scholarly journals Antiobesity Activities of Methanolic Extracts ofAmaranthus dubius,Cucurbita pepo, andVigna unguiculatain Progesterone-Induced Obese Mice

2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Kathryn Wanjiku Nderitu ◽  
Njagi Shadrack Mwenda ◽  
Ndegwa John Macharia ◽  
Stephen Super Barasa ◽  
Mathew Piero Ngugi
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Cucurbita Pepo ◽  
Profile Analysis ◽  
Negative Control ◽  
Control Group ◽  
Obese Mice ◽  
Leaf Extracts ◽  
Lipid Parameter ◽  
Significant Difference

Amaranthus dubius,Vigna unguiculata,andCucurbita pepoare traditionally used to manage obesity in Kenya but lack scientific validation to support their use. The aim of this study was to determine the antiobesity activity of methanolic leaf extracts of these plants in progesterone-induced obese mice. The activity of the methanolic leaf extracts was orally bioscreened in progesterone-induced obese mice at 200 mg/kg/bw and 400 mg/kg/bw. Body mass index was calculated once per week for four weeks and blood samples were obtained at the end of the experiment for lipid profile analysis. Antiobesity activities of the extracts were compared with the controls. Leaf extracts ofA. dubius,C. pepo,andV. unguiculata,at dose concentrations of 200 mg/kgbw and 400 mg/kgbw, showed significant effects on body mass index (p<0.05). There was no significant difference between the three extracts on lipid parameter profiles (p>0.05). The present study showed high food intake in the negative control group as compared with normal control, positive control, and treatment groups. These extracts contained various phytochemicals such as saponins, flavonoids, alkaloids, and steroids and therefore validate use of aforementioned plants in the suppression of obesity and their use for management of obesity is recommended.

Children Exposed or Unexposed to Human Immunodeficiency Virus: Weight, Height, and Body Mass Index During the First 5 Years of Life—A Danish Nationwide Cohort

2019 ◽  
Vol 70 (10) ◽  
pp. 2168-2177
Author(s):  
Ellen Moseholm ◽  
Marie Helleberg ◽  
Håkon Sandholdt ◽  
Terese L Katzenstein ◽  
Merete Storgaard ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Well Being ◽  
World Health ◽  
Control Group ◽  
Growth Chart ◽  
Significant Difference ◽  
Negative Effect ◽  
Z Scores ◽  
Health Organization

Abstract Background Exposures to human immunodeficiency (HIV) and antiretroviral therapy in utero may have adverse effects on infant growth. Among children born in Denmark and aged 0–5 years, we aimed to compare anthropometric outcomes in HIV-exposed but uninfected (HEU) children with those in children not exposed to HIV. Methods In a nationwide register-based study we included all singleton HEU children born in Denmark in 2000–2016. HEU children were individually matched by child sex, parity, and maternal place of birth to 5 singleton controls born to mothers without HIV. Weight-for-age z (WAZ) scores, length-for-age z (LAZ) scores, and weight-for-length or body mass index–for–age z scores were generated according to the World Health Organization standards and the Fenton growth chart for premature infants. Differences in mean z scores were analyzed using linear mixed models, both univariate and adjusted for social and maternal factors. Results In total, 485 HEU children and 2495 HIV-unexposed controls were included. Compared with controls, HEU children were smaller at birth, with an adjusted difference in mean WAZ and LAZ scores of −0.29 (95% confidence interval [CI], −.46 to −.12) and −0.51 (95% CI, −.71 to −.31), respectively (both P ≤ .001). Over time, there was a trend toward increasing WAZ and LAZ scores in HEU children, and there was no significant difference in adjusted WAZ scores after age 14 days (−0.13 [95% CI, −.27 to .01]; P = .07) and LAZ scores after age 6 months (−0.15 [95% CI, −.32 to .02]; P = .08). Conclusion Compared with a matched control group, HEU children were smaller at birth, but this difference decreased with time and is not considered to have a negative effect on the health and well-being of HEU children during early childhood.

scholarly journals The Effects of Cardiovascular Exercises on Body Mass Index and Vital Capacity among Students of Sargodha University

2020 ◽  
Vol V (III) ◽  
pp. 358-364
Author(s):  
Yassar Iqbal ◽  
Zubia Savila ◽  
Muhammad Badar Habib
Keyword(s):  
Body Mass Index ◽  
University Students ◽  
Body Mass ◽  
Vital Capacity ◽  
Control Group ◽  
P Value ◽  
Daily Routine ◽  
Cardiovascular Exercise ◽  
Significant Difference ◽  
Experimental Group

This research was designed to evaluate the effect of cardiovascular exercises on body mass index (BMI) and vital capacity (VC) among student aged between 21-27 years (M � SD 22.3� 3.05). The experimental research study was applied to 54 University students of Sargodha. Data were analyzed by using SPSS version 24.0. P-value ? 0.05 was considered significant. The result showed that the average BMI of the control group and experimental groups was 20.73�3.02 vs 21.51�3.21. The effectiveness of cardiovascular exercise on Vital capacity on Pre and post-test of the experimental group was -56.91272 � 22.03192 with a pvalue of 0.000, which was showed there was a highly significant improvement in vital capacity of students and compare with the control group. It was concluded that body masses index and vital capacity is significantly improved in university students of the experimental group as a result of 10 weeks of the cardiovascular exercise training program. Conclude that there is a significant difference between the effects of cardiovascular exercise and daily routine sports activities on BMI.

scholarly journals Association between Body Mass Index and Migraine: A Survey of Adult Population in China

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Qingqing Huang ◽  
Xiping Liang ◽  
Shiqiang Wang ◽  
Xiaosong Mu
Keyword(s):  
Body Mass Index ◽  
Chronic Migraine ◽  
Body Mass ◽  
Adult Population ◽  
Primary Headache ◽  
Control Group ◽  
Morbidly Obese ◽  
Significant Difference ◽  
Headache Onset ◽  
Headache Patients

Both migraine and obesity are prevalent disorders in the general population, which are characterized by disability and impaired quality of life. Although so many researches had studied the association between migraine and obesity, there are still no full knowledge of the relationship between body mass index (BMI) and migraine, especially chronic migraine (CM). In this study, we analyzed a previous epidemiological survey data of primary headache patients in Chongqing, which surveyed consecutive neurological outpatients through face-to-face interview with physicians using a headache questionnaire. 166 episodic migraine (EM) patients and 134 chronic migraine (CM) patients were included in the study out of 1327 primary headache patients. And 200 healthy adults from the physical examination center were included as a control group. Finally, we found that the patients with migraine (EM and CM) were more likely to be overweight, obese, or morbidly obese compared to those in the healthy group. Significant difference was found between BMI and frequency of migraine attacks but not severity or duration of headache onset. And no significant difference was found in severity and duration of headache onset between episodic and chronic migraine among different BMI classifications. Such may update our knowledge about the clinical features of migraine and BMI, revealing that the frequency of attacks may be associated with being overweight, obese, or morbidly obese in patients with migraine and that the extent of being overweight, obese, or morbidly obese in CM patients was lower than that in EM patients.

scholarly journals EVALUATION OF GALECTIN-3 LEVELS IN OBESE ADOLESCENTS

2019 ◽  
Vol 3 (3) ◽  
Author(s):  
Hüseyin Dag ◽  
Nevin Cetin Dag ◽  
Emine Turkkan ◽  
Ebru Misirli Ozdemir ◽  
Okan Dikker
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Obese Adolescent ◽  
Adolescent Group ◽  
Obese Adolescents ◽  
Significant Difference ◽  
Galectin 3 ◽  
Healthy Control

Background: Galectin-3 is a member of the family of soluble beta-galactoside binding lectins, which is involved in inflammation, cell differentiation, adhesion, proliferation, angiogenesis and cancer cell invasion. Increased galectin-3 levels in obese patients have been shown in previous studies. In our study; we aimed to investigate the galectin-3 levels in obese adolescents for the first time in the literature. Materials and methods: A total of 85 adolescent patients who were admitted to our pediatrics outpatient clinic between December 19th of 2018 and January 31st of 2019 were included in our study. Among those patients 52 were obese and 33 were normal-weighted. Adolescents having body mass index (BMI) 95% percentile and above according to their age and sex were defined as obese. Enzyme-Linked Immunosorbent Assay kit was used for the measurement of galectin-3 in serum. Laboratory tests (Galectin-3, HbA1c, glucose, insulin, HOMA-IR), sex, age and BMI were statistically compared between groups. Results: We found no statistically significant difference in terms of gender distribution rates, age, glucose or galectin-3 levels among obese adolescent and healthy control groups (p> 0.05). The BMI, HbA1c, HOMA-IR and insulin levels of the obese adolescent group were found to be significantly higher than the healthy control group (p <0.05). We found no statistically significant correlation between galectin-3 levels and other parameters in obese adolescent group (p> 0.05). Conclusion: In our study, we did not find any relationship between serum galectin-3 levels and obesity in adolescents. We believe that the effects of galectin-3 levels on obesity in adolescents should be more clearly explained by further investigations, which also measures other biomarkers of the mechanism of action. Keywords: Galectin-3, obesity, adolescent List of abbreviations: BMI: Body-Mass Index, CV: Variation coefficient, ELISA: Enzyme linked immunoassay, HOMA-IR: Homeostatic model of assessment-insulin resistance, IL: Interleukin, r: Correlation coefficient, SD: Standard deviation.

scholarly journals DO DAILY STEP COUNTS DURING THE PANDEMIC AFFECT THE BODY COMPOSITION AND MENTAL WELL-BEING OF UNIVERSITY STUDENTS?

2021 ◽  
Vol 7 (3) ◽  
Author(s):  
Nazlı Yanar ◽  
Melek Güler
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Well Being ◽  
The Body ◽  
Control Group ◽  
Waist Hip Ratio ◽  
Significant Difference ◽  
Post Test ◽  
Mental Well Being ◽  
Experimental Group

This study aims to determine whether the number of daily steps is effective in the body composition and mental well-being of university students during the COVID-19 pandemic. The research group of the study consisted of 40 volunteer students studying at the Faculty of Sport Sciences by being randomly assigned to the experimental (n:20) and control (n:20) groups. The research is in the experimental model with a pre-test/post-test control group. As a data collection tool in the study, the 'Warwick-Edinburgh Mental Well-Being Scale' was used to determine the personal information form and mental well-being. The obtained data were analysed in the Jamovi 1.8.2 statistical software program with a 95% reliability interval and 5% margin of error. In the analysis of the data, percentage (%), frequency (f), and mean (x̄) values were used in the descriptive data, Paired Samples t-test was used in the pre-test/post-test comparison, and Multinomial Regression analysis was used in the relational analysis. According to the findings of the study, 75% of the students in the experimental group and 70% of the students in the control group were in the normal weight class according to the body mass index classification. According to waist-hip ratio classification, 85% of the experimental group and 70% of the control group were in the group that did not have cardiovascular disease risk. After two months of application, the daily average number of steps of the experimental group (12.5751898.1) and the daily average number of steps of the control group were determined as (5381.272026.2). While there was a statistically significant difference in the pre-test/post-test body mass index averages of the experimental group who were asked to take at least 10,000 steps per day (p0.05), although there was an increase in the mean waist-hip ratio and mental well-being, there was no statistically significant difference (p0.05). It was determined that the step average had a statistically significant effect on the experimental group according to the body mass index classification (p0.05). As a result, while taking at least 10,000 steps per day was effective in the body mass index of the students, it was not so in the waist-hip ratio and mental well-being. In this context, physical activity, and especially walking, can be recommended at the point of protecting health. <p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/edu_01/0881/a.php" alt="Hit counter" /></p>

scholarly journals Effect of cold water immersion on muscle damage indexes after simulated soccer training in young soccer players

2020 ◽  
Vol 12 (1) ◽  
pp. 236-241
Author(s):  
Saman Khakpoor Roonkiani ◽  
Mohsen Ebrahimi ◽  
Ali Shamsi Majelan
Keyword(s):  
Body Mass Index ◽  
Muscle Damage ◽  
Body Mass ◽  
Cold Water ◽  
Water Immersion ◽  
Cold Water Immersion ◽  
Soccer Players ◽  
Control Group ◽  
Significant Difference ◽  
Soccer Training

Summary Study aim: To investigate the effect of cold water immersion (CWI) on muscle damage indexes after simulated soccer activity in young soccer players. Material and methods: Eighteen professional male soccer players were randomly divided into two groups: CWI (n = 10, age 19.3 ± 0.5, body mass index 22.2 ± 1.3) and control (n = 8, age 19.4 ± 0.8, body mass index 21.7 ± 1.5). Both groups performed a simulated 90-minute soccer-specific aerobic field test (SAFT90). Then, the CWI group subjects immersed themselves for 10 minutes in 8°C water, while the control group subjects sat passively for the same time period. Blood samples were taken before, immediately after, 10 minutes, 24 hours and 48 hours after the training session in a fasted state. Blood lactate, creatine kinase (CK) and lactate dehydrogenase (LDH) enzyme levels were measured. Results: Lactate, CK and LDH levels increased significantly after training (p < 0.001). There were significant interactions between groups and subsequent measurements for CK (p = 0.0012) and LDH (p = 0.0471). There was no significant difference in lactate level between the two groups at any aforementioned time. Conclusion: It seems that CWI after simulated 90-minute soccer training can reduce the values of muscle damage indexes in soccer players.

scholarly journals Effect of Nutritional Therapy on Body Mass Index of Cancer Patients- A Pilot Study

2021 ◽  
Author(s):  
S shanthi ◽  
. Shambhavi
Keyword(s):  
Body Mass Index ◽  
Nutritional Status ◽  
Body Mass ◽  
Nutritional Therapy ◽  
World Health ◽  
Control Group ◽  
Significant Difference ◽  
Post Test ◽  
And Control ◽  
Test Level

Introduction: Nutritional issues are typically encountered throughout the treatment of cancer. Cancer cachexia is usually recognised as not only reduced bodily function and quality of life, but also poor positive outcome in patients. Naturally, Body Mass Index (BMI) is frequently used for determining nutritional status of a patient. Intervening nutritional problems of the patient leads to better prognosis. It is necessary to identify patients at-risk earlier and provide effective nutritional interventions. Aim: To determine the level of BMI and evaluate the effect of nutritional therapy on BMI and find its association with demographic characteristics. Materials and Methods: This was a quasi-experimental interventional trial conducted among 100 patients admitted in the hospital with a diagnosis of head, neck and breast cancers. Parameters assessed were baseline proforma, weight and height which were measured and BMI was calculated (BMI=kg/m2 in which kg is a individuals weight in kilograms and m2 is their height in meters squared) and classified as per World Health Organisation (WHO) guidelines. Results: Before nutritional intervention 20% and 26% of patients were underweight in the experimental and control group respectively, whereas after 21 days 18% in experimental and 32% in control were underweight. Z score for post-test level of BMI in the experimental and control group were 2.125 and 2.34, respectively is greater than the tabulated value (Z=1.96 at p-value=0.05 level of significance), hence there was a significant difference between post-test level of BMI in the experimental and control group. High protein high caloric whole food was significant. Conclusion: Investigators concluded from the present study that nutrition therapy can help to maintain or improve the nutritional status among patients on cancer treatment.

scholarly journals Higher Body Mass Index Is Associated with Subjective Olfactory Dysfunction

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Z. M. Patel ◽  
J. M. DelGaudio ◽  
S. K. Wise
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Feeding Habits ◽  
Tertiary Care ◽  
Olfactory Dysfunction ◽  
Control Group ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Olfactory Loss ◽  
Significant Difference

Background. Morbidly obese patients demonstrate altered olfactory acuity. There has been no study directly assessing Body Mass Index (BMI) in patients with olfactory dysfunction. Our purpose was to compare BMI in a group of patients with subjective olfactory dysfunction to those without subjective olfactory complaints.Methods. Retrospective matched case-control study. Sixty patients who presented to a tertiary care otolaryngology center with subjective smell dysfunction over one year were identified. Neoplastic and obstructive etiologies were excluded. Demographics, BMI, and smoking status were reviewed. Sixty age, gender, and race matched control patients were selected for comparison. Chi-square testing was used.Results. 48 out of 60 patients (80%) in the olfactory dysfunction group fell into the overweight or obese categories, compared to 36 out of 60 patients (60%) in the control group. There was a statistically significant difference between the olfactory dysfunction and control groups for this stratified BMI(p= 0.0168).  Conclusion. This study suggests high BMI is associated with olfactory dysfunction. Prospective clinical research should examine this further to determine if increasing BMI may be a risk factor in olfactory loss and to elucidate what role olfactory loss may play in diet and feeding habits of obese patients.

scholarly journals Identifying Factors That Contribute to Adolescent Bony Stress Injury in Secondary School Athletes: A Comparative Analysis With a Healthy Athletic Control Group

2019 ◽  
Vol 11 (4) ◽  
pp. 375-379 ◽  
Author(s):  
Eric D. Nussbaum ◽  
Jaynie Bjornaraa ◽  
Charles J. Gatt
Keyword(s):  
High School ◽  
Body Mass Index ◽  
Body Mass ◽  
Weight Training ◽  
Control Group ◽  
Shin Splints ◽  
Dairy Intake ◽  
Significant Difference ◽  
History Of ◽  
And Control

Background:Bony stress injuries (BSIs) are common among adolescents involved in high school sports. A better understanding of factors that contribute to adolescent BSI is needed to target preventative measures.Hypothesis:Individuals who suffer a BSI will demonstrate significant differences in training methods, sleep, diet, and history of injury compared with a healthy, noninjured control group.Study Design:Descriptive epidemiologic study.Methods:Data from the National High School Stress Fracture Registry (NHSSFR), an internet-based adolescent BSI survey, were used to identify variables reported with adolescent (13-18 years of age) BSI. These findings were compared with a survey of 100 (50 males, 50 females) healthy athletic controls to identify significant differences between healthy adolescents and those with BSI.Results:A total of 346 stress fractures were reported in 314 (206 females, 108 males) athletes within the NHSSFR. Comparison with healthy control participants demonstrated multiple significant findings. In particular, body mass index was significantly lower for patients with BSI injury compared with controls ( P < 0.001). Patients slept significantly less than the control group (7.2 vs 7.95 hours; F = 34.41; P < 0.001). Females also slept significantly less hours than males (7.2 vs 7.63 hours; F = 11.02; P < 0.001). Fifty-eight percent of those who reported a BSI did not engage in any weight training. Those with a BSI had significantly higher average stress ratings than control participants (1.67 vs 1.42; P < 0.001), and females also rated their stress levels significantly higher than males (1.8 vs 1.38; P < 0.001). A significant difference between patients with any BSI and control participants existed for history of “shin splints” (Pearson χ2= 28.31; P < 0.001), and females also expressed having shin pain lasting for longer than 4 weeks (Pearson χ2= 8.12; P < 0.001) and more often (Pearson χ2= 5.84; P = 0.02) than males. There was also a significant difference between patients with BSI and control subjects regarding dairy intake (2.25 vs 2.69; F = 6.43; P = 0.01).Conclusion:Findings revealed significant differences between those who reported a BSI relative to healthy athletic adolescents. These differences included body mass index, prior history of shin splints, involvement in weight training, amount of sleep, daily stress, and dairy intake. Preventive measures should be developed to address these areas to reduce the incidence of BSIs in the adolescent population.

scholarly journals Appraisal of A1c% level in healthy Sudanese pregnant women in reference to body mass index

2019 ◽  
Vol 8 (5) ◽  
pp. 1835
Author(s):  
Abdelgadir Ali Elmugadam ◽  
Marwan Ismail ◽  
Abdelgadir Eltom
Keyword(s):  
Body Mass Index ◽  
Pregnant Women ◽  
Body Mass ◽  
First Trimester ◽  
The Body ◽  
Control Group ◽  
Third Trimester ◽  
Significant Difference ◽  
The Mean ◽  
Mean Concentration

Background: Pregnancy is a major endocrine event in the female lifespan, involving wide-ranged and often dramatic changes in the metabolism of various hormones. Cross sectional, case control, analytical quantitative study was conducted in Sudan, Khartoum state in Yastabsheron obstetric hospital during the period from March to August 2011. Analytical and statistical methods were applied to measure the concentration of A1c% in healthy pregnant women as well as in healthy non-pregnant women to assess the difference in the results.Methods: Blood samples were taken from a total of 90 healthy pregnant women (case group) and 30 healthy non-pregnant women (control group), then samples were analyzed for A1c% by using affinity chromatography technique, and results were recorded in addition to their age, body mass index and the number of pregnancies.Results: showed that, the mean concentration of the A1c% in cases group was (4.407±1.054%) in first trimester, (4.797±0.631) % in second trimester and (4.833±0.626) % in third trimester, and (5.670±0.471%) in control group with a P value of 0.00, indicating the highly significant difference between the two groups. Others finding showed that the mean concentration of A1c% of the first trimester is lower than that of the second and third trimesters, also there was no significant difference between the mean concentration of the second and third trimester. A significant weak positive correlation between A1c% concentration with body mass index and the age of pregnant women.Conclusions: Healthy normal pregnant women have lower A1c% concentrations than non-pregnant women which can be impute to the reduce in plasma glucose values and to the shortened erythrocyte life span that can occur during pregnancy. The body mass index and age affect the concentration of A1c% c, but it is not affected by gravida.

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