scholarly journals Risk Factors in Outpatients with Dermatitis and Eczema in Tertiary Hospitals of China Who Have Clinically Suspected Bacterial Infection

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Yan Li ◽  
Wei Xu ◽  
Linfeng Li

Skin bacterial infections are often observed in eczema patients, but the risk factors are not fully understood. The current study evaluated the prevalence of clinically suspected bacterial infection and its associated risk factors. Moreover, we investigated the practice of skin infection diagnosis in China. A hospital-based, multicenter, cross-sectional epidemiologic survey of bacterial infection was performed in a total of 6208 outpatients diagnosed with dermatitis and eczema from 39 tertiary hospitals of 15 provinces and municipalities in China. All patients completed a specific questionnaire regarding their demographic characteristics, disease duration, distribution of lesions, severity of itching, and medical history. Univariate analysis and multivariate analysis were used to evaluate risk factors associated with bacterial infection in patients with different types of eczema. The prevalence of clinically suspected bacterial infection was 47.0% in patients with eczema. Compared to atopic dermatitis, widespread eczema ( OR = 1.50 , P < 0.001 ) and other eczema ( OR = 1.42 , P < 0.001 ) were more likely to suffer bacterial infection. The itching grade was positively associated with the infection ( OR = 2.11 , 7.04, and 12.3 in patients with mild, moderate, and severe itching, respectively; P < 0.001 ). Lesion distribution in the cubital fossa, popliteal fossa, ear, shoulder and back, axillary, foot, and pudendum was positively associated with bacterial infection (all OR > 1.0 , P < 0.05 ). In contrast, the face and abdomen were reversely associated with bacterial infection ( OR < 1.0 , P < 0.005 ). History of asthma, allergic rhinitis, allergic conjunctivitis, atopic dermatitis, infantile eczema, and flexion dermatitis was positively associated with bacterial infection (all OR > 1.0 , P < 0.005 ), while the history of dry skin was reversely associated with bacterial infection ( OR = 0.76 , 95% CI: 0.64-0.90; P = 0.002 ). Patients with eczema were easily infected with bacteria. Widespread eczema and other eczema were more likely to have bacterial infection than atopic dermatitis. The high rate of infection may attribute to the lack of corresponding bacterial detection, suggesting the need of guideline development in China to prevent overuse of topical antibiotics.

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Xin Wang ◽  
Lin-Feng Li ◽  
Da-yu Zhao ◽  
Yi-wei Shen

Background. The epidemiology of atopic dermatitis (AD) in Chinese outpatients is yet to be clarified.Objectives. To investigate population-based prevalence and clinical features of AD in Chinese outpatients.Methods. A multicenter cross-sectional study was conducted in outpatients with eczema or dermatitis from 39 tertiary hospitals in 15 provinces.Results. This study included 682 patients diagnosed with AD, with the mean age of28.8±20.1years and the median course of5.3±6.9years. AD patients had more severe itching (30.4% versus 13.8%,p<0.001) and clinically suspected bacterial infection (21.7% versus 16.1%,p<0.001) than those of other types of dermatitis. Older patients were more susceptible to have a history of flexion dermatitis (p<0.001), bacterial infection (p=0.005), and severe itching (p<0.001). Outpatients with clinically suspected bacterial infection had 3.53-fold increased risk of AD than those without it (p<0.001). The morbidity rate of AD in the (20–25°N) region is 2.86 times higher than that in the (40–45°N) region [OR (95% CI): 0.352 (0.241–0.514),p<0.001].Conclusions. AD is characterized by unique clinical/demographic features. Bacterial infection and latitude region may have an impact on the incidence of AD in China.


BMJ Open ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. e032604
Author(s):  
Regine Mugeni ◽  
Eugene Nkusi ◽  
Eric Rutaganda ◽  
Sanctus Musafiri ◽  
Florence Masaisa ◽  
...  

ObjectivesTo determine the prevalence of proximal deep vein thrombosis (DVT) by ultrasound scanning, as well as associated clinical features and known risk factors, among medical and obstetrics–gynaecology inpatients in two Rwandan tertiary hospitals.DesignCross-sectional study.SettingsRwanda teaching hospitals: Kigali and Butare University Teaching Hospitals.Participants901 adult patients admitted to the Departments of Internal Medicine and Obstetrics–Gynecology (O&G) who were at least 21 years of age and willing to provide a consent.OutcomesPrevalence of proximal DVT, clinical features and known risk factors associated with DVT.MethodsBetween August 2015 and August 2016, participants were screened for DVT by compressive ultrasound of femoral and popliteal veins, conducted as a monthly cross-sectional survey of all consenting eligible inpatients. Patients completed a self-report survey on DVT risk factors. Prevalence of proximal DVT by compression ultrasonography was the primary endpoint, with univariate and multivariate regression analyses performed to assess associated clinical features and risk factors.ResultsProximal DVT was found in 5.5% of the study population, with similar rates in medical and O&G inpatients. The mean age was 41±16 SD (range, 21–91), 70% were female and 7% were pregnant. Univariate analysis showed active malignancy, immobilisation, prolonged recent travel and history of DVT to be significant risk factors for proximal DVT (all p values <0.05); while only active malignancy was an independent risk factor on multivariate regression (OR 5.2; 95% CI 2.0 to 13). Leg pain or tenderness, increased calf circumference, unilateral limb swelling or pitting oedema were predictive clinical features of DVT on both univariate analysis and multivariate regression (all p values <0.05).ConclusionProximal DVT prevalence is high among hospitalised medical and O&G patients in two tertiary hospitals in Rwanda. For reducing morbidity and mortality, research to develop Africa-specific clinical prediction tools for DVT and interventions to increase thromboprophylaxis use in the region are urgently needed.


2021 ◽  
pp. e20210157
Author(s):  
Mariana Bueno Manini1 ◽  
Natasha Yumi Matsunaga1,2 ◽  
Lívea Gianfrancesco1,2 ◽  
Marina Simões Oliveira1,2 ◽  
Maria Rosa Vieira de Carvalho3 ◽  
...  

Objective: To determine the prevalence of recurrent wheezing (RW) in preterm infants who received prophylaxis against severe infection with respiratory syncytial virus (RSV) and to identify genetic susceptibility (atopy or asthma) and risk factors for RW. Methods: This was a cross-sectional study involving preterm infants who received prophylaxis with palivizumab at a referral center in Brazil during the first two years of age. A structured questionnaire was administered in a face-to-face interview with parents or legal guardians. Results: The study included 410 preterm infants (median age = 9 months [0-24 months]). In the sample as a whole, 111 children (27.1%; [95% CI, 22.9-31.5]) had RW. The univariate analysis between the groups with and without RW showed no differences regarding the following variables: sex, ethnicity, maternal level of education, gestational age, birth weight, breastfeeding, number of children in the household, day care center attendance, pets in the household, and smoking caregiver. The prevalence of RW was twice as high among children with bronchopulmonary dysplasia (adjusted OR = 2.08; 95% CI, 1.11-3.89; p = 0.022) and almost five times as high among those with a personal/family history of atopy (adjusted OR = 4.96; 95% CI, 2.62-9.39; p < 0.001) as among those without these conditions. Conclusions: Preterm infants who received prophylaxis with palivizumab but have a personal/family history of atopy or bronchopulmonary dysplasia are more likely to have RW than do those without these conditions.


2021 ◽  
Vol 6 (2) ◽  
pp. 43-47
Author(s):  
Adawiyah Jamil ◽  
Siew Wen Goh ◽  
Chon Sian Lee ◽  
Mohan Arumugam

Introduction: The atopic march consists of atopic dermatitis (AD), allergic rhinitis or sinusitis (AR), allergic conjunctivitis (AC) and bronchial asthma (BA). The influence of concomitant atopic diseases on AD is under-explored. We determined the relationship between personal and family history of atopic diseases with AD severity and persistence. Methods: A cross sectional study involving AD patients was performed at dermatology clinics of two tertiary hospitals. Inclusion criterion was all patients diagnosed with AD. Demographic data, personal and family history of atopy (BA, AR and AC) were obtained by face-to-face interview. AD severity was evaluated using Investigator’s Global Assessment (IGA). AD was considered persistent if continued beyond age 12 years. Results: Sixty patients aged 21.6±17.2 participated. There were 25(41.7%) with concomitant AR, 16(26.7%) BA and 12(20%) AC. Forty seven (78.3%) patients had family history of atopy, 25(41.7%) had eczema, 24(40%) AR, 19(31.7%) BA and 2(3.3%) AC. Patients with BA [OR=3.8, 95%CI 1.04 to 14.4)], BA and AR [OR=9.74, 95%CI 1.13 to 83.67) and family history of BA [OR= 4.00, 95%CI 1.20 to 13.27) were more likely to exhibit moderate-severe AD. Personal AR, AC and family history of AD and BA were significantly more prevalent in patients with persistent AD. Conclusions: AR was the most common atopic disease associated with AD. Family history of eczema and AR were common. Personal BA, BA with AR and family history of BA were predictors of severe AD. Personal AR, AC and family history of AD and BA were associated with AD persistence.


2017 ◽  
Vol 4 (2) ◽  
pp. 110
Author(s):  
Ridha Fahliati Dewi ◽  
Abdurrahman Wahid ◽  
Ifa Hafifah

ABSTRAKTingkat kejadian meninggalnya pasien STEMI dalam waktu 24 jam diikuti oleh faktor risiko akan mempengaruhi prognosis, maka perlu untuk mengetahui faktor risiko apa saja yang ikut berperan pada STEMI sebagai pencegahan untuk menurunkan angka kejadian mortalitas.Tujuan penelitian ini untuk mengidentifikasi gambaran faktor risiko pada kejadian mortalitas pasien STEMI di RSUD Ulin Banjarmasin.Metode penelitian ini cross sectional dengan  accidental sampling yang dianalisis univariat. Data diambil dari lembar EKG, anamnesa pasien dan keluarga, pernyataan perawat dan dokter dituliskan dalam rekam medik yang diisi langsung oleh peneliti di lembar observasi di RSUD UlinBanjarmasin pada November - Desember 2015. Hasilmenunjukkan17 pasien mengalami STEMI dengan angka mortalitas (11,8%), rata-rata usia pasien STEMI 57 tahun, didominasi laki-laki (88,2%) dengan faktor risiko riwayat penyakit jantung (35,5%), hipertensi (29,4%), merokok (29,4%), stroke (5,9%) dan tidak memiliki riwayat penyakit (17,6%).Kesimpulan penelitianini adalah pasien STEMI di RSUD Ulin Banjarmasin rata-rata berusia 57 tahun dan lebih sering terjadi pada laki-laki dengan faktor risiko riwayat penyakit jantung, hipertensi, merokok, stroke dan tidak memiliki riwayat penyakit.Kata-kata kunci: faktor risiko, STEMI, mortalitas.ABSTRACTThis incidence rate of STEMI patients followed by risk factors that affect prognosis of STEMI patients, there’s a need to acknowledge what risk factors that role in STEMI as prevention to decrease mortality incidence.The objectives was to describe risk factors of mortality incidence in STEMI patients in RSUD Ulin Banjarmasin. This study used cross sectional with accidental sampling method that showed through univariate analysis. The data taken from ECG sheet, patient and family interviewed, nurse and doctor declaration written on medical record that being record directly by researcher on observational sheet in RSUD Ulin Banjarmasin since November - December 2015. The results17 patients having STEMIwith mortality rate (11,8%) average age STEMI patients is 57 years old, dominated bymales (88,2%)withrisk factors are history of prior heart (35,5%), hypertension (29,4%), smoking (29,4%), stroke (5,9%), no medical history (17,6%). The result of this studywasavaregeage of STEMI patients in RSUD Ulin Banjarmasin was 57 years old and the most common in males with risk factors werehistory of prior heart, hypertension, smoking, stroke and no medical history.Keywords: risk factor, STEMI, mortality.


2020 ◽  
Vol 7 ◽  
pp. 2333794X2097000
Author(s):  
Amha Mekasha ◽  
Zelalem Tazu ◽  
Lulu Muhe ◽  
Mahlet Abayneh ◽  
Goitom Gebreyesus ◽  
...  

Aim. To determine the risk factors for death among preterm neonates. Methods and materials. The data set used was derived from a prospective, multi-center, observational clinical study conducted in 5 tertiary hospitals in Ethiopia from July, 2016 to May, 2018. Subjects were infants admitted into neonatal intensive care unit. Results. Risk factors were determined using statistical model developed for this study. The mean gestational age was 32.87 (SD ± 2.42) weeks with a range of 20 to 36 weeks. There were 2667 (70.69%) survivors and 1106 (29.31%) deaths. The significant risk factors for preterm death were low gestational age, low birth weight, being female, feeding problem, no antenatal care visits and vaginal delivery among mothers with higher educational level. Conclusions. The study identified several risk factors for death among preterm neonates. Most of the risk factors are preventable. Thus, it is important to address neonatal and maternal factors identified in this study through appropriate ANC and optimum infant medical care and feeding practices to decrease the high rate of preterm death.


2015 ◽  
Vol 4 (2) ◽  
Author(s):  
Isnaniyah Usman ◽  
Eva Chundrayetti ◽  
Oea Khairsyaf

AbstrakAsma merupakan gangguan inflamasi kronik saluran pernafasan yang sering dijumpai pada anak. Penyakit ini memiliki banyak faktor risiko dan faktor pencetus. Beberapa diantara faktor tersebut adalah jenis kelamin, usia, riwayat atopi, makanan, perubahan cuaca, aktivitas, berat badan lahir, status gizi, pemberian ASI dan debu. Tujuan penelitian ini adalah untuk mengetahui faktor risiko dan faktor pencetus yang mempengaruhi kejadian asma pada anak di RSUP Dr. M. Djamil Padang. Ini adalah penelitian deskriptif dengan desain cross-sectional. Penelitian dilakukan dengan melakukan wawancara pada responden yang telah ditetapkan sebagai subjek penelitian. Subjek penelitian adalah seluruh pasien anak baik rawat jalan maupun rawat inap yang telah didiagnosis asma oleh dokter di RSUP Dr. M. Djamil Padang yang memenuhi kriteria. Penelitian dilakukan dari Februari sampai Maret 2013. Hasil penelitian menunjukkan bahwa faktor risiko dan faktor pencetus yang mempengaruhi asma pada anak adalah perubahan cuaca (65,91%), debu (63,64%), jenis kelamin (52,80%), makanan (43,19%), urtikaria pada anak (38,64%), rhinitis pada anak (34,09%), dermatitis atopi pada ibu (31,82%), dermatitis atopi pada anak (29,55%), aktivitas (27,27%), rhinitis pada ibu (22,72%), asma pada ibu (22,72%), urtikaria pada ayah (20,45%), berat badan lahir <2500 gram (15,91%) dan status gizi (obesitas) 2,28%. Berdasarkan hasil penelitian, kejadian asma banyak terjadi pada laki-laki, sebagian besar dipengaruhi oleh perubahan cuaca dan debu, riwayat atopi terbanyak pada anak adalah urtikaria, riwayat atopi terbanyak pada orangtua adalah dermatitis atopi pada ibu dan status gizi serta berat badan lahir pasien sebagian besar normal.Kata kunci: asma pada anak, faktor risiko, faktor pencetus AbstractAsthma is a cronic inflammatory disorder of respiratory tract that is often found in children. It has many risk faktor and inducer. Some of these risk are gender, age, history of atopy, food, climate change, activity, weight of birth, nutritional status, breastfeeding and dust. The objective of this study was to determine the risk factors and inducer that affect the incidence of asthma in children at the hospital of Dr. M. Djamil Padang. This was a descriptive study that use cross-sectional design. The study was conducted by interview to respondents who had been designated as a research subject. The subjects were all pediatric patients both inpatient and outpatient care that have been diagnosed as asthma by a physician in the hospital of Dr. M. Djamil Padang that have the criteria. The study done from February until March 2013. The result of the research showed that the risk factors and inducer that affect asthma in children are a weather change (65.91%), dust (63.64%), gender (52.80%), food (43.19%), urticaria in children ( 38.64%), rhinitis in children (34.09%), atopic dermatitis in women (31.82%), atopic dermatitis in children (29.55%), activity (27.27%), rhinitis in the mother ( 22.72%), asthma in women (22.72%), urticaria on the father (20.45%), birth weight <2500 g (15.91%) and nutritional status (obesity) 2.28%. Based on these results, the incidence of asthma more common in men, largely influenced by changes in the weather and dust, most history of atopy in children is urticaria, parental history of atopy was highest in atopic dermatitis and maternal.Keywords: asthma in chidren, risk factor, inducer


Author(s):  
Almira Maharani ◽  
Aditiawarman Aditiawarman ◽  
Widati Fatmaningrum

Introduction: Preterm birth becomes a global problem due to its high rate of morbidity and mortality. In 2010, it is estimated approximately 15 premature birth cases per 100 lives birth in Indonesia. This study aimed to analyze the maternal risk factors towards preterm birth at Universitas Airlangga Hospital Surabaya in 2017-2018.Methods: This was observational analytic study using case-control approach to observe 178 medical records at Universitas Airlangga Hospital Surabaya. The population of this study was women who had preterm and aterm birth. The sample consisted of case group and control group which were convenient to exclusion and inclusion criteria. Univariate analysis was used to observe the relationship between dependent and independent variable. The significance value was p ≤ 0.05. The data were analysed using SPSS.Results: The research samples consisted of 89 case groups and 89 control groups. The case sample characteristic showed that 36% patients had overweight BMI; 62.9% patients had normal/hypotension; 69.7% patients gave birth to male baby; and 82% patients had no history of disease.There was no patient who used drugs and substance abuse (0%). Mothers aged 20 years old and older than 35 years old had OR = 2.13 (95% CI : 1.106-4.11) to become preterm birth. The primiparous women had risk for preterm birth 2.978 folds (95%, CI : 576-5.625) higher.Conclusion: There was a relationship between maternal age and parity to preterm birth. There was no relationship between maternal education, maternal occupation, hemoglobin levels, history of obstetric complications, and multiple pregnancy to preterm birth.


MedPharmRes ◽  
2018 ◽  
Vol 2 (2) ◽  
pp. 21-31
Author(s):  
Nguyen Phan ◽  
Hien Pham ◽  
Thuc Nguyen ◽  
Hoai Nguyen

Staphylococcus aureus (S. aureus) has long been recognized as an important human pathogen causing many severe diseases. It is also a part of human normal flora with its ecological niche in the human anterior nares. This study focused on screening S. aureus nasal carriage in community and its relationship to human physiological and pathological factors which have not been studied in Vietnam previously. Two hundred and five volunteers in Ho Chi Minh City from 18 to 35 and over 59 years old both male and female participated in the study. Result showed that the prevalence of S. aureus nasal carriage in southern Vietnamese community was relatively low, only 11.2% (23/205), much lower than that in other international reports on human S. aureus. In addition, nasal carriage of the older age group (> 59 years old, 13.7%) was higher than that of younger age (18-35 years old, 10.4%). Other potential risk factors such as gender, career, height, weight, history of antibiotic usage, daily nasal wash, use of nasal medication sprays, acne problems, smoking and nasal problems showed no significant impact on S. aureus carriage. The obtained S. aureus nasal isolates were all sensitive to vancomycin. Lincomycin and tetracycline had low resistance rate with 4.3 % and 17.4 %, respectively. However, the isolates showed particularly high rate of multidrug resistance (54.2%) In summary, our data provided researchers an overview on S. aureus nasal carriage and antibiotic susceptibility profile of the community- isolated S. aureus in Vietnam. This would serve as valuable information on assessing risk of community-acquired S. aureus infections.


2020 ◽  
Vol 16 (3) ◽  
pp. 240-244 ◽  
Author(s):  
Nessrine Akasbi ◽  
Siar Nihad ◽  
Zoukal Sofia ◽  
El Kohen Khadija ◽  
Harzy Taoufik

Background: According to the new classification criteria developed by The Assessment of SpondyloArthritis International Society, patients with axial spondyloarthritis (axSpA) can be classified in 2 subgroups: Patients with radiographic axial spondyloarthritis: ankylosing spondylitis patients (AS) and those with non-radiographic axial spondyloarthritis (nr-axSpA). Objective: The aim of the present study is to describe and discuss the differences and similarities between the two subgroups. Patients and Methods: A cross-sectional study was conducted in a single rheumatology hospital in Morocco. These included patients diagnosed as having axial spondyloarthritis according to ASAS criteria 2010, during a period of 6 years. The AS and the nr-axSpA subgroups were compared for the various axSpA-related variables. Results: Of the 277 patients with a diagnosis of axial SpA who were included in this study, 160 had AS and 117 had nr-axSpA. AS and nr-ax-SpA shared a similar age at diagnosis, similar prevalence of low back pain, lumbar stiffness, extra-articular manifestations, BASDAI and BASFI. In the multivariate analysis, AS patients were mainly male with cervical stiffness, enthesitis, coxitis and high level of ESR (erythrocyte sedimentation rate). The females generally had a family history of SpA and arthritis and were associated to the nr-axSpA form in the univariate analysis. Conclusion: This was the first study to characterise patients with AS and nr-axSpA in Morocco. Consistent with other studies published, this study showed that patients with nr-axSpA and patients with AS shared a comparable degree of disease burden.


Sign in / Sign up

Export Citation Format

Share Document