scholarly journals Prevalence Trends of Metabolic Syndrome Among Korean Children and Adolescents From 2007 to 2018

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A719-A720
Author(s):  
Jihyun Kim ◽  
Jungsub Lim
Keyword(s):  
Metabolic Syndrome ◽  
Children And Adolescents ◽  
Dietary Habits ◽  
Sodium Intake ◽  
Fasting Blood Glucose ◽  
Normal Weight ◽  
Nutrition Survey ◽  
Future Health ◽  
Korean Children ◽  
Korean Adolescents

Abstract Background: The prevalence of metabolic syndrome (MetS) in adults is increasing worldwide. The change of cardiovascular structure associated with metabolic syndrome appears from childhood, it is crucial to detect MetS early, and control associated risk factors to protect future health. Methods: We used data of children and adolescents (8,718 subjects aged 10-18) from the National Health and Nutrition Survey IV-VII (KNHANES 2007-2018) to estimate the recent prevalence of MetS, and identify related nutritional factors. The definition of MetS used modified NCEP-ATP III and IDF criteria. Results: The prevalence of MetS among Korean adolescents in 2007-2018 was 4.6% using the modified NCEP-ATP III criteria, and the trend of MetS increased significantly (P trend=0.02). In the overweight and obese groups, the risk of MetS increased 7.079 (95% CI, 5.188-9.793) and 27.131 (95% CI, 20.896-35.240) compared to the normal-weight group. During KNHANES IV-VII, overall caloric intake increased, carbohydrate and sodium intake decreased, but fat intake increased (KNHANE-IV; 21.3% to VII; 24.0%, P <0.001). These fat intakes were significantly correlated with an increase in systolic blood pressure, fasting blood glucose, and waist circumference. Conclusion: The prevalence of MetS is also increasing in Korean adolescents, and changes in dietary habits are related. In the future, it is also necessary to study the relationship with lifestyle.

scholarly journals Gender-based differences in the clustering of metabolic syndrome factors in children and adolescents

2020 ◽  
Vol 33 (2) ◽  
pp. 279-288 ◽  
Author(s):  
Valeria Calcaterra ◽  
Daniela Larizza ◽  
Annalisa De Silvestri ◽  
Riccardo Albertini ◽  
Federica Vinci ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Children And Adolescents ◽  
Fasting Blood Glucose ◽  
Treatment Strategies ◽  
Normal Weight ◽  
Model Assessment ◽  
Significant Difference ◽  
Gender Based

AbstractBackgroundWe depicted gender-differences in metabolic syndrome (MS) clustering before and after puberty in pediatrics, in order to develop gender specific preventive strategies for childhood obesity.MethodsWe considered 1079 children and adolescents (529 females and 550 males; mean age 11.5 ± 2.8 year). According to body mass index (BMI) percentiles the subjects were classified as normal weight BMI <75th, overweight BMI 75–95th and with obesity BMI >95th. MS was diagnosed when three of the following criteria for age and sex percentiles were met: BMI >95th, triglycerides (TGs) level >95th, high-density lipoprotein-cholesterol (HDL-c) level <5th, blood pressure (blood pressure) >95th percentile, fasting blood glucose (FBG) >100 mg/dL and/or homeostatic model assessment- insulin resistance (HOMA-IR) >97.5th percentile.ResultsThe prevalence of dismetabolic factors was similar in both genders, except for pathological BP, which was higher in males (p = 0.02). MS was detected only in patients with obesity, with a higher prevalence in pubertal than late/post-pubertal subjects (p < 0.001), without any significant difference between gender. In pre-puberty, the most common MS combination was obesity (HBMI) + hypertension (HBP) + hyperglycemia/insulin resistance (HGLY/IR) followed by HBMI + low HDL-levels (LHDL) + HGLY/IR versus HBMI + HBP + HGLY/IR followed by HBMI + HBP + LHDL, respectively, in females and males. In the early and late/post-pubertal periods, the most prevalent combination remained similar to pre-puberty, additionally in both sexes other combinations, such as HBMI + HTG + HBP + HGLY/IR, HBMI +  HBP + LHDL + HGLY/IR, HBMI + HTG + LHDL + HGLY/IR and HBMI + HTG + LHDL + HBP + HGLY/IR were also detected, differently distributed in males and females.ConclusionsWe confirm that MS is an important consequence related to obesity, particularly in the post-puberty stage. Some gender-based differences should be considered early in order to identify specific preventive and treatment strategies.

Changes in metabolic syndrome of Korean children and adolescents in the period 1998 to 2001

2008 ◽  
Vol 31 (4) ◽  
pp. 327-333 ◽  
Author(s):  
S. Lim ◽  
H. C. Jang ◽  
K. S. Park ◽  
H. K. Lee ◽  
H. R. Chung ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Children And Adolescents ◽  
Korean Children

scholarly journals Metabolic characteristics and nutrition intake on women with normal body mass index

Food Research ◽  
2020 ◽  
Vol 4 (S3) ◽  
pp. 6-12
Author(s):  
D.Y. Fitranti ◽  
F.F. Dieny ◽  
D.M. Kurniawati ◽  
R. Purwanti ◽  
B. Kusumaningnastiti ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Blood Glucose ◽  
Fasting Blood Glucose ◽  
Hdl Cholesterol ◽  
Normal Weight ◽  
Normal Body Mass Index ◽  
Metabolic Characteristics ◽  
Low Hdl ◽  
Nutrition Intake

Metabolic syndrome can be found on an individual with normal weight (Metabolically Obese Normal Weight/MONW). Eating habits and lifestyle changing in early adulthood can be the risk of metabolic syndrome in person with a normal body mass index (BMI). The purpose of this study was to identify metabolic characteristics in women with normal BMI and to analyze the correlation of nutrition intake with metabolic syndrome on women with normal BMI. This is an observational study with a cross-sectional design at five offices in Semarang. The sample in this study was 64 subjects. Inclusion criteria of study subject were women aged 25-40 years and BMI <25 kg/m2 . Study subject was chosen by using a consecutive sampling method. The data of nutrition intake was obtained by using the Food Frequency Questionnaire. HDL cholesterol, fasting blood glucose and triglyceride were analyzed. Analysis data was conducted by using Pearson correlation and Rank Spearman. MONW was present in 10.9% and more than 50% had pre metabolic syndrome. A total of 51.6% of the subjects had central obese and 26.6% had low HDL cholesterol. About 14.1% of the subjects have hypertension. There was a positive correlation between energy, fat intake and waist circumference. Carbohydrate intake was positively correlated with fasting blood glucose and triglyceride. The higher protein intake, the higher HDL cholesterol. The most common indicator of metabolic syndrome on women with normal BMI was central obesity and low HDL cholesterol. The factors related to the prevalence of metabolic syndrome on women with normal BMI was macronutrient intake.

Positive Association Between Body Mass Index and Hematologic Parameters, Including RBC, WBC and Platelet Count, in Korean Children and Adolescent

2021 ◽  
Author(s):  
Hwal Rim Jeong ◽  
Young Seok Shim
Keyword(s):  
Body Mass Index ◽  
Children And Adolescents ◽  
Body Mass ◽  
Linear Regression Analysis ◽  
Positive Association ◽  
Multiple Linear Regression Analysis ◽  
Normal Weight ◽  
Overweight And Obesity ◽  
Korean Children ◽  
Children And Adolescent

Abstract Objective: To investigate the associations between hematologic parameters and obesity in children and adolescents.Methods: A total of 7,997 subjects (4,259 boys, 3,738 girls) aged 10–18 years was enrolled and hematologic parameters, including WBC, RBC, Hb, Hct, and platelet levels, were recorded and compared against body mass index (BMI) classified into normal-weight, overweight, and obesity groups.Results : The obesity group had significantly higher mean levels of WBC (7.16 vs. 6.16 (x103/mm3), p<0.001), RBC (4.90 vs. 4.82 (x106/mm3), p<0.001), Hb (14.07 vs. 13.99 (g/dL), p<0.05), Hct (42.31 vs. 41.91 (%), p<0.001) and platelets (311.87 vs. 282.66 (x103/mm3), p<0.001) than the normal-weight group after adjusting for obesity and sex. BMI SDS was significantly positively associated with WBC (β=0.275, p<0.001), RBC (β=0.028, p<0.001), Hb (β=0.034, p<0.001), Hct (β=0.152, p<0.001), and platelets (β=8.372, p<0.001) after adjusting for age, sex, and possible socioeconomic confounders in a multiple linear regression analysis.Conclusion: Higher BMI is associated with elevated WBC, RBC, Hb, Hct and platelet counts in children and adolescents. Because higher hematologic parameters are potential risk factors for obesity-related morbidity, more attention should be paid to evaluating and interpreting hematologic parameters in children and adolescents with obesity

Association of sodium intake with insulin resistance in Korean children and adolescents: the Korea National Health and Nutrition Examination Survey 2010

2018 ◽  
Vol 31 (2) ◽  
pp. 117-125 ◽  
Author(s):  
Yong Min Kim ◽  
So Hyun Kim ◽  
Young Suk Shim
Keyword(s):  
Insulin Resistance ◽  
Children And Adolescents ◽  
National Health ◽  
Sodium Intake ◽  
Urinary Sodium ◽  
Nutrition Examination Survey ◽  
Creatinine Ratio ◽  
Korean Children ◽  
Urinary Creatinine ◽  
Health And Nutrition

Abstract Background: This study aimed to evaluate the relationship between sodium intake and insulin resistance indices. Methods: A total of 718 Korean children and adolescents (411 boys) aged 10–18 years who participated in the Korea National Health and Nutrition Examination Survey (KNHANES) were included in the study. The urinary sodium to urinary creatinine ratio was used as a surrogate for sodium intake. The homeostatic model assessment of insulin resistance (HOMA-IR) and the quantitative insulin sensitivity check index (QUICKI) were used as indices of insulin resistance. Results: The mean urinary sodium to urinary creatinine ratio was 11.34 in males and 10.17 in females. The urinary sodium to urinary creatinine ratio was significantly positively correlated with HOMA-IR (r=0.165, p<0.001) and inversely correlated with QUICKI (r=−0.181, p<0.001) in Pearson’s correlation analyses. In a multivariate linear regression analysis, the urinary sodium to urinary creatinine ratio was independently and significantly positively associated with HOMA-IR (β=0.073, p=0.018) and significantly inversely associated with QUICKI (β=−0.080, p=0.007) after adjustment for possible confounders. HOMA-IR was independently and significantly positively associated with the urinary sodium to urinary creatinine ratio (β=0.087, p=0.018), whereas QUICKI was independently and significantly negatively associated with the urinary sodium to urinary creatinine ratio (β=−0.097, p=0.009) after controlling for confounders. Conclusions: Our results suggest that sodium intake, as estimated by the urinary sodium to urinary creatinine ratio, may be independently associated with insulin resistance in children and adolescents.

scholarly journals MON-099 The Association Between C-Reactive Protein, Metabolic Syndrome, and Pre-Diabetes in Korean Children and Adolescents

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Jihyun Kim ◽  
Jong Bin Lee ◽  
Jung Sub Lim
Keyword(s):  
Metabolic Syndrome ◽  
Children And Adolescents ◽  
Geometric Mean ◽  
High Sensitivity ◽  
Low Grade ◽  
C Reactive Protein ◽  
Hscrp Level ◽  
Cross Sectional ◽  
Korean Children ◽  
Reactive Protein

Abstract Objective: Cardiovascular disease (CVD) is a leading cause of death worldwide, including in Korea. In adults, the risk for CVD is increased approximately three-fold in subjects with metabolic syndrome (MetS), and the hazard ratio for subjects with MetS has been reported as 1.37 for mortality from CVD after adjustment for other confounders. Furthermore, MetS in childhood predicts adult MetS and T2DM 25 to 30 years later. Because MetS is a state of chronic low-grade inflammation, measurements of the circulating levels of the inflammatory molecules might provide diagnostic and therapeutic approaches to modulate or alter disease progression. High sensitivity C-reactive protein (hsCRP), a biomarker of inflammation, has emerged as an independent predictor of CVD and T2DM development. The aim of this paper is to evaluate the association between hsCRP and MetS and its components in Korean children and adolescents. Methods: We performed a cross-sectional analysis using data from the Korea National Health and Nutrition Examination Survey (KNHANES) 2016–2017. We analyzed the data of 1,247 subjects (633 males, 14.2 ± 2.7 years) from the KNHANES 2016–2017. MetS were defined by the modified NCEP-ATP III criteria. Results: Among the 1,247 subjects (mean age: 14.2 ± 2.7 years), the prevalence of MetS was 5.8% (7.0% in male subjects and 4.6% in female subjects; p = 0.070). The mean hsCRP level was 0.861 ± 1.567 mg/l (median and interquartile range: 0.370 and 0.430mg/l). Subjects with MetS had higher hsCRP levels than subjects without MetS (geometric mean: 1.08 vs. 0.46 mg/l, p &lt; 0.001). The prevalence of MetS in the lowest, second, third, and highest hsCRP quartiles were 1.8%, 2.4%, 3.5%, and 15.2%, respectively. Compared to the lowest quartile, the odds ratio (OR) for having MetS in the highest quartile was 8.414 (3.272–21.638), adjusting for age and sex. The OR for having abdominal obesity and low HDL-C in the highest quartile were 9.657 (4.818–19.355) and 2.408 (1.286–4.510), adjusting for age, sex, and other components of the MetS. Additionally, the OR for having pre-diabetes (HbA1c ≥ 5.7%) in the highest quartile was 2.061 (1.097–3.870). Conclusion: Serum hsCRP level is positively associated with MetS and pre-diabetes in Korean children and adolescents.

scholarly journals Anthropometric Characteristics, Nutritional Status And Dietary Habits In A College Population

2015 ◽  
Vol 16 (3) ◽  
pp. 241-247 ◽  
Author(s):  
Gora Miljanovic ◽  
Beba Mutavdzic ◽  
Milan Marjanovic ◽  
Zvonko Zivaljevic ◽  
Miljojko Janosevic ◽  
...  
Keyword(s):  
Body Fat ◽  
Dietary Habits ◽  
Eating Habits ◽  
Normal Weight ◽  
Body Fat Percentage ◽  
Nutritional Knowledge ◽  
Fat Percentage ◽  
Food Diary ◽  
Future Health ◽  
Anthropometric Characteristics

Abstract The college student population is prone to irregular food intake and the excessive intake of carbohydrates and snacks. The aim of this study is to investigate the relationships among anthropometric characteristics, dietary habits and nutritional knowledge in female students attending a healthcare college. Our investigation enrolled 100 college students at the High Health School of Professional Studies in Belgrade, 19-30 years old, who underwent anthropometric measurements and an investigation by questionnaire of their nutritional knowledge as well as recorded a 7-day food diary. The results were interpreted in relation to their location of nutritional intake. The majority of students showed good nutritional knowledge. Of the total population, 83% were of normal weight, 11% were overweight, and 5% were underweight. The average Body Mass Index values, as well as body fat percentage, were similar regardless of the type of eating location, but all overweight and obese students were recorded in the groups that ate in the student dining facility and that prepared food and ate by themselves. Students who ate with their families ate significantly fewer fats and proteins but significantly more carbohydrates compared to students in the other two groups. Higher fat intake and snack consumption are significantly related to an increased percentage of body fat. Fruit intake is inversely related to body fat percentage. Despite the relatively low prevalence of overweight, obesity, and underweight in the investigated population, the given results indicate that students may benefit from health promotion activities, increased knowledge and improved eating habits. This is especially important considering that they are future health professionals.

scholarly journals Acylated and nonacylated ghrelin levels and their associations with insulin resistance in obese and normal weight children with metabolic syndrome

2009 ◽  
Vol 161 (6) ◽  
pp. 861-870 ◽  
Author(s):  
Lucia Pacifico ◽  
Eleonora Poggiogalle ◽  
Francesco Costantino ◽  
Caterina Anania ◽  
Flavia Ferraro ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Fasting Blood Glucose ◽  
Tanner Stage ◽  
Normal Subjects ◽  
Normal Weight ◽  
Healthy Children ◽  
Model Assessment ◽  
Obese Children ◽  
The Impact

BackgroundGhrelin, a peptide mainly derived from the stomach, plays a pivotal role in the regulation of food intake, energy metabolism, and storage, as well as in insulin sensitivity. Ghrelin circulates in acylated (A-Ghr) and nonacylated (NA-Ghr) forms, and their potential differential associations with insulin resistance (IR) in childhood obesity remain undefined.ObjectiveWe investigated the associations of ghrelin forms with IR in normal weight and obese children and the impact of metabolic syndrome (MS) on their plasma values.DesignA total of 210 children in four subgroups of normal weight/obese children with and without components of MS were studied. Fasting blood glucose, insulin, lipid profile, and acylated and total ghrelin were examined. IR was determined by a homeostasis model assessment (HOMA) of IR.ResultsIn the entire population, plasma insulin and HOMA-IR were associated negatively with T-Ghr and NA-Ghr, but positively with the ratio of A/NA-Ghr after adjustment for age, gender, and Tanner stage. Obese metabolically abnormal children had lower T-Ghr and NA-Ghr, but comparable A-Ghr and a higher A/NA-Ghr ratio than obese metabolically normal subjects. Compared with lean healthy children, lean metabolically abnormal subjects had higher A-Ghr and the A/NA-Ghr ratio, but comparable T-Ghr and NA-Ghr. A multiple regression analysis showed that A-Ghr and the A/NA-Ghr ratios were positively associated with HOMA-IR, independent of age, gender, Tanner stage, and body mass index (or waist circumference) and other components of MS.ConclusionsA-Ghr excess may negatively modulate insulin action in obese and nonobese children, and may contribute to the association of IR and MS.

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