The associations between fasting blood glucose levels and mortality of SFTS in patients

Abstract Objective To identify the correlation between the level of at-admission fasting blood glucose (FBG) with poor outcomes in hospitalized patients suffering from severe fever with thrombocytopenia syndrome (SFTS). Methods Between April 1 and December 1, 2020, the list of hospitalized patients affected with SFTS infection was provided by the Infectious Disease Department at First Affiliated Hospital of Anhui Medical University, followed by the collection of information I.e., gender, age, diabetic history and the level of FBG on admission. Results In this study, a total of 77 patients were included and were categorized into three groups (< 5.6, 5.6–6.9, and ≥ 7.0 mmol/l) on the basis of their glucose level in the blood. The obtained results revealed that among three groups considerable variations were observed in leukocytes, FBG, D-Dimer, aspartate aminotransferase (AST), tumor necrosis factor-α (TNF-α), fibrin degradation products (FDP), and interleukin (IL)-10 level. Correlation analysis indicated a linear negative correlation between PLT and FBG (r = − 0.28, P = 0.01), however, a linear positive correlation was observed between AST, IL10, D-Dimer, and FDP levels and FBG (P-value < 0.05). Multivariate statistical analysis results shown that there was significant difference between group comparison (F = 17.01, P < 0.001) and interaction between group and time (F = 8.48, P < 0.05); but there was no significant difference between time point comparison (F = 0.04, P = 0.96). With the prolongation of time, the changes of FBG were different between survivor group and non-survivor group. The FBG in survival group shown a downward trend; The non-survivor group shown an upward trend. Conclusions Elevated level of FBG has been correlated with hypercoagulability, inflammation, and lower PLT in SFTS patients. The measurement of FBG level can help in evaluating the inflammatory process, hypercoagulability, and prognosis of patients suffering from SFTS. FBG can predict the prognosis of SFTS. It is necessary to pay attention to the role of FBG in the process of treatment in patients with SFTS.

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UJI AKTIVITAS ANTIDIABETES EKSTRAK ETANOL BUAH CABAI MERAH ( Capsicum annuum L. ) TERHADAP MENCIT PUTIH JANTAN

SCIENTIA : Jurnal Farmasi dan Kesehatan ◽

10.36434/scientia.v9i1.221 ◽

2019 ◽

Vol 9 (1) ◽

pp. 86 ◽

Cited By ~ 1

Author(s):

Zulkarni Zulkarni

Keyword(s):

Blood Glucose ◽

Capsicum Annuum ◽

Fasting Blood Glucose ◽

Ethanol Extract ◽

Negative Control ◽

Control Group ◽

Glucose Levels ◽

Capsicum Annuum L ◽

Blood Glucose Levels ◽

Significant Difference

This Research was conducted to determine the effect of ethanol extract from red chilli (Capsicum annuum L)in lowering blood glucose levels of hyperglycemic male white mices. This study used 30 malewhitemices and divided into 6 groups: negative control group, the positive control group, the treatmentgroup withdosage of 200 mg / kgweight, 400 mg / kgwieght, 600 mg / kg weight and a comparison group with glibenclamide with dosage of 5 mg / kgweightadministered orally for 21 days. The level of fasting blood glucose was checked 6 days after dexamethasone induced, and after the ethanol extract of red chilies on day 7th, 14th, and 21st. The data was analyzed statistically with one –way and two-way Anova by usingSPSS16 program and proceed with the test Duncan to look the significant difference between treatments. The results showed that the ethanol extract from red chilies with a dosage of 200mg / kgweight, 400mg / kgweight, 600 mg / kgweight showed the effect in lowering blood sugar levels in male white mices hyperglycemia significantly (p <0.05). The duration ethanol extract of red chili affected blood glucose levels. The most effective duration in lowering blood glucose levels is the administration of a preparation within 21 days.

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Red dragon fruit (Hylocereus spp.) peel marmalade effectively improve blood glucose and lipid profile of hypercholesterolemic wistar rats

JURNAL GIZI INDONESIA ◽

10.14710/jgi.9.1.61-67 ◽

2020 ◽

Vol 9 (1) ◽

pp. 61-67

Author(s):

Natalia Desy Putriningtyas ◽

Intan Permatasari ◽

Dita Oktaviani ◽

Anastasia Servia Raha ◽

Siti Wahyuningsih

Keyword(s):

Blood Glucose ◽

Functional Food ◽

Wistar Rats ◽

Fasting Blood Glucose ◽

Control Group ◽

Fruit Peel ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Dragon Fruit ◽

Significant Difference

Background: Polyphenols, antioxidants, dietary fiber, and vitamin contained in the red dragon fruit peel. Red dragon fruit peel can be processed into marmalade. Red dragon fruit peel marmalade has the potential to be a functional food. Functional food is food that has a physiological function based on scientific studies.Objectives: The objective of this study is to analyze the effect of red dragon fruit peel marmalade on fasting blood glucose levels, HDL, LDL, and triglycerides levels of hypercholesterolemic Wistar rats.Methods: This study used a pre-&post-test control group design. Hypercholesterolemic male Wistar rats were randomly assigned into five groups. Hypercholesterolemia was induced by 1% cholesterol powder and 0.5% cholic acid for two weeks. All groups received standard chow. Samples were grouped into five groups: K-; K+; K1 (0.94 g/kg b.wt/day); K2 (1.41 g/kg b.wt/day); K3 (1.88 g/kg b.wt/day). The intervention was carried out for 28 days. GDP level was measured using the GOD-PAP. HDL, LDL, and triglyceride were analyzed with spectrophotometry. GDP, HDL, LDL, and triglyceride levels were measured twice before fasting. A paired t-test and one-way ANOVA were used to analyze the data.Results: The result showed that K-; K1; K2; K3 had a significant difference between groups before and after the intervention (p<0.05). Red dragon fruit peel Marmalade was able to reduce the levels of GDP, LDL, triglycerides, and increase HDL (p <0.05).Conclusion: Red dragon fruit peel marmalade reduced fasting blood glucose levels, LDL, triglyceride levels, and increased HDL levels of hypercholesterolemic Wistar rats.

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Blood Glucose Levels on Beagle (Canis familiaris) in Kenagarian Mungo, Luak District Lima Puluh Kota West Sumatra

Jurnal Medika Veterinaria ◽

10.21157/j.med.vet..v9i2.3489 ◽

2015 ◽

Vol 9 (2) ◽

Author(s):

Afrio Arisman ◽

Sugito Sugito ◽

Zuhrawati Zuhrawati ◽

M. Hasan ◽

Abdul Harris ◽

...

Keyword(s):

Blood Glucose ◽

Fasting Blood Glucose ◽

Test Results ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Significant Difference ◽

West Sumatra ◽

The Difference ◽

Hunting Frequency ◽

Mean Glucose

This research aimed to determine glucose levels of beagle which is maintained by Sports Association of Pig Hunting (PORBI) in Kenagarian Mungo Sub-district Luak District Lima Puluh Kota, West Sumatra. Blood samples were collected from 20 beagles. Blood sampling was performed during fasting time and two hours postprandial. Data were analyzed with analysis of Chisquare (x2). The results showed that mean glucose level in the fasting state beagle was 63.45±11.84 mg /dl and two hours postprandial was 93.45±12.52 mg/dl. The test results showed statistically significant differences (P<0.05) postprandial, hunting frequency and multivitamin injection on blood glucose levels. The test results showed no statistically significant difference (P>0.05) between the frequency of feeding and supplementary feeding on blood glucose levels. Conclusion average blood glucose levels beagle still in the normal range. There is a difference in blood glucose between two hours postprandial with a fasting blood glucose levels and the difference between the hunting frequency and giving multivitamins injection on blood glucose levels and there was no difference on blood glucose levels between the frequency feeding, and supplemental feeding.Key words: beagle, glucose levels, hunting, multivitamins

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Comparison of Frequency Distribution of Diabetes in Hepatitis B and C Patients and Other People in Birjand

Modern Care Journal ◽

10.5812/modernc.111024 ◽

2021 ◽

Vol 18 (1) ◽

Author(s):

Masood Ziaee ◽

Mahboube Saljoughi ◽

Forough Fardinfar ◽

Farah Madarshahian ◽

Azadeh Ebrahimzadeh

Keyword(s):

Blood Glucose ◽

Hepatitis C ◽

Hepatitis B ◽

Frequency Distribution ◽

Statistical Tests ◽

Fasting Blood Glucose ◽

Diabetic Patients ◽

Retrospective Case ◽

Glucose Levels ◽

Significant Difference

Background: Diabetes and hepatitis are among the most common diseases in the world. Hepatitis C virus leads to extra-liver manifestations, including endocrine disease and diabetes. The prevalence of hepatitis C and B in diabetic patients and the prevalence of diabetes in hepatitis C and B patients are higher than those in normal populations, and if each is added to the other, the complications will be more and the consequences will be worse. Objectives: This study aimed to compare the frequency distribution of diabetes and serum lipid levels in hepatitis B and C patients and other people. Methods: In this retrospective case-control study, 80 patients with hepatitis B and C and 160 patients without hepatitis were included. In both groups, those with two glucose levels above 126 mg/dL were considered as diabetic subjects. Also, the tests for factors such as cholesterol, TG, LDL, HbA1c, HDL, and liver ultrasonography were performed for patients. Data were collected and entered into SPSS 23 software and analyzed using descriptive statistical tests (t test and chi-square or Fisher's exact test) at a significance level of α = 0.05. Results: A total of 240 patients [80 cases (hepatitis B or C positive) and 160 controls] were enrolled. Of them, 46.3% were females and most of them were in the age range of 45-55 years. Besides, 14 (5.8%) subjects had high fasting blood glucose levels of more than 126 mg/dl twice, and were considered to have diabetes. Among them, four (5.0%) cases (all having hepatitis B) and 10 (6.3%) controls were diabetics. Statistical analysis showed no significant difference in the mean serum lipids of cholesterol and LDL between the case and control groups (P < 0.1) but there was a significant association between HDL and TG in both groups (P = 0.02). Conclusions: All patients with hepatitis B and C should be screened for diabetes, and in addition to fasting blood glucose, we suggest that HbA1c be measured to confirm or rule out diabetes.

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Pengaruh lama mengunyah terhadap kadar glukosa postprandial dewasa obesitas

JURNAL GIZI INDONESIA ◽

10.14710/jgi.8.1.24-30 ◽

2020 ◽

Vol 8 (1) ◽

pp. 24

Author(s):

Arin Wulansari ◽

Fryta Ameilia Luthfinnisa ◽

Fuadah Uyun ◽

Dwi Retnoningrum ◽

Fifin Luthfia Rahmi ◽

...

Keyword(s):

Blood Glucose ◽

Fasting Blood Glucose ◽

Postprandial Glucose ◽

Postprandial Blood Glucose ◽

Glucose Levels ◽

Glucose Testing ◽

Blood Glucose Levels ◽

Cephalic Phase ◽

Significant Difference ◽

The Mean

Background: Obesity cause various physiological changes in the body, one of which is insulin resistance causes high blood glucose levels. Chewing is a stimulus of cephalic phase responses and sensory stimulation that can increase hormones releasing such as insulin, ghrelin, cholecystokinin (CCK) and glucagon like peptide-1 (GLP-1). Chewing plays important role in determining postprandial plasma glucose concentration.Objective: Investigate the effect of chewing on postprandial blood glucose in obese adults.Method: This was true experimental research. Research subjects were treated in the form of chewing 22 times and 40 times each mouthful. Blood glucose levels were measured using glucometer on fasting blood glucose and postprandial blood glucose 15 minutes, 30 minutes, 60 minutes, and 120 minutes. Statistical test using Independent t-test.Results: The mean postprandial glucose levels in the 22 chews group at 15 minutes, 30 minutes, 60 minutes, and 120 minutes were 112.11 ± 14.3328, 126.11 ± 15.667, 116.94 ± 15.539, and 89.67 ± 11.668 . While the mean postprandial blood glucose levels in the 40 chews group at 15 minutes, 30 minutes, 60 minutes, and 120 minutes were 122.22 ± 14.381, 129.61 ± 15.112, 109.50 ± 14.995, and 85.83 ± 13.963. There were statistically significant differences between chewing groups 22 times and chewing 40 times on fasting blood glucose and 15 minutes postprandial blood glucose (p = 0.041 and p = 0.042), while on 30 minutes postprandial glucose testing, 60 minutes , and 120 minutes there was no significant difference (p> 0.05).Conclusion: There was significant differences in 15 minutes postprandial blood glucose level between group 22 times chewing and 40 times chewing each mouthful.

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Pengaruh pemberian susu almond terhadap glukosa darah puasa pada tikus diabetes

JURNAL GIZI INDONESIA ◽

10.14710/jgi.7.2.86-91 ◽

2019 ◽

Vol 7 (2) ◽

pp. 86-91

Author(s):

Ryta Ristantia Ningsih ◽

Enny Probosari ◽

Binar Panunggal

Keyword(s):

Blood Glucose ◽

Treatment Group ◽

Metabolic Diseases ◽

Fasting Blood Glucose ◽

Glucose Measurement ◽

Control Group ◽

Control Group Design ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Significant Difference

Background: Type 2 Diabetes Mellitus is a group of metabolic diseases with characteristic hyperglycemia that occurs due to abnormalities in insulin secretion and insulin action. Diet plus high fiber can help control glucose levels. Almond contains fiber, vitamin E, and magnesium that contributes to the fasting blood glucose levels. This study aimed to analyze the effect of almond milk to the fasting blood glucose diabetic rats.Method: This study used an experimental design with pre-post test control group design. The sample were Rattus norvegicus Wistar which were divided into 4 groups: K (-), K (+), A1 and A2. Almond milk was given in the group treatmeant for 14 days with a dose of 4.32 ml and 8.64 ml. Fasting blood glucose measurement taken before and after treatment used Oxidase Glucose - Peroxidase Aminoantypirin (GOD PAP). Analysis of data used paired t-test, ANOVA and Post Hoc.Results: The fasting blood glucose levels decreased significantly (p = 0.01) in the treatment group which were intervened with almond milk. A decrease in fasting blood glucose levels in a dose treatment group 1 for 116.96 ± 4.45 (p = 0:01), whereas in the group treated at a dose of 2 for 155.53 ± 3.15 (p = 0.01). There were a significant difference in decreased of the fasting blood glucose levels between the two treatment groups (p = 0.01).Conclusion: Giving a dose almond milk 4.32 ml and 8.64 ml for 14 days can lower the fasting blood glucose levels significantly.

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Fasting blood glucose and newborn birth weight of non- diabetic Sudanese women

F1000Research ◽

10.12688/f1000research.8416.1 ◽

2016 ◽

Vol 5 ◽

pp. 641

Author(s):

Abdelmageed Elmugabil ◽

Duria A. Rayis ◽

Ishag Adam ◽

Mohamed F. Lutfi

Keyword(s):

Regression Analysis ◽

Blood Glucose ◽

Birth Weight ◽

Linear Regression ◽

Linear Regression Analysis ◽

Fasting Blood Glucose ◽

Sociodemographic Characteristics ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Significant Difference

Background Although risk factors for abnormal birth weight has been extensively investigated, whether the physiological range of glucose tolerance affects birth weight in non-diabetic mothers needs to be verified by further research. Objectives To assess the effect of maternal sociodemographic characteristics, obstetric and anthropometric measurements, fasting and 2-hour blood glucose levels on birth weight. Methods One hundred and thirty four women were followed from early pregnancy until delivery at Saad Abualila Hospital, Khartoum, Sudan. Fasting and 2-hour glucose levels following administration of 75 g oral glucose was performed in the third trimester. Association between birth weight and maternal sociodemographic characteristics, obstetric and anthropometric measurements, haemoglobin, fasting and 2-hour blood glucose levels were assessed by linear regression analysis. Results The mean (SD) birth weight was 3127.7 (480.0) g, while the 10th and 90th centile were 2500 and 3800 g, respectively. There was no significant difference in the birth weight between male (n=73) and female (n=61) newborns [3167.8 (545.0) vs 3068.9 (384.0) g, P= 0.196]. Likewise there was no significant difference in the birth weight of newborns born to primipara and multipara mothers [3101.7 (529.0) g vs 3151.4 (432.0) g, P= 0.551]. Linear regression analysis demonstrated significant association between fasting blood glucose and birth weight (20 g, P = 0.028). None of the other maternal/fetal characteristics was associated with birth weight, including maternal age, body mass index, gravidity, weight gain during pregnancy, interpregnancy interval, history of miscarriage, haemoglobin level, blood pressure, fetal gender and gestational age. Conclusion In this study fasting blood glucose was found to be predictor of birth weight among neonates of non-diabetic Sudanese mothers.

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The Associations Between Fasting Plasma Glucose Levels and Mortality of SFTS in Patients

10.21203/rs.3.rs-228628/v1 ◽

2021 ◽

Author(s):

Yin Zhang ◽

Yu Zhang ◽

Yuanhong Xu ◽

Ying Huang

Keyword(s):

Plasma Glucose ◽

Fasting Plasma Glucose ◽

Degradation Products ◽

Hospitalized Patients ◽

P Value ◽

Glucose Levels ◽

Fasting Plasma ◽

Poor Outcomes ◽

Factor Α ◽

D Dimer

Abstract Objective To identify the correlation between the level of at-admission fasting plasma glucose (FPG) with poor outcomes in hospitalized patients suffering from severe fever with thrombocytopenia syndrome (SFTS). Methods Between April 1 and December 1, 2020, the list of hospitalized patients affected with SFTS infection was provided by the Infectious Disease Department at First Affiliated Hospital of Anhui Medical University, followed by the collection of information I.e., gender, age, diabetic history and the level of FPG on admission. Results In this study, a total of 77 patients were included and were categorized into three groups (<5.6, 5.6–6.9, and ≥7.0 mmol/l) on the basis of their glucose level in the blood. The obtained results revealed that among three groups considerable variations were observed in leukocytes, FPG, D-Dimer, aspartate aminotransferase (AST), tumor necrosis factor-α (TNF-α), fibrin degradation products (FDP), and interleukin (IL)-10 level. Correlation analysis indicated a linear negative correlation between PLT and FPG (r = −0.28, P = 0.01), however, a linear positive correlation was observed between AST, IL10, D-Dimer, and FDP levels and FPG (P-value < 0.05). Conclusions Elevated level of FPG has been correlated with hypercoagulability, inflammation, and lower PLT in SFTS patients. The measurement of FPG level can help in evaluating the inflammatory process, hypercoagulability, and prognosis of patients suffering from SFTS.

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TEST OF THE EFFECTIVENESS ANTIHIPERGLIKEMIA OF COMBINATION CUCUMBER JUICE(Cucumis sativus) AND TOMATO (Solanum lycopersicum L) ON THE WISTAR MALE RAT

JURNAL BORNEO AKCAYA ◽

10.51266/borneoakcaya.v4i1.76 ◽

2017 ◽

Vol 4 (1) ◽

pp. 16-23

Author(s):

Suntoro ◽

Ressi Susanti ◽

Robiyanto

Keyword(s):

Blood Glucose ◽

Fasting Blood Glucose ◽

Tomato Juice ◽

Male Rat ◽

Control Group ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Significant Difference ◽

Decrease Blood Glucose ◽

Tolerance Method

Diabetes mellitus is a metabolic disease with characteristics of hyperglycemia. Conventional treatments using oral medications such as glibenclamide and metformin have many side effects. Therefore, it is necessary to find an alternative drug that is more effective and safer. Some agents that are often used as anantihiperglikemia are cucumber and tomato.The purpose of this study was to determine the effectiveness of combination of cucumber and tomato juice to decrease blood glucose levels of male Wistar ratsusingglucose tolerance method. Male Wistar rats were fasted for 10 hours and then measured the levels of fasting blood glucose. Then animals test were given the juice (single and combination), 30 minutes later were given a dose of sucrose load of 6.75 g / KgBW orally. Blood glucose levels of animal testre-measured at 30th, 60th, 90th, and 120th minutes after loading sucrose using a glucometer.The measurement results showed that blood glucose levels of the combination of cucumber and tomato juice group with dose ratio of 28 g/KgBW:16.8 g/KgBW gave decrease blood glucose levels significantly compared to the negative control group (p≤0.05) and didn’t not provide a significant difference compared to the metformin group (p ≥0.05).

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PERBANDINGAN PROFIL GLUKOSA DARAH PASIEN STROKE ISKEMIK DAN STROKE HEMORAGIK DI RSUP FATMAWATI TAHUN 2018

Jurnal Muara Sains, Teknologi, Kedokteran dan Ilmu Kesehatan ◽

10.24912/jmstkik.v5i1.8217 ◽

2021 ◽

Vol 5 (1) ◽

pp. 75

Author(s):

Intan Rahma Husna ◽

Riezky Valentina Astari ◽

Tuty Rizkianti

Keyword(s):

Ischemic Stroke ◽

Blood Glucose ◽

Glucose Level ◽

Hemorrhagic Stroke ◽

Fasting Blood Glucose ◽

Random Blood Glucose ◽

Glucose Levels ◽

Consecutive Sampling ◽

Blood Glucose Levels ◽

Significant Difference

Stroke is the death of brain cells due to lack of blood flow and oxygen to the brain by blockage or rupture of an artery. Stress hyperglycemia in acute stroke may worsen the clinical outcome and the prognosis of stroke. The purpose of this study is to find out and compare blood glucose profile between ischemic stroke and hemorrhagic stroke. This is an observational analytic cross-sectional research using consecutive sampling. Data was obtained through medical record from January to December 2018 in RSUP Fatmawati with each group of stroke consisting of 74 samples. Data was processed using SPSS 2017. Mann-Whitney test shows a significant difference in random blood glucose levels between ischemic stroke and hemorrhagic stroke (p = 0.024), with the median value of random blood glucose level during ischemic stroke is 115.50 mg / dL and hemorrhagic stroke is 136.50 mg / dL. The results also shows a significant difference in fasting blood glucose levels between ischemic stroke and hemorrhagic stroke (p = 0.042), with the median value of fasting blood glucose level for ischemic stroke is 116.50 mg / dL and hemorrhagic stroke is 125.50 mg / dL. A significant difference is also seen in 2 hours post-prandial glucose level between ischemic stroke and hemorrhagic stroke (p = 0.028), with the median value of 2 hours post-prandial glucose level of ischemic stroke is 130 mg / dL and hemorrhagic stroke is 147.50 mg / dL. Keywords: Ischemic Stroke; Hemorrhagic Stroke; Random Blood Glucose; Fasting Blood Glucose; 2 Hour Post-Prandial Blood Glucose AbstrakStroke adalah kematian sel-sel otak akibat hilangnya pasokan darah dan oksigen ke otak karena adanya hambatan atau ruptur arteri yang menuju otak. Pada stroke fase akut dapat terjadi hiperglikemia reaktif yang dapat memperburuk keluaran klinis dan prognosis stroke. Penelitian ini dilakukan untuk mengetahui dan membandingkan profil glukosa darah antara stroke iskemik dan stroke hemoragik. Penelitian ini bersifat analitik observasional dengan desain potong lintang dan pemilihan sampel consecutive sampling. Data didapat dari rekam medis periode Januari-Desember 2018 di RSUP Fatmawati dengan masing-masing kelompok stroke sebanyak 74 sampel. Pengolahan data dilakukan dengan program SPSS tahun 2017. Uji Mann-Whitney menunjukkan adanya perbedaan bermakna kadar Glukosa Darah Sewaktu antara stroke iskemik dengan stroke hemoragik (p = 0,024), dengan nilai median Glukosa Darah Sewaktu stroke iskemik adalah 115,50 mg/dL dan stroke hemoragik adalah 136,50 mg/dL. Hasil juga menunjukkan adanya perbedaan bermakna kadar Glukosa Darah Puasa antara stroke iskemik dan stroke hemoragik (p = 0,042), dengan nilai median Glukosa Darah Puasa stroke iskemik adalah 116,50 mg/dL dan stroke hemoragik adalah 125,50 mg/dL, serta adanya perbedaan bermakna kadar Glukosa Darah 2 Jam Post-Prandial antara stroke iskemik dan stroke hemoragik (p = 0,028), dengan nilai median Glukosa Darah 2 Jam Post-Prandial stroke iskemik adalah 130 mg/dL dan stroke hemoragik adalah 147,50 mg/dL.

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