Analysis of Clinical Efficiency and Safety of Laparoscopic Anus-Conserving Operation for Ultralow Rectal Cancer

To explore the efficiency and safety of laparoscopic anus-conserving operation for ultralow rectal cancer, we retrospectively reviewed 236 patients with ultralow rectal cancer who underwent laparoscopic anus-conserving operation (experimental group, n = 124) or conventional open surgery (control group, n = 112). Operation-related indexes, pathological results of mesentery, incidence rates of postoperative complications, anus preservation rates, anal sphincter controllability after surgery, and survival rates of the first, second, and third years after operation were compared between the two groups. The amount of intraoperative bleeding, first postoperative exhaust time, abdominal drainage, pain score, and hospital stay in the experimental group were significantly less than those in the control group ( P < 0.05). There were no significant differences in the postoperative circumferential resection margin, distal resection margin, number of dissected lymph nodes, successful resection rate, and quality of mesorectum between the two groups ( P > 0.05). The total incidence rate of postoperative complications, anal sphincter controllability, and survival rates after surgery were similar between the two groups ( P > 0.05). The anus preservation rate of the experimental group (84.7%) was significantly higher than that of the control group (69.6%) ( P < 0.05). Laparoscopic anus-conserving operation is effective and safe in treatment of patients with ultralow rectal cancer, which has advantages such as small trauma, less intra-operative bleeding, short hospital stay, rapid recovery, a low incidence rate of postoperative complications, and a high anus-preserving rate, so it is worthy of clinical application.

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Short and long-term effects of two different surgery approaches for remnant gastric cancer.

Journal of Clinical Oncology ◽

10.1200/jco.2017.35.4_suppl.180 ◽

2017 ◽

Vol 35 (4_suppl) ◽

pp. 180-180

Author(s):

Lin Chen ◽

Yingkun Ren ◽

Yajie Zheng

Keyword(s):

Gastric Cancer ◽

Hospital Stay ◽

Radical Surgery ◽

Survival Rates ◽

Control Group ◽

Remnant Gastric Cancer ◽

Long Term Effects ◽

Average Hospital ◽

The Mean ◽

Experimental Group

180 Background: To evaluate the short- and long-term effects of two different surgery approaches for remnant gastric cancer after distal gastrectomy. Methods: Clinical data of 48 remnant gastric cancer patients were collected retrospectively from the period of January 1st 2010 to December 31st 2012 in this matched-pair study. Twenty four patients in the experimental group underwent radical surgery in antegrade approach (starting from the esophagus to the gastrointestinal anastomosis), another 24 matched patients in the control group underwent radical surgery in retrograde approach (starting from the gastrointestinal anastomosis to the esophagus). Constants in the study were patient age, the operating surgeon, Borrmann type, TNM stage and operation range. Pearsonχ2 testor t-test were used to compare the clinicopathological characteristics between the two groups. Survival rates of 1- and 3-years were analyzed with Kaplan-Meier survival curve and compared with Log-rank test. Results: The 48 patients were treated successfully without any mortality during their hospital stay. The mean operative time and bleeding volume in the experimental and control groups were (126.6±5.7) min and (154.1±23.9)ml , and (168.3±11.7) min and (180.8±15.0)ml respectively. The difference in the mean operative times (t = -3.089, P = 0.005) and the mean bleeding volumes (t = -3.269, P = 0.004) were statistically significant. The average hospital stay after surgery and the average number of lymph nodes resected were (9.5±0.9) days and 18.7±1.6 in the experimental group,(9.2±0.8) day and 17.4±1.4 in the control group. There was no statistical differences between the two groups in terms of the average hospital stay (t = 0.692, P = 0.496) and the average number of resected lymph nodes (t = 2.101, P = 0.247). The overall 1- year and 3-years survival rates were 75%, 49% in the experimental group and 67%, 35% in the control group. There was also no statistical difference in the 1-year (P = 0.745) and 3-years (P = 0.878) survival rates. Conclusions: Compared with retrograde approach, performing radical surgery in antegrade way for remnant gastric cancer patients can shorten the operation time, reduce blood loss and simplify the operation procedure.

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Efficacy of infection control pathway in reducing postoperative infections in patients undergoing neurosurgery

The Journal of Infection in Developing Countries ◽

10.3855/jidc.11747 ◽

2020 ◽

Vol 14 (01) ◽

pp. 74-79

Author(s):

Chunli Dong ◽

Haozheng Yuan ◽

Renyan Xu ◽

Hui Zhang ◽

Lili He ◽

...

Keyword(s):

Postoperative Complications ◽

Infection Control ◽

Bacterial Count ◽

Incidence Rates ◽

Pathogen Transmission ◽

Control Group ◽

Postoperative Infections ◽

Post Surgery ◽

Equivalent Area ◽

Experimental Group

Introduction: The environment of the operating room (OR) is closely related to the postoperative complications of patients, and it is necessary to study, to what extent, the stringent management of the OR can reduce postoperative complications. Methodology: 426 patients who underwent surgery between January 2016 and December 2017 were selected from two class-100 laminar flow ORs of equivalent area, and were divided into an experimental group and a control group. Results: The experimental group had significantly lower total air-borne bacterial count in the OR than the control group 10 minutes before surgery (6.21 ± 4.14 vs. 11.58 ± 5.36 CFU/cm3), 10 minutes (15.67 ± 6.21 vs. 20.83 ± 5.78 CFU/cm3), 30 minutes (27.34 ± 8.18 vs. 39.56 ± 7.86 CFU/cm3) and 60 minutes (43.62 ± 7.66 vs. 51.63 ± 8.43 CFU/cm3) into surgery, and at the end of surgery (57.34 ± 7.67 vs. 69.33 ± 9.41 CFU/cm3) (all p < 0.05). The incidence rates of increased body temperature and leukocyte count 3 days post-surgery, and the duration of antibiotic therapy and hospital stay were significantly reduced in the experimental group compared to the control group (all p < 0.05). Furthermore, the total number of pathogens in the incision at 2 hours into surgery was also significantly lower in the experimental group than in the control group (p < 0.05). Conclusion: Stringent application of the infection control pathway is an efficacious measure for improving the air cleanliness of the neurosurgery OR, decreasing the incidence rates of postoperative complications and infection, as well as controlling pathogen transmission.

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Effect of Low-Frequency Electric Pulse Technique Combined with Carboprost Methylate Suppositories on Recovery of Gastrointestinal Function and Postoperative Complications of Patients with Scarred Uterus Undergoing Secondary Cesarean Section

Journal of Healthcare Engineering ◽

10.1155/2021/6143421 ◽

2021 ◽

Vol 2021 ◽

pp. 1-9

Author(s):

Jinling Yan ◽

Yongli Liu ◽

Ruifen Jiao ◽

Meixiang Li ◽

Liqin Zhao

Keyword(s):

Postoperative Complications ◽

Electric Pulse ◽

Low Frequency ◽

Incidence Rates ◽

Control Group ◽

Gastrointestinal Function ◽

Pulse Technique ◽

Coagulation Function ◽

Scarred Uterus ◽

Experimental Group

The study aims to explore the effect of low-frequency electric pulse technique combined with carboprost methylate suppositories on recovery of gastrointestinal function and postoperative complications of patients with scarred uterus undergoing secondary cesarean section (C-section). The clinical data of 120 patients with scarred uterus undergoing secondary C-section treated in our hospital from February 2019 to February 2020 were retrospectively analyzed, and the patients were equally divided into experimental and control groups according to their admission order, where each group included 60 patients. After the operation, patients in the control group received routine nursing and conducted breastfeeding, and carboprost methylate suppositories were used for postoperative hemostasis. Those in the experimental group received low-frequency electric pulse technique for comprehensive treatment to compare their coagulation function indicators, recovery of gastrointestinal function, incidence rates of postoperative complications, and involution of uterus. No significant between-group differences in patients’ general information such as gestational weeks, gravidity, and number of times receiving C-section were observed ( P > 0.05 ). Compared with the control group after the operation, patients in the experimental group obtained significantly better coagulation function indicators ( P < 0.001 ) and presented better gastrointestinal function recovery ( P < 0.001 ), significantly lower incidence rates of postpartum hemorrhage, retention of urine, deep venous thrombosis of lower limb, rupture of uterus, and endometrial cavity fluid ( P < 0.05 ), and significantly better involution of uterus ( P < 0.001 ). In conclusion, combining low-frequency electric pulse technique with carboprost methylate suppositories can lower the incidence rates of postoperative complications for patients with scarred uterus undergoing secondary C-section, improve their coagulation function, promote the recovery of gastrointestinal function, and present the desirable involution of uterus, which should be promoted in practice.

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Nationwide trends in the incidence of orbital lymphoma from 1999 to 2016 in South Korea

British Journal of Ophthalmology ◽

10.1136/bjophthalmol-2020-316796 ◽

2020 ◽

pp. bjophthalmol-2020-316796

Author(s):

Su Kyung Jung ◽

Jiwon Lim ◽

Suk Woo Yang ◽

Young-Joo Won

Keyword(s):

South Korea ◽

B Cell ◽

Incidence Rate ◽

Cell Lymphoma ◽

Survival Rates ◽

B Cell Lymphoma ◽

Population Based ◽

Incidence Rates ◽

Annual Percent Change ◽

Orbital Lymphoma

Background/AimsLymphomas are the most frequent neoplasm of the orbit. However, the epidemiology of orbital lymphomas is not well reported. This study aimed to provide a population-based report on the epidemiology of orbital lymphomas and measure the trends in the incidence of orbital lymphoma cancer in South Korea.MethodsNationwide cancer incidence data from 1999 to 2016 were obtained from the Korea Central Cancer Registry. Age-standardised incidence rates and annual percent changes were calculated according to sex and histological types. The analysis according to the Surveillance, Epidemiology, and End Results summary stage classifications was performed from 2006 to 2016. Survival rates were estimated for cases diagnosed from 1999 to 2016.ResultsA total of 630 patients (median age: 54 years) with orbital lymphoma in the orbital soft tissue were included in this study. The age-standardised incidence rates increased from 0.03 to 0.08 per 100 000 individuals between 1999 and 2016, with an annual percent change of 6.61%. The most common histopathological type of orbital lymphoma was extra marginal zone B cell lymphoma, accounting for 82.2% of all orbital lymphomas during 1999–2016, followed by diffuse large B cell lymphoma (9.2%). Five-year, 10-year and 15-year overall survival (OS) of orbital lymphoma was 90.8%, 83.8% and 75.8%, respectively. OS showed a significant decrease as age increased and no significant differences between men and women.ConclusionThe incidence rate of orbital lymphoma is very low in South Korea. However, the incidence rate has increased over the past years. Orbital lymphomas have a worse prognosis as age increases.

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Influence of an Implant Fixture Including a Freely Removable Micro-Locking Implant Prosthesis on Peri-Implant Tissues and Implant Prostheses: A Prospective Clinical Study

Journal of Clinical Medicine ◽

10.3390/jcm10153321 ◽

2021 ◽

Vol 10 (15) ◽

pp. 3321

Author(s):

Young-Gun Shin ◽

Won-Tak Cho ◽

Ho-Kyung Lim ◽

Su-Hyun Hwang ◽

Ji-Hyeon Bae ◽

...

Keyword(s):

Survival Rates ◽

Treatment Method ◽

Control Group ◽

Prospective Clinical Study ◽

Food Impaction ◽

Radiographic Findings ◽

The One ◽

Implant System ◽

Experimental Group ◽

Observation Period

This prospective study was undertaken to evaluate the clinical usefulness of a newly developed one-piece, screw-free, and micro-locking implant system, which was designed to overcome the shortcomings of the existing implant systems. Thirty-eight patients were recruited and randomly and equally assigned to an experimental group (micro-locking one-piece fixture, MLF; n = 19) or a control group (micro-locking abutment, MLA). Cumulative implant survival rates, marginal bone resorptions, probing depths, plaque indices, bleeding indices, and complications were obtained by using clinical and radiographic findings at 6 months and 12 months after prosthesis placement. Complications that occurred multiple times for single implants were counted. During the 12 month observation period, survival rates were 100% in both groups. No significant intergroup differences were observed for marginal bone resorption, probe depth, or bleeding index. However, mean plaque index was significantly lower in the MLF group at 12 months (p < 0.05). During the 12-month observation period, food impaction (26.3%) was the maincomplication in the MLF group and screw loosening (5.3%), prosthesis detachment (5.3%), and food impaction (5.3%) were observed in the MLA group. The results of this study suggest that the one-piece micro-locking implant system offers a predictable treatment method.

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Clinical Efficacy of Fuzheng Guben Anticancer Decoction Combined with Taxol in Treating Ovarian Carcinoma and Its Effect on Complication Incidence

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2021/2782875 ◽

2021 ◽

Vol 2021 ◽

pp. 1-6

Author(s):

Pinger Li ◽

Yinmei Lou

Keyword(s):

Ovarian Carcinoma ◽

Incidence Rate ◽

Clinical Efficacy ◽

Remission Rate ◽

General Information ◽

Group Differences ◽

Control Group ◽

Clinical Value ◽

The Mean ◽

Experimental Group

Objective. To investigate the clinical value of Fuzheng Guben anticancer decoction combined with taxol in treating ovarian carcinoma (OC). Methods. The medical records of 80 OC patients treated in the First People’s Hospital of Fuyang Hangzhou (January 2018–January 2021) were retrospectively analyzed, and the patients were split into the control group and the experimental group according to the treatment regimen, with 40 cases each. Those in the control group accepted the taxol chemotherapy, and on this basis, those in the experimental group took the Fuzheng Guben anticancer decoction, so as to compare its clinical efficacy and complication incidence. Results. No statistical between-group differences in patients’ general information were observed P > 0.05 ; compared with the control group, the disease objective remission rate of the experimental group was greatly higher P < 0.05 ; before and after treatment, the changes in CD8+ were not significant, indicating no statistically significant between-group differences P > 0.05 , and after treatment, CD3+, CD4+, and CD4+/CD8+ were obviously higher than before and were obviously higher in the experimental group than in the control group P < 0.05 ; after treatment, the CA125, CA199, and CEA levels were obviously lower than before and were significantly lower in the experimental group than in the control group P < 0.05 ; the mean survival of the experimental group was significantly higher than that of the control group (19.80 ± 5.84 vs. 14.075 ± 5.12 months, P < 0.05 ); and between the two groups, the incidence rate of adverse reactions of the experimental group was remarkably lower P < 0.05 . Conclusion. On the basis of taxol chemotherapy, jointly applying Fuzheng Guben anticancer decoction can significantly improve the clinical efficacy of OC, help to improve patients’ immune function, lower the complication incidence rate, and prolong the mean survival.

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Optimization of Esophageal Ultrasound under Artificial Fish Swarm Algorithm and Its Adoption in Treatment of Ventricular Septal Defect

Scientific Programming ◽

10.1155/2021/7126251 ◽

2021 ◽

Vol 2021 ◽

pp. 1-9

Author(s):

Zhi Li ◽

Guihe Chen ◽

Feng Wang

Keyword(s):

Ventricular Septal Defect ◽

Hospital Stay ◽

Septal Defect ◽

Average Length ◽

Length Of Hospital Stay ◽

Control Group ◽

Artificial Fish Swarm Algorithm ◽

Artificial Fish Swarm ◽

Swarm Algorithm ◽

Experimental Group

This work was aimed at exploring the adoption value of the optimized and upgraded esophageal ultrasound in the treatment of patients with ventricular septal defect (VSD) by artificial fish swarm algorithm. A model was built based on artificial fish swarm algorithm. A random ultrasonic optical signal in the database was decomposed several times and sparsity was optimized to complete partial optimization, which was then extended to global optimization. A total of 100 patients with ventricular septal defect were divided into control group who underwent cardiopulmonary bypass under the guidance of three-dimensional thoracic ultrasound and experimental group of ventricular septal defect occlusion under the guidance of esophageal ultrasound based on artificial fish swarm algorithm. The results showed that the number of successful cases in the experimental group was 12 cases of perimembranous type, 10 cases of septal type, 7 cases of simple membranous type, 13 cases of muscular type, 4 cases of subdry type, and 2 cases of ridge type. The average length of operation after surgery was 70.65 minutes, the average length of ventilator ventilation was 125.8 minutes, and the average length of intensive care unit was 377.9 minutes. The average length of hospital stay after surgery was 5.6 days, and the average total length of hospital stay was 8.2 days, which were better than the control group in many aspects, with statistical significance ( P < 0.05 ). In short, the artificial fish swarm algorithm for esophageal ultrasound-guided ventricular septal defect closure had short operation time and good postoperative effect, which was of high application value in the clinical treatment of patients with ventricular septal defect.

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Impact of Psychotherapeutic Support for Patients With Gastrointestinal Cancer Undergoing Surgery: 10-Year Survival Results of a Randomized Trial

Journal of Clinical Oncology ◽

10.1200/jco.2006.08.2883 ◽

2007 ◽

Vol 25 (19) ◽

pp. 2702-2708 ◽

Cited By ~ 75

Author(s):

Thomas Küchler ◽

Beate Bestmann ◽

Stefanie Rappat ◽

Doris Henne-Bruns ◽

Sharon Wood-Dauphinee

Keyword(s):

Colorectal Cancer ◽

Hospital Stay ◽

Gastrointestinal Cancer ◽

Cox Regression ◽

Medical Psychology ◽

Control Group ◽

Term Survival ◽

Formal Program ◽

The Impact ◽

Experimental Group

Purpose The impact of psychotherapeutic support on survival for patients with gastrointestinal cancer undergoing surgery was studied. Patients and Methods A randomized controlled trial was conducted in cooperation with the Departments of General Surgery and Medical Psychology, University Hospital of Hamburg, Germany, from January 1991 to January 1993. Consenting patients (N = 271) with a preliminary diagnosis of cancer of the esophagus, stomach, liver/gallbladder, pancreas, or colon/rectum were stratified by sex and randomly assigned to a control group that received standard care as provided on the surgical wards, or to an experimental group that received formal psychotherapeutic support in addition to routine care during the hospital stay. From June 2003 to December 2003, the 10-year follow-up was conducted. Survival status for all patients was determined from our own records and from three external sources: the Hamburg cancer registry, family doctors, and the general citizen registration offices. Results Kaplan-Meier survival curves demonstrated better survival for the experimental group than the control group. The unadjusted significance level for group differences was P = .0006 for survival to 10 years. Cox regression models that took TNM staging or the residual tumor classification and tumor site into account also found significant differences at 10 years. Secondary analyses found that differences in favor of the experimental group occurred in patients with stomach, pancreatic, primary liver, or colorectal cancer. Conclusion The results of this study indicate that patients with gastrointestinal cancer, who undergo surgery for stomach, pancreatic, primary liver, or colorectal cancer, benefit from a formal program of psychotherapeutic support during the inpatient hospital stay in terms of long-term survival.

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Preliminary Study of Transforaminal Endoscope in the Treatment of Spinal Metastasis

Proceedings of Anticancer Research ◽

10.26689/par.v4i2.1200 ◽

2020 ◽

Vol 4 (2) ◽

Author(s):

Daiqi Guo ◽

Tenghui Zeng

Keyword(s):

Hospital Stay ◽

Spinal Metastases ◽

Length Of Hospital Stay ◽

Control Group ◽

Activity Time ◽

Incision Length ◽

Drainage Volume ◽

Surgical Methods ◽

Postoperative Drainage ◽

Experimental Group

Objective: To investigate the therapeutic effect of transforaminal endoscope in patients with spinal metastases. Methods: Clinical data of 28 patients with spinal metastases admitted to our hospital from May 2015 to May 2019 were retrospectively collected. According to different surgical methods, they were divided into control group (20 cases) and experimental group (8 cases), among which control group was treated with traditional open palliative decompression, while the experimental group was treated with transforaminal endoscopic decompression. The surgery and recovery indicators were compared between the two groups, including surgery time, incision length, postoperative drainage volume, out of bed activity time, length of hospital stay, the Japanese Orthopaedic Association (JOA) scores of 7 days after surgery, pain degree, complications (wound infection, transient reduction of muscle strength, hypoproteinemia with wound drainage and delayed healing), and activity of daily living. Results: The surgery time, incision length, postoperative drainage volume, out of bed activity time, and postoperative length of hospital stay of the experimental group were all less than those of the control group, and the JOA score of 7 days after surgery was higher than that of the control group, showing statistically significant differences (P < 0.05). VAS scores of the experimental group on the day 1 and day 7 after surgery were lower than those of the control group, with statistically significant differences (P < 0.05). The incidence of complications in the experimental group was slightly lower than that in the control group, but the difference was not significant (P > 0.05). Conclusions: Transforaminal endoscope used in suitable patients with spinal metastases can greatly reduce the incision length, soft tissue and bone tissue damages, and postoperative drainage, promote early mobilization and early discharge, and reduce a series of complications due to hemorrhage and hypoproteinemia, which has a better early clinical effect in comparison with the traditional open palliative decompression.

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The Psychological Effect of Forming WeChat Groups Between Medical Staff and Patients With COVID-19

Frontiers in Public Health ◽

10.3389/fpubh.2021.586465 ◽

2021 ◽

Vol 9 ◽

Author(s):

Li-Ping Yuan ◽

Zheng-Hao Yu ◽

Xian-Cui Zhang ◽

Wei Zhang ◽

Ling-Li Jin ◽

...

Keyword(s):

Hospital Stay ◽

Medical Staff ◽

Psychological Intervention ◽

Depression Scale ◽

Basic Unit ◽

Control Group ◽

Self Evaluation ◽

The Difference ◽

And Control ◽

Experimental Group

Background: This study was conducted in order to explore the effect of psychological intervention based on the use of WeChat with coronavirus disease 2019 (COVID-19) patients.Methods: A total of 65 patients with COVID-19, from two wards, were divided into an experimental group and a control group with the ward as the basic unit. Communication concerning routine treatment and nursing was established between the medical staff and patients in the experimental group via WeChat groups. Within 48 h of admission, at 7 days, and on discharge, all 65 patients completed two self-evaluation questionnaires: the Positive and Negative Affect Schedule (PANAS) and the Hospital Anxiety and Depression Scale (HADS). Hospital stay statistics and a satisfaction survey on discharge were also collated for both groups of patients.Results: The PANAS scores of the experimental group were 26.61 ± 7.99 points on admission, 20.81 ± 5.48 points at 7 days, and 19.58 ± 6.61 points on discharge (P < 0.05). The scores of HADS in the experimental group were 27.74 ± 9.35 points on admission, 12.19 ± 1.92 points at 7 days, and 11.71 ± 3.64 points on discharge (P < 0.05). The differences in the PANS and HADS scores between the experimental and control groups at 7 days and on discharge were statistically significant. The discharge satisfaction ratings of the two groups of patients were 99.87 ± 0.34 and 98.68 ± 1.09 points, the difference being statistically significant (t = 5.827, P < 0.05).Conclusion: Establishing WeChat groups between medical staff and patients with COVID-19 and building a bridge for better communication improved patients' positive mentality and their compliance with doctors, shortened their hospital stay, and promoted their recovery.

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