Recent Insights into the Potential of Magnetic Metal Nanostructures as Magnetic Hyperthermia Agents

2020 ◽  
Vol 18 (12) ◽  
pp. 861-880
Author(s):  
A. R. Aarathy ◽  
M. S. Gopika ◽  
S. Savitha Pillai
Keyword(s):  
Metal Nanoparticles ◽  
Heat Generation ◽  
Magnetic Hyperthermia ◽  
Metal Nanoparticle ◽  
Treatment Modalities ◽  
Metal Nanostructures ◽  
Synthesis Methods ◽  
Promising Alternative ◽  
Heating Efficiency ◽  
Magnetic Metal

The advancements in magnetic nanoparticle mediated hyperthermia give so many optimistic and fruitful results that make it a promising and complementary approach for the existing treatment modalities of cancer. This thermotherapy is gaining wide acceptance among the medical community compared to the conventional treatment methods. The former provides a local heat generation in the malignant tumor cells and remains non-invasive to the adjacent healthy cells. The increased heating efficiency of magnetic nanoparticles and the control of local therapeutic temperature are the main challenges of hyperthermia. Superparamagnetic Iron Oxide nanoparticles have been intensively studied and dominating in magnetic hyperthermia. Recently many researchers successfully demonstrated high heating efficiency and biocompatibility of a wide variety of magnetic metal nanoparticles and proposed as the most promising alternative for traditional iron oxides, which opens up a new avenue for magnetic metal nanoparticles in magnetic hyperthermia. The review presents the recent advancements that occurred in the field of metal nanoparticle mediated magnetic hyperthermia. The theory underlying heat generation, synthesis methods, biofunctionalization, Specific Absorption Rate studies, challenges and future perspectives of magnetic metal nanoparticles are presented. This will inspire more in-depth research and advance practical applications of metal nanoparticles in magnetic hyperthermia.

Surfactant-free solution-based synthesis of metallic nanoparticles toward efficient use of the nanoparticles’ surfaces and their application in catalysis and chemo-/biosensing

2013 ◽  
Vol 2 (1) ◽  
pp. 5-25 ◽  
Author(s):  
Hideya Kawasaki
Keyword(s):  
Metal Nanoparticles ◽  
Metallic Nanoparticles ◽  
Active Sites ◽  
Metal Nanoparticle ◽  
Molar Ratio ◽  
Synthesis Methods ◽  
Ionization Mass ◽  
Free Solution ◽  
Effective Utilization ◽  
Stabilizing Agents

AbstractThe choice of stabilizer and the stabilizer-to-precursor ions molar ratio during metal nanoparticle synthesis are important for controlling the shape, size, and dispersion stability of the nanoparticles. However, the active sites on the nanoparticles surfaces may be blocked by the stabilizing agents used, resulting in a less-than-effective utilization of the surfaces. In this review, various surfactant-free solution-based methods of synthesizing metal nanoparticles are described, along with the applications of such nanoparticles in catalysis and sensing. “Surfactant-free” synthesis does not imply truly bare metal nanoparticles synthesis but implies one where the metal nanoparticles are prepared in the absence of additional stabilizing agents such as thiolate and phosphine compounds, surfactants, and polymers. These metal nanoparticles are stabilized by the solvents or the simple ions of the reducing agents or low-molecular-weight salts used. Surfactant-free synthesis of metal nanoparticles via photochemical-, ultrasonochemical-, and laser ablation-mediated synthesis methods is also described. Because of the effective utilization of their surfaces, metal nanoparticles prepared without surfactants, polymers, templates, or seeds are expected to exhibit high performance when used in catalysis (synthetic catalysis and electrocatalysis) and sensing (surface-enhanced Raman scattering (SERS)), surface-assisted laser desorption/ionization-mass spectrometry (SALDI-MS)).

scholarly journals Current Strategies for Noble Metal Nanoparticle Synthesis

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Giyaullah Habibullah ◽  
Jitka Viktorova ◽  
Tomas Ruml
Keyword(s):  
Noble Metal ◽  
Noble Metals ◽  
Drug Carriers ◽  
Industrial Applications ◽  
Metal Nanoparticle ◽  
Noble Metal Nanoparticles ◽  
Synthesis Methods ◽  
Gold And Silver Nanoparticles ◽  
Diverse Range ◽  
The Past

AbstractNoble metals have played an integral part in human history for centuries; however, their integration with recent advances in nanotechnology and material sciences have provided new research opportunities in both academia and industry, which has resulted in a new array of advanced applications, including medical ones. Noble metal nanoparticles (NMNPs) have been of great importance in the field of biomedicine over the past few decades due to their importance in personalized healthcare and diagnostics. In particular, platinum, gold and silver nanoparticles have achieved the most dominant spot in the list, thanks to a very diverse range of industrial applications, including biomedical ones such as antimicrobial and antiviral agents, diagnostics, drug carriers and imaging probes. In particular, their superior resistance to extreme conditions of corrosion and oxidation is highly appreciated. Notably, in the past two decades there has been a tremendous advancement in the development of new strategies of more cost-effective and robust NMNP synthesis methods that provide materials with highly tunable physicochemical, optical and thermal properties, and biochemical functionalities. As a result, new advanced hybrid NMNPs with polymer, graphene, carbon nanotubes, quantum dots and core–shell systems have been developed with even more enhanced physicochemical characteristics that has led to exceptional diagnostic and therapeutic applications. In this review, we aim to summarize current advances in the synthesis of NMNPs (Au, Ag and Pt).

Experimental and theoretical study of the characteristics of LSPR peaks for metal NPs produced by controlling Ar ambient gas pressure to enhance the efficiency of solar cells

2021 ◽  
pp. 1-6
Author(s):  
Serap Yiğit Gezgin ◽  
Abdullah Kepceoğlu ◽  
Hamdi Şükür Kiliç
Keyword(s):  
Metal Nanoparticles ◽  
Ag Nanoparticles ◽  
Solar Spectrum ◽  
Wavelength Region ◽  
Gas Pressure ◽  
Metal Nanoparticle ◽  
Ag Nanoparticle ◽  
Extinction Cross Section ◽  
Ambient Gas ◽  
Ar Gas

In this study, silver (Ag) nanoparticle thin films were deposited on microscope slide glass and Si wafer substrates using the pulsed-laser deposition (PLD) technique in Ar ambient gas pressures of 1 × 10−3 and 7.5 × 10−1 mbar. AFM analysis has shown that the number of Ag nanoparticles reaching the substrate decreased with increasing Ar gas pressure. As a result of Ar ambient gas being allowed into the vacuum chamber, it was observed that the size and height of Ag nanoparticles decreased and the interparticle distances decreased. According to the absorption spectra taken by a UV–vis spectrometer, the wavelength where the localised surface plasmon resonance (LSPR) peak appeared was shifted towards the longer wavelength region in the solar spectrum as Ar background gas pressure was decreased. This experiment shows that LSPR wavelength can be tuned by adjusting the size of metal nanoparticles, which can be controlled by changing Ar gas pressure. The obtained extinction cross section spectra for Ag nanoparticle thin film was theoretically analysed and determined by using the metal nanoparticle–boundary element method (MNPBEM) toolbox simulation program. In this study, experimental spectrum and simulation data for metal nanoparticles were acquired, compared, and determined to be in agreement.

scholarly journals Optimization of transition metal nanoparticle-phosphonium ionic liquid composite catalytic systems for deep hydrogenation and hydrodeoxygenation reactions

2015 ◽  
Vol 17 (3) ◽  
pp. 1597-1604 ◽  
Author(s):  
Abhinandan Banerjee ◽  
Robert W. J. Scott
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Transition Metal ◽  
Metal Nanoparticles ◽  
Metal Nanoparticle ◽  
Catalytic Systems ◽  
Phosphonium Ionic Liquid

Stable metal nanoparticles in tetraalkylphosphonium ionic liquids can catalyze hydrogenations, as well as phenol hydrodeoxygenation, owing to presence of adventitious borates.

scholarly journals Application of biosynthesized metal nanoparticles in electrochemical sensors

2021 ◽  
pp. 77-77
Author(s):  
Totka Dodevska ◽  
Dobrin Hadzhiev ◽  
Ivan Shterev ◽  
Yanna Lazarova
Keyword(s):  
Green Synthesis ◽  
Metal Nanoparticles ◽  
Electrochemical Sensors ◽  
Dynamic Range ◽  
Limit Of Detection ◽  
Cost Effective ◽  
Electrochemical Sensing ◽  
Synthesis Methods ◽  
Range Limit ◽  
Wide Range

Recently, the development of eco-friendly, cost-effective and reliable methods for synthesis of metal nanoparticles has drawn a considerable attention. The so-called green synthesis, using mild reaction conditions and natural resources as plant extracts and microorganisms, has established as a convenient, sustainable, cheap and environmentally safe approach for synthesis of a wide range of nanomaterials. Over the past decade, biosynthesis is regarded as an important tool for reducing the harmful effects of traditional nanoparticle synthesis methods commonly used in laboratories and industry. This review emphasizes the significance of biosynthesized metal nanoparticles in the field of electrochemical sensing. There is increasing evidence that green synthesis of nanoparticles provides a new direction in designing of cost-effective, highly sensitive and selective electrode-catalysts applicable in food, clinical and environmental analysis. The article is based on 157 references and provided a detailed overview on the main approaches for green synthesis of metal nanoparticles and their applications in designing of electrochemical sensor devices. Important operational characteristics including sensitivity, dynamic range, limit of detection, as well as data on stability and reproducibility of sensors have also been covered. Keywords: biosynthesis; green synthesis; nanomaterials; nanotechnology; modified electrodes

Hierarchical Lichee-like Fe3O4 Assemblies and Their High Heating Efficiency in Magnetic Hyperthermia

2021 ◽  
Author(s):  
Wen-Yu Li ◽  
Wen-Tao Li ◽  
Bang-Quan Li ◽  
Li-Juan Dong ◽  
Tian-Hua Meng ◽  
...  
Keyword(s):  
Magnetic Hyperthermia ◽  
Heating Efficiency ◽  
High Heating

Localized Laser Sintering of Metal Nanoparticle Inks Printed with Aerosol Jet® Technology for Flexible Electronics

2017 ◽  
Vol 14 (4) ◽  
pp. 132-139 ◽  
Author(s):  
Michael J. Renn ◽  
Matthew Schrandt ◽  
Jaxon Renn ◽  
James Q. Feng
Keyword(s):  
Metal Nanoparticles ◽  
Flexible Electronics ◽  
Low Cost ◽  
Damage Threshold ◽  
Laser Sintering ◽  
Heating Time ◽  
Metal Nanoparticle ◽  
Polymer Materials ◽  
Nanoparticle Inks ◽  
Short Heating Time

Direct-write methods, such as the Aerosol Jet® technology, have enabled fabrication of flexible multifunctional 3-D devices by printing electronic circuits on thermoplastic and thermoset polymer materials. Conductive traces printed by additive manufacturing typically start in the form of liquid metal nanoparticle inks. To produce functional circuits, the printed metal nanoparticle ink material must be postprocessed to form conductive metal by sintering at elevated temperature. Metal nanoparticles are widely used in conductive inks because they can be sintered at relatively low temperatures compared with the melting temperature of bulk metal. This is desirable for fabricating circuits on low-cost plastic substrates. To minimize thermal damage to the plastics, while effectively sintering the metal nanoparticle inks, we describe a laser sintering process that generates a localized heat-affected zone (HAZ) when scanning over a printed feature. For sintering metal nanoparticles that are reactive to oxygen, an inert or reducing gas shroud is applied around the laser spot to shield the HAZ from ambient oxygen. With the shroud gas-shielded laser, oxygen-sensitive nanoparticles, such as those made of copper and nickel, can be successfully sintered in open air. With very short heating time and small HAZ, the localized peak sintering temperature can be substantially higher than that of damage threshold for the underlying substrate, for effective metallization of nanoparticle inks. Here, we demonstrate capabilities for producing conductive tracks of silver, copper, and copper–nickel alloys on flexible films as well as fabricating functional thermocouples and strain gauge sensors, with printed metal nanoparticle inks sintered by shroud-gas-shielded laser.

Synthesis and Antimicrobial Properties of Zinc Oxide Nanoparticles

2020 ◽  
Vol 20 (10) ◽  
pp. 5977-5996 ◽  
Author(s):  
Saee Gharpure ◽  
Balaprasad Ankamwar
Keyword(s):  
Zinc Oxide ◽  
Zno Nanoparticles ◽  
Zinc Oxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
Physical Contact ◽  
Oxide Nanoparticles ◽  
Synthesis Methods ◽  
Promising Alternative

With increase in incidence of multidrug resistant pathogens, there is a demand to adapt newer approaches in order to combat these diseases as traditional therapy is insufficient for their treatment. Use of nanotechnology provides a promising alternative as antimicrobial agents as against traditional antibiotics. Metal oxides have been exploited for a long times for their antimicrobial properties. Zinc oxide nanoparticles (ZnO NPs) are preferred over other metal oxide nanoparticles because of their bio-compatible nature and excellent antibacterial potentials. The basic mechanism of bactericidal nature of ZnO nanoparticles includes physical contact between ZnO nanoparticles and the bacterial cell wall, generation of reactive oxygen species (ROS) as well as free radicals and release of Zn2+ ions. This review focuses on different synthesis methods of ZnO nanoparticles, various analytical techniques frequently used for testing antibacterial properties, mechanism explaining antibacterial nature of ZnO nanoparticles as well as different factors affecting the antibacterial properties.

scholarly journals Role of zinc substitution in magnetic hyperthermia properties of magnetite nanoparticles: interplay between intrinsic properties and dipolar interactions

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Yaser Hadadian ◽  
Ana Paula Ramos ◽  
Theo Z. Pavan
Keyword(s):  
Magnetic Nanoparticles ◽  
Magnetite Nanoparticles ◽  
Linear Response Theory ◽  
Magnetic Hyperthermia ◽  
Superior Performance ◽  
Dipolar Interactions ◽  
Intrinsic Properties ◽  
Specific Loss ◽  
Heating Efficiency ◽  
Specific Loss Power

AbstractOptimizing the intrinsic properties of magnetic nanoparticles for magnetic hyperthermia is of considerable concern. In addition, the heating efficiency of the nanoparticles can be substantially influenced by dipolar interactions. Since adequate control of the intrinsic properties of magnetic nanoparticles is not straightforward, experimentally studying the complex interplay between these properties and dipolar interactions affecting the specific loss power can be challenging. Substituting zinc in magnetite structure is considered as an elegant approach to tune its properties. Here, we present experimental and numerical simulation results of magnetic hyperthermia studies using a series of zinc-substituted magnetite nanoparticles (ZnxFe1-xFe2O4, x = 0.0, 0.1, 0.2, 0.3 and 0.4). All experiments were conducted in linear regime and the results were inferred based on the numerical simulations conducted in the framework of the linear response theory. The results showed that depending on the nanoparticles intrinsic properties, interparticle interactions can have different effects on the specific loss power. When dipolar interactions were strong enough to affect the heating efficiency, the parameter σ = KeffV/kBT (Keff is the effective anisotropy and V the volume of the particles) determined the type of the effect. Finally, the sample x = 0.1 showed a superior performance with a relatively high intrinsic loss power 5.4 nHm2kg−1.

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