scholarly journals The Prevention of Hemorrhagic Stroke

2008 ◽  
Vol 14 (4) ◽  
pp. 365-373
Author(s):  
J. Raymond ◽  
JP Mohr ◽  

There is currently no evidence that preventive treatment of unruptured aneurysms or AVMs is beneficial and randomized trials have been proposed to address this clinical uncertainty. Participation in a trial may necessitate a shift of point of view compared to a certain habitual clinical mentality. A review of the ethical and rational principles governing the design and realization of a trial may help integrate clinical research into expert clinical practices. The treatment of unruptured aneurysms and AVMs remains controversial, and data from observational studies cannot provide a normative basis for clinical decisions. Prevention targets healthy individuals and hence has an obligation of results. There is no opposition between the search for objective facts using scientific methods and the ethics of medical practice since a good practice cannot forbid physicians the means to define what could be beneficial to patients. Perhaps the most difficult task is to recognize the uncertainty that is crucial to allow resorting to trial methodology. The reasoning that is used in research and analysis differs from the casuistic methods typical of clinical work, but clinical judgement remains the dominant factor that decides both who enters the trial and to whom the results of the trial will apply. Randomization is still perceived as a difficult and strange method to integrate into normal practice, but in the face of uncertainty it assures the best chances for the best outcome to each participant. Some tension exists between scientific methods and normal practice, but they need to coexist if we are to progress at the same time we care for patients.

2007 ◽  
Vol 13 (3) ◽  
pp. 225-237 ◽  
Author(s):  
J. Raymond ◽  
T. Nguyen ◽  
M. Chagnon ◽  
G. Gevry ◽  

In the absence of level one evidence, the treatment of unruptured intracranial aneurysms is grounded on opinions. Results of the largest registry available, ISUIA (the International Study on Unruptured Intraacranial Aneurysms) suggest that surgical or endovascular treatments are rarely justified. Yet the unruptured aneurysm is the most frequent indication for treatment in many endovascular centres. In preparation for the initiation of a randomized trial, we aimed at a better knowledge of endovascular expert opinions on unruptured aneurysms. We administered a standard questionnaire to 175 endovascular experts gathered at the WFITN meeting in Val d'Isère in 2007. Four paradigm unruptured aneurysms were used to poll opinions on risks of treatment or observation, as well as on their willingness to treat, observe or propose to the patient participation in a randomized trial, using six questions for each aneurysm. Opinions varied widely among lesions and among participants. Most participants (92.5%) were consistent, as they would offer treatment only if their estimate of the ten-year risk of spontaneous hemorrhage would exceed risks of treatment. Estimates of the natural history were consistently higher than that reported by ISUIA. Conversely, treatment risks were underestimated compared to those reported in ISUIA, but within the range reported in a recent French registry (ATENA). Participants were more confident in their evaluation of treatment risks and in their skills at treating aneurysms than in their estimates of risks of rupture entailed by the presence of the lesion, the latter being anchored at or close to 1% /year. The gulf between expert opinions, clinical practices and available data from registries persist. Expert opinions are compatible with the primary hypothesis of a recently initiated randomized trial on unruptured aneurysms (TEAM), which is a benefit of endovascular treatment of 4% compared to observation over ten years. Only data from a randomized trial could provide convincing objective evidence in favour or against preventive treatment of unruptured intracranial aneurysms.


2018 ◽  
Vol 13 (4) ◽  
pp. 97
Author(s):  
G. E. Bokov

The article is devoted to the study of the worldviews and social contradictions in Russian society on the example of two different positions on the relationship between religion and science. According to one of these positions these relationships are defined as conflict. The second, opposing point of view says there never was and there cannot be any conflict between religion and science. In the publication such points are called “the paradigm of conflict” and “the paradigm of dialogue”. It shows, the first “paradigm” in the Soviet period of Russian history was determined by ideologization of science and was an important part of anti-religious propaganda. On the contrary, “the paradigm of dialogue” has always been represented primarily by religious thinkers. Today it is the official position of the Russian Orthodox Church of the Moscow Patriarchate. The official Church document “The Basis of the Social Concept” says religion and science are designed to complement each other, especially in solving ethical problems that inevitably arise in the face of modern science. However, secular scientists often see in such statements the Church’s claims to active participation in the public life, including the educational process. Representatives of the academic community often speak out against the introduction of the theological educational programs and the theological departments in secular Universities of the Russian Federation. Thus, in contemporary Russian society some continue to believe that there is a conflict between religion and science, while others insist on the need for dialogue.


Author(s):  
Jennifer Knust

The pericope adulterae (John 7:53–8:11) is often interpreted as an inherently feminist story, one that validates women’s humanity in the face of a patriarchal order determined to reduce sexual sinners and women more generally to the status of object. Reading this story within a framework of queer narratology, however, leads to a different point of view, one that challenges the consequences of seeking rescue from a god and a text that are both quite willing to forge male homosocial bonds at a woman’s expense. As the history of this story also shows, texts and their meanings remain unsettled and therefore open to further unpredictable and contingent elaboration. Pondering my own feminist commitments, I attempt to imagine a world and a story where a woman is a person and Jesus is in need of rescue. Perhaps such a world is possible. Or perhaps it is not.


2021 ◽  
Vol 13 (7) ◽  
pp. 3965
Author(s):  
Robert Maršanic ◽  
Edna Mrnjavac ◽  
Drago Pupavac ◽  
Ljudevit Krpan

Since the Republic of Croatia is one of the most popular European and world tourist destinations, the aim of this paper is, from the user’s (n = 596) point of view, to research the importance of stationary traffic in tourist destinations. The purpose of this paper is to point out the possibilities of improving the tourist destination quality and sustainability through an adequate parking service. In order to corroborate constructed scientific hypotheses, a larger number of scientific methods were used from which a polling method, analysis and synthesis method, descriptive statistics method, t-test, and analysis of variance (ANOVA) should be singled out. The major finding of this paper indicates a relatively big importance of stationary traffic (M = 6.51; SD = 2.21) as an element of tourist destination quality. Moreover, regarding the quality of tourist destination, the results of this paper suggest that the parking space availability is more important than the way parking or parking payment are organized. Between the experienced parking problem in a tourist destination and age on one side and evaluation of the importance of stationary traffic as an element of tourist destination quality on the other side, a statistically important connection was established. Gained knowledge can be particularly helpful to hotel industry managers but also to traffic managers whose duty is to provide an adequate number of parking spaces in tourist destinations.


Author(s):  
V.B. Belov

The article examines the results of the last Bundestag elections. They marked the end of the Angela Merkel era and reflected the continuation of difficult party-political and socio-economic processes in the informal leader of the European Union. The main attention of the research focuses on the peculiarities of the election campaign of the leading parties and of the search for ways of further development of Germany in the face of urgent economic and political challenges. These challenges include the impact of the coronavirus crisis, the impact of the energy and digital transition to a climate-neutral economy, and the complex international situation. Based on original sources, the author analyzes the causes of the SPD victory and the CDU/CSU bloc defeat, the results of the negotiations of the Social Democrats with the Greens and Liberals, the content of the coalition agreement from the point of view of the prospects for the development of domestic and foreign policy and the economy of Russia's main partner in the west of the Eurasian continent. The conclusion is made about the absence of breakthrough ideas, the consistent continuation of the course started by the previous government for a carbon-free economy and the strengthening of the role of Germany in Europe and the world. For this course, conflicts and problems in achieving the set goals will be immanent due to the compromising nature of the coalition agreements.


Author(s):  
Artūrs Gaveika

Latvia has joined the Schengen area in 2007 and has already passed three Schengen evaluations. The aim of the article is to analyse the Schengen Borders Code in the context of border security.  Based on analysis of the Schengen Borders Code implementation in Latvia the author develops and puts forward suggestions on Schengen Borders Code content improvement as well as  its judicial systematisation development. The research tasks include the investigation of the current EU and national normative regulations, legal practices, the conclusions of Latvian and foreign law researchers by using analytical, historical and comparative methods.The improvement of the national normative regulation was started long before Latvia's accession to the Schengen area. In 2006, the Schengen Borders Code entered into force, which was revised due to the migration crisis in the Mediterranean region and adopted in 2016 in an improved version. The further development of the Schengen Borders Code is important from the point of view of the right to free movement of persons and from the point of view of ensuring public security in the face of today's challenges related to terrorism, international crime, uncontrolled migration and the spread of disease.The main achievement of the research is that the author has defined the main areas of Schengen Borders Code further development. 


2021 ◽  
pp. 163-184
Author(s):  
Richard Bartes

This contribution deals with the evolution of public finance in two selected European countries. France and Germany were selected as countries to compare their evolution of public finance. The reason why the two countries were chosen is their general proximity to each other in many respects. From a professional point of view, i.e. from the point of view of the discipline of public finance, however, these are countries with different concepts of public finance disciplines. The contribution presents the historical background, context and consequences of this evolution. The relevant public finance evolution is divided into several historical stages in each country. The contribution focuses on each stage separately and points out solutions and effect of each stage. The main aim of the contribution is to confirm or disprove the hypothesis that the evolution of the public finance discipline was different in each of the selected countries. The scientific methods used in the article are analysis and synthesis, description and comparative methods.


2015 ◽  
Author(s):  
Gina K Himes Boor ◽  
Paul Wade

The conservation and management of wild populations and ecosystems almost always involves making decisions in the face of uncertainty and risk. The application of science to the ecological decision-making process was something that the late Professor Daniel Goodman thought deeply about. In this paper we outline the three main principles that Dr. Goodman espoused for good practice when conducting analyses for ecological decision-making: 1) the results should be conditioned on all relevant data and information, 2) there must be a full characterization of all uncertainty, and it should be fully propagated into the result, and 3) doing so in the correct way will result in the calculation of an accurate probability distribution (conditioned on our understanding of the state of nature) that should be used directly for ecological decision-making. Dr. Goodman believed that in the context of threatened and endangered species management Population Viability Analysis (PVA), Bayesian statistics, and structured decision-making are the most logical tools to achieve the three principles. To illustrate the application of the principles and tools in a real management setting, we discuss a Bayesian PVA that Dr. Goodman produced for the endangered Steller sea lion. We conclude by discussing the practical and philosophical impediments that may limit the full realization of the three principles and we offer some suggested solutions.


Author(s):  
V. A. Nadein-Raevskiy

The article examines the process of formation of identity of Turkish President Recep Tayyip Erdogan – a charismatic leader, an adept of “moderate Islamism” one of the founders of the Justice and Development Party. Historically strong centralized authority was always normal for Turkey and the need for Turks in the charismatic leaders is evident even at the present time. Erdogan is stubborn and consistent, thanking to religious education in his family and in religious Lyceum Imam Hatib. He was always religious and since his student years, joined Islamic politicians. In his student years he became the head of the Istanbul Youth organization of the Islamist National Salvation Party, in whose ranks and files he received good practice of a political organizer. The crisis in the ranks of the Islamists after repeated bans of the Islamist party led to a split in its ranks and Erdogan and his associates established the Justice and Development Party (AKP). Creating the AKP, Erdogan and his colleagues received a very important support from the well-known Muslim preacher, writer and philosopher Fethullah Gülen living in Pennsylvania (USA). The political support of Gülen who has millions of followers in Turkey and a well-organized educational system of the “Hizmet” Movement operating not only in Turkey but also in 140 countries helped the AKP to win the elections to the Turkish Parliament. Numerous graduates of private schools, colleges and universities of F. Gülen has occupied leading positions in business, police, juridical structures and the armed forces of Turkey and became supporters of Erdogan. Economic reforms of the AKP has substantially strengthened the Turkish economy, increased the income of the population and managed to cope successfully with inflation. On this ground Erdogan’s credibility consequently grew in the face of voters who saw him a successful leader and skilled politician. However, Erdogan gradually returned to the daily life of Turks the Islamic religion, which caused discontent among the supporters of secular development of the country. Repeated attempts to remove the AKP from power were not successful. Using strong support from F. Gülen’s structures in the judiciary, Erdogan managed to organize high-profile lawsuits against the army leadership, politicians, and journalists – supporters of secular development of the country. In a popular referendum, the army was excluded from influence on the political system of the country. However, constant criticism of the policies of Erdogan from the side of F. Gülen led to the crisis of union between the two leaders. Using the failed coup attempt Erdogan accused in its organization Fethullah Gülen and began a wide crackdown against his supporters. 


2020 ◽  
Vol 3 (8) ◽  
pp. 100-112
Author(s):  
Artūrs Gaveika

Latvia joined the Schengen area in 2007 and has already passed three Schengen evaluations. The novelty of the article is aimed at analysis of Schengen Acquis implementation in Latvia and offer suggestions on its further implementation development. The aim of the study is to develop and propose suggestions on Schengen Acquis content improvement and its judicial systematisation development. The research tasks are to investigate the current EU and national normative regulations, legal practices, the conclusions of Latvian and foreign law researchers by using analytical, historical and comparative methods. The improvement of the national normative regulation was started long before Latvia's accession to the Schengen area. The further development of the Schengen acquis is important from the point of view of the right to free movement of persons and from the point of view of ensuring public security in the face of today's challenges related to terrorism, international crime, uncontrolled migration and the spread of disease. The main achievement of the research is that the author has defined the main areas of Schengen Acquis development.


Sign in / Sign up

Export Citation Format

Share Document