 weeks followed by a short interval of 1–3 weeks at a temperature of 22 °C at which morphogenesis could proceed. Diapause development in L. caesar is discussed in the light of the present status of our knowledge concerning the physiological processes prerequisite to diapause termination.It has been found that the duration of diapause varies to a great extent among individual larvae, even though they are of the same parentage and subjected to the same environmental conditions. Differences also occur in the mean duration of diapause in groups of larvae from different females. It appears that these differences in diapause intensity are genetically determined.

1988 ◽  
Vol 119 (1) ◽  
pp. 111-116 ◽  
Author(s):  
G. J. King ◽  
R. Rajamahendran

ABSTRACT Plasma progesterone concentrations were compared in cyclic (n = 12), pregnant (n =12), oestradiol-induced pseudopregnant (n=12) and hysterectomized gilts (n=10) between days 8 and 27 after oestrus. The results were grouped into periods covering days 8–13, 14–20 and 21–27 and analysed by least-squares analysis of variance. Plasma progesterone concentrations were significantly (P<0·001) higher in hysterectomized compared with other groups between days 8 and 13. Progesterone concentrations declined rapidly after day 14 in cyclic females and gradually in the other groups. Throughout the third and fourth weeks the mean progesterone concentrations for hysterectomized animals were consistently higher than for pseudopregnant animals (P<0·05). The pregnant group means were below but not significantly different from the hysterectomized means in both of the last two periods. The greater progesterone concentrations in hysterectomized gilts indicated that secretion is high without any conceptus-produced or -mediated luteotrophin, and corpora lutea in cyclic, pregnant or pseudopregnant gilts may never reach full secretory potential. J. Endocr. (1988) 119, 111–116


1975 ◽  
Vol 80 (3) ◽  
pp. 551-557 ◽  
Author(s):  
H. Adlercreutz ◽  
F. Martin ◽  
M. J. Tikkanen ◽  
M. Pulkkinen

ABSTRACT The excretion of twelve oestrogens in urine, pooled daily from a group of pregnant women, was determined before, during and after ampicillin administration (2 g/day, for 3 days). On the second day of ampicillin administration total oestrogen excretion fell to 67 % of the mean control value, oestriol excretion to 69% and that of the other eleven individual oestrogens to an average of 62 % of the mean control values. In general, on the third day of treatment and on the two post-treatment days this decrease tended to be corrected. The patterns of change in the urinary levels of the individual metabolites provided no clear lead to the basic mechanism of ampicillin impairment of oestrogen excretion. However, as the drug affected all their excretion in more or less the same way as it did that of oestriol, it is possible that ampicillin interferes primarily with their enterohepatic circulation in the mother as has been established with reasonable certainty in the case of oestriol.


PEDIATRICS ◽  
1958 ◽  
Vol 22 (5) ◽  
pp. 1001-1005
Author(s):  

THE 1958 written examination of the American Board of Pediatrics was taken by 540 candidates on January 10. This is a larger number of candidates than in any previous year with the exception of 1953 when 607 physicians took the test. Grades earned by the 540 candidates ranged from a low mark of 27 to a high of 85, a range satisfactorily adequate for differential selection. After considerable study, the decision was reached to place the passing grade at 51.5. On this basis there were 35 examinees or 6.5% who failed and 505 who passed and were notified of their eligibility for oral examination. Pertinent statistics follow: mean, 65.82; mode, 69.51; median, 67.05; first quartile, 59.56; third quartile, 72.51. Readers will note that the mean and the mode are 3.7 points apart and also that the range from the first quartile to the median is 7.5 points whereas the distance from the median to the third quartile is only 5.5 points. These statistics mean that the Committee continues to be successful in producing an examination that is skewed toward the lower grades. Such a distribution makes the test relatively sensitive in the critical range where a decision must be reached regarding passing or failing and relatively insensitive in selecting honor grades. Calculation of the "probable error of estimate" (P.E.m) has yielded a lower figure than in any previous year. This statistic is computed by giving each candidate two grades, one based on his even numbered questions and the other on his odd numbered questions. The degree to which the two sets of grades are in agreement is a measure of the internal consistency of the examination.


Author(s):  
K. H. Hwang ◽  
G. J. Park

In product design and manufacturing, robust design leads to a product that has good quality. Robust design is reviewed in two categories: one is the process and the other is the robustness index. The process means efficient manipulation of the mean response and the variance. The robustness index indicates a measure of insensitiveness with respect to the variation. To improve existing methods, a three-step robust design (TRD) is proposed. The first step is “reduce the variance,” the second is “find multiple candidate designs,” and the third is “select the optimum robust design by using the robustness index,” Furthermore, a new robustness index is introduced in order to accommodate the characteristics of the probability of success in axiomatic design and the Taguchi’s loss function. The new robustness indices are compared with the existing ones. The developed robust design process is verified by examples and the results using the robustness index are compared with those of other indices.


Development ◽  
1991 ◽  
Vol 111 (4) ◽  
pp. 1087-1095 ◽  
Author(s):  
F. Huang ◽  
C. Dambly-Chaudiere ◽  
A. Ghysen

We have examined the origin of a set of precisely located sense organs in the notum and wing of Drosophila, in transformant flies where lacZ is expressed in the progenitor cells of the sense organs (the sensory mother cells) and in their progeny. Here we describe the temporal pattern of appearance and divisions of the sensory mother cells that will form the eleven macrochaetes and the two trichoid sensilla of the notum, and five campaniform sensilla on the wing blade. The complete pattern of sensory mother cells develops in a strict sequence that extends over most of the third larval instar and the first 10 h after puparium formation. The delay between the onset of lacZ expression and the first differentiative division ranges from 30 h, in the case of the earliest mother cells, to 2 h for the latest mother cells. The first division shows a preferential orientation which is also specific for each sensory mother cell. Up to this stage, there is no marked difference between the three types of mechanosensory organs.


2012 ◽  
Vol 5 (2) ◽  
pp. 33
Author(s):  
Endah Fauziningrum

The objective of this research was to find out the effectiveness of using STAD and TMR strategies to teach questions to the third grade of elementary school students. The data of the research were taken in Sompok state elementary school 03 and 04. The research design used was factorial design. It means that the writer had two groups, one was taught by using STAD strategy and the other was taught by using TMR strategy. STAD and TMR strategies had two sub-divisions, students who take English courses and students who do not take English courses. The number of the research sample for each cell was 12 students. There were four time lesson of periods for STAD and TMR classes. To investigate the effectiveness of using STAD and TMR strategies, the writer used F-test formula. The results were: 1) STAD was effective to teach question to students who take English courses. It was showed from the pre-test (10.83) and the post-test (12.75). 2) STAD was effective to teach question to students who do not take English courses. It was shown on the mean of pre-test (8.58) and the post-test (11.25). 3) TMR was effective to teach question to students who take English courses. It was shown on the mean of pre-test (10.67) and the post-test (11.50).  4) TMR was effective to teach question to students who do not take English courses. It was shown on the mean of pre-test (9.83) and post-test (10.42). There was not any interaction between the students who take English courses and who do not and and who were taught by using STAD and TMR atrategies.it showed from the ANOVA result. The result was the interaction between strategies and taking courses variables showed 0.325 with sig 0.571. Since, sig 0.571 > 0.05, then the interaction between strategies and taking courses variables do not effect the students achievement. Keywords:  Comparison; Third Grade Elementary School Students; STAD Strategy; TMR Strategy;the Effectiveness of Using Teaching Strategy 


2012 ◽  
Vol 5 (2) ◽  
pp. 33-54
Author(s):  
Endah Fauziningrum

The objective of this research was to find out the effectiveness of using STAD and TMR strategies to teach questions to the third grade of elementary school students. The data of the research were taken in Sompok state elementary school 03 and 04. The research design used was factorial design. It means that the writer had two groups, one was taught by using STAD strategy and the other was taught by using TMR strategy. STAD and TMR strategies had two sub-divisions, students who take English courses and students who do not take English courses. The number of the research sample for each cell was 12 students. There were four time lesson of periods for STAD and TMR classes. To investigate the effectiveness of using STAD and TMR strategies, the writer used F-test formula. The results were: 1) STAD was effective to teach question to students who take English courses. It was showed from the pre-test (10.83) and the post-test (12.75). 2) STAD was effective to teach question to students who do not take English courses. It was shown on the mean of pre-test (8.58) and the post-test (11.25). 3) TMR was effective to teach question to students who take English courses. It was shown on the mean of pre-test (10.67) and the post-test (11.50).  4) TMR was effective to teach question to students who do not take English courses. It was shown on the mean of pre-test (9.83) and post-test (10.42). There was not any interaction between the students who take English courses and who do not and and who were taught by using STAD and TMR atrategies.it showed from the ANOVA result. The result was the interaction between strategies and taking courses variables showed 0.325 with sig 0.571. Since, sig 0.571 0.05, then the interaction between strategies and taking courses variables do not effect the students achievement. Keywords:  Comparison; Third Grade Elementary School Students; STAD Strategy; TMR Strategy;the Effectiveness of Using Teaching Strategy 


1993 ◽  
Vol 69 (01) ◽  
pp. 035-040 ◽  
Author(s):  
A M H P van den Besselaar ◽  
R M Bertina

SummaryFour thromboplastin reagents were tested by 18 laboratories in Europe, North-America, and Australasia, according to a detailed protocol. One thromboplastin was the International Reference Preparation for ox brain thromboplastin combined with adsorbed bovine plasma (coded OBT/79), and the second was a certified reference material for rabbit brain thromboplastin, plain (coded CRM 149R). The other two thromboplastin reagents were another rabbit plain brain thromboplastin (RP) with a lower ISI than CRM 149R and a rabbit brain thromboplastin combined with adsorbed bovine plasma (RC). Calibration of the latter two reagents was performed according to methods recommended by the World Health Organization (W. H. O.).The purpose of this study was to answer the following questions: 1) Is the calibration of the RC reagent more precise against the bovine/combined (OBT/79) than against the rabbit/plain reagent (CRM 149R)? 2) Is the precision of calibration influenced by the magnitude of the International Sensitivity Index (ISI)?The lowest inter-laboratory variation of ISI was observed in the calibration of the rabbit/plain reagent (RP) against the other rabbit/plain reagent (CRM 149R) (CV 1.6%). The highest interlaboratory variation was obtained in the calibration of rabbit/plain (RP) against bovine/combined (OBT/79) (CV 5.1%). In the calibration of the rabbit/combined (RC) reagent, there was no difference in precision between OBT/79 (CV 4.3%) and CRM 149R (CV 4.2%). Furthermore, there was no significant difference in the precision of the ISI of RC obtained with CRM 149R (ISI = 1.343) and the rabbit/plain (RP) reagent with ISI = 1.14. In conclusion, the calibration of RC could be performed with similar precision with either OBT/79 or CRM 149R, or RP.The mean ISI values calculated with OBT/79 and CRM 149R were practically identical, indicating that there is no bias in the ISI of these reference preparations and that these reference preparations have been stable since their original calibration studies in 1979 and 1987, respectively.International Normalized Ratio (INR) equivalents were calculated for a lyophilized control plasma derived from patients treated with oral anticoagulants. There were small but significant differences in the mean INR equivalents between the bovine and rabbit thromboplastins. There were no differences in the interlaboratory variation of the INR equivalents, when the four thromboplastins were compared.


1979 ◽  
Vol 42 (04) ◽  
pp. 1073-1114 ◽  

SummaryIn collaborative experiments in 199 laboratories, nine commercial thromboplastins, four thromboplastins held by the National Institute for Biological Standards and Control (NIBS & C), London and the British Comparative Thromboplastin were tested on fresh normal and coumarin plasmas, and on three series of freeze-dried plasmas. One of these was made from coumarin plasmas and the other two were prepared from normal plasmas; in each series, one plasma was normal and the other two represented different degrees of coumarin defect.Each thromboplastin was calibrated against NIBS&C rabbit brain 70/178, from the slope of the line joining the origin to the point of intersection of the mean ratios of coumarin/normal prothrombin times when the ratios obtained with the two thromboplastins on the same fresh plasmas were plotted against each other. From previous evidence, the slopes were calculated which would have been obtained against the NIBS&C “research standard” thromboplastin 67/40, and termed the “calibration constant” of each thromboplastin. Values obtained from the freeze-dried coumarin plasmas gave generally similar results to those from fresh plasmas for all thromboplastins, whereas values from the artificial plasmas agreed with those from fresh plasmas only when similar thromboplastins were being compared.Taking into account the slopes of the calibration lines and the variation between laboratories, precision in obtaining a patient’s prothrombin time was similar for all thromboplastins.


1985 ◽  
Vol 54 (04) ◽  
pp. 739-743 ◽  
Author(s):  
Federica Delaini ◽  
Elisabetta Dejana ◽  
Ine Reyers ◽  
Elisa Vicenzi ◽  
Germana De Bellis Vitti ◽  
...  

SummaryWe have investigated the relevance of some laboratory tests of platelet function in predicting conditions of thrombotic tendency. For this purpose, we studied platelet survival, platelet aggregation in response to different stimuli, TxB2 and 6-keto-PGFlα production in serum of rats bearing a nephrotic syndrome induced by adriamycin. These animals show a heavy predisposition to the development of both arterial and venous thrombosis. The mean survival time was normal in nephrotic rats in comparison to controls. As to aggregation tests, a lower aggregating response was found in ADR-treated rats using ADP or collagen as stimulating agents. With arachidonic acid (AA) we observed similar aggregating responses at lower A A concentrations, whereas at higher AA concentrations a significantly lower response was found in nephrotic rats, despite their higher TxB2 production. Also TxB2 and 6-keto-PGFlα levels in serum of nephrotic rats were significantly higher than in controls. No consistent differences were found in PGI2-activity generated by vessels of control or nephrotic rats.These data show that platelet function may appear normal or even impaired in rats with a markedly increased thrombotic tendency. On the other hand, the significance of high TxB2 levels in connection with mechanisms leading to thrombus formation remains a controversial issue.


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