scholarly journals Layered 3D Printing by Tethered Pyro-Electrospinning

2020 ◽  
Vol 2020 ◽  
pp. 1-9 ◽  
Author(s):  
Sara Coppola ◽  
Giuseppe Nasti ◽  
Veronica Vespini ◽  
Pietro Ferraro
Keyword(s):  
3D Printing ◽  
Three Dimensional ◽  
Multiwall Carbon Nanotubes ◽  
Processing Parameters ◽  
Layer By Layer ◽  
Biocompatible Polymer ◽  
Intrinsic Factors ◽  
Electric Effect ◽  
Mild Temperature

Nowadays it is easy to imagine that the exploitation of different additive manufacturing approaches could find use in regenerative medicine and frontiers nanotechnology with a strong interest in the development of in vivo bio-incubators that better replicate the tissue environment. Various electrospinning technologies have been exploited for the fabrication of composite polymeric architectures, where fibers have been used for the construction layer by layer of micro-architectures. Unfortunately, in case of processing biomaterials, the intrinsic factors of the materials could become obstacles when considering such advanced engineering methods. Here, for the first time, we use the pyro-EHD process for the fabrication of layered three-dimensional architectures made using a biodegradable and biocompatible polymer. The proposed approach for layered 3D printing works at mild temperature allowing deposition at high resolution and great flexibility in manufacturing, avoiding high voltage generators, and nozzles. The layered 3D printing, activated by the pyro-electric effect, is discussed and characterized in terms of geometrical features and processing parameters. Different geometries and micro-architecture (wall, square, triangle, and hybrid structures) have been demonstrated and over printing of composite polymer, obtained by mixing multiwall carbon nanotubes and fluorochrome, has been discussed, focusing on the use of a biodegradable and biocompatible polymer.

scholarly journals A pilot study on the use of 3D printers in veterinary medicine

2021 ◽  
Vol 14 (3) ◽  
pp. 159-164
Author(s):  
Leonardo Leonardi ◽  
◽  
Roberto Marsili ◽  
Enrico Bellezza ◽  
Giovanni Angeli ◽  
...  
Keyword(s):  
Additive Manufacturing ◽  
3D Printing ◽  
Bone Tissue ◽  
Three Dimensional ◽  
The Body ◽  
Porous Scaffolds ◽  
Layer By Layer ◽  
Three Dimensional Objects ◽  
Cellular Attachment

Additive manufacturing (AM) is the process of joining materials to create layer-by-layer three-dimensional objects using a 3D printer from a digital model. The great advantage of Additive Manufacturing is to allow a freer design than traditional processes. The development of additive manufacturing processes has permitted to optimize the production of the customized product through the modeling of the geometry and the knowledge of the morphometric parameters of the body structures. 3D printing has revolutionized the field of Regenerative Medicine because, starting from computerized tomography (CT) images and using traditional materials such as plastic and metals, it can provide customized prostheses for each patient, which adapt perfectly to the needs of the subject and act as structures support. 3D printing allows you to print three-dimensional porous scaffolds with a precise shape and chemical composition suitable for medical and veterinary use. Some of these scaffolds are biodegradable and appear to be ideal for bone tissue engineering. In fact, they are able to simulate extracellular matrix properties that allow mechanical support, favoring mechanical interactions and providing a model for cellular attachment and in vivo stimulation of bone tissue formation.

scholarly journals A guideline for 3D printing terminology in biomedical research utilizing ISO/ASTM standards

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Amy E. Alexander ◽  
Nicole Wake ◽  
Leonid Chepelev ◽  
Philipp Brantner ◽  
Justin Ryan ◽  
...  
Keyword(s):  
3D Printing ◽  
Medical Literature ◽  
Three Dimensional ◽  
Physical Object ◽  
Medical Community ◽  
Layer By Layer ◽  
Digital File ◽  
Standardized Terminology ◽  
Standard Terms ◽  
The Impact

AbstractFirst patented in 1986, three-dimensional (3D) printing, also known as additive manufacturing or rapid prototyping, now encompasses a variety of distinct technology types where material is deposited, joined, or solidified layer by layer to create a physical object from a digital file. As 3D printing technologies continue to evolve, and as more manuscripts describing these technologies are published in the medical literature, it is imperative that standardized terminology for 3D printing is utilized. The purpose of this manuscript is to provide recommendations for standardized lexicons for 3D printing technologies described in the medical literature. For all 3D printing methods, standard general ISO/ASTM terms for 3D printing should be utilized. Additional, non-standard terms should be included to facilitate communication and reproducibility when the ISO/ASTM terms are insufficient in describing expository details. By aligning to these guidelines, the use of uniform terms for 3D printing and the associated technologies will lead to improved clarity and reproducibility of published work which will ultimately increase the impact of publications, facilitate quality improvement, and promote the dissemination and adoption of 3D printing in the medical community.

scholarly journals Three-dimensionally printed polycaprolactone/multicomponent bioactive glass scaffolds for potential application in bone tissue engineering

2020 ◽  
Vol 6 (1) ◽  
pp. 57-69
Author(s):  
Amirhosein Fathi ◽  
Farzad Kermani ◽  
Aliasghar Behnamghader ◽  
Sara Banijamali ◽  
Masoud Mozafari ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Three Dimensional ◽  
Layer By Layer ◽  
Composite Scaffolds ◽  
3D Printed ◽  
Co Doped

AbstractOver the last years, three-dimensional (3D) printing has been successfully applied to produce suitable substitutes for treating bone defects. In this work, 3D printed composite scaffolds of polycaprolactone (PCL) and strontium (Sr)- and cobalt (Co)-doped multi-component melt-derived bioactive glasses (BGs) were prepared for bone tissue engineering strategies. For this purpose, 30% of as-prepared BG particles (size <38 μm) were incorporated into PCL, and then the obtained composite mix was introduced into a 3D printing machine to fabricate layer-by-layer porous structures with the size of 12 × 12 × 2 mm3.The scaffolds were fully characterized through a series of physico-chemical and biological assays. Adding the BGs to PCL led to an improvement in the compressive strength of the fabricated scaffolds and increased their hydrophilicity. Furthermore, the PCL/BG scaffolds showed apatite-forming ability (i.e., bioactivity behavior) after being immersed in simulated body fluid (SBF). The in vitro cellular examinations revealed the cytocompatibility of the scaffolds and confirmed them as suitable substrates for the adhesion and proliferation of MG-63 osteosarcoma cells. In conclusion, 3D printed composite scaffolds made of PCL and Sr- and Co-doped BGs might be potentially-beneficial bone replacements, and the achieved results motivate further research on these materials.

scholarly journals Porous PLAs with Controllable Density by FDM 3D Printing and Chemical Foaming Agent

Micromachines ◽  
2021 ◽  
Vol 12 (8) ◽  
pp. 866
Author(s):  
A. R. Damanpack ◽  
André Sousa ◽  
M. Bodaghi
Keyword(s):  
3D Printing ◽  
Flow Rate ◽  
Three Dimensional ◽  
Poly Lactic Acid ◽  
Layer By Layer ◽  
Printing Technology ◽  
Material Density ◽  
Foaming Agent ◽  
3D Printing Technology ◽  
Fabrication Parameters

This paper shows how fused decomposition modeling (FDM), as a three-dimensional (3D) printing technology, can engineer lightweight porous foams with controllable density. The tactic is based on the 3D printing of Poly Lactic Acid filaments with a chemical blowing agent, as well as experiments to explore how FDM parameters can control material density. Foam porosity is investigated in terms of fabrication parameters such as printing temperature and flow rate, which affect the size of bubbles produced during the layer-by-layer fabrication process. It is experimentally shown that printing temperature and flow rate have significant effects on the bubbles’ size, micro-scale material connections, stiffness and strength. An analytical equation is introduced to accurately simulate the experimental results on flow rate, density, and mechanical properties in terms of printing temperature. Due to the absence of a similar concept, mathematical model and results in the specialized literature, this paper is likely to advance the state-of-the-art lightweight foams with controllable porosity and density fabricated by FDM 3D printing technology.

Steel Parts with Tailored Material Gradients by 3D-Printing Using Nano-Particulate Ink

2005 ◽  
Vol 492-493 ◽  
pp. 679-684 ◽  
Author(s):  
Dirk Godlinski ◽  
Stéphane Morvan
Keyword(s):  
3D Printing ◽  
Solid Freeform Fabrication ◽  
Three Dimensional ◽  
Material Design ◽  
Nano Particles ◽  
Layer By Layer ◽  
Steel Matrix ◽  
Local Composition ◽  
Composition Control ◽  
Halftone Image

It is difficult to generate any user-defined three dimensional gradient to tailor the functional properties of a component. Problems are not only the lack of local material design tools, but also a suitable manufacturing process. The implementation of the concept of local composition control into the Solid Freeform Fabrication (SFF) process 3D-Printing is described, which leads to geometrical complex parts out of tailored materials. Suspensions of different functional inks containing a binder and carbon black nano-particles are dispensed into droplets through multiple jets – like inkjet printing a halftone image on a paper – but into a metal powder bed to generate layer by layer graded green parts. In this case the tailored preforms are then sintered, while the nano-particle additions from the functional ink act locally as alloying elements in the steel matrix to combine e.g. both, toughness and hardness in the part. This work concentrates on the realisation of the new process and shows first results taking the generation of carbon-graded steel parts as an example.

scholarly journals 3D PRINTING AND 3D BIOPRINTING TO USE FOR MEDICAL APPLICATIONS

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Milan Šljivić ◽  
Dragoljub Mirjanić ◽  
Nataša Šljivić ◽  
Cristiano Fragassa ◽  
Ana Pavlović
Keyword(s):  
3D Printing ◽  
Three Dimensional ◽  
3D Models ◽  
Physical Models ◽  
Layer By Layer ◽  
3D Bioprinting ◽  
Solid Objects ◽  
Modern Methods ◽  
Digital File

The Additive manufacturing 3D printing is a process of creating a three dimensional solid objects or rapid prototyping of 3D models from a digital file, which builds layer by layer. The 3D bioprinting is a form sophisticated of 3D printing technology involving cells and tissues for the production of tissue for regenerative medicine, which is also built layer by layer into the area of human tissue or organ. This paper defines the modern methods and materials of the AM, which are used for the development of physical models and individually adjusted implants for 3D printing for medical purposes. The main classification of 3D printing and 3D bioprinting technologies are also defined by typical materials and a field of application. It is proven that 3D printing and 3D bioprinting techniques have a huge potential and a possibility to revolutionize the field of medicine.

scholarly journals 3D Printing of Bioceramic Scaffolds—Barriers to the Clinical Translation: From Promise to Reality, and Future Perspectives

Materials ◽  
2019 ◽  
Vol 12 (17) ◽  
pp. 2660 ◽  
Author(s):  
Kang Lin ◽  
Rakib Sheikh ◽  
Sara Romanazzo ◽  
Iman Roohani
Keyword(s):  
3D Printing ◽  
Polymer Matrix Composites ◽  
Three Dimensional ◽  
Processing Parameters ◽  
Matrix Composites ◽  
Large Area ◽  
Digital Light Processing ◽  
Increasing Demand ◽  
New Research ◽  
Porous Bioceramics

In this review, we summarize the challenges of the three-dimensional (3D) printing of porous bioceramics and their translational hurdles to clinical applications. The state-of-the-art of the major 3D printing techniques (powder-based and slurry-based), their limitations and key processing parameters are discussed in detail. The significant roadblocks that prevent implementation of 3D printed bioceramics in tissue engineering strategies, and medical applications are outlined, and the future directions where new research may overcome the limitations are proposed. In recent years, there has been an increasing demand for a nanoscale control in 3D fabrication of bioceramic scaffolds via emerging techniques such as digital light processing, two-photon polymerization, or large area maskless photopolymerization. However, these techniques are still in a developmental stage and not capable of fabrication of large-sized bioceramic scaffolds; thus, there is a lack of sufficient data to evaluate their contribution. This review will also not cover polymer matrix composites reinforced with particulate bioceramics, hydrogels reinforced with particulate bioceramics, polymers coated with bioceramics and non-porous bioceramics.

scholarly journals Parameters Affecting the Mechanical Properties of Three-Dimensional (3D) Printed Carbon Fiber-Reinforced Polylactide Composites

Polymers ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 2456
Author(s):  
Demei Lee ◽  
Guan-Yu Wu
Keyword(s):  
Mechanical Properties ◽  
Carbon Fiber ◽  
3D Printing ◽  
Three Dimensional ◽  
Fused Deposition Modelling ◽  
Layer By Layer ◽  
Fused Deposition ◽  
Bed Temperature ◽  
3D Printed ◽  
The Impact

Three-dimensional (3D) printing is a manufacturing technology which creates three-dimensional objects layer-by-layer or drop-by-drop with minimal material waste. Despite the fact that 3D printing is a versatile and adaptable process and has advantages in establishing complex and net-shaped structures over conventional manufacturing methods, the challenge remains in identifying the optimal parameters for the 3D printing process. This study investigated the influence of processing parameters on the mechanical properties of Fused Deposition Modelling (FDM)-printed carbon fiber-filled polylactide (CFR-PLA) composites by employing an orthogonal array model. After printing, the tensile and impact strengths of the printed composites were measured, and the effects of different parameters on these strengths were examined. The experimental results indicate that 3D-printed CFR-PLA showed a rougher surface morphology than virgin PLA. For the variables selected in this analysis, bed temperature was identified as the most influential parameter on the tensile strength of CFR-PLA-printed parts, while bed temperature and print orientation were the key parameters affecting the impact strengths of printed composites. The 45° orientation printed parts also showed superior mechanical strengths than the 90° printed parts.

Additive Manufacturing

2019 ◽  
pp. 165-183 ◽  
Author(s):  
Kamardeen Olajide Abdulrahman ◽  
Esther T. Akinlabi ◽  
Rasheedat M. Mahamood
Keyword(s):  
Mechanical Properties ◽  
Additive Manufacturing ◽  
Titanium Aluminide ◽  
Three Dimensional ◽  
Physical And Mechanical Properties ◽  
Processing Parameters ◽  
Metal Deposition ◽  
Layer By Layer ◽  
Laser Metal Deposition ◽  
Additive Process

Three-dimensional printing has evolved into an advanced laser additive manufacturing (AM) process with capacity of directly producing parts through CAD model. AM technology parts are fabricated through layer by layer build-up additive process. AM technology cuts down material wastage, reduces buy-to-fly ratio, fabricates complex parts, and repairs damaged old functional components. Titanium aluminide alloys fall under the group of intermetallic compounds known for high temperature applications and display of superior physical and mechanical properties, which made them most sort after in the aeronautic, energy, and automobile industries. Laser metal deposition is an AM process used in the repair and fabrication of solid components but sometimes associated with thermal induced stresses which sometimes led to cracks in deposited parts. This chapter looks at some AM processes with more emphasis on laser metal deposition technique, effect of LMD processing parameters, and preheating of substrate on the physical, microstructural, and mechanical properties of components produced through AM process.

Importance of 3D Printing Technology in Medical Fields

2019 ◽  
pp. 21-40
Author(s):  
Ranjit Barua ◽  
Sudipto Datta ◽  
Amit Roychowdhury ◽  
Pallab Datta
Keyword(s):  
Tissue Engineering ◽  
Additive Manufacturing ◽  
3D Printing ◽  
New Technology ◽  
Three Dimensional ◽  
Layer By Layer ◽  
Medical Field ◽  
Printing Technology ◽  
3D Printing Technology ◽  
Proper Material

Three-dimensional or 3D printing technology is a growing interest in medical fields like tissue engineering, dental, drug delivery, prosthetics, and implants. It is also known as the additive manufacturing (AM) process because the objects are done by extruding or depositing the material layer by layer, and the material may be like biomaterials, plastics, living cells, or powder ceramics. Specially in the medical field, this new technology has importance rewards in contrast with conventional technologies, such as the capability to fabricate patient-explicit difficult components, desire scaffolds for tissue engineering, and proper material consumption. In this chapter, different types of additive manufacturing (AM) techniques are described that are applied in the medical field, especially in community health and precision medicine.

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