scholarly journals Pharmacological Role of Ostericum koreanum: A Short Viewpoint

2021 ◽  
Vol 16 (10) ◽  
pp. 1934578X2110507
Author(s):  
Narges Hosseini Nasab ◽  
Fahad Hassan Shah ◽  
Song Ja Kim
Keyword(s):  
Pharmacological Activity ◽  
Asian Countries ◽  
Pharmacological Activities ◽  
Respiratory Problems ◽  
Chinese Herbal ◽  
Anti Cancer ◽  
Ostericum Koreanum ◽  
Phytochemical Constituents ◽  
Rich Content

Ostericum koreanum Maxim., a perennial medicinal plant native to Asian countries, is traditionally exploited in Korean Oriental and Chinese Herbal Medicine. It has been used in the treatment of neuralgia, respiratory problems, and joint pain due to its rich content of phytochemicals. Therefore, the significant role of compounds present in O. koreanum should not be overlooked to explore and develop drugs against diseases. The purpose of this review is to provide a reference for researchers and to describe the phytochemical constituents and pharmacological activity of O. koreanum. In this mini review, we have collected the data from 1980 to 2020 regarding the phytochemicals present and pharmacological activities of this plant. Our findings indicated that this plant possesses a rich source of phytochemicals that have significant pharmacological activities, such as anti-microbial, anti-inflammatory, anti-pyretic, anti-influenza, anti-cancer, and neuroprotective. These phytochemicals have promising pharmacological activity which should be further explored for the treatment of various diseases.

scholarly journals A REVIEW ON PHARMACOLOGICAL ACTIVITY OF BENINCASA HISPIDA

2019 ◽  
Vol 7 (2) ◽  
Author(s):  
Neha Ayubkhan ◽  
Dr Mathew George ◽  
Dr Lincy Joseph ◽  
Dr K Sujith
Keyword(s):  
Mineral Elements ◽  
Diuretic Activity ◽  
Asian Countries ◽  
Vegetable Crop ◽  
Good Source ◽  
Pharmacological Activities ◽  
Benincasa Hispida ◽  
Pharmacological Studies ◽  
Medicinal Properties ◽  
Phytochemical Constituents

Benincasa hispida is a well-known plant and is cultivated throughout the plains of india and on the hills upto 1200 meter altitude. It is a popular vegetable crop widely used for nutritional and medicinal properties especially in asian countries. Benincasa hispida fruit has been valued as a nutritious vegetable as it provide a good source for natural sugars,organic acid, amino acid,vitamins and mineral elements. Phytochemical constituents of this plant are mannitol, triterpenoids, cucurbitin, β-sitosterin, flavanoids, glycosides, carotenes, vitamins and uronic acid. The pharmacological studies revealed that the plant exerted many pharmacological activities such as antiulcer, antihyperlipidemic, antihelmintic, antioxidant, neuropharmacological activity, diuretic activity. Keywords:  Benincasa hispida, antiulcer, diuretic, antihyperlipidemic, antihelminthic.

scholarly journals Pistacia integerrima (Shringi)- A Plant with Significant Pharmacological Activities

2021 ◽  
Vol 10 (5) ◽  
pp. 323-330
Author(s):  
Manish Grover ◽  
Keyword(s):  
Skin Diseases ◽  
Pharmacological Activities ◽  
North West ◽  
Alpha Pinene ◽  
Anti Cancer ◽  
The Family ◽  
The World ◽  
Anti Oxidant ◽  
Phytochemical Constituents ◽  
Important Medicinal Plant

Pistacia integerrima is an important medicinal plant belongs to the family Anacardiacea. It is commonly called as Crab’s claw in English and Shani/Shringi in Hindi. It is a single-stemmed, dioecious tree widely distributed in countries like Nepal, China, Afghanistan, Pakistan, Armenia, North-west and West Himalayas. The plant has significant applications in the traditional systems of medications such as Ayurveda, Unani and Siddha. In addition, the plant is also used in many folkloric cultures around the world to treat a vast array of human ailments such as diarrhoea, dysentery, fever, vomiting, skin diseases, respiratory ailments and psoriasis appetizer, hepatitis and liver related disorders. The characteristic feature of the plant is its essential oil content comprised of many important phytochemical constituents such as alpha-pinene, camphene, di-limonene, 1:8-cineol, caprylic acid, alpha-terpineol and aromadendrene. However, the plant contains many other important secondary metabolites such as steroids, flavonoids, tannins, saponins and phenols which are associated with important pharmacological activities such as anti-bacterial, anti-oxidant, anti-inflammatory, cardio-protective, anti-cancer, antidiarrhoeal, anticonvulsant and muscle relaxant. The aim of the present study is to summarize the recent pharmacological activities of Pistacia integerrima along with its utilization in traditional medication systems

scholarly journals Flavonoids from Nelumbo nucifera Gaertn., a Medicinal Plant: Uses in Traditional Medicine, Phytochemistry and Pharmacological Activities

Medicines ◽  
2018 ◽  
Vol 5 (4) ◽  
pp. 127 ◽  
Author(s):  
Duangjai Tungmunnithum ◽  
Darawan Pinthong ◽  
Christophe Hano
Keyword(s):  
Traditional Medicine ◽  
Nelumbo Nucifera ◽  
Asian Countries ◽  
Pharmacological Activities ◽  
Traditional Medicines ◽  
Taxonomic Description ◽  
Plant Uses ◽  
Anti Cancer ◽  
Phytochemical Compounds ◽  
Ancient Times

Nelumbo nucifera Gaertn. has been used as an important ingredient for traditional medicines since ancient times, especially in Asian countries. Nowadays, many new or unknown phytochemical compounds from N. nucifera are still being discovered. Most of the current research about pharmacological activity focus on nuciferine, many other alkaloids, phenolic compounds, etc. However, there is no current review emphasizing on flavonoids, which is one of the potent secondary metabolites of this species and its pharmacological activities. Therefore, following a taxonomic description, we aim to illustrate and update the diversity of flavonoid phytochemical compounds from N. nucifera, the comparative analysis of flavonoid compositions and contents in various organs. The uses of this species in traditional medicine and the main pharmacological activities such as antioxidant, anti-inflammatory, anti-diabetic, anti-obesity, anti-angiogenic and anti-cancer activities are also illustrated in this works.

Propitious Profile of Peppery Piperine

2020 ◽  
Vol 13 ◽  
Author(s):  
Harman Bakshi ◽  
Manju Nagpal ◽  
Manjinder Singh ◽  
Gitika Arora Dhingra ◽  
Geeta Aggarwal
Keyword(s):  
Pharmacological Activities ◽  
Drug Molecules ◽  
Anti Cancer ◽  
The Common ◽  
Toxic Potential ◽  
Receptor Targets ◽  
Therapeutic Activities ◽  
Potential Area ◽  
Therapeutic Profile

Background: Piperine is a key bioactive alkaloid found in plants of piperaceae family. The compound possesses various medicinal and pharmacological activities (cholesterol lowering, anti cancer, alzheimer’s disease etc). Owing to its various target receptors (TRPV1, P-gp, CYP3A4 etc.) and several mechanisms, piperine has been studied as bio-enhancer for other drugs and its role has been evidenced in literature. When administered with other drugs, it increases absorption of other drugs thereby reducing the dose and dose related toxic potential. There are various mechanisms of piperine as a bio-enhancer and the common ones are i) prevention of efflux of drug molecules out of the cells; ii) decreased metabolism of drugs thereby prolonging half-life of drugs resulting in reduced urinary excretion. The detailed mechanism indicating bio-enhancing role of piperine along with various target receptors have not been comprehensively summarised till date. Methods: Literature related to the molecular, enzymatic and receptor targets of piperine were studied and database was collected using various search engines such as j-gate, google scholar, scihub, pubmed, sciencedirect etc. The literature related to therapeutic activities of piperine and its bio-enhancer role for other drugs has been thoroughly studied and compiled in brief. Results: A detailed summary of piperine targets along with related mechanisms has been stated. A brief therapeutic profile of piperine alone has been produced with supporting literature. Piperine role as a potential bio-enhancer for other drugs has been summarized. Conclusion: Piperine is fascinating molecule of natural origin with several modes of its action, not only possess its own therapeutic activity but also enhances the therapeutic efficacy of other synthetic and natural drug molecules. Combination dosage forms of various API incorporating piperine as a bio-enhancer can be potential area of thrust for upcoming drug design and development.

scholarly journals Identification and Quantification, Metabolism and Pharmacokinetics, Pharmacological Activities, and Botanical Preparations of Protopine: A Review

Molecules ◽  
2021 ◽  
Vol 27 (1) ◽  
pp. 215
Author(s):  
Wangli Huang ◽  
Lingbo Kong ◽  
Yang Cao ◽  
Liang Yan
Keyword(s):  
Pharmacological Activity ◽  
Metabolic Pathways ◽  
Clinical Applications ◽  
Pharmacological Activities ◽  
Therapeutic Value ◽  
Pubmed Database ◽  
Wide Range ◽  
Anti Cancer ◽  
Identification And Quantification

Through pharmacological activity research, an increasing number of natural products and their derivatives are being recognized for their therapeutic value. In recent years, studies have been conducted on Corydalis yanhusuo W.T. Wang, a valuable medicinal herb listed in the Chinese Pharmacopoeia. Protopine, one of its components, has also become a research hotspot. To illustrate the identification, metabolism, and broad pharmacological activity of protopine and the botanical preparations containing it for further scientific studies and clinical applications, an in-depth and detailed review of protopine is required. We collected data on the identification and quantification, metabolism and pharmacokinetics, pharmacological activities, and botanical preparations of protopine from 1986 to 2021 from the PubMed database using “protopine” as a keyword. It has been shown that protopine as an active ingredient of many botanical preparations can be rapidly screened and quantified by a large number of methods (such as the LC-ESI-MS/MS and the TLC/GC-MS), and the possible metabolic pathways of protopine in vivo have been proposed. In addition, protopine possesses a wide range of pharmacological activities such as anti-inflammatory, anti-platelet aggregation, anti-cancer, analgesic, vasodilatory, anticholinesterase, anti-addictive, anticonvulsant, antipathogenic, antioxidant, hepatoprotective, neuroprotective, and cytotoxic and anti-proliferative activities. In this paper, the identification and quantification, metabolism and pharmacokinetics, pharmacological activities, and botanical preparations of protopine are reviewed in detail to lay a foundation for further scientific research and clinical applications of protopine.

scholarly journals Anti-Cancer Activity of Andrographolide: A Review

2021 ◽  
pp. 1-9
Author(s):  
Vishwanadham Yerragunta ◽  
Kavita Waghray ◽  
. Shivraj ◽  
N. J. P. Subhashini
Keyword(s):  
Biological Activities ◽  
Pharmacological Activities ◽  
Neuroprotective Effects ◽  
Cytotoxic Effects ◽  
Research Activities ◽  
Anti Cancer ◽  
Research Findings ◽  
Anti Oxidant ◽  
Anti Inflammation

Andrographolide, is a chemical compound obtained from the Andrographis paniculata (Family- Acanthaceae), maybe a diterpene lactone ring is responsible for various biological activities like anti-inflammation, anti-microbial anti-cancer, anti-obesity, anti-diabetes, anti-oxidant immunomodulatory, antiseptic, hypolipidemic, cardioprotective, hepatoprotective, neuroprotective effects and other biological activities. In Current research activities worldwide to exhibit the beneficial role of Andrographolide are continuously enriching the therapeutic arsenal of this important Phyto molecule. For this purpose, several databases were accustomed explore for the anticancer/cytotoxic effects of the andrographolide in pre-clinical and clinical studies. During this report, an attempt has been given to spotlight the research findings, related to therapeutic potentials and up-to-date development within the pharmacological activities of andrographolide. Andrographolide is often one of the potential agents within the treatment of cancer.

Pharmacognostical and pharmacological activity of Justicia gendarussa burm.f.: a comprehensive review

2020 ◽  
Vol 11 (3) ◽  
pp. 3384-3390
Author(s):  
Ashish ◽  
Anjali ◽  
Dixit Praveen K ◽  
Nagarajan K ◽  
Sahoo Jagannath
Keyword(s):  
Pharmacological Activity ◽  
Chemical Constituents ◽  
Biological Action ◽  
Andaman Islands ◽  
Comprehensive Review ◽  
Medicinal Value ◽  
Anti Oxidant ◽  
Phytochemical Constituents ◽  
Pharmacologically Active ◽  
Different Parts

Justicia gendarussa Burm .f. (family Acanthaceae) which is also known as willow-leaves and commonly known as Nili-Nirgundi, it is very commonly found nearby to China and its availability is very common in larger parts of India and Andaman islands. Traditionally it is used to treat various sorts of disorders such as wound healing, anti-inflammatory, anti-oxidant, antiproliferative, anti-arthritic etc. Justicia gendarussa is one of the crucial herbs which has been used in the Ayurveda. Majorly leaves parts of the plant shows the pharmacological activity but the root of the plant Justicia gendarussa is also have the important medicinal values. A large variety of pharmacologically active constituents i.e., alkaloids, flavonoids, saponin, carbohydrates, steroids, triterpenoids, carotenoids, aminoacids, tannins, phenolics, coumarines and anthaquinones are also present in this plant and they makes the plant pharmacologically important. The activity of the plant is also dependent on the solvent which is used for the extraction the various vital chemical constituents. The different- different parts of the plants having the different medicinal values also differ in the chemical values. This review is not only focused on the essential phytochemical constituents which is available in the plant but it also explains their necessary medicinal value to shows the essential biological action and phytopharmacological actions of various parts of the plant.

Resveratrol: A new potential therapeutic agent for melanoma?

2019 ◽  
Vol 26 ◽  
Author(s):  
Mohamad Hossein Pourhanifeh ◽  
Kazem Abbaszadeh-Goudarzi ◽  
Mohammad Goodarzi ◽  
Sara G.M. Piccirillo ◽  
Alimohammad Shafiee ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Therapeutic Agent ◽  
Current Knowledge ◽  
Treatment Resistance ◽  
Anti Cancer ◽  
Apoptosis Inducer ◽  
Life Threatening ◽  
First Time

: Melanoma is the most life-threatening and aggressive class of skin malignancies. The incidence of melanoma has steadily increased. Metastatic melanoma is greatly resistant to standard anti-melanomatreatments such as chemotherapy, and 5-year survival rate of cases with melanoma who have metastatic form of disease is less than 10%. The contributing role of apoptosis, angiogenesis and autophagy in the pathophysiology of melanoma has been previously demonstrated. Thus, it is extremely urgent to search for complementary therapeutic approachesthat couldenhance the quality of life of subjects and reduce treatment resistance and adverse effects. Resveratrol, known as a polyphenol component present in grapes and some plants, has anti-cancer properties due to its function as an apoptosis inducer in tumor cells, and anti-angiogenic agent to prevent metastasis. However, more clinical trials should be conducted to prove resveratrol efficacy. : Herein, for first time, we summarize current knowledge of anti-cancerous activities of resveratrol in melanoma.

Sign in / Sign up

Export Citation Format

Share Document