scholarly journals Long-term antimicrobial effectiveness of a silver-impregnated foil on high-touch hospital surfaces in patient rooms

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Andreas F. Widmer ◽  
Sonja Kuster ◽  
Marc Dangel ◽  
Sammy Jäger ◽  
Reno Frei
Keyword(s):  
Controlled Trial ◽  
Silver Ions ◽  
Hospital Environment ◽  
Mean Values ◽  
Hospital Acquired Infection ◽  
Log Reduction ◽  
Bacterial Transmission ◽  
Cleaning And Disinfection ◽  
Hospital Acquired ◽  
Antimicrobial Effectiveness

Abstract Background The hospital environment has got more attention as evidence as source for bacterial transmission and subsequent hospital-acquired infection increased. Regular cleaning and disinfection have been proposed to lower the risk of infection, in particular for gram-positive bacteria. Auto-disinfecting surfaces would allow to decrease survival of pathogens, while limiting resource to achieve a safe environment in patient rooms. Methods A controlled trial to evaluate the antimicrobial effectiveness of a polyvinyl chloride foil containing an integrated silver-based agent (containing silver ions 2%) on high-touch surfaces in patient rooms. Results The overall log reduction of the mean values was 1.8 log10 CFU, the median 0.5 log10 CFU comparing bioburden of control vs antimicrobial foil (p < 0.01). Important pathogens were significantly less likely recovered from the foil, in particular enterococci. These effects were present even after 6 months of in-use. Conclusions A foil containing an integrated silver-based agent applied to high-touch surfaces effectively results in lower recovery of important pathogens from such surfaces over a 6-month study period.

scholarly journals EMERGENCE AND ANTIBIOTIC SENSITIVITY PATTERN OF ACINETOBACTER BAUMANNII IN HOSPITAL FACILITY

2017 ◽  
Vol 10 (3) ◽  
pp. 77
Author(s):  
Anania Arjuna ◽  
Dinobandhu Nandi
Keyword(s):  
Acinetobacter Baumannii ◽  
Nosocomial Infections ◽  
Antibiotic Sensitivity ◽  
Hospital Environment ◽  
Sensitivity Testing ◽  
Hospital Acquired Infection ◽  
Clinical Specimens ◽  
Sensitivity Pattern ◽  
Tract Infections ◽  
Hospital Acquired

ABSTRACTObjective: Nosocomial infections or Hospital acquired infection (HAI) are one of the major threats to hospitalized patients as well as for the hospitalassociated personnel. In last few years there is a gross change in causative agents, new organisms have come out with great threat to hospitals as theypossess antibiotic resistance property e.g. production of biofilm, production of enzymes such as β- lactamases. Among many organisms, Acinetobacterbaumannii has emerged as a potent nosocomial pathogen. Our objective of this study was to find the burden of Acinetobacter baumannii infectionswhich are associated as nosocomial infections and to determine the drug of choice for an effective treatment.Methods: Clinical specimens were collected from patients of different unit of the hospital by maintaining universal precautions and standardmicrobiological protocols. All the respective specimens were cultured in respective culture medium i.e. MacConkey agar, blood agar, chocolate agar,cysteine lactose electrolyte deficient (CLED) agar and, fluid thioglycolate (TG) medium at 37˚C for 24-48 hours. After incubation of 24-48 hours cultureplates were examined for bacterial growth and identification and antibiotic sensitivity test was made by Vitek2 compact.Result: The study was conducted at the department of microbiology from January 2016 to April 2016. A total of 2582 specimens were collected andprocessed for identification and sensitivity testing. Specimens of all age group (2 days- 93 years) and both sexes were processed for identificationof A. baumannii and antibiotic sensitivity testing. A total of 119 isolates (4.60%) of A. baumannii were obtained from 2582 clinical specimens. Themost common infection A. baumannii was found as lower respiratory tract infection (89.07%) followed by abscess (6.72%), septicaemia (2.52%),urinary tract infections (0.84%), and soft tissue infections (0.84%). The maximum sensitivity of A. baumannii isolates were seen to Colistin (CL) (119,100%), followed by Tigecycline (TGC) (63, 52.94%) and Minocycline (MIN) (27, 22.69%). The maximum resistant was observed for Imipenem (IMI),Aztreonam (AZT) and Ticarcillin- clavulanic acid (TIC) (119, 100%).Conclusion: The Gram- negative coccobacillus, Acinetobacter baumannii poses a formidable threat to patients. It has emerged as a superbug inhospital environment particularly in ICU units. The chances of A. baumannii infections increase in the presence of iatrogenic factors like inadequatelong- term antibiotic therapy and new interventions in a medical facility. To control the burden of Acinetobacter infections new therapies suchas combine therapy must be obtained and followed with proper dose as recommend by physicians; along with awareness of the importance ofthis infection should be implicated. Proper sanitation, good housekeeping, sterilization of equipment, hand hygiene, water purification, isolationprocedures and maintaining of the hospital environment, use of infection control practices are some of the measures to control the transmission ofAcinetobacter spp. among hospital personnel.Keywords: Acinetobacter baumannii, Biofilm, β-lactamases, Hospital acquired infection.

scholarly journals Airborne transmission of disease in hospitals

2009 ◽  
Vol 6 (suppl_6) ◽  
Author(s):  
I. Eames ◽  
J. W. Tang ◽  
Y. Li ◽  
P. Wilson
Keyword(s):  
Hospital Environment ◽  
Public Health Issue ◽  
Airborne Transmission ◽  
Indirect Contact ◽  
Hospital Acquired Infection ◽  
Engineering Sciences ◽  
Contact Transmission ◽  
Hospital Acquired ◽  
Scientific Questions ◽  
Transmission Of Disease

Hospital-acquired infection (HAI) is an important public health issue with unacceptable levels of morbidity and mortality, over the last 5 years. Disease can be transmitted by air (over large distances), by direct/indirect contact or a combination of both routes. While contact transmission of disease forms the majority of HAI cases, transmission through the air is harder to control, but one where the engineering sciences can play an important role in limiting the spread. This forms the focus of this themed volume. In this paper, we describe the current hospital environment and review the contributions from microbiologists, mechanical and civil engineers, and mathematicians to this themed volume on the airborne transmission of infection in hospitals. The review also points out some of the outstanding scientific questions and possible approaches to mitigating transmission.

scholarly journals Hospital-acquired Sphingomonas paucimobilis Infection in a Neonate: A Case Report

2020 ◽  
pp. 42-46
Author(s):  
Ahaneku Iherue Osuji ◽  
Jennifer Eneyi Imaji ◽  
Eyinade Kudirat Olateju ◽  
Bissallah Ahmed Ekele ◽  
Nicholas Baamlong ◽  
...  
Keyword(s):  
Complete Blood Count ◽  
Opportunistic Pathogen ◽  
Hospital Environment ◽  
Sphingomonas Paucimobilis ◽  
Laboratory Findings ◽  
Adequate Treatment ◽  
Hospital Acquired Infection ◽  
Pseudomonas Paucimobilis ◽  
The University ◽  
Hospital Acquired

Introduction: The organism Sphingomonas paucimobilis formerly known as Pseudomonas paucimobilis is a strict aerobe, motile, non-spore forming, non-fermentative, Gram-negative bacillus, characterized by catalase and oxidase activities. It is an opportunistic pathogen that causes infection in healthy and immunocompromised individuals. Sphingomonas paucimobilis is ubiquitous and has been isolated from diverse sources including the hospital environment. Presentation of Case: We describe the clinical characteristics, manifestations, laboratory findings and management of hospital-acquired Sphingomonas paucimobilis sepsis in a neonate, delivered through caesarean section and brought in from postnatal ward to special care baby unit of the University of Abuja Teaching Hospital, Gwagwalada, Abuja, Nigeria. Discussion: The laboratory findings showed normal values for complete blood count, electrolytes, urea and creatinine but positive blood culture. Sphingomonas paucimobilis isolated from the blood was susceptible to Imipenem, Ampicilin-sulbatam, Azithromycin, Lincomycin, Ofloxacin, Ciprofloxacin and Sparfloxacin but resistant to Cefuroxime, Ceftazidime, Augumentin and Ampicillin. The isolation of this organism from the newborn whose laboratory tests were within normal acceptable values, and from the hospital environment is a case of hospital-acquired infection. The patient recovered and was discharged because of adequate treatment by the managing team and also low virulence of this organism. Conclusion: The study thereby recommends adequate and consistent cleaning of the newborn and maternity units of the hospital, in particular, the entire hospital equipment and its environment using a potent disinfectant to minimize the risk of hospital-acquired infections.

scholarly journals Association between intrahospital transfer and hospital-acquired infection in the elderly: a retrospective case–control study in a UK hospital network

2021 ◽  
pp. bmjqs-2020-012124 ◽  
Author(s):  
Emanuela Estera Boncea ◽  
Paul Expert ◽  
Kate Honeyford ◽  
Anne Kinderlerer ◽  
Colin Mitchell ◽  
...  
Keyword(s):  
Case Control Study ◽  
Multivariable Analysis ◽  
Case Control ◽  
Pathogen Transmission ◽  
Hospital Environment ◽  
High Risk Population ◽  
Retrospective Case ◽  
Hospital Acquired Infection ◽  
Hospital Acquired ◽  
Control Study

BackgroundIntrahospital transfers have become more common as hospital staff balance patient needs with bed availability. However, this may leave patients more vulnerable to potential pathogen transmission routes via increased exposure to contaminated surfaces and contacts with individuals.ObjectiveThis study aimed to quantify the association between the number of intrahospital transfers undergone during a hospital spell and the development of a hospital-acquired infection (HAI).MethodsA retrospective case–control study was conducted using data extracted from electronic health records and microbiology cultures of non-elective, medical admissions to a large urban hospital network which consists of three hospital sites between 2015 and 2018 (n=24 240). As elderly patients comprise a large proportion of hospital users and are a high-risk population for HAIs, the analysis focused on those aged 65 years or over. Logistic regression was conducted to obtain the OR for developing an HAI as a function of intrahospital transfers until onset of HAI for cases, or hospital discharge for controls, while controlling for age, gender, time at risk, Elixhauser comorbidities, hospital site of admission, specialty of the dominant healthcare professional providing care, intensive care admission, total number of procedures and discharge destination.ResultsOf the 24 240 spells, 2877 cases were included in the analysis. 72.2% of spells contained at least one intrahospital transfer. On multivariable analysis, each additional intrahospital transfer increased the odds of acquiring an HAI by 9% (OR=1.09; 95% CI 1.05 to 1.13).ConclusionIntrahospital transfers are associated with increased odds of developing an HAI. Strategies for minimising intrahospital transfers should be considered, and further research is needed to identify unnecessary transfers. Their reduction may diminish spread of contagious pathogens in the hospital environment.

Effectiveness of Chlorhexidine Wipes for the Prevention of Multidrug-Resistant Bacterial Colonization and Hospital-Acquired Infections in Intensive Care Unit Patients: A Randomized Trial in Thailand

2015 ◽  
Vol 37 (3) ◽  
pp. 245-253 ◽  
Author(s):  
Adhiratha Boonyasiri ◽  
Peerapat Thaisiam ◽  
Chairat Permpikul ◽  
Tepnimitr Judaeng ◽  
Bordeesuda Suiwongsa ◽  
...  
Keyword(s):  
Intensive Care ◽  
Hospital Stay ◽  
Bacterial Colonization ◽  
Controlled Trial ◽  
Multidrug Resistant ◽  
Control Group ◽  
Open Label ◽  
Skin Reactions ◽  
Hospital Acquired Infection ◽  
Hospital Acquired

OBJECTIVETo determine the effectiveness of daily bathing with 2% chlorhexidine-impregnated washcloths in preventing multidrug-resistant (MDR) gram-positive bacterial colonization and bloodstream infection.METHODSA randomized, open-label controlled trial was conducted in 4 medical intensive care units (ICUs) in Thailand from December 2013 to January 2015. Patients were randomized to receive cleansing with non-antimicrobial soap (control group) or 2% chlorhexidine-impregnated washcloths used to wipe the patient’s body once daily (chlorhexidine group). Swabs were taken from nares, axilla, antecubital, groin, and perianal areas on admission and on day 3, 5, 7, and 14. The 5 outcomes were (1) favorable events ( all samples negative throughout ICU admission, or initially positive samples with subsequent negative samples); (2) MDR bacteria colonization-free time; (3) hospital-acquired infection; (4) length of ICU and hospital stay; (5) adverse skin reactions.RESULTSA total of 481 patients were randomly assigned to the control group (241) or the chlorhexidine group (240). Favorable events at day 14 were observed in 34.8% of patients in the control group and 28.6% in the chlorhexidine group (P=.79). Median MDR bacteria colonization-free times were 5 days in both groups. The incidence rate of hospital-acquired infection and the length of the ICU and hospital stay did not differ significantly between groups. The incidence of adverse skin reactions in the chlorhexidine group was 2.5%.CONCLUSIONThe effectiveness of 2% chlorhexidine-impregnated washcloths for the prevention of MDR gram-negative bacteria colonization and hospital-acquired infection in adult patients in ICU was not proven.TRIAL REGISTRATIONClinicalTrials.gov identifier: NCT01989416.Infect. Control Hosp. Epidemiol. 2016;37(3):245–253

scholarly journals Association between intrahospital transfers and hospital-acquired infection among elderly patients: A retrospective case-control study in one urban UK hospital trust

2020 ◽  
Author(s):  
Estera Boncea ◽  
Paul Expert ◽  
Kate Honeyford ◽  
Anne Kinderlerer ◽  
Colin Mitchell ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Case Control Study ◽  
Case Control ◽  
Pathogen Transmission ◽  
Hospital Environment ◽  
Retrospective Case ◽  
Hospital Acquired Infection ◽  
Hospital Trust ◽  
Hospital Acquired ◽  
Control Study

AbstractBackgroundIntrahospital transfers have become more common as hospital staff balance patient needs with bed availability. However, this may leave patients more vulnerable to potential pathogen transmission routes via increased exposure to contaminated surfaces and contacts with individuals.ObjectiveThis study aimed to quantify the association between the number of intrahospital transfers undergone during a hospital spell and the development of a hospital-acquired infection (HAI).MethodsA retrospective case-control study was conducted using data extracted from electronic health records and microbiology cultures of non-elective, medical admissions to a large urban hospital trust comprising 3 hospital sites between 2016 and 2018 (n=24,239). As elderly patients comprise a large proportion of hospital users and are a high-risk population for HAIs, the analysis focused on those over 65-years old. Logistic regression was conducted to obtain the odds ratio (OR) for developing a HAI as a function of intrahospital transfers until onset of HAI for cases, or hospital discharge for controls, while controlling for age, gender, time-at-risk, Elixhauser comorbidities, hospital site of admission, dominant treatment function code, intensive care admission, total number of procedures, and discharge destination.ResultsOf the 24,239 spells, 2879 cases were included in the analysis. 72.2% of spells contained at least one intrahospital transfer. On multivariable analysis, each additional intrahospital transfer increased the odds of acquiring a HAI by 9% (OR 1.09; 95%CI 1.05 to 1.13).ConclusionIntrahospital transfers are associated with increased odds of developing a HAI. Strategies for minimising intrahospital transfers should be considered, and further research is needed to identify unnecessary transfers. Their reduction may diminish spread of contagious pathogens in the hospital environment.

scholarly journals Salmonella serotypes, Salmonella typhi phage types, and anti-microbial resistance at the University Hospital of the West Indies, Jamaica

1977 ◽  
Vol 79 (1) ◽  
pp. 5-16 ◽  
Author(s):  
G. L. French ◽  
S. D. King ◽  
P. St Louis
Keyword(s):  
Salmonella Typhi ◽  
University Hospital ◽  
Hospital Environment ◽  
Sensitivity Testing ◽  
Hospital Acquired Infection ◽  
Phage Types ◽  
Striking Change ◽  
Paratyphoid Fever ◽  
The University ◽  
Hospital Acquired

SUMMARYBacteriologically proved cases of salmonellosis presenting at the University Hospital have increased nearly threefold since 1957. The most striking change has been a considerable increase in the incidence of Salmonella heidelberg and Salmonella derby in the last 5 years, probably resulting from hospital acquired infection.About 80 cases of typhoid fever are reported each year in Jamaica. There has been little change in the prevalence of different phage types of Salmonella typhi since 1961. Paratyphoid fever is rare.Standardized antimicrobial disk-sensitivity testing was performed on selected surviving salmonella strains since 1964. S. typhi has remained fully sensitive to all the agents tested except streptomycin. Other salmonellas, however have shown a significant increase in antimicrobial resistance since 1970. Most of this increase was due to multiple resistance in S. heidelberg and S. derby, and the survival and dissemination of these strains in the hospital environment may be related to antibiotic usage.

Isolation of post operative hospital acquired infections in a private hospital of Bangladesh and identification of clonal relatedness of E. coli by using Pulse filed gel electrophoresis

2012 ◽  
Vol 6 (2) ◽  
pp. 7-10
Author(s):  
Mohammad Murshed ◽  
Sabeena Shahnaz ◽  
Md. Abdul Malek
Keyword(s):  
Private Hospital ◽  
Isolation And Identification ◽  
College Hospital ◽  
Hospital Acquired Infection ◽  
E Coli ◽  
Hospital Acquired Infections ◽  
Medical College ◽  
Clonal Relatedness ◽  
Hospital Acquired ◽  
Dressing Materials

Isolation and identification of post operative hospital acquired infection was carried out from July 2008 to December 2008 in Holy Family Red Crescent Medical College Hospital (private hospital). The major pathogen of wound infection was E. coli. A total; of 120 samples were collected from the surrounding environment of post operative room like floor, bed sheets, instruments, dressing materials, catheter, nasogastric and endotracheal tube. E. coli (40%) was the predominant organism followed by S. aureus (24%). DNA fingerprinting analysis using pulsed field gel electreopheresis of XbaI restriction digested genomic DNA showed that clonal relatedness between the two clinical nd environmental isolates were 100%.DOI: http://dx.doi.org/10.3329/bjmm.v6i2.19369 Bangladesh J Med Microbiol 2012; 06(02): 7-10

Sign in / Sign up

Export Citation Format

Share Document