scholarly journals The antipyretic effect of basil leaf extract (Ocimi sancti folium) in rats

2006 ◽  
Vol 4 (2) ◽  
pp. 65-71
Author(s):  
ANDINA WIDIASTUTI ◽  
YUL MARIYAH ◽  
SUHARSONO SUHARSONO

Basil leaves are believed by community to reduce the fever. This study aimed to determine the effect of antipyretic and the effectiveness of basil leaf extract (Ocimi sancti folium) in rats. This research was a laboratory experimental research by using a random sampling technique. The experimental animal used was Wistar rats aged less than 2 months, as much as 20 rats divided into 4 groups. Group 1 as a negative control group was given aquadest of 2.5 ml, while groups 2, 3 and 4 as test groups were each given basil extract by 3.15 mg/100 gr BB, 6.30 mg mg/100 gr BB and 12.60 mg/100 gr BB, respectively, dissolved in 2.5 ml of aquadest. To increase the temperature, it was injected vaccine DPT 0.2 cc intra-muscular. The temperature measurement is conducted by using a digital thermometer. The data obtained were analyzed by using Statistical Package for Social Sciences 11.5 (SPSS 11.5) with Univariate Analysis of Variance method followed by Post Hoc test. The result of one factor analysis from Univariate Analysis of Variance test showed that the average of rats rectal temperature was significantly different for each test group and for each time range of temperature measurement, each of them was 0.034 and 0.005 with a significant level (α) = 0.05. From the result of analysis by using Post Hoc Test, there was a significant difference between dose group of 3.15 mg/100 gr BB with a dose group of 12.60 mg/100 gr BB and between the time of temperature measurements of 120 minutes and 180 minutes. At first dose and 180th minute, it was obtained a lowest rectal rats temperature. The results showed that the basil leaf extract had an antipyretic effect on rats. The optimal effectiveness evidenced by a lowest average rectal temperature was achieved by a dose of 3.15 mg/100 gr BB at 180th minute.

2017 ◽  
Vol 13 (3) ◽  
pp. 429
Author(s):  
Hussein Salifu ◽  
Gabriel Nyamekye ◽  
Adam Issahaku

This study employed the multivariate analysis of variance (MANOVA) procedure to examine the influence of students’ sex, age and course of study (department) on mathematics performance in Nalerigu Senior High School of the East Mampurisi district in the Northern of Ghana. The results showed that male students perform better on the average for all the mathematics performance indicators (understanding, knowledge and perception). The MANOVA analysis revealed that students performance in mathematics do not differ across sex (gender) and age group. The results however showed that there was significant difference in performance of mathematics across course of study (department). However, the univariate analysis of variance (ANOVA) results revealed that there was no sex difference in understanding and knowledge of mathematics while significant differences exist in perception of mathematics among male and female students. Further, the study revealed a significant difference in students understanding and knowledge in mathematics and no bias in perception of mathematics among students age. The study therefore recommended that, the Ministry of Education, school managements and other stakeholders such as Non Governmental Organizations should sensitize students to discard beliefs and practices that prohibit effective participation of female students which result to poor performance in mathematics.


2019 ◽  
Vol 24 (1) ◽  
pp. 53-61 ◽  
Author(s):  
Thiago Correia Barbosa Lemos ◽  
Juliana de Brito Vasconcelos ◽  
Bianca Mota dos Santos ◽  
Andre Wilson Machado

ABSTRACT Objective: The purpose of this study was to determine the perception of smile esthetics among orthodontists and laypersons with respect to unilateral maxillary canine torque variations in a frontal smile analysis. Methods: Full face and close-up smile photographs of two subjects (1 man and 1 woman) were used. Both smiles displayed healthy maxillary anterior dentitions. The images were digitally altered to obtain a bilateral 0° torque in the maxillary canines. From this image, unilateral variations of the left canine were made with -15°, -10°, -5°, 0°, +5°, +10° and +15°. Final images were randomly assembled into an album that was given to 53 orthodontists and 53 laypersons. Each rater was asked to evaluate the attractiveness of the images using visual analog scales. Data collected were statistically analyzed with one-way analysis of variance with Tukey post-hoc test and the unpaired Student t test. Results: For orthodontists, most attractive smiles were those with 0°, -5° and -10°. For laypersons, most attractive smiles were those with 0°, -5°, -10°, -15° and + 5°. For both groups, the lowest scores were given for the smiles with +10° and +15° torque. When comparing the perceptions of the orthodontists and laypersons, they did not show statistical differences in most situations. Moreover, in general, there was no significant difference between the full-face and close-up assessments of the smiles. Conclusions: The present findings indicated that smiles with unilateral palatal (negative values) maxillary canine torque variations were more tolerated than smiles with buccal crown torque (positive values) variations.


2020 ◽  
pp. 93-99

Background: The cognitiveCognitive dysfunction may be an important factor in smoking and nicotine abuse. However, there are very few studies that have examined the effects of psychiatric conditions on the cognitive flexibility of smokers. Objectives: This research was conducted with the aim of examination theto examine cognitive flexibility (perceive theperceived controllability and cognitive alternatives) ofamong smokers in the context of with social anxiety. MaterialMaterials and methods: The research was a study withpresent causal-comparative design. The populationstudy was allconducted on 60 smoker students ofstudying at Arak University, Arak, Iran, in 2018-2019 years. For selecting the research sample the. The study population was selected using the purposive sampling was usedtechnique. At first, the participants completed the Social Phobia Inventory (SPIN) and Cognitive Flexibility Inventory (CFI).. Then, based on the cutoff point scores of SPIN (19 to above),≤), the participants were divided into two smoker groups (n=30 in each group) were selected: smoker groupsof smokers with and without social anxiety. (n=30 in each group). Finally, these groups were compared in perceive the terms of perceived controllability and cognitive alternatives by Multivariate Analysis of Variance (MANOVA).using the multivariate analysis of variance. Results: The results indicated a significant difference in the linerlinear composition of the dependent variables ofin the two groups (wilks,Wilks’ lambda= 0/.799, F50,2= 6/.726, p= P=0/.004). UnivariateThe results of the univariate analysis of variance indicated that the smoker group with social anxiety had lower perceive theperceived controllability and cognitive alternatives, compared to the smoker group without social anxiety. Conclusion: In generalAs the findings indicated, the level of cognitive flexibility in the smokers with and without social anxiety iswas different. Therefore, it is necessary to consideringconsider the evaluation and treatment of cognitive deficits in smokers based on their level of social anxiety.


2020 ◽  
Vol 5 (1) ◽  
pp. 33
Author(s):  
Dita Puspita Sari ◽  
Didit Aspriyanto ◽  
Irham Taufiqurrahman

Background: Caries is a disease that occurs because of the fermentation carbohydrates process by microorganisms in the oral cavity. One of the bacteria that causes caries is Streptococcus sanguinis. These bacteria will colonize on the tooth surface, then form dental plaques and contribute to the causes of caries and other periodontal diseases. Kasturi leaf extract (Mangifera casturi) has various compounds such as tannins, terpenoids, alkaloids, and flavonoids that have antimicrobial substances. Purpose: The aim of this study was to determine antibacterial effectivity of kasturi leaf extract (Mangifera casturi) against the growth of Streptococcus sanguinis bacteria. Method: This research was an experimental method laboratory (true experimental), with a randomized pre test and post test with control group design using 5 treatments: kasturi leaf extract (concentration: 20 mg/ml, 25 mg/ml, and 30 mg/ml); and two groups of control: positive control and negative control. Each treatment was repeated 5 times. Antibacterial activity testing used a liquid dilution method. Measurement of minimum inhibitory concentration (MIC) used a Uv-Vis Spectrophotometer and measurement of the minimum bactericidal concentration (MBC) used a colony counter. The MIC data were analyzed using One Way Anova and continued with the Dunnet Post Hoc test. MBC data were analyzed using the Kruskal-Wallis test and continued with the Mann-Whitney Post Hoc test. Result: One-Way Anova test showed that MIC had a significant difference, and the Kruskal-Wallis test showed that MBC also had significant differences. MIC was obtained at the concentration of 20 mg/ml and MBC was obtained at the concentration of 30 mg / ml. Conclusion: There is antibacterial effectiveness in kasturi leaf extract (Mangifera casturi) against the growth of Streptococcus sanguinis.


2012 ◽  
Vol 83 (1) ◽  
pp. 110-116 ◽  
Author(s):  
Valmy Pangrazio-Kulbersh ◽  
Brynn Jezdimir ◽  
Mariana de Deus Haughey ◽  
Richard Kulbersh ◽  
Paul Wine ◽  
...  

Abstract Objective: To evaluate the maxillary alveolar buccal bone levels after expansion with banded and bonded expanders, using cone-beam computed tomography (CBCT). Materials and Methods: The population sample consisted of 22 patients who required expansion during their comprehensive treatment; 10 patients (five males and five females) with a mean age of 13.5 years (CVMS 3) had bonded hygienic expanders, and 12 (six males and six females) with a mean age of 12.6 years (CVMS 3) had banded hyrax expanders. CBCT was taken both before (T1) and 6 months after last activation (T2). Measurements were made for buccal bone thickness (BT), buccal marginal bone level (MBL), and bone thickness level (BTL) at the right first molar (MRt), left first molar (MLft), right first premolar (PMRt), and left first premolar (PMLft). A mixed-design analysis of variance assessed differences between and within the groups. Post hoc t-tests were completed on significant analysis of variance results to determine where differences occurred. Results: Analysis of variance revealed no significant differences between or within the two groups. BT significantly decreased horizontally following rapid maxillary expansion. The amount of bone lost was −0.59 mm MRt, −0.72 mm PMRt, −0.50 mm MLft, and −0.57 mm PMLft (P < .003). Conclusions: There was no significant difference between or within the two groups. Buccal bone loss in the vertical dimension (MBL) only showed significance in the banded group for MRt (0.63 mm) and PMLFt (0.37 mm) as evidenced by the paired t-test (P < .05).


2021 ◽  
pp. 030573562198897
Author(s):  
Aaron Lohmeyer

The primary purposes of this study were (1) to determine the effect of three encoding conditions (singing, playing, studying silently) on participants’ music memorization accuracy; (2) to examine potential differences between choral, jazz, and concert band musicians’ accuracy in completing the music memorization task; and (3) to determine whether ensemble affiliation yielded any performance advantages among the three presentation conditions. Three folk melodies were selected for memorization under the three encoding conditions. Participants ( N = 81) had 75 s to commit each melody to memory while studying silently, singing, or playing on a keyboard. Participants then notated the three melodies using conventional staff notation. A two-way analysis of variance (ANOVA) with repeated measures on one factor revealed significant differences based on participants’ ensemble affiliation. A Tukey’s honest significant difference (HSD) post hoc test revealed the jazz group had higher accuracy scores than the band group. No significant differences were found based on encoding conditions, and no significant interactions were found between the encoding conditions and ensemble groups. The experiment is framed by questions related to memory, reading, and differing notions of literacy.


Author(s):  
Ayşe Tuğba Ertürk-Avunduk ◽  
Seçkin Aksu ◽  
Ebru Delikan

Objective: This study investigated the effects of three types of mouthwash on the color stability of three resin-based restorative materials (nanohybrid resin composite, sonic-activated bulk-fill material, and compomer). Materials and Methods: To this end, 120 cylindrical disc specimens were prepared and polished, after which they were incubated in distilled water for 24 hours for post-polymerization. The baseline color values of each specimen were measured with a spectrophotometer, then the specimens were randomly divided into four groups. Following immersion in the mouthwashes for 24 hours, the specimens were rinsed with distilled water and dried before the color measurement was repeated. The values of color change (∆E₀₀) were subsequently calculated. A two-way analysis of variance and Duncan’s post hoc multiple comparison tests were conducted to determine statistically significant differences among the restorative materials. Results: All samples showed discoloration after immersion, albeit some instances of discoloration were imperceptible. In this respect, a statistically significant difference was found among the restorative materials and mouthwashes (p<0.05). Imperceptible ∆E₀₀ values were derived on the nanohybrid resin composite and compomer, but perceptible and acceptable ∆E₀₀ values were detected on the sonic-activated bulk-fill materials (p<0.05). The clinically unacceptable discoloration was observed on the sonic-activated bulk-fill composite immersed in Listerine®. Conclusions: Clinicians should make recommendations based on the potential staining capacity of mouthwashes prescribed for daily use in restorative materials. In this way, the need for renewal of restorations due to discoloration could be avoided.


PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0247716
Author(s):  
Yasemin Dziuk ◽  
Sachin Chhatwani ◽  
Stephan C. Möhlhenrich ◽  
Sabrina Tulka ◽  
Ella A. Naumova ◽  
...  

Introduction Development of white spot lesions (WSLs) during orthodontic treatment is a common risk factor. Fixation of the orthodontic appliances with glass ionomer cements could reduce the prevalence of WSL’s due to their fluoride release capacities. The purpose of this study was to evaluate differences of fluoride release properties from resin-modified and conventional glass ionomer cements (GICs). Methods The resin-modified GICs Fuji ORTHO LC (GC Orthodontics), Meron Plus QM (VOCO), as well as the conventional GICs Fuji ORTHO (GC Orthodontics), Meron (VOCO) and Ketac Cem Easymix (3M ESPE) were tested in this study. The different types of GICs were applied to hydroxyapatite discs according to the manufacturer’s instructions and stored in a solution of TISAB III (Total Ionic Strength Adjustment Buffer III) and fluoride-free water at 37°C. Fluoride measurements were made after 5 minutes, 2 hours, 24 hours, 14 days, 28 days, 2 months, 3 months and 6 months. One factor analysis of variance (ANOVA) was used for the overall comparison of the cumulative fluoride release (from measurement times of 5 minutes to 6 months) between the different materials with the overall level of significance set to 0.05. Tukey’s post hoc test was used for post hoc pairwise comparisons in the cumulative fluoride release between the different materials. Results The cumulative fluoride release (mean ± sd) in descending order was: Fuji ORTHO LC (221.7 ± 10.29 ppm), Fuji ORTHO (191.5 ± 15.03 ppm), Meron Plus QM (173.0 ± 5.89 ppm), Meron (161.3 ± 7.84 ppm) and Ketac Cem Easymix (154.6 ± 6.09 ppm) within 6 months. Analysis of variance detected a significant difference in the cumulative fluoride release between at least two of the materials (rounded p-value < 0.001). Pairwise analysis with Tukey’s post hoc test showed a significant difference in the cumulative fluoride release for all the comparisons except M and MPQM (p = 0.061) and KCE and M (p = 0.517). Conclusion Fluoride ions were released cumulatively over the entire test period for all products. When comparing the two products from the same company (Fuji ORTHO LC vs. Fuji ORTHO from GC Orthodontics Europe GmbH and Meron Plus QM vs. Meron from VOCO GmbH, Mannheim, Germany), it can be said that the resin-modified GICs have a higher release than conventional GICs. The highest individual fluoride release of all GICs was at 24 hours. A general statement, whether resin-modified or conventional GICs have a higher release of fluoride cannot be made.


2018 ◽  
Vol 33 (3) ◽  
pp. 262-266 ◽  
Author(s):  
Joshua Garcia ◽  
Megan Pintens ◽  
Amanda Morris ◽  
Paul Takamoto ◽  
Laura Baumgartner ◽  
...  

Background: Using a reduced dose of 5 units of regular insulin has been proposed as a strategy to mitigate the risk of hypoglycemia when treating hyperkalemia. The comparative efficacy and safety of this strategy to conventional 10 units is not well established. Objective: To compare the effectiveness of reduced and conventional dosed insulin for hyperkalemia treatment. Methods: Electronic medication administration reports of conventional or reduced doses of insulin given for hyperkalemia treatment were reviewed from July 2013 to September 2015. The primary outcome was reduction in serum potassium. Results: Ninety-two administrations of reduced dose insulin and 309 administrations of conventional dose insulin were included. No significant difference was found in potassium reduction between the groups (−0.096 mmol/L, P value = .2210). Post hoc subgroup analysis of patients with serum potassium > 6 mmol/L revealed a lower reduction in potassium in the reduced dose group compared to the conventional dose group (difference: −0.238 mmol/L, P value = .018). Conclusions Conventional dose insulin may be more effective than reduced dose regular insulin at baseline serum potassium levels >6 mmol/L in the treatment of hyperkalemia. Frequent monitoring of serum potassium and glucose after administration of insulin is necessary to confirm adequate response and avoidance of hypoglycemia.


2018 ◽  
Vol 6 (2) ◽  
pp. 129-135
Author(s):  
Intan Kartika Sari

This study aimed to reveal: (1) the effect of PBL on the achievement motivation; (2) the effect of PjBL on the achievement motivation; and (3) differences of achievement motivation between the group taught using PBL and the group taught using PjBL. This study was a quasi experiment with the nonequivalent commparison group design. The population was grade V students of SD Negeri Lempuyangwangi in academic year 2016/2017. The data analysis used t-test and Univariate Analysis of Variance at the significant levelof 5%. The result are as follows: (1) PBL improved positively and significantly on theachievement motivation; (2) PjBL improved positively and significantly on theachievement motivation; and (3) there is a significant difference on theachievement motivation between the group taught using PBL and that taught using PjBL.


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