scholarly journals Quantification, description and international comparison of antimicrobial use on Irish pig farms

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Lorcan O’Neill ◽  
Maria Rodrigues da Costa ◽  
Finola C. Leonard ◽  
James Gibbons ◽  
Julia Adriana Calderón Díaz ◽  
...  

Abstract Background There is concern that the use of antimicrobials in livestock production has a role in the emergence and dissemination of antimicrobial resistance in animals and humans. Consequently, there are increasing efforts to reduce antimicrobial use (AMU) in agriculture. As the largest consumer of veterinary antimicrobials in several countries, the pig sector is a particular focus of these efforts. Data on AMU in pig production in Ireland are lacking. This study aimed to quantify AMU on Irish pig farms, to identify the major patterns of use employed and to compare the results obtained to those from other published reports and studies. Results Antimicrobial use data for 2016 was collected from 67 Irish pig farms which represented c. 35% of national production. The combined sample population consumed 14.5 t of antimicrobial by weight of active ingredient suggesting that the pig sector accounted for approximately 40% of veterinary AMU in Ireland in 2016. At farm level, median AMU measured in milligram per population correction unit (mg/PCU) was 93.9 (range: 1.0–1196.0). When measured in terms of treatment incidence (TI200), median AMU was 15.4 (range: 0.2–169.2). Oral treatments accounted for 97.5% of all AMU by weight of active ingredient and were primarily administered via medicated feed to pigs in the post weaning stages of production. AMU in Irish pig production in 2016 was higher than results obtained from the national reports of Sweden, Denmark, the Netherlands and France but lower than the United Kingdom. Conclusions Pig production in Ireland is an important consumer of veterinary antimicrobials. The quantities and patterns of AMU on Irish pig farms are comparable to pig production in other European countries but higher than some countries with more advanced AMU reduction strategies. This AMU is characterised by a high proportion of prophylactic use and is primarily administered to pigs post weaning via medicated feed. Further studies to better understand the reasons for AMU on Irish pig farms and strategies to improve health among weaner pigs will be of benefit in the effort to reduce AMU.

Animals ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 2828
Author(s):  
Lorcan O’Neill ◽  
Julia Adriana Calderón Díaz ◽  
Maria Rodrigues da Costa ◽  
Sinnead Oakes ◽  
Finola C. Leonard ◽  
...  

The threat to public health posed by antimicrobial resistance in livestock production means that the pig sector is a particular focus for efforts to reduce antimicrobial use (AMU). This study sought to investigate the risk factors for AMU in Irish pig production. Antimicrobial use data were collected from 52 farrow-to-finish farms. The risk factors investigated were farm characteristics and performance, biosecurity practices, prevalence of pluck lesions at slaughter and serological status for four common respiratory pathogens and vaccination and prophylactic AMU practices. Linear regression models were used for quantitative AMU analysis and risk factors for specific AMU practices were investigated using logistic regression. Farms that milled their own feed had lower total AMU (p < 0.001), whereas higher finisher mortality (p = 0.043) and vaccinating for swine influenza (p < 0.001) increased AMU. Farms with higher prevalence of pericarditis (p = 0.037) and lung abscesses (p = 0.046) used more group treatments. Farms with higher prevalence of liver milk spot lesions (p = 0.018) and farms practising prophylactic AMU in piglets (p = 0.03) had higher numbers of individual treatments. Farms practising prophylactic AMU in piglets (p = 0.002) or sows (p = 0.062) had higher use of cephalosporins and fluoroquinolones. This study identified prophylactic use and respiratory disease as the main drivers for AMU in Irish pig production. These findings highlight areas of farm management where interventions may aid in reducing AMU on Irish pig farms.


Insects ◽  
2021 ◽  
Vol 12 (6) ◽  
pp. 548
Author(s):  
Samantha Mirhaya de Silva ◽  
David Chesmore ◽  
Jack Smith ◽  
Gordon Port

Gastropod damage to crop plants has a significant economic impact on agricultural and horticultural industries worldwide, with the Grey Field Slug (Deroceras reticulatum (Müller)) considered the main mollusc pest in the United Kingdom and in many other temperate areas. The prevailing form of crop protection is pellets containing the active ingredient, metaldehyde. Metaldehyde can cause paralysis and death in the mollusc, depending on the amount ingested. The paralysing effects may result in reduced pellet consumption. A greater understanding of metaldehyde consumption may reveal an area that can be manipulated using novel molluscicide formulations. Novel pellet types included commercial metaldehyde pellets coated so that metaldehyde is released more slowly. In both laboratory and arena trials, an audio sensor was used to record individual slugs feeding on a variety of pellet types, including commercially available toxic pellets (metaldehyde and ferric phosphate) and novel metaldehyde formulations. The sensor was used to record the length of each bite and the total number of bites. There was no significant difference in the length of bites between pellet types in laboratory trials. Novel pellets were not consumed more than commercial pellet types. Commercial pellet types did not differ in consumption.


2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Abdurrahman Hassan Jibril ◽  
Iruka N. Okeke ◽  
Anders Dalsgaard ◽  
John Elmerdahl Olsen

Abstract Background Antimicrobial resistance (AMR) is a global health threat affecting treatment outcome in animals and humans. A pre-requisite for development of AMR reduction strategies is knowledge of antimicrobial use patterns, and how these affect resistance development. The aim of this study was to determine antimicrobial usage (AMU) and whether such usage was associated with AMR in Salmonella from poultry farms in Northwest Nigeria. Results Fifteen (37%) of antimicrobial products observed contained compounds that are of highest priority and critically important for human medicine. Broilers chicken consumed higher (28 ± 14 mg/kg active ingredients) amounts of antimicrobials compared to layers (13 ± 8 mg/kg) per week (p = 0.0009). Surprisingly, chickens raised under backyard system consumed higher amounts of antimicrobials (34 ± 7 mg/kg) than poultry in other systems (p = 0.02). High levels of resistance to tetracycline (58%), sulphonamides (65%), ciprofloxacin (46%) and gentamicin (42%) correlated with high farm level usage of these antimicrobials, and there was a strong correlation (r = 0.9) between farm usage and resistance of isolates to the same antimicrobials (p = 0.03). Conclusion High AMU, including use of highest priority critically important antimicrobials was observed at poultry farms in Northwest Nigeria. AMU correlated with high levels of resistance. Communication of prudent use of antimicrobials to farmers and regulation to obtain reduction in AMU should be a priority.


2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Esther Martínez-Pastor ◽  
Ricardo Vizcaíno-Laorga ◽  
David Atauri-Mezquida

Abstract This paper analyzes the data collected about 5,388 videos from the 15 leading channels from Spain, the United Kingdom, and the United States focusing on toys and in which the protagonists are children under 14 years of age (2011–2019). It aims to determine whether there are common patterns of use, production, and activity in videos by kid YouTubers. Specific software was developed to enable information to be gathered from the YouTube platform through the YouTube Data API by analyzing the date on which the video was published, length, number of visits, likes, dislikes, and visits/vote (visits/[likes+dislikes]). The main conclusions drawn are that a channel’s success is not dependent on a pattern or specific characteristics, although an impulse pattern has been detected; participation by children who consume content in the United States differs significantly from participation by those in Europe; and certain similarities based on video length and production frequency can be observed between channels.


2019 ◽  
Vol 20 (3) ◽  
pp. 223-232 ◽  
Author(s):  
Jenny V. Morris ◽  
Melpo Kapetanstrataki ◽  
Roger C. Parslow ◽  
Peter J. Davis ◽  
Padmanabhan Ramnarayan

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S374-S374
Author(s):  
Christopher J Graber ◽  
Makoto M Jones ◽  
Matthew B Goetz ◽  
Karl Madaras-Kelly ◽  
Yue Zhang ◽  
...  

Abstract Background To identify areas for improved antibiotic use, we developed and pilot-tested visualization tools to quantify antibiotic use at 8 VA facilities. These tools allow a facility to review its patterns of total use, and use by antibiotic class, compared with patterns of use at VA facilities with similar (or user-selected) complexity levels. Methods Antibiotic stewards from 8 VA facilities participated in iterative report development and implementation, with the final product consisting of two components: an interactive web-based antibiotic dashboard and a standardized antibiotic usage report updated at user-selected intervals. Stewards also participated in monthly learning collaboratives. The percent change in average monthly antimicrobial use (all antibiotics; anti-methicillin-resistant S. aureus agents (anti-MRSA); and broad-spectrum agents predominantly used for hospital-onset/multi-drug-resistant organisms (anti-MDRO)) was analyzed using a pre-post (January 2014–January 2016 vs. July 2016–January 2018) with un-involved controls (all other inpatient VA facilities, n = 132) design modeled using Generalized Estimation Equations segmented regression. Results Intervention sites had a 2.1% decrease (95% CI = [−5.7%,1.6%]) in all antibiotic use pre-post-intervention, vs. a 2.5% increase (95% CI = [0.8%, 4.1%]) in nonintervention sites (P = 0.025 for difference). Anti-MRSA antibiotic use decreased 11.3% (95% CI = [−16.0%,−6.3%]) at intervention sites vs. a 6.6% decrease (95% CI=[−9.1%, −3.9%]) at nonintervention sites (P = 0.092 for difference). Anti-MDRO antibiotic use decreased 3.4% (95% CI = [−8.2%,1.7%]) at intervention sites vs. a 3.6% increase (95% CI = [0.8%,6.5%]) at nonintervention sites (P = 0.018 for difference) (Figure 1). Examples of graphs include overall antibacterial use (Figure 2), and usage of broad-spectrum Gram-negative therapy (Figure 3) in intensive care units. Conclusion The use of data visualization tools use and participation in monthly learning collaboratives by antimicrobial stewards in a pilot implementation project at eight VA facilities was associated with decreases in antimicrobial use relative to uninvolved sites. Disclosures All authors: No reported disclosures.


2020 ◽  
Vol 7 ◽  
Author(s):  
Nele Caekebeke ◽  
Franca J. Jonquiere ◽  
Moniek Ringenier ◽  
Tijs J. Tobias ◽  
Merel Postma ◽  
...  

2014 ◽  
Vol 25 (2) ◽  
pp. 103-106 ◽  
Author(s):  
Shiona K Glass-Kaastra ◽  
Rita Finley ◽  
Jim Hutchinson ◽  
David M Patrick ◽  
Karl Weiss ◽  
...  

INTRODUCTION: Because antimicrobial use is commonly associated with the development of antimicrobial resistance, monitoring the volume and patterns of use of these agents is very important.OBJECTIVE: To assess the use of macrolide and lincosamide (ML) antimicrobials within Canadian provinces over time, and to compare use rates with those reported by European countries.METHODS: Antimicrobial prescribing data were used to develop two yearly metrics: prescriptions per 1000 inhabitant-days (PrIDs) and the mean defined daily doses (DDDs) per prescription, which were then used to build linear mixed models to assess differences among provinces over time.RESULTS: After accounting for repeated measures over time, prescribing rates (PrIDs) varied significantly according to province and year (P<0.001). However, little change occurred within each province over the time frame studied; from 1995 to 2010, each province had a PrID change <0.01. Quebec and British Columbia had significantly lower prescribing rates than all other provinces. No overall secular trend was apparent. In contrast, the DDDs per prescription did not vary significantly according to province, but showed a significant year-to-year increase.DISCUSSION: ML prescribing varied among provinces in Canada between 1995 and 2010, but remained relatively stable within each province. The average DDDs per ML prescription did not vary according to province, but increased linearly over time. These increases are likely to indicate that fewer prescriptions are being written for children over time, a practice supported by good antimicrobial stewardship principles.


2009 ◽  
Vol 2009 ◽  
pp. 37-37
Author(s):  
A O K Adesehinwa ◽  
J O Saka

The significant contribution of pig production in the supply of high quality protein in Nigeria is evident in the rapid increase in number of pig farms witnessed recently. However, African Swine Fever (ASF) has since ravaged pig farms and consequently resulted in loss of farmers’ investments especially in some parts of the Southwest Agro-ecological zone of Nigeria (Majiyagbe et al., 2004; Otesile et al., 2005; Olugasa and Ijagbone, 2007). Putting the growth of the enterprise back on track requires proper assessment of the socio-economic environment surrounding the spread of the disease with the aim of determining the extent of infection, the consequences in terms of mortality of animals and loss of revenue alongside identifying farm specific factors that could have contributed to the spread. This study thus investigated the incidence of ASF and its socio-economic implications on pig enterprise in the zone.


Sign in / Sign up

Export Citation Format

Share Document