scholarly journals Could information about herd immunity help us achieve herd immunity? Evidence from a population representative survey experiment

2018 ◽  
Vol 46 (8) ◽  
pp. 854-858 ◽  
Author(s):  
Sveinung Arnesen ◽  
Kristine Bærøe ◽  
Cornelius Cappelen ◽  
Benedicte Carlsen
Keyword(s):  
Survey Design ◽  
Herd Immunity ◽  
Control Group ◽  
Health Campaigns ◽  
Treatment Groups ◽  
Hypothetical Scenario ◽  
Concern For Others ◽  
Public Health Campaigns ◽  
The One ◽  
The Individual

Aims: Immunisation causes dramatic reductions in morbidity and mortality from infectious diseases; however, resistance to vaccination is nonetheless widespread. An understudied issue – explored here – is whether appeals to collective as opposed to individual benefits of vaccination encourage people to vaccinate. Knowledge of this is important not least with respect to the design of public health campaigns, which often lack information about the collective benefits of vaccination. Methods: Using a between-subjects experimental survey design, we test whether information about the effects of herd immunity influences people’s decision to vaccinate. A representative sample of Norwegians was confronted with a hypothetical scenario in which a new and infectious disease is on its way to Norway. The sample was split in three – a control group and two treatment groups. The one treatment group was provided information about collective benefits of vaccination; the other was provided information about the individual benefits of vaccination. Results: Both treatments positively affect people’s decision to vaccinate; however, informing about the collective benefits has an even stronger effect than informing about the individual benefits. Conclusions: Our results suggest that people’s decision about whether to vaccinate and thus contribute to herd immunity is influenced by concern for others. Thus, stressing the collective benefits of vaccination could increase the effectiveness of health campaigns.

scholarly journals Vascular Endothelial Growth Factor Concentration in Brain of Rat Treated with Anaerobic Exercises

2015 ◽  
Vol 4 (3) ◽  
pp. 201
Author(s):  
Rostika Flora ◽  
Muhammad Zulkarnain ◽  
Yuliana Ardi ◽  
Esti Sorena ◽  
Roslina Wati ◽  
...  
Keyword(s):  
Wistar Rat ◽  
Anaerobic Exercise ◽  
Control Group ◽  
Vascular Endothelial ◽  
Exercise Frequency ◽  
Treatment Groups ◽  
The One ◽  
Short Time ◽  
Endothelial Growth Factor ◽  
Brain Tissues

Anaerobic  exercise is a high-intensity exercise that needs quick energy supplies obtained in a very short time. However, this exercise may result in tissue hypoxia which is characterized by the increase of HIF-1α concentration. The presence of HIF-1α will induce the secretion of VEGF and, eventually, trigger angiogenesis. Nevertheless, it is still unclear whether anaerobic exercise will also cause hypoxia in which this condition will increase the concentration of VEGF in brain tissues. The aim of this study was to find out the effect of anaerobic exercise frequency towards VEGF concentration of Wistar rat brain tissues.  Brain tissues were taken from rats treated with anaerobic exercise using treadmill. This exercise was given in different frequencies; one time, three times, and seven times a week.  The data collected were analyzed using independent t-test. The results of this study showed that anaerobic  exercise done once a week could significantly increase VEGF concentration (p < 0.05) if compared with the one in control group (95.21 ± 31.99 v.s. 63.36 ± 11.01 pg/mL). Meanwhile, VEGF concentration of treatment groups given exercise three times a week (47.97 ± 10.68 pg/mL) and seven times a week (40.56 ± 13.98 pg/mL) showed a significant decrease if compared with that of control group (63.36 ± 11.01 pg/mL). Anaerobic  exercise affected VEGF concentration as an indicator of angiogenesis in brain tissue of wistar rats.

scholarly journals Mutant P53 Expression Of Oral Transformed Epithelium Cell In Rats Injected By Benzo[A]Pyrene

2020 ◽  
Vol 9 (1) ◽  
pp. 85-92
Author(s):  
Sawitri Dwi indah Pertami ◽  
I Ketut Sudiana ◽  
Theresia Indah Budhy ◽  
Retno Palupi ◽  
Ira Arundina
Keyword(s):  
Cell Transformation ◽  
Control Group ◽  
Mutant P53 ◽  
P53 Expression ◽  
Dna Mutation ◽  
Treatment Groups ◽  
Epithelium Cell ◽  
Polycyclic Aromatic ◽  
The One ◽  
Epithelium Cells

Benzopyrene is a polycyclic aromatic hydrocarbons (PAHs) compound that can cause transformation of normal cells into malignant in order to its genotoxic,mutagenic,and carsinogenic ability.  DNA mutation in tumor suppressor genes p53 make cells immortal which results in cell transformation and develops into malignancies. This study consist of five groups including the control group (without benzopyrene injection) and 4 treatment groups injected with benzopyrene each for 4 weeks (P1), 6 weeks (P2), 8 weeks (P3) and 10 weeks (P4).  Therefore, the mutant p53 expression was calculated and analyzed statistically with the One Way Anova Test. There was signifficance difference in mutant p53 expression of oral transformed epithelium cell injected by benzopyrene (p=0.000) and the highest expression was at 10th week. It can be concluded that the mutant P53 expression of oral transformed epithelium cells in rats was increased after injected by benzopyrene

Effects on Gingivitis of Two Different 0.4% SnF2 Gels

1988 ◽  
Vol 67 (2) ◽  
pp. 503-507 ◽  
Author(s):  
R.L. Boyd ◽  
P.J. Leggott ◽  
P.B. Robertson
Keyword(s):  
Treatment Group ◽  
High Availability ◽  
Plaque Index ◽  
Control Group ◽  
Bleeding Tendency ◽  
Gingival Index ◽  
Periodontal Health ◽  
Pocket Depth ◽  
Treatment Groups ◽  
The One

For nine months we monitored the periodontal health of 81 adolescents undergoing orthodontic treatment with fixed appliances, to determine whether daily use of a brush-on 0.4% SnF 2 gel would be better than toothbrushing alone in maintaining periodontal health in these patients, and whether a gel supplying a high percentage of available Sn2+ ion would be more beneficial than a gel supplying a low percentage of available Sn2+ ion. The subjects were matched for age and sex and placed into a control group, which used toothbrushing alone, and two treatment groups, which used toothbrushing supplemented with daily use of a SnF2 gel. One treatment group used a gel with 98% available Sn2+ ion twice daily for the entire nine months. The other treatment group used a gel with less than 2% available Sn2+ once a day for six months, then twice a day for the remaining three months of the study. Clinical assessments (Plaque Index, Gingival Index, Bleeding Tendency, pocket depth, and coronal staining) were made before appliances were placed and at one, three, six, and nine months after appliances were placed. Results indicated that the group using the high-availability Sn 2+ gel twice daily had significantly lower Gingival Index and Bleeding Tendency scores at the one-, three-, six-, and nine-month examinations than did the control group. The group using the low-availability Sn2+ gel showed no significant differences in these assessments from the control group. Neither treatment group showed significant differences from the control group in Plaque Index or pocket depth. In the group using the high-availability Sn2+ gel, one subject developed mild coronal staining, and two developed moderate staining.

scholarly journals Combined effect ofLactobacillus acidophilusandβ-cyclodextrin on serum cholesterol in pigs

2015 ◽  
Vol 115 (1) ◽  
pp. 1-5 ◽  
Author(s):  
L. Alonso ◽  
J. Fontecha ◽  
P. Cuesta
Keyword(s):  
Treatment Group ◽  
Serum Cholesterol ◽  
Ldl Cholesterol ◽  
Combined Treatment ◽  
Combined Effect ◽  
Total Serum ◽  
Control Group ◽  
Total Serum Cholesterol ◽  
Treatment Groups ◽  
The Individual

AbstractA total of twenty-four Yorkshire gilt pigs of 6–7 weeks of age were used in a 2×2 factorial experiment to determine the individual and combined effects of the inclusion of two dietary factors (cholesterol rich, 3 %β-cyclodextrin (BCD) andLactobacillus acidophiluscultures) on total cholesterol and LDL-cholesterol levels in blood serum. Pigs were assigned randomly to treatment groups (n6). Total serum cholesterol concentrations decreased after 3 weeks in all the experimental treatment groups, including diets with BCD,L.acidophilusor both. Similar trends were observed for serum LDL-cholesterol concentrations among the experimental treatments. No statistically significant differences from the control group were observed in either total serum cholesterol or LDL-cholesterol concentrations (P<0·05) for each of the individual treatment groups: BCD orL.acidophilus. However, significant differences in total serum cholesterol concentrations were observed when comparing the combined treatment group (BCD andL.acidophilus) with the control group, which consisted of a basal diet and sterile milk. The combined treatment group exhibited 17·9 % lower total serum cholesterol concentration after 3 weeks. Similar significant differences were observed when comparing the combined effect experimental group with the control group after 3 weeks. The combined treatment group exhibited 27·9 % lower serum LDL-cholesterol concentrations.

scholarly journals The effect of exposure to liquid air freshener on histological of the bronchial mice (Mus musculus)

2021 ◽  
Vol 6 (02) ◽  
Author(s):  
Warobi Warobi ◽  
Delima Engga Maretha ◽  
Asnilawati Asnilawati ◽  
Mashuri Masri
Keyword(s):  
Mus Musculus ◽  
The Body ◽  
Control Group ◽  
Epithelial Tissue ◽  
Treatment Groups ◽  
Histological Picture ◽  
Randomized Design ◽  
Post Test ◽  
The One ◽  
Post Hoc

Air fresheners are products that contain chemicals aimed at reducing unpleasant odours in confined spaces. The use of synthetic air fresheners turns out to harm health because some of their leased Volatile Organic Compounds are classified as toxic compounds and are carcinogens. Air freshener enters the body through the inhalation process in the respiratory system. Modern air fresheners are available in liquid (aerosol) and gel forms. Air fresheners contain addictive substances and solvents such as 1,4-dichlorobenzene which can affect pulmonary function. The purpose of this study is to know the effect of exposure to liquid air freshener on the histology of bronchi of mice (Mus musculus). This study used 20 male mice (Mus musculus) consisting of 4 treatments with 5 replications. The research design is true experimental in the form of a post-test only control group with Completely Randomized Design (CRD). The post-test was done by observing the histological picture of the mice's bronchi after exposure to liquid air freshener given 3x/day for a period of P1 = 2 weeks, P2 = 4 weeks and P3 = 6 weeks. Quantitative data on bronchial histology was tested using the One Way ANOVA statistical test followed by the Post Hoc Tukey test. The results of the study found changes in the histology of the bronchi, thickening of the epithelial tissue of mice. Analysis of comparative data between the control and treatment groups statistically obtained p = 0.010 <0.05, meaning that there was a significant effect and change in the bronchial tubes exposed to liquid air freshener. Histologically there were differences in histology between the control and treatment groups. It was concluded that liquid air freshener had a significant effect on the histological picture of the mice's bronchi.

scholarly journals ADDITION OF WHITE SHRIMP (Penaeus merguiensis) HEAD EXTRACT TO INCREASE PROTEIN CONTENT IN SHRIMP STICKS

2016 ◽  
Vol 2 (1) ◽  
pp. 15-21
Author(s):  
Rabiatul Adawyah
Keyword(s):  
Treatment Group ◽  
Protein Content ◽  
White Shrimp ◽  
Control Group ◽  
Treatment Groups ◽  
Randomized Design ◽  
Increase Protein Content ◽  
Shrimp Head ◽  
The One ◽  
Shrimp Heads

The objective of this study was to obtain a proper ratio between the volume of water and the weight of shrimp heads in order to increase the protein content in shrimp sticks. The design used in the study was a completely randomized design (CRD) with treatment groups of 1:1, 1:2, and a control group without the addition of shrimp head extract. Water content, protein content, ash content and organoleptic test were the parameters measured. The results of the study show that the addition of white shrimp head extract in the treatment group with a 1: 1 ratio produced shrimp sticks with a protein content of 12.22%; in the treatment group with a 1: 2 ratio 13.44%; and in the control group without the addition of shrimp head extract only 5.54%. The addition of shrimp head extract also produced more preferred flavor compared to the one without the addition of the extract.

What Is an Enlightenment Film?Cinema and the Rhetoric of Social Hygiene in Interwar Germany

2015 ◽  
Vol 39 (1) ◽  
pp. 107-127 ◽  
Author(s):  
Andreas Killen
Keyword(s):  
Venereal Disease ◽  
Health Campaigns ◽  
Public Officials ◽  
Social Hygiene ◽  
The Public ◽  
New Ideas ◽  
Public Health Campaigns ◽  
The One ◽  
Nazi Era ◽  
Sexual Enlightenment

This paper examines the discursive production of risk and its management in the German “enlightenment film” of the interwar period. From the sexual enlightenment films of the immediate postwar era to the Nazi-era sterilization films, public health campaigns mobilized new ideas about hygiene and the new resources of the mass media. Depicting a world composed of discrete risks (venereal disease, hereditary illness), on the one hand, and supplying information on how to manage such risks, on the other, public officials and experts invested considerable resources in this project of public education. Yet insofar as this project addressed controversial aspects of human behavior, and often proposed controversial solutions, this campaign of state-sponsored enlightenment remained an ambivalent one. Particularly in campaigns against venereal disease, leading advocates were frequently drawn into debates both about film's value as medium of mass instruction and the nature of the public they sought to address, a public perceived in fundamental ways as “at risk.” Their efforts routinely provoked charges that enlightenment films on sexual conduct could incite the very behaviors they strove to warn audiences against. By the end of the 1920s, the hopes placed in public enlightenment campaigns seemed to have waned. And yet the enlightenment film underwent a significant revival during the Nazi era. The paper concludes by examining the interconnections between the Nazis' reconceptualization of public enlightenment, risk, and strategies for managing it.

scholarly journals Exploration of attitudes regarding uptake of COVID-19 vaccines among vaccine hesitant adults in the UK: A qualitative analysis.

2021 ◽  
Author(s):  
Sarah Denford ◽  
Fiona Mowbray ◽  
Lauren Towler ◽  
Helena Wehling ◽  
Gemma Lasseter ◽  
...  
Keyword(s):  
Vaccine Uptake ◽  
Health Campaigns ◽  
Structured Interviews ◽  
First Results ◽  
Understanding Of Science ◽  
The Government ◽  
Public Health Campaigns ◽  
The Individual ◽  
The Uk

Abstract Background The aim of this work was to explore barriers and facilitators to uptake of COVID-19 vaccines and to explore views and reactions to efforts to improve vaccine uptake among those who were vaccine hesitant. Methods Semi-structured interviews were conducted with people between the age of 18-29 years who had not had a COVID-19 vaccine, and those between 30-49 years who have not received a second dose of a COVID-19 vaccine (more than 12 weeks after receiving a first). Results A total of 70 participants took part in the study, 35 participants had received one dose of the vaccine, and 35 had not received any vaccine. Participants described a possible willingness to be vaccinated to keep themselves and those around them safe, and to avoid restrictions and return to normal. Barriers to uptake included: 1) perceived lack of need for COVID-19 vaccinations, 2) concerns about the efficacy of vaccinations, 3) concerns about safety 4) access. Uptake appeared to be influenced by the age and health status of the individual, trust in government and knowledge and understanding of science. Introduction of vaccine passes may provide a motive for having a vaccine but may also be viewed as coercive. Conclusion Participants were hesitant, rather than opposed, and had questions about their need for, and the safety and efficacy of the vaccine. Young people did not consider themselves to be at risk of becoming ill from COVID-19, did not think the vaccination was effective in preventing infection and transmission, and did not think sufficient research had been conducted with regard to the possible long-term side-effects. These concerns were exacerbated by a lack of trust in the government and misunderstanding of science. In order to promote uptake, public health campaigns should focus on the provision of information from trusted sources that carefully explains the benefits of vaccination and addresses safety concerns more effectively. To overcome inertia in people with low levels of motivation to be vaccinated, appointments must be easily accessible.

scholarly journals Role of Superoxide Dismutases (SODs) in Hypertensive Rats After Administration of Mango Mistletoe Methanolic Extract

JSMARTech ◽  
2021 ◽  
Vol 2 (2) ◽  
pp. 061-064
Author(s):  
Mariyam Suroyya ◽  
◽  
Nour Athiroh Sjakoer ◽  
Nurul Mubarakati ◽  
◽  
...  
Keyword(s):  
Methanolic Extract ◽  
White Male ◽  
Male Rats ◽  
Control Group ◽  
Hypertensive Rats ◽  
Treatment Groups ◽  
Group A ◽  
The One ◽  
Endogenous Antioxidant ◽  
Post Hoc

Hypertension is a condition where there is an abnormal rise in blood pressure that may be the primary cause of cardiovascular disease. Hypertension induces the production of free radicals known as reactive oxygen species (ROS) and oxidative stress. The purpose of this study is to further examine the function of Dendropthoe pentandra as an endogenous antioxidant modulator in this case superoxide dismutase (SOD) in hypertensive rats.The testing approach used is experimental. Data were analyzed using the one-way ANOVA test and the Post Hoc test to see variations in SOD levels in different treatments. This research used a hypertensive rat model induced by deoxycorticosterone acetate (DOCA) and salt. The number of animals tested was 25 white male rats divided into 5 groups, each containing 5 rats.The group consisted of a control group, a group of non- Extract methanolic of mango mistletoe hypertensive rats, and three groups of hypertensive rats receiving mango mistletoe methanolic extract (EMBM) at dosages of 50 mg/kg, 100 mg/kg, and 200 mg/kg body weight. Based on the results of the study, it is known that the levels of increased lung SOD with extract methanolic of mango mistletoe dosage variations in all treatment groups were not different. The administration of mango parasite methanolic extract at a dose of 50 mg / kgBW was optimum in increasing lung SOD levels in hypertensive rats.

scholarly journals Vaccination, Immunity and Breakthrough: Quantitative Effects in Individual Immune Responses Illustrated by a Simple Kinetic Model

2021 ◽  
Vol 12 (1) ◽  
pp. 31
Author(s):  
Johann Michael Köhler
Keyword(s):  
Immune Reaction ◽  
Disease Risk ◽  
Herd Immunity ◽  
Kinetic Equations ◽  
Applied Model ◽  
Simple Kinetic Model ◽  
The One ◽  
The Individual ◽  
Stimulation Of ◽  
Infective Agent

The personal risks of infection, as well as the conditions for achieving herd immunity, are strongly dependent on an individual’s response to the infective agents on the one hand, and the individual’s reactions to vaccination on the other hand. The main goal of this work is to illustrate the importance of quantitative individual effects for disease risk in a simple way. The applied model was able to illustrate the quantitative effects, in the cases of different individual reactions, after exposition to viruses or bacteria and vaccines. The model was based on simple kinetic equations for stimulation of antibody production using different concentrations of the infective agent, vaccine and antibodies. It gave a qualitative explanation for the individual differences in breakthrough risks and different requirements concerning a second, third or further vaccinations, reconsidering different efficiencies of the stimulation of an immune reaction.

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