scholarly journals Does Parental Co-creation Impacts Perceived Value? A Mixed-method Study in Indian Elementary Educational Innovations

2019 ◽  
Vol 24 (1) ◽  
pp. 90-100
Author(s):  
Meeta Dasgupta ◽  
Anupama Prashar
Keyword(s):  
Critical Role ◽  
Perceived Value ◽  
Primary Role ◽  
Educational Effectiveness ◽  
Educational Innovations ◽  
School Services ◽  
Business Units ◽  
Role Of Parents ◽  
The Impact

Research on building innovative practices for enhancing the educational effectiveness has gained momentum. Schools as business units play a critical role in building effectiveness. Empirical investigation on the role of parents, the primary customers taking decisions with respect to availing school services for their children, as co-creators in conceptualizing and executing educational innovations is thin. To bridge this research gap, a mixed methods study was conducted on a sample of elementary schools in India. The study also investigated the impact of parents’ involvement on their perceived value and satisfaction. The results suggested that schools are undertaking various innovative initiatives in which parents play a primary role in execution both at home and in the school. It was found that parents’ perception of value for innovative practices introduced by the schools is high, irrespective of their low involvement in the conceptualization stage. The findings also indicated that parental involvement in the execution stage of the initiatives impacts their perceived value more than at the conceptualization stage.

scholarly journals NLRP7 Promotes Choriocarcinoma Growth and Progression through the Establishment of an Immunosuppressive Microenvironment

Cancers ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 2999
Author(s):  
Deborah Reynaud ◽  
Roland Abi Nahed ◽  
Nicolas Lemaitre ◽  
Pierre-Adrien Bolze ◽  
Wael Traboulsi ◽  
...  
Keyword(s):  
Immune Response ◽  
Tumor Cells ◽  
Major Gene ◽  
Critical Role ◽  
Orthotopic Model ◽  
Independent Manner ◽  
Maternal Immune Response ◽  
The Impact

The inflammatory gene NLRP7 is the major gene responsible for recurrent complete hydatidiform moles (CHM), an abnormal pregnancy that can develop into gestational choriocarcinoma (CC). However, the role of NLRP7 in the development and immune tolerance of CC has not been investigated. Three approaches were employed to define the role of NLRP7 in CC development: (i) a clinical study that analyzed human placenta and sera collected from women with normal pregnancies, CHM or CC; (ii) an in vitro study that investigated the impact of NLRP7 knockdown on tumor growth and organization; and (iii) an in vivo study that used two CC mouse models, including an orthotopic model. NLRP7 and circulating inflammatory cytokines were upregulated in tumor cells and in CHM and CC. In tumor cells, NLRP7 functions in an inflammasome-independent manner and promoted their proliferation and 3D organization. Gravid mice placentas injected with CC cells invalidated for NLRP7, exhibited higher maternal immune response, developed smaller tumors, and displayed less metastases. Our data characterized the critical role of NLRP7 in CC and provided evidence of its contribution to the development of an immunosuppressive maternal microenvironment that not only downregulates the maternal immune response but also fosters the growth and progression of CC.

scholarly journals Adolescence as a “critical period” in the heritage language use. Polish in Germany

2021 ◽  
Vol 7 (1) ◽  
pp. 301-315
Author(s):  
Hanna Pułaczewska
Keyword(s):  
Role Models ◽  
Personal Development ◽  
Critical Period ◽  
Growing Up ◽  
Age Related ◽  
The Media ◽  
Role Of Parents ◽  
Qualitative Part ◽  
The Impact

Abstract In the article, we consider the impact of adolescence upon the usage of Polish in Polish-German bilinguals raised and living in Germany and demonstrate how adolescence surfaces as a socially based “critical period” in this usage using results from a survey and interviews conducted with 30 teenagers. In the quantitative part of the study, we seek to establish whether adolescents’ age affected the pattern and quantity of their usage of Polish in the media and contacts with age peers, whether the latter two facets of growing up with Polish were interrelated, and which other factors affected peer-relevant activities in Polish. Both age and peer contact turned out to significantly affect the use of the media in Polish, while peer contact in Polish was affected by the parental use of Polish in parent-child communication. The qualitative part presents the context and motivation for using Polish by the youths in peer-relevant activities. We integrate the results with insights provided by child development psychology from the perspective of language socialisation theory and interpret the age-related decline of interest in the Polish media as an effect of a diminishing role of parents and the increasing role of age peers as role models in personal development.

scholarly journals Specialized Pro-Resolving Lipid Mediators in Neonatal Cardiovascular Physiology and Diseases

Antioxidants ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 933
Author(s):  
Andrea Gila-Diaz ◽  
Gloria Herranz Carrillo ◽  
Pratibha Singh ◽  
David Ramiro-Cortijo
Keyword(s):  
Tissue Repair ◽  
Cardiovascular Health ◽  
Critical Role ◽  
Potential Effect ◽  
Lipid Mediators ◽  
Physiological Effects ◽  
Therapeutic Approaches ◽  
The Impact ◽  
Long Chain

Cardiovascular disease remains a leading cause of mortality worldwide. Unresolved inflammation plays a critical role in cardiovascular diseases development. Specialized Pro-Resolving Mediators (SPMs), derived from long chain polyunsaturated fatty acids (LCPUFAs), enhances the host defense, by resolving the inflammation and tissue repair. In addition, SPMs also have anti-inflammatory properties. These physiological effects depend on the availability of LCPUFAs precursors and cellular metabolic balance. Most of the studies have focused on the impact of SPMs in adult cardiovascular health and diseases. In this review, we discuss LCPUFAs metabolism, SPMs, and their potential effect on cardiovascular health and diseases primarily focusing in neonates. A better understanding of the role of these SPMs in cardiovascular health and diseases in neonates could lead to the development of novel therapeutic approaches in cardiovascular dysfunction.

scholarly journals Program Sekolah dalam Upaya Pencegahan NAPZA

2019 ◽  
Vol 14 (1) ◽  
pp. 39-49
Author(s):  
Fidrayani Fidrayani ◽  
Desiana Utami
Keyword(s):  
Extracurricular Activities ◽  
Negative Impact ◽  
Drug Prevention ◽  
Problem Solver ◽  
Drug Abuse Prevention ◽  
School Rules ◽  
Role Of Parents ◽  
Problem Solvers ◽  
The Impact

Abstract. Narcotics in unattended use can have a negative impact. The impact is potential to destroy the youth generation. It is necessary to hold the drug prevention programs, especially in schools as one of ways to prevent the widespread negative impact. The prevention can be through the role of parents, teachers and stakeholders as part of the community. The teachers’ role is divided into four sub-role, namely as educators, as advisors, as mentors, and particularly as problem solvers. The role of teachers certainly will not have power if it is not supported by the role of schools. Effots that are conducted by school stakeholder are as follow: a) compose the school rules; b) conduct inspections intensively and spontaneously; c) cooperate with related institutions for counseling and socialization; d) utilize extracurricular activities as means of prevention; e) integrate drug awareness into learning curriculum; (f) maximize the tasks as the effort of drug abuse prevention. Expectedly, these drug prevention efforts can be implemented by all schools as one of ways to prevent the destruction of the nation through NAPZA. Abstrak. Narkoba dalam penggunaan yang tidak diawasi dapat menimbulkan dampak negatif. Dampak tersebut tidak menutup kemungkinan dapat merusak generasi muda. Salah satu cara agar bahaya tersebut tidak meluas dampaknya, maka perlu program pencegahan terutama di sekolah. Pencegahan tersebut dapat melalui peran orang tua, guru dan pemangku kebijakan sebagai bagian dari masyarakat. Peran guru dibagi dalam empat yakni sebagai pendidik, penasehati, pembimbing dan lebih utama lagi sebagai problem solver. Peran guru ini tentu tidak akan memiliki kekuatan jika tidak didukung oleh peran sekolah. Upaya yang dilakukan oleh pihak sekolah adalah a) membuat tata tertib sekolah, b) melakukan razia intensif dan spontan, c) bekerjasama dengan instansi terkait guna penyuluhan dan sosialisasi, d) menggunakan ekstrakurikuler sebagai sarana pencegahan, e) memasukkan materi tentang narkotika ke dalam kurikulum pengajaran, f) memaksimalkan tugas dalam upaya pencegahan penyalahgunaan NAPZA. Diharapkan agar upaya pencegahan tersebut dapat diikuti oleh semua sekolah sebagai salah satu usaha untuk mencegah rusaknya anak bangsa melalui NAPZA. 

scholarly journals COVID-19 as an “Infodemic” in Public Health: Critical Role of the Social Media

2021 ◽  
Vol 9 ◽  
Author(s):  
Debanjan Banerjee ◽  
K. S. Meena
Keyword(s):  
Public Health ◽  
Social Media ◽  
Critical Role ◽  
Global Public Health ◽  
Sources Of Information ◽  
Multiple Sources ◽  
Health Crisis ◽  
Digital Platforms ◽  
The Impact

The Coronavirus disease 2019 (COVID-19) pandemic has emerged as a significant and global public health crisis. Besides the rising number of cases and fatalities, the outbreak has also affected economies, employment and policies alike. As billions are being isolated at their homes to contain the infection, the uncertainty gives rise to mass hysteria and panic. Amidst this, there has been a hidden epidemic of “information” that makes COVID-19 stand out as a “digital infodemic” from the earlier outbreaks. Repeated and detailed content about the virus, geographical statistics, and multiple sources of information can all lead to chronic stress and confusion at times of crisis. Added to this is the plethora of misinformation, rumor and conspiracy theories circulating every day. With increased digitalization, media penetration has increased with a more significant number of people aiding in the “information pollution.” In this article, we glance at the unique evolution of COVID-19 as an “infodemic” in the hands of social media and the impact it had on its spread and public reaction. We then look at the ways forward in which the role of social media (as well as other digital platforms) can be integrated into social and public health, for a better symbiosis, “digital balance” and pandemic preparedness for the ongoing crisis and the future.

scholarly journals THE ROLE OF PARENTS IN BOLO VILLAGE IN SUPPORTING DISTANCE LEARNING DURING THE COVID-19 PANDEMIC

2021 ◽  
Vol 4 (2) ◽  
pp. 69-75
Author(s):  
Ida Mawaddah ◽  
Zulhafriliya Zulhafriliya ◽  
Sudarsono Sudarsono
Keyword(s):  
Distance Learning ◽  
Junior High School ◽  
Healthy Lifestyle ◽  
Family Values ◽  
Learning Approaches ◽  
School Aged Children ◽  
Distant Learning ◽  
Role Of Parents ◽  
The Impact

The Indonesian government was concerned about the impact of a wider spread of Covid-19, so it moved quickly to break the chain of transmission by urging people to live a healthy lifestyle, avoid crowds, and keep a safe distance. As a result, the circumstance has a significant impact on education and learning. The goal of this study is to learn more about the role of parents in promoting distant learning and to identify the characteristics that encourage and limit distance learning in Bolo Village during the Covid-19 outbreak. Students are forced to study from home due to government regulations. Teachers can ensure students' learning activities in a variety of ways, one of which is by involving parents as the primary companion of students when they are at home. The participants in this study were parents and their junior high school-aged children. The information was gathered through organized interviews utilizing the researcher's prepared questions. The data in this study was analyzed utilizing qualitative data analysis approaches such as the Miles and Huberman model, which features a cycle that includes data reduction, data presentation, verification, and conclusion drafting. According to the findings of this study, parents in Bolo Village played four roles in supporting learning from home during the Covid-19 pandemic: 1) accompanying children in learning, 2) intense communication with children, 3) providing supervision to children, and 4) educating and supporting children motivation. The supporting variables discovered are: 1) responsibility, 2) family values, and 3) availability to satisfy the needs of children. There are also barriers, such as 1) internet network issues, 2) too much workload, and 3) boring and less diversified learning approaches.

scholarly journals Paracrine interactions between epithelial cells promote colon cancer growth

2020 ◽  
Author(s):  
Guillaume Jacquemin ◽  
Annabelle Wurmser ◽  
Mathilde Huyghe ◽  
Wenjie Sun ◽  
Meghan Perkins ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Cancer Cells ◽  
Stromal Cells ◽  
Critical Role ◽  
Essential Factor ◽  
Transcriptional Responses ◽  
Tumour Formation ◽  
Different Types ◽  
The Impact

AbstractTumours are complex ecosystems composed of different types of cells that communicate and influence each other. While the critical role of stromal cells in affecting tumour growth is well established, the impact of mutant cancer cells on healthy surrounding tissues remains poorly defined. Here, we uncovered a paracrine mechanism by which intestinal cancer cells reactivate foetal and regenerative Yap-associated transcriptional programs in neighbouring wildtype epithelial cells, rendering them adapted to thrive in the tumour context. We identified the glycoprotein Thrombospondin-1 (Thbs1) as the essential factor that mediates non-cell autonomous morphological and transcriptional responses. Importantly, Thbs1 is associated with bad prognosis in several human cancers. This study reveals the Thbs1-YAP axis as the mechanistic link mediating paracrine interactions between epithelial cells, promoting tumour formation and progression.

scholarly journals PERAN ORANG TUA DALAM PERTUMBUHAN SPIRITUALITAS ANAK: SEBUAH STUDI EKSEGETIS EFESUS 6:1-4

2018 ◽  
Vol 4 (2) ◽  
pp. 116-129
Author(s):  
Waharman Waharman
Keyword(s):  
Spiritual Growth ◽  
Sunday School ◽  
Early Age ◽  
School Services ◽  
The Family ◽  
Role Of Parents ◽  
The Church

The role of parents for their children in spiritual growth is very important, and starting from an early age, teaching for children's spiritual growth is not only given to the church, or during Sunday school services but the most important and most important is the role of parents in the family for her children. If noted, there are still many parents who do not realize the importance of their role as parents to educate the spiritual growth of their children. Therefore through this paper, we try to remind the important role of parents in the growth of children.

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