Abstract WMP118: In Safe Hands: Implementation on the Stroke Unit. Does it Improve Patient Care and Ward Efficiency?

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Sheila M Jala ◽  
Sarah Giaccari ◽  
Melissa Passer ◽  
Carin Bertmar ◽  
Susan Day ◽  
...  
Keyword(s):  
Length Of Stay ◽  
Stroke Unit ◽  
Oral Intake ◽  
Improve Patient Care ◽  
Tertiary Hospital ◽  
Study Data ◽  
Acute Hospital ◽  
Staff Satisfaction ◽  
Number Of Patients ◽  
Significant Difference

The ‘In Safe Hands” (ISH) is a structured interdisciplinary bedside round developed to increase patients participation in their care in acute hospital wards. This has shown to improve quality of care by reducing communication errors and complications, enhancing a culture of safety in an acute hospital. The purpose of this study was to assess the effect of ISH on length of stay (LOS), in-hospital complications and assess whether the ISH enhances patient and staff satisfaction in a stroke unit of a tertiary hospital in Sydney, Australia. This was a longitudinal study pre and post implementation. A total of 200 patients participated in the study. Data on the length of stay, incidence rate relating to patient safety and patient and staff satisfaction surveys using Patient Experience Tracker (PET) devices were collected pre and post implementation. ISH increased the number of patients with at least 72hours in stroke unit care by 80 percent (P < 0.001). Fever and hyperglycaemia were treated in all patients following ISH implementation vs only 50% and 64% respectively of patients pre ISH implementation. Swallow screen was completed in all patients prior oral intake compared to 92% of patients of the pre ISH group (P = 0.03). There was no significant difference in the LOS and complications. All stroke patients received stroke education and there were no readmissions post implementation. There was no significant difference in the patient and staff satisfaction. In conclusion, although ISH did not improve the primary endpoints of LOS, complications and satisfaction it did improve protocol adherence.

scholarly journals Fournier’s Gangrene: 10-Year Experience of a Plastic Surgery and Burns Department at a Tertiary Hospital

2019 ◽  
Vol 32 (5) ◽  
pp. 368 ◽  
Author(s):  
João Mendes Louro ◽  
Miguel Albano ◽  
João Baltazar ◽  
Miguel Vaz ◽  
Carla Diogo ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Escherichia Coli ◽  
Length Of Stay ◽  
Plastic Surgery ◽  
Tertiary Hospital ◽  
Fournier’S Gangrene ◽  
Fournier's Gangrene ◽  
Fournier Gangrene ◽  
Number Of Patients ◽  
Reconstructive Techniques

Introduction: Fournier gangrene is a polymicrobial life threatening infection of perineal subcutaneous soft tissues with its point of origin in urologic, colorectal or skin diseases. Although more frequent in elderly and men, it can affect all genders and age groups. Perianal abscess, diabetes mellitus and Escherichia coli are the most frequent cause, predisposing comorbidity, and microorganism found in tissue culture analysis respectively. The objective of this study was to describe the experience of a Plastic Surgery Department of a tertiary Hospital in reconstructing Fournier’s gangrene perineal defects and its detailed demography.Material and Methods: The sample is composed of all patients with Fournier gangrene admitted in the Plastic Surgery and Burns Department. The authors retrospectively collected and analyzed demographic and clinical data during a period of 10 years including gender, age, length of stay, cause, number of debridements, predisposing factors, microbial culture results, surgical reconstructive techniques and its associated complications, additional surgical procedures and outcomes.Results: Fifteen patients were identified: 14 males (93%) and one female (7%); mean age was 66.9 years (range: 46 - 86); mean, length of stay was 46.8 days (range: 20 - 71 days) and mean number of debridements was 3.3 (range: 1 - 4). The most frequent predisposing factor was diabetes mellitus, the major cause was perianal (n = 2) and skin abscess (n = 2). Eight (53.3%) patients had no identifiable source of Fournier gangrene. Various types of reconstructive techniques were employed; and 5 additional surgical interventions (33.3%) were undertaken (one cystostomy, two orchidectomy, two ileostomy); six patients (40%) presented reconstructive technique complications with adequate final outcome.Discussion: In contrast with the literature, where Escherichia coli was the most frequently isolated agent, Staphylococcus aureus was the most frequent microorganism found in tissue biopsy/pus collection analysis. A higher than expected number of patients (n = 8) had no identifiable source of Fournier gangrene. This findings can be explained by the retrospective non-multicentre study limitation, with a potencial source of bias patients that were transferred from other hospitals in advanced stage, without point of origin of Fournier’s gangrene identified.Conclusion: Early recognition and extensive necrotic tissue debridement, along with prompt and adequate antimicrobial treatment, are the mainstay of Fournier gangrene management, thus reducing morbidity and mortality in these patients. Surgical reconstruction challenges derived from this condition should be addressed by specialized teams due to the risk of dysfunctional sequelae and conspicuous deformities. Taking in account the single-center and retrospective observational character of the present study, these premises require proper validation from a multicenter prospective study.

Oncology consults in admitted cancer patients: The ways to reduce length of stay.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e13516-e13516
Author(s):  
Bohdan Baralo ◽  
Muhammad Hanif ◽  
Archen Krupadev ◽  
Sabah Iqbal ◽  
Navyamani Kagita ◽  
...  
Keyword(s):  
Length Of Stay ◽  
Cancer Patients ◽  
Hospice Care ◽  
Medical Center ◽  
Severe Disease ◽  
Tertiary Care ◽  
Charlson Score ◽  
Primary Malignancy ◽  
Number Of Patients ◽  
Significant Difference

e13516 Background: The cancer patients, while being admitted to the hospital often have an oncologist consult (OC) through the admission. The goal of the study is to assess, whether OC impact the length of stay (LOS) and to define the group of cancer patients in whom omitting the OC can decrease LOS. Methods: We reviewed 415 admissions of cancer patients from 1/1/2018 to 11/30/2020 to the both campuses of Mercy Catholic Medical Center. We included patients who are 18 years or older with confirmed malignancy. We excluded COVID positive, patients who died during admission, were transferred to tertiary care institutions, or were recommended hospice care, but decided to continue treatment despite poor prognosis. Patient with hematologic disorders were excluded as well. The LOS of stay in cancer patients with and without OC will be compared using two tailed unpaired t-test and Mann-Whitney test ( < 20 admissions in each group, or one of the groups had a largely skewed data). Sub-analysis will be done accounting for Charlson score, spread of the disease and reason of admission (cancer vs non-cancer related). Statistical software Prism 9 will be used for analysis. Results: 290 admissions were selected using inclusion and exclusion criteria. Throughout all admission 234 admission had OC and mean LOS was 4.86 day compare to 4.23 in 56 patients, who did not have OC. Patients with non-cancer related (non-CR) admissions who had Charlson score ≤6 and no OC had shorter LOS (13 admission with median LOS 3 days) compared to those who had OC (11 admissions with LOS 7days), p 0.0462. Also, patient with non-CR admission and localized cancer tend have shorter LOS when no OC involved (15 admission with median LOS 6 days) compare to OC (16 admissions with median LOS 2.5 days), p 0.0365. No other significant difference in LOS were observed (Table). Conclusions: The cancer patients admitted for the reasons not related to their primary malignancy and who have either localized disease or Charlson score < 6 have shorter length of stay when OC not done. The limitation of the current study is the small number of patients in analysis subgroups, as well as fact that patients who had OC may have more severe disease during admission, despite the fact that patient had same extend of disease and comorbidities. Study with larger number of admissions may be necessary to confirm findings of this study.[Table: see text]

Helmet use and reduction in skull fractures in skiers and snowboarders admitted to the hospital

2011 ◽  
Vol 7 (3) ◽  
pp. 268-271 ◽  
Author(s):  
Anand I. Rughani ◽  
Chih-Ta Lin ◽  
Wiliam J. Ares ◽  
Deborah A. Cushing ◽  
Michael A. Horgan ◽  
...  
Keyword(s):  
Head Injury ◽  
Length Of Stay ◽  
Skull Fracture ◽  
Ct Scans ◽  
Spine Injury ◽  
Intracranial Injury ◽  
Helmet Use ◽  
Number Of Patients ◽  
Significant Difference ◽  
Secondary Outcomes

Object Helmet use has been associated with fewer hospital visits among injured skiers and snowboarders, but there remains no evidence that helmets alter the intracranial injury patterns. The authors hypothesized that helmet use among skiers and snowboarders reduces the incidence of head injury as defined by findings on head CT scans. Methods The authors performed a retrospective review of head-injured skiers and snowboarders at 2 Level I trauma centers in New England over a 6-year period. The primary outcome of interest was intracranial injury evident on CT scans. Secondary outcomes included the following: need for a neurosurgical procedure, presence of spine injury, need for ICU admission, length of stay, discharge location, and death. Results Of the 57 children identified who sustained a head injury while skiing or snowboarding, 33.3% were wearing a helmet at the time of injury. Of the helmeted patients, 5.3% sustained a calvarial fracture compared with 36.8% of the unhelmeted patients (p = 0.009). Although there was a favorable trend, there was no significant difference in the incidence of epidural hematoma, subdural hematoma, intraparenchymal hemorrhage, subarachnoid hemorrhage, or contusion in helmeted and unhelmeted patients. With regard to secondary outcomes, there were no significant differences between the 2 groups in percentage of patients requiring neurosurgical intervention, percentage requiring admission to an ICU, total length of stay, or percentage discharged home. There was no difference in the incidence of cervical spine injury. There was 1 death in an unhelmeted patient, and there were no deaths among helmeted patients. Conclusions Among hospitalized children who sustained a head injury while skiing or snowboarding, a significantly lower number of patients suffered a skull fracture if they were wearing helmets at the time of the injury.

scholarly journals Study comparing the stroke unit outcome and conventional ward treatment: a randomized study in Joinville, Brazil

2003 ◽  
Vol 61 (2A) ◽  
pp. 188-193 ◽  
Author(s):  
Norberto L. Cabral ◽  
Carla Moro ◽  
Giana R. Silva ◽  
Rosana Herminia Scola ◽  
Lineu César Werneck
Keyword(s):  
Hospital Stay ◽  
Stroke Unit ◽  
Survival Curve ◽  
Clinical Status ◽  
Randomized Study ◽  
Length Of Hospital Stay ◽  
General Ward ◽  
Number Of Patients ◽  
Significant Difference ◽  
The Impact

BACKGROUND AND PURPOSE: To assess the impact of a stroke unit (SU) on acute phase treatment when compared to a conventional general ward treatment (GW). METHOD: Seventy-four patients with acute stroke were randomized between a SU and conventional general ward (GW). We compared both groups regarding the length of hospital stay, lethality and functional and clinical status within 6 months, using the Scandinavian scale and Barthel index. RESULTS: Thirty-five and thirty-nine patients were allocated at SU and GW, respectively. Lethality on the 10th day at SU and GW achieved 8.5% and 12.8% respectively (p= 0.41), whereas 30-days mortality rates achieved 14.2% and 28.2% (p= 0.24), 17.4% and 28.7% on the 3rd month (p= 0.39), and 25.7% and 30.7% on the 6th month (p= 0.41). Thirty-day survival curve achieved 1.8 log rank (p= 0.17), with a trend for lower lethality in the SU. In order to save one death in 6 months in SU, NNT (the number need to treat) was 20; to get one more home independent patient NNT was 15. No significant difference was found between the length of hospital stay and morbidity. CONCLUSION: No significant benefit was found in SU patients compared to GW group. However,an evident benefit in absolute numbers was observed in lethality, survival curve and NNT in thirty days period after stroke. Further collaborative studies or incresead number of patients are required to define the role of SU.

Abstract TP404: Optimizing Length of Stay Through an Integrated Communication Strategy

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Kimberly Smith ◽  
Arianne Navarro ◽  
Shanequa Sostand ◽  
Nicole Harrison ◽  
Sean Savitz
Keyword(s):  
Length Of Stay ◽  
Text Messaging ◽  
Stroke Unit ◽  
Text Message ◽  
Communication Strategy ◽  
Notification System ◽  
Number Of Patients ◽  
Unit Capacity ◽  
Integrated Communication ◽  
Control Feedback

Background: At our comprehensive stroke center, the Stroke Unit bed ahead tool allows bed availability to be reported every four hours and identifies patients who may be available for discharge or transfer out of the unit. A Stroke Bed Ahead Algorithm is utilized and information is communicated using a paper format and an online text messaging system called EZ Texting. Purpose: The purpose of this study is to improve bed flow through coordination and facilitation of movement in the Stroke Unit and to provide quality control feedback of the efficiency of bed flow within the Stroke Unit. A bed ahead tool is utilized to decrease divert activity of the hospital and decrease length of stay on the Stroke Unit, thereby decreasing length of stay in the hospital. Intervention: The Stroke Unit charge and staff nurses evaluate patients appropriate for possible discharge or transfer out of the Stroke Unit. A Stroke Unit capacity text message is then sent out by the Charge Nurse or the Unit Coordinator every four hours starting at 0800. The capacity text message includes the total number of patients and patients pending to be received or transferred out of the unit. Results: Utilizing an integrated communication strategy decreased the length of stay of stroke population by 12%. Implications of Practice: Implementation of Stroke Unit capacity notification system decreases the length of stay and decreases divert activity of the hospital.

Opioid Sparing in Cleft Palate Surgery

2018 ◽  
Vol 55 (9) ◽  
pp. 1200-1204 ◽  
Author(s):  
Logan Carr ◽  
Megan Gray ◽  
Brad Morrow ◽  
Morgan Brgoch ◽  
Donald Mackay ◽  
...  
Keyword(s):  
Length Of Stay ◽  
Cleft Palate ◽  
Medical Center ◽  
Demographic Data ◽  
Oral Intake ◽  
Treatment Groups ◽  
Pain Scores ◽  
Opioid Sparing ◽  
Significant Difference ◽  
Sparing Effect

Objective: This study aimed to determine whether intraoperative acetaminophen was able to decrease opioid consumption, pain scores, and length of stay while increasing oral intake in cleft palate surgery. Design/Setting/Patients: One hundred consecutive patients with cleft palate who underwent a von Langenbeck or 2-flap palatoplasty and intravelar veloplasty at a tertiary medical center by the 2 senior authors from 2010 to 2015 were reviewed. Interventions: Three intraoperative treatment groups were analyzed: intravenous (IV) acetaminophen, per rectal (PR) acetaminophen, and no acetaminophen. All patients received long-acting local anesthesia infiltration before incision. Additionally, all patients were admitted overnight and given weight-based per oral (PO) acetaminophen and oxycodone and IV morphine as needed based on pain scores. Outcomes Measured: The study outcomes included pain scores, opioid requirement, length of stay, and oral intake. Results: The treatment groups were comprised of 40 patients who received IV acetaminophen, 22 PR acetaminophen, and 35 none. Concerning demographic data, there was no statistical difference between treatment groups. There was no statistically significant difference for opioid intake, although both IV and PR acetaminophen groups had decreased pain scores ( P = .029). There was no difference in oral intake ( P = .13) or length of stay ( P = .31) between treatment groups. Conclusion: In this study, intraoperative administration of acetaminophen was associated with decreased pain scores, but no opioid-sparing effect. As other studies have shown an opioid-sparing effect with postoperative acetaminophen, we recommend withholding the intraoperative dose and beginning therapy in the immediate postoperative period.

Effect of tele-stroke application on length of stay and outcome of stroke unit inpatients

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Naglaa Mohamed El-khayat ◽  
Tamer Hussein Emara ◽  
Tamer Mahmoud Roushdy ◽  
khaled Fayez Elmancy
Keyword(s):  
Length Of Stay ◽  
Acute Stroke ◽  
Stroke Unit ◽  
Healthcare Delivery ◽  
P Value ◽  
Group I ◽  
Wide Range ◽  
Significant Difference ◽  
Before And After ◽  
Group Ii

Abstract Background Despite advances in acute stroke treatment, stroke remains the second most common cause of death and the leading cause for long-term adult disability worldwide Telemedicine, a method of healthcare delivery and support using telecommunication technologies, is becoming increasingly popular across a wide range of health conditions. Tele stroke has grown significantly in the past decade and has entered mainstream care for patients with acute stroke. It enables such patients to be remotely evaluated, thereby allowing optimal treatment and management even in clinically underserved areas and removing geographical disparities in access to expert care. Objective Study the effectiveness of Tele-stroke regarding length of stay& stroke outcomes &occurrence of medical comorbidities in admitted patients by comparing these measures before and after tele stroke application in ain shams university specialized hospital(ASUSH) Methods Comparative observational study. we stratified patients into two groups: “Group 1”: patients admitted 3 months before application of tele stroke “Group 2”: patients admitted 3 months after application of tele stroke We compared between two groups regarding sociodemographic data , length of stay and NIH scoring on admission & discharge before and after implementation of tele stroke system Results regarding length of stay, it was ranged from 1 to 19 days with mean (4.3 ± 3.3) in group (I) comparing to range 1 to 12 with mean (3.5 ± 1.9) days in group (II) with significant decrease (p = 0.033*). By analysis of results by means for difference between NIH on admission and in discharge , the means difference in group I was 2.8±1.9 vs. 3.5±2.3 in group II with significant difference (p-value =0.29*) CONCLUSION Our study concluded that application of tele stroke had significant improvement in stroke unit care as regard length of stay, rapid improvement of patients according to NIH scoring and mRS

scholarly journals The effectiveness of an emergency physician–led frailty unit for the living-alone elderly: A pilot retrospective cohort study

2019 ◽  
Vol 27 (3) ◽  
pp. 162-167
Author(s):  
Tsz-Hang Leung ◽  
Sai-Choi Leung ◽  
Chi-Keung Gordon Wong
Keyword(s):  
Cohort Study ◽  
Length Of Stay ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Care Pathway ◽  
Acute Hospital ◽  
Living Alone ◽  
Ageing Population ◽  
Attendance Rate ◽  
Significant Difference

Background: We are facing an ageing population in Hong Kong. In response to the surge in service demand resulted from Silver Tsunami, a six-bed frailty unit was established in the Emergency Medicine Ward of Queen Elizabeth Hospital in December 2015. Frailty unit offers a bundle of multi-disciplinary approach for geriatric patients with an aim for early supported discharge. Objective: To evaluate whether this novel frailty care pathway, compared to the conventional general care pathway, would improve the outcome of the local elderly who were living alone. Method: This is a retrospective cohort study. Patients who were admitted from 1 September 2015 to 31 October 2017 were included in this study. Data were retrieved from the electronic patient record (ePR) of Hospital Authority. The outcome measurements are lengths of stay in acute and convalescent hospitals, transferral rate to a convalescent hospital and 28-day re-attendance rate. Results: A total of 190 patients were recruited (150 frailty vs 40 general). Baseline characteristics, including age, gender distribution, vital signs, laboratory results, use of mobility aids, Morse fall risk scale, Norton ulcer scale and Barthel Index were similar in both groups; except a higher diastolic blood pressure in novel frailty-care pathway. The length of stay in the acute hospital is significantly shortened (2.38 vs 3.27 days, p = 0.00018). The transferral rate to a convalescent hospital was less in frailty group (21.3% vs 42.5%, p = 0.00655). There was no significant difference in terms of total (7.10 vs 10.99 days, p = 0.09638) and convalescent (22.09 vs 18.16 days, p = 0.48183) length of stay between frailty group and general group, respectively; while the 28-day re-attendance rate was similar (26.7% vs 15.0%, p = 0.12589). Conclusion: This is a pilot study to first report a novel frailty-care model for the local geriatric population. It has shown a reduction in length of stay in acute hospital and transferral rate to convalescent hospitals, while introducing a non-significant reduction in total hospital stay, maintaining 28-day re-attendance rate and at an expense of a probable increase in the convalescent stay.

scholarly journals A COMPARATIVE EVALUATION OF PRESCRIBING PRACTICE OF ANTIBIOTIC PROPHYLAXIS IN HOSPITALS OF POKHARA VALLEY

1970 ◽  
Vol 43 (156) ◽  
Author(s):  
Nami Palikhe ◽  
A Pokhrel
Keyword(s):  
Length Of Stay ◽  
Antibiotic Prophylaxis ◽  
Length Of Hospital Stay ◽  
Study Data ◽  
Significant Difference ◽  
Prescribing Practice ◽  
The Common ◽  
The Mean ◽  
Western Regional ◽  
Pokhara Valley

The main objective of the study was to assess the prescribing practice of antibiotic prophylaxis for differentsurgeries in hospitals of Pokhara valley. A descriptive, quantitative, retrospective study was used to evaluatethe patients who have undergone surgery between 15th April 2002 – 14th April 2003. A total of 950 patientswere taken from the medical record for the study. Data about patient (age, sex), surgery (type and indication),antibiotic/s prophylaxis (dose, duration) and length of hospital stay were collected. Caesarean Section (CS)was the common surgery in Western Regional Hospital (WRH) followed by cholecystectomy, 31.1% and24.4% respectively. In Manipal Teaching Hospital (MTH), dilatation and currettage (D and C, 21.6%) wasthe most common surgery followed by hysterectomy (21%). The mean length of stay in MTH for CS surgerywas 7.97 days whereas 7.01 days for WRH. Significant difference was found in length of stay of two hospitals(p<0.05). Antibiotic prophylaxis was given preoperatively in MTH (87%) and WRH (79.5%) respectively.Antibiotic prophylaxis was given intraoperatively in 1.2% cases of MTH. In MTH, the total antibioticduration in all surgeries is higher than WRH, significant difference was found only in cholecystectomy(p<0.05). In both hospitals Ampicillin+Cloxacillin was the most commonly used regimen, 12.4% in WRHand 34% in MTH. In WRH, Ciprofloxacin/Cefotaxim was also used by 12.4%. More than 79.1% of thepatients were exposed to, at least, two antibiotics as a prophylaxis in WRH where as more than 63.0% inMTH. Penicillin was found to be mostly used in both hospitals.Key Words: Antibiotic prophylaxis, Surgery.

Perbedaan sensitivitas tetes telinga antibiotik terhadap Pseudomonas aeruginosa pada otitis media supuratif kronik

2012 ◽  
Vol 42 (2) ◽  
Author(s):  
Anton Budhi Darmawan ◽  
Dwi Utami Anjarwati
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Otitis Media ◽  
Chronic Suppurative Otitis Media ◽  
Test Results ◽  
Sectional Study ◽  
Suppurative Otitis Media ◽  
Number Of Patients ◽  
Significant Difference ◽  
Cochran Test ◽  
Post Hoc

Background: Chronic suppurative otitis media (CSOM) is one infectious disease of the middle ear, most commonly caused by Pseudomonas aeruginosa. A high number of patients come to the ENT outpatient clinic with active benign type of CSOM. The bacteria Pseudomonas aeruginosa is capable of producing biofilm which protects itself from penetration of antibiotics, and therefore creates resistance towards antibiotics and difficult to eradicate. Objective: The aim of this study was to compare the sensitivity levels of chloramphenicol, polymyxin-neomycin, cyprofloxacin and ofloxacine against Pseudomonas aeruginosa in patients with active benign type CSOM in ENT clinic. Method: The method used was across sectional study on 25 patients, from August 2010 until December 2010. Samples were taken withear swab and then put on sensitivity test to chloramphenicol, polymyxin-neomycin, cyprofloxacin andofloxacine using the diffusion disc method. The analysis used in this study was Cochran test. Results: Results showed a significant difference in sensitivity among chloramphenicol (38,70%), polymyxinneomycin(83,87%),cyprofloxacin(90,32%)andofloxacin(58,06%)withp=0,000(p<0,05).PostHocanalysisusing the Mc Nemar indicated that there were significant differences in sensitivity betweenpolymyxin-neomycin to chloramphenicol with p=0,000 (p<0,05), ciprofloxacin to chloramphenicol andciprofloxacin to ofloxacine with p= 0,002, but there were no significant differences between cyprofloxacinto polymyxin-neomycin with p=0,687, polymyxin-neomycin to ofloxacin p=0.057 and ofloxacin tochloramphenicol p=0,109.   There were significant differences in antibiotic ear dropssensitivity to Pseudomonas aeruginosa in patients with active benign type of CSOM. Cyprofloxacin andpolymyxin-neomycin were more sensitive than ofloxacin and chloramphenicol. Keywords: Pseudomonas aeruginosa, active benign type of chronic suppurative otitis media, antibioticear drops.  Abstrak :  Latar belakang: Otitis media supuratif kronik (OMSK) merupakan penyakit infeksi kronik telinga tengah yang sering dijumpai di klinik THT. Penyebab tersering OMSK adalah bakteri Pseudomonasaeruginosa. Pseudomonas aeruginosa mempunyai kemampuan untuk membentuk biofilm yangmelindunginya dari penetrasi antibiotik sehingga menimbulkan resistensi terhadap antibiotik dan sulituntuk eradikasinya. Tujuan: Untuk mengetahui perbandingan tingkat sensitivitas kloramfenikol,polimiksin-neomisin, ciprofloksasin dan ofloksasin terhadap isolat Pseudomonas aeruginosa padapasien OMSK benigna aktif di klinik THT RSMS. Metode: Metode yang digunakan adalah crosssectional terhadap 29 pasien OMSK di klinik THT RSMS periode bulan Agustus 2010 - Desember2010. Pengambilan sampel dilakukan dengan swab telinga. Uji sensitivitas terhadap kloramfenikol,polimiksin-neomisin, ciprofloksasin dan ofloksasin dilakukan dengan metode cakram secara difusi.Analisis yang digunakan dalam penelitian ini adalah Cochran dan analisis post hoc. Hasil: Didapatkansensitivitas kloramfenikol sebesar 38,70%, polimiksin-neomisin sebesar 83,87%, ciprofloksasin sebesar90,32% dan ofloksasin sebesar 58,06% dengan p=0,01 (P<0,05), yang menunjukkan adanya perbedaansensitivitas yang bermakna antara kloramfenikol, polimiksin-neomisin, ciprofloksasin dan ofloksasinterhadap Pseudomonas aeruginosa. Analisis post hoc menggunakan Mc Nemar menunjukkan bahwaterdapat perbedaan sensitivitas yang bermakna antara tetes telinga polimiksin-neomisin terhadapkloramfenikol, dan ciprofloksasin terhadap kloramfenikol p=0,000 (p<0,05), serta terdapat perbedaanyang bermakna antara tetes telinga ciprofloksasin terhadap ofloksasin, p=0,002, tetapi tidak terdapatperbedaan yang bermakna antara ciprofloksasin terhadap polimiksin-neomisin, p=0,687, polimiksinneomisinterhadap ofloksasin p=0,057, dan kloramfenikol terhadap ofloksasin p=0,109. Kesimpulan:Terdapat perbedaan sensitivitas yang bermakna tetes telinga antibiotik terhadap Pseudomonas aeruginosa pada pasien OMSK benigna aktif. Ciprofloksasin dan polimiksin-neomisin tetes telinga mempunyai sensitivitas yang lebih baik dibanding ofloksasin dan kloramfenikol. Kata kunci: Pseudomonas aeruginosa, otitis media supuratif kronik, tetes telinga antibiotik 

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