Early-Term Complications after Carotid Endarterectomy and Their Risk Factors: Eight-Year Employment of Local Treatment Protocol of a Russian High-Volume Center

2020 ◽  
pp. 1-12
Author(s):  
Denis Skrypnik ◽  
Roman Vinogradov ◽  
Coral Falco ◽  
Alexander Baryshev ◽  
Vladimir Porhanov
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Myocardial Infarction ◽  
Carotid Endarterectomy ◽  
Retrospective Analysis ◽  
Independent Predictor ◽  
Univariate Analysis ◽  
Local Treatment ◽  
Data Set ◽  
History Of

<b><i>Background:</i></b> More than 20,000 carotid endarterectomies are performed annually in the Russian Federation. Until now, no studies based on the national carotid data set have been published. The objectives of this study were to evaluate early outcomes after carotid endarterectomy and to identify potential risk factors for major adverse cardiovascular events. <b><i>Materials and Methods:</i></b> The retrospective analysis was based on data recorded in a single-center registry, including all carotid endarterectomies performed between 2010 and 2017. A univariate analysis was used to identify the risk factors for perioperative mortality, and predictors of stroke were determined using a multivariate logistic regression model. <b><i>Results:</i></b> Data from 1,832 patients with a mean age of 64.1 ± 7.6 years were analyzed. The combined in-hospital mortality was 0.65% (12/1,832). The rate of stroke was 0.7% (13/1,832), and the rate of myocardial infarction was 1.1% (20/1,832). The 30-day stroke-free survival was 99%. A history of stroke (<i>p</i> = 0.02) and chronic obstructive pulmonary disease (COPD; <i>p</i> = 0.0001) were found to be predictive of a lethal stroke. Previous myocardial infarction (<i>p</i> = 0.0001), an advanced stage of congestive heart failure (<i>p</i> = 0.0001), and angina pectoris (<i>p</i> = 0.01) were associated with cardiac-related mortality. Moreover, diabetes mellitus (<i>p</i> = 0.03), COPD (<i>p</i> = 0.0001), and carotid calcinosis (<i>p</i> = 0.006) increased the risk of poor survival due to myocardial infarction. The mean duration of clamping was found to be an independent predictor of any perioperative stroke (OR = 1.109; 95% CI 1.052–1.129; <i>p</i> &#x3c; 0.0001). <b><i>Conclusions:</i></b> The present retrospective analysis of the local carotid surgery register showed appropriate outcomes after CEA regarding the cumulative incidence of MACE, which is comparable to previously published international register data. A previous history of stroke, myocardial infarction, COPD, a prolonged clamping time during CEA, and diabetes mellitus were found to be factors of high-risk for cardiovascular mortality. A prolonged clamping was identified as an independent predictor of any stroke.

scholarly journals Incidence and Risk Factors for Bilateral Nephrolithiasis: A Large Case-retrospective Study

2021 ◽  
Author(s):  
Xiong Yang ◽  
Zhi Li ◽  
Shiyong Qi ◽  
Linguo Xie ◽  
Qiduo Shi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Multivariate Analysis ◽  
Kidney Stones ◽  
Statistical Significance ◽  
Univariate Analysis ◽  
Renal Stones ◽  
Urinary Stones ◽  
Preoperative Imaging ◽  
History Of

Abstract To determine the incidence and risk factors of bilateral kidney stones. Utilized the retrospective analysis method on demographic characteristics and clinical data of patients with renal stones in the Second Hospital of Tianjin Medical University. Grouped patients into unilateral and bilateral renal stones according to preoperative imaging and ultrasound examination. Univariate and multivariate analysis methods were used to evaluate the factors that may cause bilateral stones. The study included 7587 patients with kidney stones in total, of whom 4983 had unilateral kidney stones (including 2719 left stones and 2264 right stones), and 2604 had bilateral kidney stones (34.3%). By comparing the unilateral stones group with the bilateral stones group, the univariate analysis demonstrated that weight, body mass index (BMI), history of nephrolithiasis, diabetes mellitus (DM), hypertension, gout, and the maximal stone diameter had statistical significance. Binary logistic regression multivariate analysis demonstrated that BMI, history of nephrolithiasis, diabetes mellitus, hypertension, gout, and the maximal stone diameter were independent risk factors for bilateral urinary stones. This study shows that 34.3% of patients with kidney stones were diagnosed as having bilateral kidney stones; BMI and the maximal stone diameter are positively correlated with the incidence of bilateral kidney stones; Patients with a history of nephrolithiasis, diabetes, hypertension, and gout have a significantly higher risk of having bilateral kidney stones.

Factors associated with diagnosis and operability of chronic thromboembolic pulmonary hypertension

2013 ◽  
Vol 110 (07) ◽  
pp. 83-91 ◽  
Author(s):  
Gérald Simonneau ◽  
Joanna Pepke-Zaba ◽  
Eckhard Mayer ◽  
David Ambrož ◽  
Isabel Blanco ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Pulmonary Hypertension ◽  
Venous Thromboembolism ◽  
Univariate Analysis ◽  
Chronic Thromboembolic Pulmonary Hypertension ◽  
Factors Associated ◽  
Thromboembolic Pulmonary Hypertension ◽  
History Of ◽  
Acute Venous Thromboembolism

SummaryChronic thromboembolic pulmonary hypertension (CTEPH) and idiopathic pulmonary hypertension (IPAH) share a similar clinical presentation, and a differential diagnosis requires a thorough workup. Once CTEPH is confirmed, patients who can be safely operated have to be identified. We investigated risk factors associated with CTEPH and IPAH, and the criteria for the selection of operable CTEPH patients. This case-control study included 436 consecutive patients with CTEPH and 158 with IPAH in eight European centres, between 2006 and 2010. Conditions identified as risk factors for CTEPH included history of acute venous thromboembolism (p < 0.0001), large size of previous pulmonary embolism (p = 0.0040 in univariate analysis), blood groups non-O (p < 0.0001 in univariate analysis), and older age (p = 0.0198), whereas diabetes mellitus (p = 0.0006), female gender (p = 0.0197) and higher mean pulmonary artery pressure (p = 0.0103) were associated with increased likelihood for an IPAH diagnosis. Operability of CTEPH patients was associated with younger age (p = 0.0108), proximal lesions (p ≤ 0.0001), and pulmonary vascular resistance below 1200 dyn.s.cm-5 (p = 0.0080). Non-operable CTEPH patients tended to be less differentiable from IPAH patients by risk factor analysis than operable patients. This study confirmed the association of CTEPH with history of acute venous thromboembolism and blood groups non-O, and identified diabetes mellitus and higher mean pulmonary artery pressure as factors suggesting an IPAH diagnosis. Non-operable CTEPH is more similar to IPAH than operable CTEPH regarding risk factors.

scholarly journals Analysis of the Influence of Risk Factors of Type 2 DM on Outpatients at DKT Bandar Hospital Lampung, 2020

2021 ◽  
Vol 4 (2) ◽  
pp. 4-14
Author(s):  
Feby Esmiralda ◽  
Aila Karyus ◽  
Kodrat Pramudho
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Univariate Analysis ◽  
Bivariate Analysis ◽  
P Value ◽  
History Of

DM is a chronic metabolic disease characterized by hyperglycemia and cause serious complications with an increasing prevalence rate. Control of risk factors that affect the incidence of DM is needed to prevent the emergence of DM and delay disease complications. The purpose of this study is to determine the risk factors that influence the incidence of type 2 diabetes outpatients at the DKT Bandar Lampung Hospital. This type of research is quantitative observational analytic with a case control approach. The population came from all patients undergoing outpatient treatment at the Internal Medicine Department of the DKT Hospital in Bandar Lampung with 44 case samples and 44 control samples. Data analysis used univariate analysis with percentages, bivariate analysis with Chi Square and multivariate analysis with multiple logistic regression. The results showed that there was a significant influence between the risk factors for age (p value 0.017), hereditary history of diabetes (p value 0.03), physical activity (p value 0.002) and obesity (p value 0.001) with the incidence of type 2 diabetes, while a history of hypertension has no effect on the incidence of type 2 diabetes mellitus (p value 0.135). Meanwhile, the most dominant variable influencing the incidence of outpatient type 2 diabetes mellitus at DKT Bandar Lampung Hospital is physical activity with OR 5.29. Maximum promotive, preventive, curative and rehabilitative efforts are needed to control risk factors for type 2 diabetes

scholarly journals RISK FACTORS OF CARDIOVASCULAR DISEASE AMONG ST-ELEVATION MYOCARDIAL INFARCTION MALE PATIENTS IN MALAYSIA FROM 2006 TO 2013

2019 ◽  
Vol 81 (3) ◽  
Author(s):  
Nurliyana Juhan ◽  
Zarina Mohd Khalid ◽  
Yong Zulina Zubairi ◽  
Ahmad Syadi Mahmood Zuhdi ◽  
Wan Azman Wan Ahmad
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Myocardial Infarction ◽  
Cardiovascular Disease ◽  
Risk Factor ◽  
Univariate Analysis ◽  
St Elevation Myocardial Infarction ◽  
Coronary Syndrome ◽  
St Elevation ◽  
Male Patients

Cardiovascular disease is the leading cause of death in Malaysia and globally. This study aimed to identify associated risk factors in cardiovascular disease among ST elevation myocardial infarction (STEMI) male patients and obtain a feasible model to describe the data. A total of 16,673 STEMI male patients from 18 participating hospitals across Malaysia in the National Cardiovascular Disease Database-Acute Coronary Syndrome (NCVD-ACS) registry year 2006-2013 were analysed. Univariate analysis was conducted. Significant variables from the univariate analysis were further analysed by a multivariate logistic analysis to identify the prognostic factors. The most prevalent risk factor for male patients was smoking (79.3%), followed by hypertension (54.9%) and diabetes mellitus (40.4%). At univariate level, this study is consistent with the findings from the Malaysian National Health and Morbidity Survey (NHMS) where smoking is a significant risk factor. After adjustment in multivariate logistic model, the risk factors for cardiovascular death among male patients are related to age, premorbid condition such as diabetes mellitus, hypertension, family history of CVD, Killip class, type of treatment such as percutaneous coronary intervention (PCI) and relevant comorbidity such as renal disease. Drastic efforts in the management of all risk factors in males is needed to improve adherence outcomes.

scholarly journals ACUTE MYOCARDIAL INFARCTION

2016 ◽  
Vol 23 (03) ◽  
pp. 293-297
Author(s):  
Rafaqat Malik ◽  
Shazma Begum ◽  
Muhammad Nazar Afridi
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Risk Factor ◽  
Modifiable Risk Factors ◽  
Common Risk Factor ◽  
Cardiology Department ◽  
The World ◽  
History Of

The frequency of modifiable risk factors of acute myocardial infarction variesgreatly in different countries and populations of the world. Objective: To find out the frequencyof modifiable risk factors in patients with acute myocardial infarction. Design: Cross-sectionalstudy. Setting: Cardiology Department. Ayub Teaching Hospital Abbottabad, Period: 1st Jan2015 and 30th June 2015. Material and Methods: A total of 224 patients of acute myocardialinfarction Patients were enquired about the presence of hypertension, diabetes mellitus,smoking and family history of ischemic heart disease. Fasting blood sugar and lipid profilewere recorded. Results: Out of 224, 90.6% patients had at least one risk factor. Hypertensionwas found to be the most common risk factor (55.4%), followed by smoking (43.8%) andDiabetes Mellitus (27.2%). Dyslipidemia was found to be the least common (23.2%) risk factor.Conclusion: Hypertension is the most common modifiable risk factor in patients of acutemyocardial infarction, followed by smoking and diabetes.

scholarly journals Results of carotid endarterectomy in diabetic patients

Medicina ◽  
2007 ◽  
Vol 43 (9) ◽  
pp. 685
Author(s):  
Auksė Meškauskienė ◽  
Egidijus Barkauskas ◽  
Virginija Gaigalaitė
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Myocardial Infarction ◽  
Carotid Endarterectomy ◽  
Carotid Stenosis ◽  
Diabetic Patients ◽  
Bilateral Carotid ◽  
Patients With Diabetes ◽  
Intracerebral Hemorrhages ◽  
Vilnius University

Patients with diabetes mellitus have been shown to have an increased incidence of complications after major vascular surgery. The objective of this study was to evaluate the results of carotid endarterectomy in diabetic patients, to determine if results differ from nondiabetic patients, and to examine the risk factors for poor outcome among diabetic patients. Material and methods. We reviewed all carotid endarterectomies performed in Emergency Hospital of Vilnius University. From 1995 to 2005, 707 carotid endarterectomies were performed. Of these, 100 operations were performed in diabetic patients (14%) and the remaining 607 in nondiabetic patients. Results. Diabetic patients were younger (P<0.05) and were obese more often (P<0.001), they smoked less often (P<0.001) than nondiabetic patients. Diabetics were more likely to have severe bilateral carotid stenosis than nondiabetic patients (P<0.01). Postoperative complications (stroke) were more common in diabetic patients than in nondiabetic patients (12.0% vs. 3.4%, P<0.001) as well as intracerebral hemorrhages (3.0% vs. 0.3%, P<0.001); no perioperative myocardial infarction was found in diabetic patients. Risk factors for complications were age ≥75 (odds ratio (OR) 2.2; 95% confidence interval (CI)=1.0–4.9), smoking (OR 2.7; 95% CI=1.8– 4.2), obesity (OR 6.1; 95% CI=3.9–9.5), and bilateral carotid stenosis (OR 2.1; 95% CI=1.3–3.6). Conclusion. Diabetes mellitus significantly increased the risk of mortality and intracerebral hemorrhage but not myocardial infarction. It should be taken into consideration in making decisions about the performance and perioperative management of carotid endarterectomy.

scholarly journals Moterų insulto rizikos veiksniai ir jų įtaka miego arterijos endarterektomijos rezultatams

2005 ◽  
Vol 3 (2) ◽  
pp. 0-0
Author(s):  
Auksė Meškauskienė ◽  
Egidijus Barkauskas ◽  
Virginija Gaigalaitė ◽  
Kęstutis Laurikėnas
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Sex Differences ◽  
Carotid Endarterectomy ◽  
Stroke Risk ◽  
Study Cohort ◽  
Complication Rates ◽  
Surgical Risk ◽  
Stroke Risk Factors ◽  
History Of

Auksė Meškauskienė, Egidijus Barkauskas, Virginija Gaigalaitė, Kęstutis LaurikėnasVilniaus universiteto Neurologijos ir neurochirurgijos klinikosNeuroangiochirurgijos centras,Šiltnamių g. 29, LT-04130 VilniusEl paštas: [email protected] Įvadas / tikslas Literatūroje pateikiama prieštaringų duomenų apie miego arterijos endarterektomijos operacinę riziką moterims, palyginti su vyrais. Mes išanalizavome moterų ir vyrų tradicinius insulto rizikos veiksnius ir jų prognozinę reikšmę miego arterijos endarterektomijos rezultatams. Ligoniai ir metodai Išanalizavome Vilniaus greitosios pagalbos universitetinėje ligoninėje 1995–2003 m. operuotų nuo miego arterijos stenozės ligonių duomenis ir palyginome insulto rizikos veiksnius, gretutines ligas bei operacinę mirties, insulto ir miokardo infarkto riziką priklausomai nuo lyties. Naudojomės logistinės regresijos metodu, kad nustatytume moterų ir vyrų chirurginę riziką pagal amžių ir kitus insulto rizikos veiksnius. Rezultatai Ištyrėme 129 moterų ir 373 vyrų duomenis. Moterys, palyginti su vyrais, buvo vyresnio amžiaus, dažniau sirgo arterine hipertenzija, daugiau buvo nutukusių ir turėjo padidėjusį cholesterolio kiekį, bet mažiau rūkė. Arterinė hipertenzija ir hipercholesterolemija buvo dažniausiai pasitaikantys moterų insulto rizikos veiksniai. Moterų sergamumas vainikine širdies liga, periferinių arterijų obliteruojančia ateroskleroze, cukriniu diabetu statistiškai reikšmingai nesiskyrė nuo vyrų. Moterų operacinių komplikacijų buvo mažiau nei vyrų, tačiau skirtumas nebuvo statistiškai reikšmingas (mirčių – 2,3% vs 3,5%; operacinių insultų – 0,8% vs 2,1%; miokardo infarktų – 1,5% vs 1,9%, visais atvejais p > 0,05), o tradiciniai insulto rizikos veiksniai turėjo mažai įtakos komplikacijoms pasireikšti. Didžiausia operacinių komplikacijų tikimybė nustatyta moterims, sergančioms cukriniu diabetu (ŠS 7,43; 95% PI 1,7–17,8, p < 0,002). Išvados Moterų miego arterijos endarterektomijos komplikacijų skaičius nebuvo didesnis nei vyrų ir neviršijo 6 procentų nustatytos ribos, kai išnyksta operacinio gydymo pranašumas medikamentinio atžvilgiu. Cukrinis diabetas yra potencialus moterų galimų operacinių komplikacijų rizikos veiksnys. Reikšminiai žodžiai: insulto rizikos veiksniai, miego arterijos endarterektomija, moterys, komplikacijų rizika Stroke risk factors and their impact on the surgical risk of carotid endarterectomy in women Auksė Meškauskienė, Egidijus Barkauskas, Virginija Gaigalaitė, Kęstutis LaurikėnasVilnius University, Clinic of Neurology and Neurosurgery,Center of Neurovascular Surgery,Šiltnamių str. 29, LT-04130 Vilnius, LithuaniaE-mail: [email protected] Background / objective The literature provides conflicting evidence regarding surgical risks of carotid endarterectomy in women as compared to men. We used data from our carotid surgery registry to determine whether sex differences exist in the stroke risk factors and their impact on the surgical risk of carotid endarterectomy. Patients and methods We have analyzed data on all patients operated on for carotid artery stenosis at the Vilnius Emergency Hospital in 1995–2003 and have compared gender-dependent stroke risk factors, concomitant diseases and the perioperative risks of death, sroke and myocardical infarction. The logistic regression method was employed to determine the surgical risk in men and women depending on age and other risks of stroke. Results The study cohort consisted of 129 women and 373 men. Women were older than men, more likely to have a history of hypertension; they were more obese, had higher levels of cholesterol and less of them smoked. There were no significant sex differences in the history of coronary artery disease, diabetes mellitus and peripheral vascular disease. The incidence of death, stroke and myocardial infarction in women was even slightly lower than in men (2.3% versus 3.5%; 0.8% versus 2.1%; 1.5% versus 1,9%, all p > 0,05). Diabetes mellitus (OR odds ratio 7.43; 95% CI 1.7 to 17.8, p < 0.002) was predictive of a higher surgical risk in women. Conclusions Operative complication rates from carotid endarterectomy in women were not worse than in men and did not exceed the recommended upper limits for operative risk, confirming the beneficial effects of carotid endarterectomy in women. Diabetes mellitus was a potential prognostic factor for a higher surgical risk in women. Keywords: stroke risk factors, carotid endarterectomy, women, surgical risk

scholarly journals Description of ST Segments Elevation of Myocardial Infarction on Patients Undergoing Primary Percutaneous Coronary Intervention in dr. M. Djamil Hospital Padang

2020 ◽  
Vol 7 (1) ◽  
pp. 1
Author(s):  
Pradita Diah Permatasari ◽  
Muhammad Fadil ◽  
Masrul Syafri
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Myocardial Infarction ◽  
Percutaneous Coronary Intervention ◽  
Family History ◽  
Primary Percutaneous Coronary Intervention ◽  
Univariate Analysis ◽  
Coronary Intervention ◽  
Percutaneous Coronary ◽  
St Segments

Myocardial infarction is influenced by various risk factors consist of gender, age, family history, smoking, hypertension, dyslipidemia, diabetes mellitus and menopause. The aim of this study was to describe the description of sex, age and risk factors possessed by patients with ST segments Elevation Myocardial Infarction (STEMI) who underwent primary percutaneous coronary intervention (PPCI) procedures at Dr. M. Djamil hospital Padang. Amount of 40 people were obtained specifically for STEMI patients who underwent PPCI and were treated at the integrated heart services installation of RSUP dr. M. Djamil Padang from July-September 2019. The research variables measured were age, sex, risk factors for hypertension, diabetes mellitus, smokers, dyslipidemia, family history and menopause. Data was analyzed in the form of univariate analysis, which explained each research variable according to the proportion and frequency values. The results were found in 40 patients with acute ST segments elevation myocardial infarction, all aged > 40 years, most were male (85%) and the most risk factor was smoking (82,5%). We conclude that STEMI patients who underwent PPCI in dr.M. Djamil hospital Padang from July-September 2019 were all > 40 years old, most were male, with the most risk factors were smokers.

scholarly journals Risk factors for elevated serum colorectal cancer markers in patients with type 2 diabetes mellitus

2020 ◽  
Vol 15 (1) ◽  
pp. 267-273
Author(s):  
Jingjing Guo ◽  
Bin Wang ◽  
Weikai Hou ◽  
Kun Ma
Keyword(s):  
Diabetes Mellitus ◽  
Colorectal Cancer ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Tumor Marker ◽  
Univariate Analysis ◽  
Serum Carcinoembryonic Antigen ◽  
History Of

AbstractThe study aims to examine the risk factors for increased colorectal cancer (CRC) markers in patients with type 2 diabetes mellitus (T2DM). The 229 patients retrospectively reviewed were categorized into two groups: CRC tumor marker-positive and -negative groups. Patients who tested positive for all three of the following CRC markers were included in the CRC tumor marker-positive group: serum carcinoembryonic antigen, carbohydrate antigen 19-9 and septin9 methylation. Univariate analysis revealed that most CRC marker-positive patients had higher age, a family history of CRC, history of smoking and alcohol intake, high body mass index (BMI; overweight), longer history of T2DM, worse diabetes control (with high glycated hemoglobin A1c [HbA1c]), lower level of serum vitamin D (VD), high-density lipoprotein cholesterol and higher level of total cholesterol and triglyceride (TG). Logistic regression analysis showed that BMI, VD, HbA1c and TG were independent predictors of CRC marker-positive status (OR, 95% confidence intervals and P values were 1.912 [1.346–2.716], <0.001; 0.773 [0.633–0.943], 0.011; 9.082 [3.52–23.433], <0.001; and 11.597 [3.267–41.164], <0.001, respectively). In this retrospective study, high BMI, HbA1c and TG as well as low level of VD were correlated with CRC tumor marker-positive status in T2DM patients. Patients with these risk factors may benefit from more frequent screening for CRC tumor markers.

CARDIOVASCULAR RISK FACTORS PECULIARITIES IN MEN UNDER 60 YEARS OLD WITH MYOCARDIAL INFARCTION AND CHRONIC INFLAMMATORY LUNG DISEASES

2020 ◽  
pp. 21-25
Author(s):  
Tupitsyn V.V. ◽  
Bataev Kh.M. ◽  
Men’shikova A.N. ◽  
Godina Z.N.
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Digestive System ◽  
Control Group ◽  
Study Group ◽  
Type I ◽  
Internal Organs ◽  
History Of

Relevance. Information about the cardiovascular diseases risk factors (CVD RF) for in men with chronic lung inflam-matory pathology (CLID) is contradictory and requires clarification. Aim. To evaluate the peculiarities of CVD RF in men under 60 years of age with CLID in myocardial infarction (MI) to improve prevention. Material and methods. The study included men aged 19-60 years old with type I myocardial infarction. Patients are divided into two age-comparable groups: I - the study group, with CLID - 142 patients; II - control, without it - 424 patients. A comparative analysis of the frequency of observation of the main and additional cardiovascular risk fac-tors in groups was performed. Results. In patients of the study group, more often than in the control group we observed: hereditary burden of is-chemic heart disease (40.8 and 31.6%, respectively; p = 0.0461) and arterial hypertension (54.2 and 44.6%; p = 0.0461), frequent colds (24.6 and 12.0%; p = 0.0003), a history of extrasystoles (19.7 and 12.7%; p = 0.04); chronic foci of infections of internal organs (75.4 and 29.5%; p˂0.0001), non-ulcer lesions of the digestive system (26.1 and 14.6%; p = 0.007), smoking (95.1 and 66.3%; p˂0.0001), MI in winter (40.8 and 25.9%; p = 0.006). Less commonly were observed: oral cavity infections (9.2 and 23.6%; p˂0.0001); hypodynamia (74.5 and 82.5%; p = 0.0358), over-weight (44.4 and 55.2%; p = 0.0136), a subjective relationship between the worsening of the course of coronary heart disease and the season of the year (43.7 and 55.2%; p = 0.0173) and MI - in the autumn (14.1 and 21.9%; p = 0.006) period. Conclusions. The structure of CVD RF in men under 60 years of age with CLID with MI is characterized by the pre-dominance of smoking, non-ulcer pathology of the digestive system, frequent pro-student diseases, meteorological dependence, a history of cardiac arrhythmias and foci of internal organ infections. It is advisable to use the listed factors when planning preventive measures in such patients.

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