Effect of Low-Frequency Electric Pulse Technique Combined with Carboprost Methylate Suppositories on Recovery of Gastrointestinal Function and Postoperative Complications of Patients with Scarred Uterus Undergoing Secondary Cesarean Section

The study aims to explore the effect of low-frequency electric pulse technique combined with carboprost methylate suppositories on recovery of gastrointestinal function and postoperative complications of patients with scarred uterus undergoing secondary cesarean section (C-section). The clinical data of 120 patients with scarred uterus undergoing secondary C-section treated in our hospital from February 2019 to February 2020 were retrospectively analyzed, and the patients were equally divided into experimental and control groups according to their admission order, where each group included 60 patients. After the operation, patients in the control group received routine nursing and conducted breastfeeding, and carboprost methylate suppositories were used for postoperative hemostasis. Those in the experimental group received low-frequency electric pulse technique for comprehensive treatment to compare their coagulation function indicators, recovery of gastrointestinal function, incidence rates of postoperative complications, and involution of uterus. No significant between-group differences in patients’ general information such as gestational weeks, gravidity, and number of times receiving C-section were observed ( P > 0.05 ). Compared with the control group after the operation, patients in the experimental group obtained significantly better coagulation function indicators ( P < 0.001 ) and presented better gastrointestinal function recovery ( P < 0.001 ), significantly lower incidence rates of postpartum hemorrhage, retention of urine, deep venous thrombosis of lower limb, rupture of uterus, and endometrial cavity fluid ( P < 0.05 ), and significantly better involution of uterus ( P < 0.001 ). In conclusion, combining low-frequency electric pulse technique with carboprost methylate suppositories can lower the incidence rates of postoperative complications for patients with scarred uterus undergoing secondary C-section, improve their coagulation function, promote the recovery of gastrointestinal function, and present the desirable involution of uterus, which should be promoted in practice.

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Analysis of Clinical Efficiency and Safety of Laparoscopic Anus-Conserving Operation for Ultralow Rectal Cancer

The American Surgeon ◽

10.1177/000313481908500533 ◽

2019 ◽

Vol 85 (5) ◽

pp. 539-548

Author(s):

Zhongkun Zuo ◽

Ke Ding ◽

Tenglong Tang ◽

Leiyi Zhang ◽

Weihui Peng ◽

...

Keyword(s):

Rectal Cancer ◽

Postoperative Complications ◽

Hospital Stay ◽

Incidence Rate ◽

Anal Sphincter ◽

Resection Margin ◽

Survival Rates ◽

Incidence Rates ◽

Control Group ◽

Experimental Group

To explore the efficiency and safety of laparoscopic anus-conserving operation for ultralow rectal cancer, we retrospectively reviewed 236 patients with ultralow rectal cancer who underwent laparoscopic anus-conserving operation (experimental group, n = 124) or conventional open surgery (control group, n = 112). Operation-related indexes, pathological results of mesentery, incidence rates of postoperative complications, anus preservation rates, anal sphincter controllability after surgery, and survival rates of the first, second, and third years after operation were compared between the two groups. The amount of intraoperative bleeding, first postoperative exhaust time, abdominal drainage, pain score, and hospital stay in the experimental group were significantly less than those in the control group ( P < 0.05). There were no significant differences in the postoperative circumferential resection margin, distal resection margin, number of dissected lymph nodes, successful resection rate, and quality of mesorectum between the two groups ( P > 0.05). The total incidence rate of postoperative complications, anal sphincter controllability, and survival rates after surgery were similar between the two groups ( P > 0.05). The anus preservation rate of the experimental group (84.7%) was significantly higher than that of the control group (69.6%) ( P < 0.05). Laparoscopic anus-conserving operation is effective and safe in treatment of patients with ultralow rectal cancer, which has advantages such as small trauma, less intra-operative bleeding, short hospital stay, rapid recovery, a low incidence rate of postoperative complications, and a high anus-preserving rate, so it is worthy of clinical application.

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Efficacy of infection control pathway in reducing postoperative infections in patients undergoing neurosurgery

The Journal of Infection in Developing Countries ◽

10.3855/jidc.11747 ◽

2020 ◽

Vol 14 (01) ◽

pp. 74-79

Author(s):

Chunli Dong ◽

Haozheng Yuan ◽

Renyan Xu ◽

Hui Zhang ◽

Lili He ◽

...

Keyword(s):

Postoperative Complications ◽

Infection Control ◽

Bacterial Count ◽

Incidence Rates ◽

Pathogen Transmission ◽

Control Group ◽

Postoperative Infections ◽

Post Surgery ◽

Equivalent Area ◽

Experimental Group

Introduction: The environment of the operating room (OR) is closely related to the postoperative complications of patients, and it is necessary to study, to what extent, the stringent management of the OR can reduce postoperative complications. Methodology: 426 patients who underwent surgery between January 2016 and December 2017 were selected from two class-100 laminar flow ORs of equivalent area, and were divided into an experimental group and a control group. Results: The experimental group had significantly lower total air-borne bacterial count in the OR than the control group 10 minutes before surgery (6.21 ± 4.14 vs. 11.58 ± 5.36 CFU/cm3), 10 minutes (15.67 ± 6.21 vs. 20.83 ± 5.78 CFU/cm3), 30 minutes (27.34 ± 8.18 vs. 39.56 ± 7.86 CFU/cm3) and 60 minutes (43.62 ± 7.66 vs. 51.63 ± 8.43 CFU/cm3) into surgery, and at the end of surgery (57.34 ± 7.67 vs. 69.33 ± 9.41 CFU/cm3) (all p < 0.05). The incidence rates of increased body temperature and leukocyte count 3 days post-surgery, and the duration of antibiotic therapy and hospital stay were significantly reduced in the experimental group compared to the control group (all p < 0.05). Furthermore, the total number of pathogens in the incision at 2 hours into surgery was also significantly lower in the experimental group than in the control group (p < 0.05). Conclusion: Stringent application of the infection control pathway is an efficacious measure for improving the air cleanliness of the neurosurgery OR, decreasing the incidence rates of postoperative complications and infection, as well as controlling pathogen transmission.

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Effects of Low-Frequency Cranial Electrostimulation on the Rest-Activity Rhythm and Salivary Cortisol in Alzheimer's Disease

Neurorehabilitation and Neural Repair ◽

10.1177/0888439003017002004 ◽

2003 ◽

Vol 17 (2) ◽

pp. 101-108 ◽

Cited By ~ 15

Author(s):

Erik Scherder ◽

Dirk Knol ◽

Eus van Someren ◽

Jan-Berend Deijen ◽

Rob Binnekade ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Activity Rhythm ◽

Low Frequency ◽

Control Group ◽

Positive Effects ◽

Alternative Research ◽

Positive Effect ◽

Experimental Group ◽

Rest Activity

Objective. In previous studies, cranial electrostimulation (CES) had positive effects on sleep in depressed patients and in patients with vascular dementia. The present study examined the effects of low-frequency CES on the rest-activity rhythm and cortisol levels of patients with probable Alzheimer's disease (AD). Method. It was hypothesised that a decreased level of cortisol would parallel a positive effect of low-frequency CES on nocturnal restlessness. Sixteen AD patients were randomly assigned to an experimental group (n = 8) or a control group (n = 8). The experimental group was treated with CES, whereas the control group received sham stimulation, for 30 minutes a day, during 6 weeks. The rest-activity rhythm was assessed by actigraphy. Cortisol was measured repeatedly in the saliva throughout the day by means of salivette tubes. Results. Low-frequency CES did not improve the rest-activity rhythm in AD patients. Moreover, both groups showed an increase instead of a decrease in the level of cortisol. Conclusions: These preliminary results suggest that low-frequency CES has no positive effect on the rest-activity rhythm in AD patients. An alternative research design with high-frequency CES in AD is discussed.

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Apparent growth paradox of Staphylococcus epidermidis in response to extremely low frequency electromagnetic radiation exposure

10.1101/2021.03.06.434218 ◽

2021 ◽

Author(s):

Dyaan Malik ◽

Esmeralda Pineda ◽

Deyvis Mejia Zambrana

Keyword(s):

Staphylococcus Epidermidis ◽

Colony Formation ◽

Human Microbiome ◽

Low Frequency ◽

Petri Dish ◽

Opportunistic Pathogen ◽

Inhibitory Effect ◽

Control Group ◽

Significant Difference ◽

Experimental Group

AbstractStaphylococcus epidermidis is a normal part of the human microbiome; however, it is an opportunistic pathogen and can cause infections when the delicate balance of this microbiome is disrupted. Furthermore, infections caused by this bacterium can be hard to treat as a result of antibiotic resistance and biofilm production. This experiment aimed to determine whether electromagnetic field radiation (ELF-EMF) could be a deterrent of bacterial growth, as an alternative treatment to antibiotics. A non-pathogenic strain of S. epidermidis was used for experimentation, which took place in a school laboratory setting. The experimental group was exposed to ELF-EMF, while the control group did not receive the ELF-EMF treatment. The number of bacterial colonies, represented as colony forming units (CFUs) and area of random colonies were calculated to determine the effect of this treatment. There was no dramatic difference of colony formation on days 0, 1, and 2 of the four day period of ELF-EMF exposure. However, colony formation for days 3 and 4 showed a significant difference between the control and the experimental groups, as the experimental group had a significantly higher CFU count than the control. The average CFU count for day 3 in the control group was 420.6 and 1,097.4 for the experimental group (p<0.0001, t=12.9803). On the final day of the experimentation (Day 4) the average CFU count for the control group was 424.6 and 896.4 for the experimental group (p<0.0001, t=5.8926). The area for five randomly chosen colonies from each petri dish was calculated on the fourth day of experimentation. The area for the experimental group was significantly lower than that control (p<0.0001, with t=6.8659). The average area for the control group was 1.3249 mm2 and a lower average of 0.6375mm2 for the experimental group. These results demonstrate that the ELF-EMF treatment had an inhibitory effect on the area growth of S. epidermidis, but not on the colony-forming ability of S. epidermidis. This suggests that ELF-EMF influences the means by which the bacterium S. epidermidis grows.

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Analysis of the Effect of Cluster Nursing in Postoperative Hypertensive Cerebral Hemorrhage

Journal of Healthcare Engineering ◽

10.1155/2021/3448979 ◽

2021 ◽

Vol 2021 ◽

pp. 1-5

Author(s):

Pingxia Zheng ◽

Jia Wang ◽

Yan Ma ◽

Jingjing Xu ◽

Qianping Zhu

Keyword(s):

Postoperative Complications ◽

Intracerebral Hemorrhage ◽

Treatment Compliance ◽

Nursing Intervention ◽

Control Group ◽

Total Incidence ◽

Hypertensive Intracerebral Hemorrhage ◽

And Control ◽

Experimental Group

Hypertensive intracerebral hemorrhage is a common condition in clinic. Due to the improvement of minimally invasive technology, its therapeutic effect is good, but there are still postoperative complications. The corresponding routine nursing intervention is not effective in the rehabilitation of postoperative patients with hypertensive intracerebral hemorrhage. In this paper, cluster nursing was applied to the treatment of postoperative patients with hypertensive intracerebral hemorrhage. For this purpose, a retrospective study or experiment was conducted on 150 patients with hypertensive intracerebral hemorrhage in the hospital specifically from January 2019 to December 2020. According to the nursing strategy, patients were divided into experimental (n = 75) and control groups (n = 75), respectively. The control group adopted routine nursing mode, whereas the experimental group adopted cluster nursing mode. The treatment compliance of patients in the experimental group was 86.67%, while that in the control group was 73.33% ( P < 0.05). The total incidence of postoperative complications in the experimental group was 3.2%, which was lower than 25% in the control group ( P < 0.05). The motor function score of the experimental group was better than that of the control group ( P < 0.05). The application of cluster nursing in postoperative patients with hypertensive intracerebral hemorrhage is feasible, and its nursing effect is significant, which can not only reduce the incidence of postoperative complications but also improve patients’ compliance and quality of life. It has good application value.

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Effectiveness of Low-Frequency Stimulation in Proprioceptive Neuromuscular Facilitation Techniques for Post-Ankle-Sprain Balance and Proprioception in Adults- a Randomized controlled trial

10.21203/rs.3.rs-29932/v1 ◽

2020 ◽

Author(s):

KHALID A ALAHMARI ◽

Paul Silvian Samuel ◽

Irshad Ahmad ◽

Ravi Shankar Reddy ◽

Jaya Shanker Tedla ◽

...

Keyword(s):

Physical Activity ◽

Range Of Motion ◽

Outcome Measures ◽

Ankle Sprain ◽

Low Frequency ◽

Control Group ◽

Significant Difference ◽

Proprioceptive Neuromuscular Facilitation ◽

Experimental Group

Abstract BackgroundStretching is an important part of post-ankle-sprain rehabilitation, as well as an effective exercise for improving general ankle-joint performance. But the combination of stretching alongside muscle stimulation has not yet been extensively studied. Therefore the purpose of the present research is to compare the baseline, post- and follow-up effects of the proprioceptive neuromuscular facilitation (PNF) stretching technique combined with transcutaneous electrical nerve stimulation (TENS), as compared against the effects of the PNF stretching technique alone.MethodsSixty subjects with lateral ankle sprains were selected and randomly allocated to three groups: Experimental Group One (EG 1), Experimental Group Two (EG 2), and the Control Group (CG). Subjects in EG 1 received the PNF stretching technique combined with TENS. Subjects in EG2 received the PNF stretching technique alone. Both experimental groups received these treatments for 4 weeks (4 days/week); follow-up assessments were administered in the third and fifth weeks. CG received no treatment; outcome measures alone were assessed. Outcome measures comprised pain, flexibility, proprioception, range of motion, muscle strength, physical activity, and balance. A mixed-model ANOVA was used to analyze the effects of time factors and groups on these outcome measures.ResultsThere was significant interaction (time and group), and the time effect for all the outcome measures (p < 0.05). Physical activity, dorsiflexion, and balance in the medial, lateral, anterolateral, and anteromedial directions did not show a significant difference between the groups. EG 1 showed significant improvement for all the outcome variables between pre- and post-treatment and follow-up when compared to the other groups.ConclusionsThe present study showed that a 12-session treatment program of 3 weeks’ duration that combines PNF stretching with low-frequency TENS for post-ankle sprain subjects, compared against PNF stretching alone, produced significant improvements in balance, proprioception, strength, and range of motion. The study also showed that the treatment effect was sustained even after treatment was ceased after the follow-up assessment in the fifth week.Trial Registration:Human Research Ethics Committee approval for the trial (approval no.: (ECM#2019-26)Clinical trial was also registered in the Clinical Trials Registry – ISRCTN 18013941

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Effect of Xiangbin Prescription in Gastrointestinal Function After Gynecological Abdominal Surgery: a Randomized Controlled Trial

10.21203/rs.3.rs-660427/v1 ◽

2021 ◽

Author(s):

Yuyan Wu ◽

Jinxuan Lin ◽

Haiping Zeng ◽

Yi Chen ◽

Zhiqiang Chen ◽

...

Keyword(s):

Postoperative Complications ◽

Abdominal Surgery ◽

Controlled Trial ◽

Controlled Study ◽

Chewing Gum ◽

Control Group ◽

Gastrointestinal Function ◽

Blank Control Group ◽

Randomized Controlled ◽

Significant Difference

Abstract Background: Recovery of gastrointestinal function after gynecological abdominal surgery is a major clinical problem. An effective intervention to promote the rapid recovery of gastrointestinal function postoperatively is lacking. This randomized trial investigated whether Xiangbin prescription (XBP) was feasible in terms of efficacy and safety on gastrointestinal function recovery in patients after gynecological abdominal surgery. Methods: A randomized controlled study was conducted, in which 190 patients with gynecological abdominal surgery who met the inclusion and exclusion criteria were enrolled. They were assigned randomly to XBP group, chewing gum group or blank control group, and respectively received the following treatments: took the XBP twice a day, chewed a piece of gum for about 15 minutes each 4 hours, or received conventional western basic treatment, starting on postoperative day 1 until defecation. Three groups were compared in terms of primary outcomes including the time of the first defecation and the time of the first flatus and secondary outcomes including the level of Ghrelin (GHRL) and the incidence of postoperative complications. Meanwhile, the safety of this trial was evaluated. Results: There was no statistical difference in baseline characteristics among the three groups. For the time of the first flatus, XBP group (22.33 ± 6.68 h) showed less time compared with the chewing gum group (23.06 ± 7.37 h), while it was shorter than that in the blank control group (25.86 ± 7.93 h) with significant difference (P < 0.05). As for the time of the first defecation, XBP group (38.65 ± 12.96 h) showed shorter time significantly compared with both the chewing gum group (47.29 ± 14.50 h) and the blank control group (54.01 ± 20.32 h) (P < 0.05). For the postoperative GHRL levels, XBP group was higher than that in the chewing gum group with no significant difference and had more significant improvement of the GHRL levels at postoperative day 3 compared with the blank control group (P < 0.05). For postoperative complications, XBP group had lower incidence than the other two groups but with no significant difference. For safety evaluations, no serious adverse events occurred in the three groups. Conclusions: XBP could promote the recovery of gastrointestinal function after gynecological abdominal surgery and it is overall safe. Trial registration: This trial was retrospectively registered by Chinese Clinical Trial Registry with the identifier number, ChiCTR1900026327, at September 30, 2019. http://www.chictr.org.cn/.

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Phase II trial of prophylactic hyperthermic intraperitoneal chemotherapy in patients with locally advanced gastric cancer after curative surgery

BMC Cancer ◽

10.1186/s12885-021-07925-2 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Biao Fan ◽

Zhaode Bu ◽

Ji Zhang ◽

Xianglong Zong ◽

Xin Ji ◽

...

Keyword(s):

Gastric Cancer ◽

Postoperative Complications ◽

Advanced Gastric Cancer ◽

Phase Ii Trial ◽

Locally Advanced ◽

Control Group ◽

Radical Gastrectomy ◽

Curative Surgery ◽

Locally Advanced Gastric Cancer ◽

Experimental Group

Abstract Background HIPEC is an emerging procedure to treat peritoneal metastasis of gastric cancer. Data about HIPEC in locally advanced gastric cancer is scarce. The purpose of this trial is to evaluate the safety and toxicity of prophylactic HIPEC with cisplatin for patients with locally advanced gastric cancer. Methods From March 2015 to November 2016, a prospective, randomized phase II trial was conducted. After radical gastrectomy, patients in the experimental group underwent HIPEC with cisplatin followed by adjuvant chemotherapy with SOX regime. Patients in the other group were treated with SOX regime alone. Postoperative complications and patient survival were compared. Results In total, 50 patients were eligible for analyses. No significant difference was found in the incidence of postoperative complications including anastomotic/intestinal leakage, liver dysfunction, bone marrow suppression, wound infection and ileus (P > 0.05). Mean duration of hospitalization after radical gastrectomy was 11.7 days. 12.2 days in experimental group and 10.8 days in control group respectively (P = 0.255). The percentage of patients with elevated tumor markers was 12.1% in experimental group, which was significantly lower than 41.2% in control group (P = 0.02). 3-year RFS of patients who treated with or without prophylactic HIPEC were 84.8 and 88.2% respectively (P = 0.986). In the multivariate analysis, pathological T stage was the only independent risk factor for the RFS of patients (P = 0.012, HR =15.071). Conclusion Additional intraoperative HIPEC with cisplatin did not increase postoperative complications for locally advanced gastric cancer after curative surgery. Prophylactic HIPEC with cisplatin was safe and tolerable, while it did not reduce the risk of peritoneal recurrence in this trial, supporting further studies to validate the efficacy of it. Trial registration Chinese Clinical Trial Registry, ChiCTR2000038331. Registered 18 September 2020 - Retrospectively registered, http://www.chictr.org.cn/showproj.aspx?proj=59692.

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Effect of Augmentatory Repetitive Transcranial Magnetic Stimulation on Auditory Hallucinations in Schizophrenia: Randomized Controlled Study

Australian & New Zealand Journal of Psychiatry ◽

10.1080/00048670802653315 ◽

2009 ◽

Vol 43 (4) ◽

pp. 386-392 ◽

Cited By ~ 15

Author(s):

Dhruv Bagati ◽

Shamshul Haque Nizamie ◽

Ravi Prakash

Keyword(s):

Transcranial Magnetic Stimulation ◽

Magnetic Stimulation ◽

Repetitive Transcranial Magnetic Stimulation ◽

Low Frequency ◽

Auditory Hallucinations ◽

Controlled Study ◽

Control Group ◽

Antipsychotic Treatment ◽

Experimental Group ◽

Low Frequency Rtms

Objective: Auditory hallucinations are a characteristic symptom of schizophrenia and are usually resistant to treatment. The present study was conducted to further support the findings that repetitive transcranial magnetic stimulation (rTMS) reduces auditory hallucinations, and to evaluate the effect of low-frequency rTMS on auditory hallucinations in schizophrenia. Methods: Forty schizophrenia patients were included in the study. Patients were randomized to control or experimental group. Low-frequency rTMS (1 Hz, 90% motor threshold) was applied to the left temporoparietal cortex of patients in the experimental group for 10 days following the standard guidelines as an addition to antipsychotic treatment. The control group received only antipsychotics. The changes in the psychopathology scores for the auditory hallucinations were recorded using auditory hallucination recording scale. The rater was blind to the intervention procedure. Results: A significant improvement was found in auditory hallucinations in the experimental group as compared to the control group. Conclusion: Left temporoparietal rTMS warrants further study as an intervention for auditory hallucinations. Data suggest that this intervention selectively alters neurobiological factors determining frequency of these hallucinations.

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Effects of visual search task on attentional bias and stress response under pressure

Work ◽

10.3233/wor-213509 ◽

2021 ◽

pp. 1-11

Author(s):

Yonghui Jin ◽

Jun He

Keyword(s):

Visual Search ◽

Stress Response ◽

Search Task ◽

Visual Search Task ◽

Low Frequency ◽

Attention Bias ◽

The Self ◽

Control Group ◽

Before And After ◽

Experimental Group

BACKGROUND: it has always been a problem for athletes that their performance is out of order due to pressure in major competitions. The change of attention pattern and the emergence of stress response (SR) caused by negative affect (NA)are the direct reasons for the greater impact on the performance of athletes. It is a hot topic to explore how to improve attention bias (AB) and SR of athletes in stressful situations. OBJECTIVE: the study aimed to analyze the improvement effect of visual search task (VST) training on AB and SR of athletes under pressure situations. METHODS: 62 male basketball players with national level 2 or above of Shenyang sports institute were divided into experimental group (EG) and control group (CG). Visual search task training program was used in the EG (happy, sad, disgusted, neutral faces) and sham training program was used in the CG (all faces with neutral expression) for two months. Under the stress situation, attention behavior of all subjects before and after training was tested. Physiological coherence and autonomic balance system were used to record heart rate variability synchronously. Parallel frequency domain analysis was divided into very low frequency band (VLF), low frequency (LF), high frequency (HF) and total spectrum (TP). The normalized treatment obtained indexes such as HFnorm, LFnorm, and LF/HF. The e-prime 2.0 software was adopted to obtain the attention bias score. The Positive and Negative Affect Scale (PANAS) and the self - rating stress scale were adopted for evaluation before and after training. RESULTS: the self-rating pressure in the two groups was lower than that before the training, and the pressure in the experimental group was lower than that in the control group (P < 0.05). After training, the positive emotion of the experimental group was higher than that of the control group, and the EG was lower than that of the CG (P < 0.05). After training, the score of attention bias of happy and neutral faces in the EG was higher than that of theCG, while the score of attention bias of sad and disgusted faces was lower than that of the CG (P < 0.05). After training, LF/HF and LFnorm in the EG were lower than those in the CG, and HFnorm was higher than those in the CG (P < 0.05). CONCLUSIONS: the training of visual search task can effectively improve the athletes’ PA and AB of positive information, reduce the attention bias of negative information and psychological pressure, and relieve theSR.

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