scholarly journals Gut microbiota modulation as a possible mediating mechanism for fasting-induced alleviation of metabolic complications: a systematic review

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Pooneh Angoorani ◽  
Hanieh-Sadat Ejtahed ◽  
Shirin Hasani-Ranjbar ◽  
Seyed Davar Siadat ◽  
Ahmad Reza Soroush ◽  
...  
Keyword(s):  
Systematic Review ◽  
Gut Microbiota ◽  
Web Of Science ◽  
Intermittent Fasting ◽  
Meal Frequency ◽  
Beneficial Bacteria ◽  
Metabolic Complications ◽  
Ramadan Fasting ◽  
Positive Effects ◽  
Alternate Day Fasting

Abstract Background Intermittent fasting has been reported to have positive effects on obesity, diabetes, cardiovascular diseases, hypertension, and several neurodegenerative diseases through different mechanisms such as alteration in the gut microbiota. This systematic review was conducted with the aim of providing an overview of the existing animal and human literature regarding the gut microbiota alterations in various fasting regimens. Method A systematic literature search was conducted on PubMed, Scopus and Web of Science databases up to May 2021 to find all relevant studies examining the gut microbiota alteration during the fasting. Original researches on animal models or human patients were included in this study. Results The search fulfilled 3072 documents from which 31 studies (20 animal and 11 human studies) were included. Upon fasting, abundance of several beneficial bacteria including Lactobacillus and Bifidobacterium shifted significantly. Moreover, some taxa, including Odoribacter which negatively associated with blood pressure bloomed during fasting. Ramadan fasting, as a kind of intermittent fasting, improves health parameters through positive changes in gut microbiota including upregulation of A. muciniphila, B. fragilis, Bacteroides and butyric acid–producing Lachnospiraceae. Conclusion The findings suggest that different fasting regimens including alternate-day fasting, calorie- and time-restricted fasting programs and Ramadan fasting could promote health maybe through the modulation of gut microbiome. However, further studies are needed to explore properly the connection between gut microbiota and meal frequency and timing.

scholarly journals The effect of calorie intake, fasting, and dietary composition on metabolic health and gut microbiota in mice

BMC Biology ◽  
2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Ziyi Zhang ◽  
Xiaoyu Chen ◽  
Yuh Jiun Loh ◽  
Xin Yang ◽  
Chenhong Zhang
Keyword(s):  
Gut Microbiota ◽  
High Fat Diet ◽  
Metabolic Health ◽  
Metabolic Phenotype ◽  
Intermittent Fasting ◽  
High Fat ◽  
Eating Pattern ◽  
Positive Effects ◽  
Normal Chow ◽  
Ad Libitum

Abstract Background Calorie restriction (CR) and intermittent fasting (IF) can promote metabolic health through a process that is partially mediated by gut microbiota modulation. To compare the effects of CR and IF with different dietary structures on metabolic health and the gut microbiota, we performed an experiment in which mice were subjected to a CR or IF regimen and an additional IF control (IFCtrl) group whose total energy intake was not different from that of the CR group was included. Each regimen was included for normal chow and high-fat diet. Results We showed that in normal-chow mice, the IFCtrl regimen had similar positive effects on glucose and lipid metabolism as the CR regimen, but the IF regimen showed almost no influence compared to the outcomes observed in the ad libitum group. IF also resulted in improvements, but the effects were less marked than those associate with CR and IFCtrl when the mice were fed a high-fat diet. Moreover, CR created a stable and unique gut microbial community, while the gut microbiota shaped by IF exhibited dynamic changes in fasting-refeeding cycles. At the end of each cycle, the gut microbiota of the IFCtrl mice was similar to that of the CR mice, and the gut microbiota of the IF mice was similar to that of the ad libitum group. When the abundance of Lactobacillus murinus OTU2 was high, the corresponding metabolic phenotype was improved regardless of eating pattern and dietary structure, which might be one of the key bacterial groups in the gut microbiota that is positively correlated with metabolic amelioration. Conclusion There are interactions among the amount of food intake, the diet structure, and the fasting time on metabolic health. The structure and composition of gut microbiota modified by dietary regimens might contribute to the beneficial effects on the host metabolism.

scholarly journals Deconstructing AMO framework: a systematic review

2016 ◽  
Vol 12 (4) ◽  
pp. 1040 ◽  
Author(s):  
Juan A. Marin-Garcia ◽  
Juan Martinez Tomas
Keyword(s):  
Social Sciences ◽  
Systematic Review ◽  
Web Of Science ◽  
Social Sciences And Humanities ◽  
Positive Effects ◽  
Scientific Papers ◽  
And Performance ◽  
The Relationship ◽  
Measures Of Performance ◽  
Shed Light

Purpose: The AMO framework has been widely accepted in HRM literature for explaining the linkage between human resources practices and performance. However, it remains unclear whether this model has been fully demonstrated or not. Hence, we propose a systematic review that aims at identifying those investigations that have thoroughly tested the model, as well as the approaches used by them.Design/methodology/approach: Systematic literature review, filtering scientific papers published in journals indexed in Scopus, Web of Science or Google Scholar, from the year 1993 to 2016, in the field of Social Sciences and Humanities with research that indirectly apply the AMO model in their analysis.Findings: AMO model is an excellent and structured framework that provides a better understanding of the relationship between HRM and performance. Moreover, the effectiveness of the model's proposal appears to be beyond doubt. In fact, a well trained and skilled employee will perform better, and a motivated worker will be ready to "go the extra mile". Likewise, if the work environment does not provide adequate opportunities, both abilities and motivation might become meaningless. However, we consider that many other factors could influence the positive effects of HPWS. As a matter of fact, not only contextual factors, but also individual beliefs, personal affinities, or personal circumstances (among others) might affect the implementation of these practices and the subsequent outcomes. For this reason, we consider that developing an HRM model that perfectly fit any situation is a very complicated, if not impossible, task.Research limitations/implications: The results show a significant variability in both research approaches and variables taken into consideration. In addition, it seems that little research has been conducted to verify the AMO model directly. Therefore, we consider that there is a great need to study the model from a more systematic perspective. A thorough understanding of the model could lead to a better understanding of the problems that organizations face when implementing human resource practices.Originality/value: Our study shed light on some aspects of the AMO framework within the HRM context. Specifically, we aimed to identify whether or not it is possible to confirm the model as it was originally proposed. We also find out which HR practices and measures of performance were considered across investigations, to define a standard approach.

scholarly journals The Relationship between Music and Food Intake: A Systematic Review and Meta-Analysis

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2571
Author(s):  
Tianxiang Cui ◽  
Jiaxuan Xi ◽  
Chanyuan Tang ◽  
Jianwen Song ◽  
Jinbo He ◽  
...  
Keyword(s):  
Systematic Review ◽  
Food Intake ◽  
Effect Size ◽  
Web Of Science ◽  
Meta Analysis ◽  
Experimental Studies ◽  
Inclusion Criteria ◽  
Positive Effects ◽  
Small Effect Size ◽  
The Relationship

Food intake has been shown to be related to several environmental factors including the presence of music. However, previous findings of the relationship between music and food intake are inconsistent. In the present study, a systematic review and meta-analysis was conducted to quantitatively review the extent to which music is associated with food intake as well as to investigate potential moderators that might have contributed to the heterogeneity of the existing findings. Literature was searched on four databases (i.e., PsycINFO, Web of Science, PubMed, and ProQuest Dissertations and Theses) and Google Scholar. Nine articles published from 1989 to 2020 met our inclusion criteria. A meta-analysis was carried out via a three-level random-effects model. The overall effect size (i.e., Hedges’ g) was 0.19 (95% Confidence Interval: −0.003, 0.386; SE = 0.10, t = 1.99, p = 0.054), indicating a marginally significant but small effect size. Body Mass Index (F(1, 21) = 5.11, p = 0.035) was found to significantly contribute to the heterogeneity of effect sizes, with larger positive effects of music on food intake for individuals with higher BMI. However, music-related features did not significantly moderate the relationship between music and food intake. More experimental studies are needed to update the current meta-analysis and get a better understanding of this topic.

scholarly journals Intermittent fasting - a potential approach to modulate the gut microbiota in humans? A systematic review

2021 ◽  
pp. 1-8
Author(s):  
Kate Llewellyn-Waters ◽  
Mohammad M. Abdullah
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Gut Microbiota ◽  
Dietary Habits ◽  
Intermittent Fasting ◽  
Gut Health ◽  
Medline Search ◽  
Beneficial Effects ◽  
The Rich ◽  
The Impact

Research on gut microbiota has increased in popularity over the past decade, with evidence associating different dietary habits with changes in the makeup of the rich ecosystem of microorganisms that performs a variety of functions and induces a range of health effects, within and well beyond the gastrointestinal tract. Similarly, intermittent fasting (IF), an umbrella term describing various regimens of periods of voluntary abstinence from food and drink, has classically been associated with favourable impacts on cardiovascular risk factors, body weight, circadian biology, and, more recently, the gut health..The objective of this PRISMA systematic review was to summarize the peer-reviewed literature of clinical trials related to the impact of IF regimens on the gut microbiota. A MEDLINE search was conducted using PubMed and the keywords “intermittent fasting”, “gut microbiota”, “microbes”, and others. Whilst the field is still in its infancy, an emerging body of evidence suggests beneficial effects of IF on the health of the gut through increasing the microbial diversity and abundance, with possible clinical implications related to improving the immune function and ameliorating the metabolic status. Further research in larger clinical trials is warranted before practical recommendations for the public health can be made.

scholarly journals Efectos del entrenamiento de fuerza y suplementación en personas vegetarianas: Revisión sistemática (Effects of strength training and supplementation in vegetarian people: Systematic review)

Retos ◽  
2018 ◽  
pp. 247-251
Author(s):  
Jose Antonio Rodríguez-Gandullo ◽  
Francisco Álvarez-Barbosa
Keyword(s):  
Systematic Review ◽  
Strength Training ◽  
Web Of Science ◽  
Creatine Supplementation ◽  
Vegetarian Diet ◽  
Positive Effects ◽  
Revisión Sistemática ◽  
Prisma Statement ◽  
Total Creatine

El objetivo del estudio fue investigar los efectos de un entrenamiento de fuerza más una suplementación adicional sobre deportistas adultos no profesionales y vegetarianos. Una revisión sistemática de las bases de datos MEDLINE (PubMed), Scopus, SportDiscus y WOS (Web of Science) fue realizada siguiendo el modelo PICO, utilizando términos que representasen a personas vegetarianas de entre 18 y 64 años que hubiesen realizado una intervención basada en un entrenamiento de fuerza más suplementación. Siguiendo el procedimiento PRISMA, de los 62 estudios encontrados tan solo 3 cumplieron todos los criterios por lo que fueron analizados en su totalidad para poder ser incluidos en la revisión. La calidad metodológica de los estudios se evaluó mediante la escala PEDro. El estudio de Shomrat et al. (2000) la suplementación con creatina provocó un incremento de la masa corporal y potencia media. El estudio de Burke et al. (2003) obtuvo con la suplementación de creatina incrementos en la fosfocreatina (PCr), creatina total (TCr), fuerza, fibras musculares de tipo II y tejido magro, siendo estos cambios más significativos en las personas vegetarianas. Por último, en el estudio de Burke et al. (2008), el factor de crecimiento insulínico de tipo 1 (IGF-1) se incrementó en un 67%, con mayor acumulación en el grupo que fue suplementado con creatina. A raíz de estos resultados se puede concluir que la suplementación con creatina puede provocar efectos positivos en el rendimiento de los deportistas vegetarianos, ya que puede cubrir ciertas carencias derivadas de la dieta vegetariana.Abstract: The aim of the study was to investigate the effects of strength training plus additional supplementation on non-professional adult athletes who are vegetarian. A systematic review of MEDLINE (PubMed), Scopus, SportDiscus, and WOS (Web of Science) databases was performed following the PICO model, using terms related to vegetarians aged between 18 and 64 years who realized an intervention based on strength training and supplementation. Following the PRISMA statement, of the 62 studies found only 3 met all the inclusion criteria and were analyzed entirely to be included in the review. The methodological quality of the studies was performed using the PEDro scale. The study of Shomrat et al. (2000) with creatine supplementation resulted in an increase in body mass and power. The study of Burke et al. (2003), based on creatine supplementation, obtained an increase of phosphocreatine (PCr), total creatine (TCr), strength, type II muscle fibers, and lean tissue. These changes were significant in vegetarians. Finally, in a study of Burke et al. (2008), insulin-like growth factor-1 (IGF-1) increased by 67%, with higher accumulation in the group that was supplemented with creatine. As a consequence of these results we can conclude that creatine supplementation could have positive effects on the performance of vegetarians due to the fact that it could cover certain shortcomings derived from the vegetarian diet.

scholarly journals Effects of Anthocyanin on Intestinal Health: A Systematic Review

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1331
Author(s):  
Thaísa Agrizzi Verediano ◽  
Hércia Stampini Duarte Martino ◽  
Maria Cristina Dias Paes ◽  
Elad Tako
Keyword(s):  
Systematic Review ◽  
Gut Microbiota ◽  
Experimental Studies ◽  
Intestinal Morphology ◽  
Microbiota Composition ◽  
Physical Barrier ◽  
Intestinal Health ◽  
Positive Effects ◽  
Allocation Process ◽  
Gut Microbiota Composition

Intestinal health relies on the association between the mucosal immune system, intestinal barrier and gut microbiota. Bioactive components that affect the gut microbiota composition, epithelial physical barrier and intestinal morphology were previously studied. The current systematic review evaluated evidence of anthocyanin effects and the ability to improve gut microbiota composition, their metabolites and parameters of the physical barrier; this was conducted in order to answer the question: “Does food source or extract of anthocyanin promote changes on intestinal parameters?”. The data analysis was conducted following the PRISMA guidelines with the search performed at PubMed, Cochrane and Scopus databases for experimental studies, and the risk of bias was assessed by the SYRCLE tool. Twenty-seven studies performed in animal models were included, and evaluated for limitations in heterogeneity, methodologies, absence of information regarding allocation process and investigators’ blinding. The data were analyzed, and the anthocyanin supplementation demonstrated positive effects on intestinal health. The main results identified were an increase of Bacteroidetes and a decrease of Firmicutes, an increase of short chain fatty acids production, a decrease of intestinal pH and intestinal permeability, an increase of the number of goblet cells and tight junction proteins and villi improvement in length or height. Thus, the anthocyanin supplementation has a potential effect to improve the intestinal health. PROSPERO (CRD42020204835).

scholarly journals The effectiveness on health education to prevent nipple trauma from breastfeeding: a systematic review

2020 ◽  
Vol 20 (2) ◽  
pp. 333-345
Author(s):  
Flávia Silva Oliveira ◽  
Flaviana Vieira ◽  
Jessica Oliveira Cecilio ◽  
Janaína Valadares Guimarães ◽  
Suzanne Hetzel Campbell
Keyword(s):  
Systematic Review ◽  
Health Education ◽  
Literature Review ◽  
Postpartum Period ◽  
Web Of Science ◽  
Educational Approach ◽  
Level Of Evidence ◽  
Assessment Development ◽  
Positive Effects ◽  
High Level

Abstract Objectives: to analyze the effectiveness on health education to prevent nipple trauma in breastfeeding compared to other interventions. Methods: systematic literature review was carried out in January 2019, according to PRISMA recommendations. The searches were conducted in Cinahl, PubMed, Web of Science, Scopus, and in the references cited in the selected articles. The studies were assessed for quality and level of evidence according to the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE). Results: twelve studies were selected, all conducted at the maternities. The interventions were classified in two categories: health education on breastfeeding and the use of nipple covers. Health education on breastfeeding presents a moderate level of evidence on the prevention of nipple trauma. There is a moderate to high level of evidence on the positive effects of guaiazulene, gel or peppermint water applied in the postpartum period to prevent nipple trauma. Conclusion: health education on breastfeeding with clinical demonstration is an important strategy to prevent nipple trauma and requires more than one educational approach. The use of nipple covers requires some consideration, since they must be removed prior to breastfeeding. All interventions were conducted in the postpartum period, which points out for the necessity of clinical research to prevent nipple trauma in prenatal care.

scholarly journals GUT MICROBIOTA AND THE USE OF PROBIOTICS IN CONSTIPATION IN CHILDREN AND ADOLESCENTS: SYSTEMATIC REVIEW

2020 ◽  
Vol 38 ◽  
Author(s):  
Daiane Oliveira Vale San Gomes ◽  
Mauro Batista de Morais
Keyword(s):  
Systematic Review ◽  
Gut Microbiota ◽  
Children And Adolescents ◽  
Latin American ◽  
Fecal Microbiota ◽  
Specific Pattern ◽  
Complete Control ◽  
Beneficial Effects ◽  
Positive Effects ◽  
Data Source

ABSTRACT Objective: To perform a systematic review of literature data on gut microbiota and the efficacy of probiotics for the treatment of constipation in children and adolescents. Data source: The research was performed in the PubMed, the Scientific Electronic Library Online (SciELO) and the Latin American and Caribbean Health Sciences Literature (LILACS) databases in English, Portuguese and Spanish. All original articles that mentioned the evaluation of the gut microbiota or the use of probiotics in children with constipation in their title and abstract were selected. Data synthesis: 559 articles were found, 47 of which were selected for reading. From these, 12 articles were included; they studied children and adolescents divided into two categories: a gut microbiota evaluation (n=4) and an evaluation of the use of probiotics in constipation therapy (n=8). The four papers that analyzed fecal microbiota used different laboratory methodologies. No typical pattern of gut microbiota was found. Regarding treatment, eight clinical trials with heterogeneous methodologies were found. Fifteen strains of probiotics were evaluated and only one was analyzed in more than one article. Irregular beneficial effects of probiotics have been demonstrated in some manifestations of constipation (bowel frequency or consistency of stool or abdominal pain or pain during a bowel movement or flatulence). In one clinical trial, a complete control of constipation without the use of laxatives was obtained. Conclusions: There is no specific pattern of fecal microbiota abnormalities in constipation. Despite the probiotics’ positive effects on certain characteristics of the intestinal habitat, there is still no evidence to recommend it in the treatment of constipation in pediatrics.

scholarly journals Secretome and Extracellular Vesicles as New Biological Therapies for Knee Osteoarthritis: A Systematic Review

2019 ◽  
Vol 8 (11) ◽  
pp. 1867 ◽  
Author(s):  
Daniele D’Arrigo ◽  
Alice Roffi ◽  
Magali Cucchiarini ◽  
Matteo Moretti ◽  
Christian Candrian ◽  
...  
Keyword(s):  
Systematic Review ◽  
Knee Osteoarthritis ◽  
Extracellular Vesicles ◽  
Web Of Science ◽  
Knee Oa ◽  
Positive Effects ◽  
Biological Approach ◽  
Synovial Tissues

Secretome and extracellular vesicles (EVs) are considered a promising option to exploit mesenchymal stem cells’ (MSCs) properties to address knee osteoarthritis (OA). The aim of this systematic review was to analyze both the in vitro and in vivo literature, in order to understand the potential of secretome and EVs as a minimally invasive injective biological approach. A systematic review of the literature was performed on PubMed, Embase, and Web of Science databases up to 31 August 2019. Twenty studies were analyzed; nine in vitro, nine in vitro and in vivo, and two in vivo. The analysis showed an increasing interest in this emerging field, with overall positive findings. Promising in vitro results were documented in terms of enhanced cell proliferation, reduction of inflammation, and down-regulation of catabolic pathways while promoting anabolic processes. The positive in vitro findings were confirmed in vivo, with studies showing positive effects on cartilage, subchondral bone, and synovial tissues in both OA and osteochondral models. However, several aspects remain to be clarified, such as the different effects induced by EVs and secretome, which is the most suitable cell source and production protocol, and the identification of patients who may benefit more from this new biological approach for knee OA treatment.

scholarly journals Role of Probiotics in Modulating Human Gut Microbiota Populations and Activities in Patients with Colorectal Cancer—A Systematic Review of Clinical Trials

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1160
Author(s):  
Adrianna Wierzbicka ◽  
Dorota Mańkowska-Wierzbicka ◽  
Marcin Mardas ◽  
Marta Stelmach-Mardas
Keyword(s):  
Colorectal Cancer ◽  
Gut Microbiota ◽  
Web Of Science ◽  
Original Research ◽  
Beneficial Bacteria ◽  
Human Gut ◽  
Randomized Controlled ◽  
Inflammatory Parameters ◽  
Gut Barrier Function

Background: Growing attention has been given to the role of nutrition and alterations of microbial diversity of the gut microbiota in colorectal cancer (CRC) pathogenesis. It has been suggested that probiotics and synbiotics modulate enteric microbiota and therefore may be used as an intervention to reduce the risk of CRC. The aim of this study was to evaluate the influence of probiotics/synbiotics administration on gut microbiota in patients with CRC. Methods: PubMed, Scopus, and Web of Science were searched between December 2020 and January 2021. Randomized controlled trials (RCTs) recruiting adults with CRC, who have taken probiotics/synbiotics for at least 6 days were included. Changes in gut microbiota and selected biochemical and inflammatory parameters (i.e., hsCRP, IL-2, hemoglobin) were retrieved. Results: The search resulted in 198 original research articles and a final 6 were selected as being eligible, including 457 subjects. The median age of patients was 65.4 years old and they were characterized by the median BMI value: 23.8 kg/m2. The literature search revealed that probiotic/synbiotic administration improved enteric microbiota by increasing the abundance of beneficial bacteria such as Lactobacillus, Eubacterium, Peptostreptococcus, Bacillus and Bifidobacterium, and decreased the abundance of potentially harmful bacteria such as Fusobacterium, Porhyromonas, Pseudomonas and Enterococcus. Additionally, probiotic/synbiotic intervention improved release of antimicrobials, intestinal permeability, tight junction function in CRC patients. Conclusions: The use of probiotics/synbiotics positively modulates enteric microbiota, improves postoperative outcomes, gut barrier function and reduces inflammatory parameters in patients suffering from CRC.

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