Risk factors for immersion pulmonary edema: hyperoxia does not attenuate pulmonary hypertension associated with cold water-immersed prone exercise at 4.7 ATA

2011 ◽  
Vol 110 (3) ◽  
pp. 610-618 ◽  
Author(s):  
J. A. V. Fraser ◽  
D. F. Peacher ◽  
J. J. Freiberger ◽  
M. J. Natoli ◽  
E. A. Schinazi ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Pulmonary Edema ◽  
Cold Water ◽  
Minute Ventilation ◽  
Water Immersion ◽  
Venous Pressure ◽  
Venous Blood ◽  
Blood Gases ◽  
Cold Water Immersion ◽  
Preventive Strategy

Hyperoxia has been shown to attenuate the increase in pulmonary artery (PA) pressure associated with immersed exercise in thermoneutral water, which could serve as a possible preventive strategy for the development of immersion pulmonary edema (IPE). We tested the hypothesis that the same is true during exercise in cold water. Six healthy volunteers instrumented with arterial and PA catheters were studied during two 16-min exercise trials during prone immersion in cold water (19.9–20.9°C) in normoxia [0.21 atmospheres absolute (ATA)] and hyperoxia (1.75 ATA) at 4.7 ATA. Heart rate (HR), Fick cardiac output (CO), mean arterial pressure (MAP), pulmonary artery pressure (PAP), pulmonary artery wedge pressure (PAWP), central venous pressure (CVP), arterial and venous blood gases, and ventilatory parameters were measured both early (E, 5–6 min) and late (L, 15–16 min) in exercise. During exercise at an average oxygen consumption rate (V̇o2) of 2.38 ml·kg−1·min−1, CO, CVP, and pulmonary vascular resistance were not affected by inspired Po2or exercise duration. Minute ventilation (V̇e), alveolar ventilation (V̇a), and ventilation frequency ( f) were significantly lower in hyperoxia compared with normoxia (mean ± SD: V̇e 58.8 ± 8.0 vs. 65.1 ± 9.2, P = 0.003; V̇a 40.2 ± 5.4 vs. 44.2 ± 9.0, P = 0.01; f 25.4 ± 5.4 vs. 27.2 ± 4.2, P = 0.04). Mixed venous pH was lower in hyperoxia compared with normoxia (7.17 ± 0.07 vs. 7.20 ± 0.07), and this result was significant early in exercise ( P = 0.002). There was no difference in mean PAP (MPAP: 28.28 ± 8.1 and 29.09 ± 14.3 mmHg) or PAWP (18.0 ± 7.6 and 18.7 ± 8.7 mmHg) between normoxia and hyperoxia, respectively. PAWP decreased from early to late exercise in hyperoxia ( P = 0.002). These results suggest that the increase in pulmonary vascular pressures associated with cold water immersion is not attenuated with hyperoxia.

Physiological Responses to Cold Water Immersion Following Cycling in the Heat

2008 ◽  
Vol 3 (3) ◽  
pp. 331-346 ◽  
Author(s):  
Shona L. Halson ◽  
Marc J. Quod ◽  
David T. Martin ◽  
Andrew S. Gardner ◽  
Tammie R. Ebert ◽  
...  
Keyword(s):  
Heart Rate ◽  
Inflammatory Responses ◽  
Cold Water ◽  
Water Immersion ◽  
Scientific Information ◽  
Venous Blood ◽  
Blood Gases ◽  
Cold Water Immersion ◽  
Blood Samples ◽  
Reactive Protein

Cold water immersion (CWI) has become a popular means of enhancing recovery from various forms of exercise. However, there is minimal scientific information on the physiological effects of CWI following cycling in the heat.Purpose:To examine the safety and acute thermoregulatory, cardiovascular, metabolic, endocrine, and inflammatory responses to CWI following cycling in the heat.Methods:Eleven male endurance trained cyclists completed two simulated ~40-min time trials at 34.3 ± 1.1°C. All subjects completed both a CWI trial (11.5°C for 60 s repeated three times) and a control condition (CONT; passive recovery in 24.2 ± 1.8°C) in a randomized cross-over design. Capillary blood samples were assayed for lactate, glucose, pH, and blood gases. Venous blood samples were assayed for catecholamines, cortisol, testosterone, creatine kinase, C-reactive protein, IL-6, and IGF-1 on 7 of the 11 subjects. Heart rate (HR), rectal (Tre), and skin temperatures (Tsk) were measured throughout recovery.Results:CWI elicited a significantly lower HR (CWI: Δ116 ± 9 bpm vs. CONT: Δ106 ± 4 bpm; P = .02), Tre (CWI: Δ1.99 ± 0.50°C vs. CONT: Δ1.49 ± 0.50°C; P = .01) and Tsk. However, all other measures were not significantly different between conditions. All participants subjectively reported enhanced sensations of recovery following CWI.Conclusion:CWI did not result in hypothermia and can be considered safe following high intensity cycling in the heat, using the above protocol. CWI significantly reduced heart rate and core temperature; however, all other metabolic and endocrine markers were not affected by CWI.

Muscle glycogen utilization during shivering thermogenesis in humans

1988 ◽  
Vol 65 (5) ◽  
pp. 2046-2050 ◽  
Author(s):  
L. Martineau ◽  
I. Jacobs
Keyword(s):  
Skeletal Muscle ◽  
Muscle Glycogen ◽  
Cold Water ◽  
Vastus Lateralis ◽  
Water Immersion ◽  
Venous Blood ◽  
Cold Water Immersion ◽  
Vastus Lateralis Muscle ◽  
Glucose Levels ◽  
Shivering Thermogenesis

The purpose of the present study was to clarify the importance of skeletal muscle glycogen as a fuel for shivering thermogenesis in humans during cold-water immersion. Fourteen seminude subjects were immersed to the shoulders in 18 degrees C water for 90 min or until rectal temperature (Tre) decreased to 35.5 degrees C. Biopsies from the vastus lateralis muscle and venous blood samples were obtained before and immediately after the immersion. Metabolic rate increased during the immersion to 3.5 +/- 0.3 (SE) times resting values, whereas Tre decreased by 0.9 degrees C to approximately 35.8 degrees C at the end of the immersion. Intramuscular glycogen concentration in the vastus lateralis decreased from 410 +/- 15 to 332 +/- 18 mmol glucose/kg dry muscle, with each subject showing a decrease (P less than 0.001). Plasma volume decreased (P less than 0.001) markedly during the immersion (-24 +/- 1%). After correcting for this decrease, blood lactate and plasma glycerol levels increased by 60 (P less than 0.05) and 38% (P less than 0.01), respectively, whereas plasma glucose levels were reduced by 20% after the immersion (P less than 0.001). The mean expiratory exchange ratio showed a biphasic pattern, increasing initially during the first 30 min of the immersion from 0.80 +/- 0.06 to 0.85 +/- 0.05 (P less than 0.01) and decreasing thereafter toward basal values. The results demonstrate clearly that intramuscular glycogen reserves are used as a metabolic substrate to fuel intensive thermogenic shivering activity of human skeletal muscle.

scholarly journals The Impact of Moderate Physical Exercise on the Rheological and Biochemical Properties of Blood in Osteoarthritis Patients Who Are Regular Winter Swimmers

2021 ◽  
Vol 69 (1) ◽  
pp. 31-37
Author(s):  
Małgorzata Strzelczyk ◽  
Aneta Teległów ◽  
Jakub Marchewka ◽  
Bartłomiej Ptaszek ◽  
Anna Marchewka
Keyword(s):  
Physical Exercise ◽  
Cold Water ◽  
Water Immersion ◽  
Venous Blood ◽  
Exercise Program ◽  
Blood Parameters ◽  
Cold Water Immersion ◽  
Biochemical Properties ◽  
Rheological Parameters ◽  
The Impact

The aim of this study was to assess the influence of moderate physical exercise on selected blood parameters in regular winter swimmers who suffer from osteoarthritis. The study covered a period of 6 months, from November to April, and was carried out on 17 women and 22 men. The participants were divided into 4 groups: Female CWI – women who only immersed themselves in cold water, Female CWI + PE – women who exercised in addition to water immersion, Male CWI – men who only immersed themselves in cold water, and Male CWI + PE – men, who exercised in addition to water immersion. Venous blood was collected twice, before and after the exercise program. A statistically significant decrease in fibrinogen, plasma viscosity, T ½ , and AMP was observed in the blood of people who did not take part in the physical exercise program while a significant decrease in cortisol levels was observed in the people who participated in the exercise program in addition to cold water immersion. In terms of rheological parameters, a significant increase in the elongation index (EI) of erythrocytes from shear stress 2.19 Pa in all groups was observed. There were no statistically significant changes in AI in all groups. Physical activity has an influence on the blood parameters of elderly winter swimmers suffering from osteoarthritis.

scholarly journals Cold water immersion enhances recovery of submaximal muscle function after resistance exercise

2014 ◽  
Vol 307 (8) ◽  
pp. R998-R1008 ◽  
Author(s):  
Llion A. Roberts ◽  
Kazunori Nosaka ◽  
Jeff S. Coombes ◽  
Jonathan M. Peake
Keyword(s):  
Resistance Exercise ◽  
High Intensity ◽  
Muscle Function ◽  
Cold Water ◽  
Water Immersion ◽  
Venous Blood ◽  
Cold Water Immersion ◽  
Active Recovery ◽  
Physically Active ◽  
Training Adaptations

We investigated the effect of cold water immersion (CWI) on the recovery of muscle function and physiological responses after high-intensity resistance exercise. Using a randomized, cross-over design, 10 physically active men performed high-intensity resistance exercise followed by one of two recovery interventions: 1) 10 min of CWI at 10°C or 2) 10 min of active recovery (low-intensity cycling). After the recovery interventions, maximal muscle function was assessed after 2 and 4 h by measuring jump height and isometric squat strength. Submaximal muscle function was assessed after 6 h by measuring the average load lifted during 6 sets of 10 squats at 80% of 1 repetition maximum. Intramuscular temperature (1 cm) was also recorded, and venous blood samples were analyzed for markers of metabolism, vasoconstriction, and muscle damage. CWI did not enhance recovery of maximal muscle function. However, during the final three sets of the submaximal muscle function test, participants lifted a greater load ( P < 0.05, Cohen's effect size: 1.3, 38%) after CWI compared with active recovery. During CWI, muscle temperature decreased ∼7°C below postexercise values and remained below preexercise values for another 35 min. Venous blood O2 saturation decreased below preexercise values for 1.5 h after CWI. Serum endothelin-1 concentration did not change after CWI, whereas it decreased after active recovery. Plasma myoglobin concentration was lower, whereas plasma IL-6 concentration was higher after CWI compared with active recovery. These results suggest that CWI after resistance exercise allows athletes to complete more work during subsequent training sessions, which could enhance long-term training adaptations.

The Effect of Clothing on the initial Responses to Cold Water Immersion in man

1990 ◽  
Vol 76 (2) ◽  
pp. 89-95
Author(s):  
M. J. Tipton ◽  
D. A. Stubbs ◽  
D. H. Elliott
Keyword(s):  
Protective Clothing ◽  
Cold Shock ◽  
Cold Water ◽  
Minute Ventilation ◽  
Water Immersion ◽  
Cold Water Immersion ◽  
List Type ◽  
Healthy Male ◽  
Cold Shock Response ◽  
Shock Response

AbstractThe protection provided by three clothing assemblies against the cold shock response was investigated. Nine healthy male volunteers each undertook three two minute head-out immersions into stirred water at 10°C. The subjects wore a different clothing assembly for each immersion, these were: (a)Swimming trunks only;(b)Conventional clothing (equivalent to RN No 8s);(c)Conventional clothing plus windproof/showerproof clothing (RN foul-weather clothing Mk III).The cardiac, ventilatory and thermal responses of the subjects were examined before and during the immersions.No significant differences were found between the magnitude of the responses recorded on immersion when conventional clothing or foul-weather clothing were worn. Mean skin temperature was lower (P<0.05) and respiratory frequency and minute ventilation were higher (P<0.05) on immersion in swimming trunks compared to the other two conditions.It is concluded that when policies for the use of immersion protective clothing are being formulated, consideration should be given to all of the potentially hazardous responses associated with cold water immersion.

Patient Involvement in Treatment Decision Making Can Help or Hinder Placebo Analgesia

2014 ◽  
Vol 222 (3) ◽  
pp. 165-170 ◽  
Author(s):  
Andrew L. Geers ◽  
Jason P. Rose ◽  
Stephanie L. Fowler ◽  
Jill A. Brown
Keyword(s):  
Patient Involvement ◽  
Cold Water ◽  
Prior Experience ◽  
Water Immersion ◽  
Treatment Decision ◽  
Cold Water Immersion ◽  
Not Given ◽  
Placebo Analgesia ◽  
Treatment Decision Making ◽  
Immersion Experience

Experiments have found that choosing between placebo analgesics can reduce pain more than being assigned a placebo analgesic. Because earlier research has shown prior experience moderates choice effects in other contexts, we tested whether prior experience with a pain stimulus moderates this placebo-choice association. Before a cold water pain task, participants were either told that an inert cream would reduce their pain or they were not told this information. Additionally, participants chose between one of two inert creams for the task or they were not given choice. Importantly, we also measured prior experience with cold water immersion. Individuals with prior cold water immersion experience tended to display greater placebo analgesia when given choice, whereas participants without this experience tended to display greater placebo analgesia without choice. Prior stimulus experience appears to moderate the effect of choice on placebo analgesia.

Thermoregulatory responses to cold water at different times of day

1999 ◽  
Vol 87 (1) ◽  
pp. 243-246 ◽  
Author(s):  
John W. Castellani ◽  
Andrew J. Young ◽  
James E. Kain ◽  
Michael N. Sawka
Keyword(s):  
Cold Water ◽  
Water Immersion ◽  
Early Morning ◽  
Cold Water Immersion ◽  
Time Of Day ◽  
Mean Skin Temperature ◽  
Mean Body Temperature ◽  
Metabolic Heat ◽  
Body Temperature Change ◽  
The Mean

This study examined how time of day affects thermoregulation during cold-water immersion (CWI). It was hypothesized that the shivering and vasoconstrictor responses to CWI would differ at 0700 vs. 1500 because of lower initial core temperatures (Tcore) at 0700. Nine men were immersed (20°C, 2 h) at 0700 and 1500 on 2 days. No differences ( P > 0.05) between times were observed for metabolic heat production (M˙, 150 W ⋅ m−2), heat flow (250 W ⋅ m−2), mean skin temperature (T sk, 21°C), and the mean body temperature-change in M˙(ΔM˙) relationship. Rectal temperature (Tre) was higher ( P < 0.05) before (Δ = 0.4°C) and throughout CWI during 1500. The change in Tre was greater ( P < 0.05) at 1500 (−1.4°C) vs. 0700 (−1.2°C), likely because of the higher Tre-T skgradient (0.3°C) at 1500. These data indicate that shivering and vasoconstriction are not affected by time of day. These observations raise the possibility that CWI may increase the risk of hypothermia in the early morning because of a lower initial Tcore.

scholarly journals Recovery strategies implemented by sport support staff of elite rugby players in South Africa

2009 ◽  
Vol 65 (1) ◽  
Author(s):  
D.V. Van Wyk ◽  
M.I. Lambert
Keyword(s):  
Cold Water ◽  
Water Immersion ◽  
Total Duration ◽  
Cold Water Immersion ◽  
Support Staff ◽  
Medical Support ◽  
Cross Sectional ◽  
Study Results ◽  
Recovery Strategies ◽  
Rugby Players

Objective: The main aim of this study was to determine strategies used toaccelerate recovery of elite rugby players after training and matches, asused by medical support staff of rugby teams in South A frica. A  secondaryaim was to focus on specifics of implementing ice/cold water immersion asrecovery strategy. Design: A  Questionnaire-based cross sectional descriptive survey was used.Setting and Participants: Most (n=58) of the medical support staff ofrugby teams (doctors, physiotherapists, biokineticists and fitness trainers)who attended the inaugural Rugby Medical A ssociation conference linked to the South A frican Sports MedicineA ssociation Conference in Pretoria (14-16th November, 2007) participated in the study. Results: Recovery strategies were utilized mostly after matches. Stretching and ice/cold water immersion were utilized the most (83%). More biokineticists and fitness trainers advocated the usage of stretching than their counter-parts (medical doctors and physiotherapists). Ice/Cold water immersion and A ctive Recovery were the top two ratedstrategies. A  summary of the details around implementation of ice/cold water therapy is shown (mean) as utilized bythe subjects: (i) The time to immersion after matches was 12±9 min; (ii) The total duration of one immersion sessionwas 6±6 min; (iii) 3 immersion sessions per average training week was utilized by subjects; (iv) The average water temperature was 10±3 ºC.; (v) Ice cubes were used most frequently to cool water for immersion sessions, and(vi) plastic drums were mostly used as the container for water. Conclusion: In this survey the representative group of support staff provided insight to which strategies are utilizedin South A frican elite rugby teams to accelerate recovery of players after training and/or matches.

scholarly journals Cold-water immersion following sprint interval training does not alter endurance signaling pathways or training adaptations in human skeletal muscle

2017 ◽  
Vol 313 (4) ◽  
pp. R372-R384 ◽  
Author(s):  
James R. Broatch ◽  
Aaron Petersen ◽  
David J. Bishop
Keyword(s):  
Mitochondrial Biogenesis ◽  
Molecular Mechanisms ◽  
Cold Water ◽  
P53 Protein ◽  
Water Immersion ◽  
Interval Training ◽  
Cold Water Immersion ◽  
Peroxisome Proliferator ◽  
Sprint Interval Training ◽  
Single Session

We investigated the underlying molecular mechanisms by which postexercise cold-water immersion (CWI) may alter key markers of mitochondrial biogenesis following both a single session and 6 wk of sprint interval training (SIT). Nineteen men performed a single SIT session, followed by one of two 15-min recovery conditions: cold-water immersion (10°C) or a passive room temperature control (23°C). Sixteen of these participants also completed 6 wk of SIT, each session followed immediately by their designated recovery condition. Four muscle biopsies were obtained in total, three during the single SIT session (preexercise, postrecovery, and 3 h postrecovery) and one 48 h after the last SIT session. After a single SIT session, phosphorylated (p-)AMPK, p-p38 MAPK, p-p53, and peroxisome proliferator-activated receptor-γ coactivator-1α ( PGC-1α) mRNA were all increased ( P < 0.05). Postexercise CWI had no effect on these responses. Consistent with the lack of a response after a single session, regular postexercise CWI had no effect on PGC-1α or p53 protein content. Six weeks of SIT increased peak aerobic power, maximal oxygen consumption, maximal uncoupled respiration (complexes I and II), and 2-km time trial performance ( P < 0.05). However, regular CWI had no effect on changes in these markers, consistent with the lack of response in the markers of mitochondrial biogenesis. Although these observations suggest that CWI is not detrimental to endurance adaptations following 6 wk of SIT, they question whether postexercise CWI is an effective strategy to promote mitochondrial biogenesis and improvements in endurance performance.

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