scholarly journals The Association of Vitamin A and Vitamin D with Hypertension in Children: A Case-Control Study

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Xiaohua Liang ◽  
Min Chen ◽  
Ping Qu ◽  
Guang Hao ◽  
Yisong Huang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Vitamin A ◽  
Case Control Study ◽  
Serum Vitamin ◽  
Blood Pressure Level ◽  
Case Control ◽  
Pressure Level ◽  
Control Group ◽  
Hypertension In Children ◽  
Control Study

Background. The prevalence of hypertension in children increases rapidly. This paper is to investigate the association of vitamin A and serum 25(OH)D level with hypertension and to explore the risk factors of hypertension in children. Methods. 164 children (age: 6-12 years, females: 49.39%) were included in this case-control study. The serum vitamin A and serum 25(OH)D level, the transcription level of RARs and RXRs, 25(OH)D receptor, and the retinol acyltransferase (LRAT), an indicator of vitamin A storage function, were measured. Results. The serum vitamin A level in hypertensive subjects was not significantly different compared to control, but the serum 25(OH)D level was significantly lower in hypertensive subjects compared to control (38.22±12.00umol/L vs. 43.28±12.33 umol/L, P=0.02). The transcription levels of RARα, RARβ, and RARγ were not significantly different between the two groups; but the LRAT was lower in the hypertensive group than that in the control (P<0.001). Compared with control group, the level of 25(OH)D receptor was lower in hypertension children (P=0.003). Logistic regression model showed that LRAT, HDL, and breastfed duration were negatively associated with blood pressure, and waist circumference was positively associated with blood pressure. Conclusions. The LRAT, serum 25(OH)D, and 25(OH)D receptor were significantly associated with blood pressure level, and both breastfed and HDL-C were independent protective factors of blood pressure level in children.

scholarly journals Long-term excess risk of stroke in people with Type 2 diabetes in Sweden according to blood pressure level: a population-based case-control study

2017 ◽  
Vol 34 (4) ◽  
pp. 522-530 ◽  
Author(s):  
C. Hedén Ståhl ◽  
M. Lind ◽  
A.-M. Svensson ◽  
M. Kosiborod ◽  
S. Gudbjörnsdottir ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Case Control Study ◽  
Blood Pressure Level ◽  
Population Based ◽  
Case Control ◽  
Pressure Level ◽  
Control Study

scholarly journals High Blood Pressure during Pregnancy is not a Protective Factor for Preterm Infants with Very Low Birth Weight. A Case-Control Study

2017 ◽  
Vol 39 (04) ◽  
pp. 155-161 ◽  
Author(s):  
Annibal Sabino ◽  
Eduardo de Souza ◽  
Ana Goulart ◽  
Adriana Lima ◽  
Nelson Sass
Keyword(s):  
Blood Pressure ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Protective Factor ◽  
Case Control Study ◽  
Very Low Birth Weight ◽  
Case Control ◽  
World Health ◽  
Control Group ◽  
Control Study

Objective To evaluate whether the presence of maternal blood pressure reduces the risks of morbidity, perinatal mortality and morbidity at 24 months of age in very low birth weight infants (VLBWIs) compared with a control group. Methods A retrospective, observational, case-control study. Total 49 VLBWIs were allocated to the study group, called the maternal arterial hypertension group (AHG), and matched with 44 in the control group (CG). The infants were assessed during hospitalization and at 12 and 24 months corrected age at a specialized clinic. For the assessment of growth, the World Health Organization (WHO) Anthro software (Geneva, 2006) was used, and for the psychomotor assessment, the Denver II test was used. Results In relation to the antenatal variables, the infants of the AHG had more centralized circulation assessed by Doppler, received more corticosteroids and magnesium sulfate, and were born by cesarean section more frequently. In terms of the postnatal and in-hospital outcomes, the AHG had a higher gestational age at birth (30.7 versus 29.6 weeks) and a lower frequency of 5-minute Apgar scores of less than 7 (26.5% versus 52.3%). The CG had a higher rate of pulmonary dysplasia (30.2% versus 8.3%). There were no differences in terms of hospital mortality, complications, somatic growth and functional problems at 24 months of corrected age. Conclusion The presence of maternal hypertension, especially preeclampsia, was not a protective factor against morbidity, mortality and evolution in VLBWIs aged up to 24 months. Therefore, the clinical practice should be focused on prolonging the pregnancy for as long as possible in these conditions as well.

Oral and pharyngeal cancer, diet, smoking, alcohol, and serum vitamin a and β‐carotene levels: A case‐control study in men

1993 ◽  
Vol 20 (1) ◽  
pp. 61-70 ◽  
Author(s):  
Gabriel A. Kune ◽  
Susan Kune ◽  
Barry Field ◽  
Lyndsey F. Watson ◽  
Heather Cleland ◽  
...  
Keyword(s):  
Vitamin A ◽  
Case Control Study ◽  
Serum Vitamin ◽  
Case Control ◽  
Pharyngeal Cancer ◽  
Oral And Pharyngeal Cancer ◽  
Cancer Diet ◽  
Β Carotene ◽  
Control Study

Association of Cigarette Smoking and Serum Concentrations of Vitamins A and E in Men: A Case-Control Study

2021 ◽  
Author(s):  
Marjan Sohrabi ◽  
Mahmoud Djalali ◽  
Mohammad Hassan Javanbakht ◽  
Niloofar Shekoohi ◽  
Abed Ghavami ◽  
...  
Keyword(s):  
Vitamin E ◽  
Cigarette Smoking ◽  
Vitamin A ◽  
Case Control Study ◽  
Serum Vitamin ◽  
Case Control ◽  
Serum Concentrations ◽  
Blood Concentrations ◽  
Cholesterol Ratio ◽  
Control Study

Background: Cigarette smoking is associated with changes in blood concentrations of some antioxidant vitamins. This study aimed to determine the association of cigarette smoking with serum concentrations of vitamins A and E in men. Methods: This was a case-control study, in which the participants were 80 male smokers and 84 male nonsmokers (age range: 20-60 years). Data on dietary intake, health status, smoking habits, anthropometric characteristics, and vitamin levels were compared between cases and controls. Results: Smokers had significantly lower concentrations of serum vitamin E (p = 0.001) and vitamin A (p = 0.013) compared with nonsmokers. However, serum vitamin E to cholesterol ratio was not significantly different between smokers and nonsmokers. Moreover, the highest circulating concentrations of vitamin E was observed in smokers who smoked ≤9 cigarettes per day (p < 0.03), while and the lowest vitamin E was seen in men smoking ≥20 cigarettes per day. Conclusion: The results of this study identified that cigarette smoking is associated with lower levels of serum vitamin E and vitamin A, although it was not associated with vitamin E to cholesterol ratio.

scholarly journals The lower methylation of RANK is associated with osteoporosis in male aged general population of Xinjiang: A Case-Control Study

2020 ◽  
Author(s):  
Junjing Shang ◽  
Hong xiang ◽  
Xue Bai ◽  
Buluhan Halan ◽  
Hongmei Wang
Keyword(s):  
Blood Pressure ◽  
General Population ◽  
Case Control Study ◽  
Statistical Significance ◽  
Multivariate Logistic Regression Analysis ◽  
Case Control ◽  
Control Group ◽  
Case Group ◽  
Methylation Rate ◽  
Control Study

Abstract Background RANK is a candidate gene for osteoporosis on both functional and genetic grounds. The study is to investigate the relationships between the methylation of RANK and osteoporosis in aged general population. Methods On the basis of an epidemiological investigation, we detect for methylation CpGs in promoter of RANK in 32 aged subjects (16 males and 16 females) firstly. Secondly, after considering the relationships among osteoporosis and the methylation rate of identified CpGs in male and female subjects, the selected representatives CpGs were detected in 90 male aged general subjects (43 controls and 47 cases) by bisulfite sequencing. Then a case-control study is conducted. Results Age and the prevalence of diabetes were significantly difference between the case patients and control individuals (P = 0. 025, P = 0. 005)., There was no statistical significance between the case group and the control group for the following values: systolic blood pressure, diastolic blood pressure, body mass index, 25-dihydroxyvitaminD3, folic acid, testosterone, creatinine, serum calcium concentration, and the prevalence of smoking, drinking and hypertension (P > 0.05). The methylation rate of RANK in control group was significant higher than that in osteoporosis group (P < 0.001). In addition, by covariance analysis to adjust age, prevalence of smoking, drinking, hypertension, and diabetes, the methylation rate of RANK in control group was significant higher than that in osteoporosis group in male aged general population of Xinjiang (P = 0.001). After adjusting for confounding factors (age, smoking, drinking, and diabetes), multivariate logistic regression analysis also showed that lower methylation of RNAK gene were significantly associated with osteoporosis (OR = 0.930, 95% CI = 0.886–0.976) Conclusions The lower methylation rate of RANK was associated with osteoporosis in male aged general population of Xinjiang. This confirms that lower methylation of RANK might be involved in the pathogenesis of osteoporosis

scholarly journals Relationship between serum lipid levels and ischemic stroke in patients with atrial fibrillation: a nested case–control study based on the China Atrial Fibrillation Registry

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Fei Li ◽  
Xin Du ◽  
Liu He ◽  
Chao Jiang ◽  
Shijun Xia ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Blood Pressure ◽  
Ischemic Stroke ◽  
Case Control Study ◽  
Density Lipoprotein ◽  
Case Control ◽  
Control Group ◽  
Stroke Group ◽  
Nested Case Control ◽  
Control Study

Abstract Background Atrial fibrillation (AF) is an important risk factor for acute ischemic stroke. Methods A nested case–control study was conducted among patients diagnosed with AF, whose information was acquired from the prospective China Atrial Fibrillation Registry (China-AF), from August 2011 to December 2018. Results This study compared patients with stroke group (n = 145) with a matched control group (n = 577). Demographic data were similar except for body mass index (BMI), diastolic blood pressure (DBP) which were higher, and new oral anticoagulant (NOAC) treatment rate which was lower in the stroke group (all P < 0.05). Baseline median [IQR] levels of including triglyceride (TG) were higher in the stroke group (21.96 [16.74, 21.52], mg/dL) than the control group (19.62 [14.76, 27.36], mg/dL) (P = 0.012), while the total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) were similar between the two groups. Elevated TG and HDL-C were positively associated with ischemic stroke (OR 1.01, 95% CI 1.00–1.02, P = 0.032; OR 1.03, 95% CI 1.00–1.05, P = 0.025), after adjustment for BMI, systolic blood pressure, DBP, CHA2DS2-VASc score, HAS-BLED score, NOAC, LDL-C and HDL-C. However, NOAC (OR 0.20, 95% CI 0.05–0.84, P = 0.029) could decrease the likelihood of ischemic stroke in patients with AF. In subgroup analysis, higher TG level remained significantly associated with ischemic stroke for AF patients without a history of smoking (OR 1.26, 95% CI 1.02–1.55, P = 0.028). Conclusion Higher level of TG and HDL-C were positively associated with ischemic stroke in patients with AF.

scholarly journals COMPARISON OF SERUM LEVELS OF VITAMIN A, VITAMIN D AND ZINC IN ACUTE LOWER RESPIRATORY TRACT INFECTIONS IN CHILDREN

2020 ◽  
pp. 1-4
Author(s):  
Anil Sharma ◽  
Shalini Dash
Keyword(s):  
Vitamin D ◽  
Vitamin A ◽  
Case Control Study ◽  
Serum Vitamin ◽  
Serum Levels ◽  
Case Control ◽  
Indian Children ◽  
Serum Vitamin D ◽  
Tract Infections ◽  
Control Study

Aim: Acute lower respiratory infections (ALRIs) are global problem, and there are large differences in mortality rates between developed and developing countries. Deficiency of micronutrients may increase the risk of ALRI. A case-control study was conducted to assess the associations between vitamin A, vitamin D, zinc and ALRI in eastern part of Indian children. Methods: Children aged 1 – 60 months hospitalizes with ALRI (cases, N = 51) were matched to controls on age, sex and socio-economic status (N = 31). The mean Serum levels of Vitamin A, Vitamin D (25-hydroxy vitamin D) and Zinc in cases and controls was compared using student's paired t-test and compared the severity of pneumonia with these levels. Results: Mean (SD) level of serum vitamin A, vitamin D and zinc in the cases were 17.08 (±10.53) ìg/dl; 13.91 (±2.99) ng/ml and 61.51 (±13.84) ìg/dl, respectively. The serum vitamin A, vitamin D and zinc levels were significantly lower in cases of ALRI as compared to controls (p<0.001). In our study serum vitamin D level was significantly associated with severity of ALRIs (p=0.042), and mean level of serum vitamin A was significantly low in case of severe pneumonia as compared to pneumonia (p=0.011). Conclusion: Vitamin A, vitamin D and zinc status was associated with childhood ALRI in matched case-control study in eastern part of India. Randomized trials may establish whether interventions to improve theses micronutrients status can reduce the burden of ALRI in children.

scholarly journals THE INFLUENCE OF MICROSOCIAL FACTORS ON THE FORMATION OF ARTERIAL HYPERTENSION IN SCHOOLCHILDREN

2021 ◽  
Vol 11 (1(39)) ◽  
pp. 28-32
Author(s):  
Dmitrо Nechytailo ◽  
T.M. Miheeva ◽  
N.I. Kovtyuk
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Blood Pressure ◽  
Blood Pressure Level ◽  
Pressure Level ◽  
Control Group ◽  
The Family ◽  
Unbalanced Diet ◽  
Vegetables And Fruits ◽  
Hypertension In Children

Introduction. In recent years, there has been anincrease in the prevalence of hypertension in both adults andchildren. The discrepancy in the prevalence of the diseasein children is associated with the absence of a standardizedmethod of measuring blood pressure, uniform criteria forassessing its level, as well as the "hypodiagnostics" ofarterial hypertension in children. Attention should alsobe paid to the relatively low compliance of some childrenand adolescents in the treatment and awareness of the needto maintain a sufficient level of physical activity, healthyeating and prevention of bad habits.The aim of the study was to determine the influence ofmicrosocial factors on the formation of arterial hypertensionin schoolchildren.Material and research methods. 848 school - agechildren were examined and divided into the followinggroups: the first group consisted of 182 children withhypertension, the second group - 78 children with arterialprehypertension and the control group - 588 children withnormal blood pressure.Sociometric survey was conducted by collectinginformation about the peculiarities of diet and quality ofnutrition, physical activity and psychological factors inchildren using questionnaires. Blood pressure level wasmeasured with automatic tonometers with variable cuffs inthe morning on both hands, three times, with an intervalof 2 minutes. The results were evaluated according topercentile tables in terms of age, sex and height. Statisticalprocessing of the obtained data was performed usingMicrosoftOfficeExcel and Statistica 10.0.Results. Analyzing the psychological atmospherewithin the family, it was found that 585 (69.0%) childrencalled the situation within the family good and warm, 100(12.1%) thought that family conditions were bad and 138(16.3%) children did not decide on account of bad or goodrelations within the family.Assessing the peculiarities of nutrition among thesurveyed schoolchildren, it was found that children fromthe 1st group ate the most irrationally. They ate bread andbaked goods more often every day, meat and dairy productsa little less often, and vegetables and fruits even less often.Equally important factors influencing a child’s healthand development are the presence of physical activity, dailyroutine, walks in the fresh air, and so on. Another importantfactor that affects both the general health of the child andhis physical development is regular exercise in sections orclubs.Children from the 1st group have the lowest level ofregular sports, unbalanced diet, and more often havepsychological problems in relationships with peers andparents. Given the data of statistical analysis, thesemicrosocial factors can be regarded as risk factors for thedevelopment of hypertension in schoolchildren.Conclusions. According to the conducted correlativeand cluster analysis, three key groups of microsocial factorsthat affect the level of blood pressure in children can beidentified: the factor of balanced nutrition, psychosocialfactor and the factor of physical activity. The abovefactors are complex, they can be classified to the categoryof risk factors for the development of hypertension inschoolchildren and early prediction of increased bloodpressure in them.

Biopsychosocial Predictors of Cognitive Impairment in the Elderly: A Case-control Study

2020 ◽  
Vol 16 (2) ◽  
pp. 119-126
Author(s):  
Zahra Roshani ◽  
Ahmad-Ali Akbari Kamrani ◽  
Yadollah Abolfathi Momtaz
Keyword(s):  
Blood Pressure ◽  
Cognitive Impairment ◽  
Case Control Study ◽  
Tertiary Education ◽  
Multiple Logistic Regression Analysis ◽  
The Elderly ◽  
Case Control ◽  
Serum Folate ◽  
Control Group ◽  
Control Study

Background: Cognitive impairment is one of the most common diseases in the elderly. Several studies have already been conducted to identify related factors, but few have explored all the factors involved in the development of cognitive problems. Objective: The present study aimed to identify significant biopsychosocial predictors of cognitive impairment. Methods:: This case-control study was conducted on 535 elderly people referred to Shafa Clinic in the city of Tehran in 2017. The biological factors including serum cholesterol, fasting blood sugar, systolic and diastolic blood pressure, vitamin D, vitamin B12, serum folate, serum homocysteine, height, and weight were measured. The psychological variable in this study was a history of depression that was extracted from the medical records. Social network and social support were measured by LSNS-6 and MOS-SSS questionnaires. The SPSS version 25 was used to analyze the data. Results: The mean age of the control group was 68.4 years (SD = 5.89) and of the case group was 71.5 years (SD = 7.37). The results of multiple logistic regression analysis showed age (AOR=1.05; CI:1.089-1.016, p≤0.05,), Secondary education (AOR=0.51; CI:0.266-0.990, p<0.05,), Tertiary education (AOR=0.41; CI:0.212-0.810, p<0.01,), hypertension (AOR=2.16; CI:3.671-1.266, p<0.01) homocysteine level (AOR=1.09; CI:1.147-1.045, p<0.001,), Hypothyroidism (AOR=0.43; CI: 0.226 0.820, p<0.001,), and depression (AOR=4.5; CI:7.163-2.822, p<0.001) to be significant predictors of cognitive impairment. Conclusion: Results of this study showed that low education level, high blood pressure, high level of homocysteine and depression likely increase the risk of cognitive impairment; also, it was implied that timely screening can identify people at risk. The novelty of the present study is that it used a combination of the biopsychosocial factors to predict unique predictors of cognitive impairment.

scholarly journals FAKTOR-FAKTOR YANG MEMPENGARUHI KEJADIAN PNEUMONIA PADA BALITA DI RUMAH SAKIT IBU ANAK PERMATA HATI KABUPATEN KLUNGKUNG TAHUN 2015-2017

2018 ◽  
Vol 5 (2) ◽  
pp. 11
Author(s):  
Dea Eka Manuwati Ramandey ◽  
Ni Made Dian Kurniasari ◽  
Desak Nyoman Widyanthini
Keyword(s):  
Vitamin A ◽  
Random Sampling ◽  
Case Control Study ◽  
Acute Infection ◽  
Simple Random Sampling ◽  
Case Control ◽  
Control Group ◽  
Major Health Problem ◽  
Purposive Sampling ◽  
Control Study

ABSTRAK Pneumonia merupakan proses infeksi akut yang mengenai jaringan paru-paru (alveoli). Pneumonia pada balita di Indonesia masih merupakan masalah kesehatan utama, dilihat dari tingginya angka kepadatan penduduk setiap tahunnya. Salah satu upaya untuk menurunkannya adalah dengan mengetahui faktor faktor yang menyebabkan terjadinya pneumonia. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi kejadian pneumonia pada balita di RSIA Permata Hati Kabupaten Klungkung.  Jenis penelitian ini menggunakan pendekatan kuantitatif analitik dengan rancangan kasus kontrol (case control study). Sampel dari penelitian ini yaitu sebanyak 80 diantaranya 40 ibu yang memiliki balita tidak pneumonia sebagai kelompok kontrol dan 40 ibu yang memiliki balita pneumonia sebagai kelompok kasus. Pengambilan sampel pada kasus dengan simple random sampling dan pada kontrol dengan purposive sampling. Dengan wawancara menggunakan kuesioner.  Analisis data mencakup analisis univariat dan bivariat. Hasil penelitian menunjukkan faktor determinan yang mempengaruhi pada kejadian pneumonia pada balita adalah faktor jenis kelamin (OR= 3,095 95% CI=1,134-8,530;p=0,013), berat badan lahir (OR=12,666 95% CI=2,540-119,627;p=0,0002), pemberian vitamin A (OR=25,705 95% CI=5,610-238,625;p=0,0001),ASI ekslusif (OR=16,333 95% CI=4,628-64,082 ;p= 0,0001),paparan asap rokok (OR=3,44 95% CI=1,191-10,294;p=0,010). Simpulan dari penelitian ini adalah faktor yang mempengaruhi determinan pneumonia pada balita adalah faktor anak dan lingkungannya. Kata kunci:  Pneumonia, Balita, Faktor-faktor ABSTRACT Pneumonia is an acute infection process that affects the lung tissue (alveoli). Pneumonia in toddlers in Indonesia is still a major health problem, seen from the high population density each year. One effort to reduce it is by knowing the factors that cause pneumonia. This study aims to determine the factors that influence the incidence of pneumonia in infants at RSIA Permata Hati, Klungkung Regency. This type of research uses a quantitative analytical approach with a case control study. The samples of this study were 80 of them 40 mothers who had no pneumonia as a control group and 40 mothers who had pneumonia as a case group. Sampling in cases with simple random sampling and in controls with purposive sampling. With interviews using a questionnaire. Data analysis includes univariate and bivariate analysis. The results showed that the determinant factors affecting the incidence of pneumonia in infants were gender (OR = 3,095 95% CI = 1,134-8,530; p = 0.013), birth weight (OR = 12,666 95% CI = 2,540-119,627; p = 0,0002), giving vitamin A (OR = 25,705 95% CI = 5,610-238,625; p = 0,0001), exclusive breastfeeding (OR = 16,333 95% CI = 4,628-64,082; p = 0,0001), smoke exposure cigarettes (OR = 3.44 95% CI = 1,191-10,294; p = 0.010). The conclusions of this study are the factors that influence the determinants of pneumonia in toddlers are the factors of children and their environment. Keywords:  Pneumonia, toddler, the factors

Sign in / Sign up

Export Citation Format

Share Document